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Select item 107122781.

Global and age-related neuroanatomical abnormalities in a Pax6-deficient mouse model of aniridia suggests a role for Pax6 in adult structural neuroplasticity

Madison K. Grant, Anastasia M. Bobilev, Ashley M. Rasys, J. Branson Byers, Hannah C. Schriever, Khan Hekmatyar, James D. Lauderdale

Brain Res. Author manuscript; available in PMC 2023 Dec 11.

Published in final edited form as: Brain Res. 2020 Apr 1; 1732: 146698. Published online 2020 Jan 31. doi: 10.1016/j.brainres.2020.146698

PMCID:: PMC10712278

Abstract Article PDF–1.7M

Select item 97045522.

Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains

Nurfarhana Ferdaos, Sally Lowell, John O. Mason

PLoS One. 2022; 17(11): e0278147. Published online 2022 Nov 28. doi: 10.1371/journal.pone.0278147

PMCID:: PMC9704552

Abstract Article PDF–2.9M

Select item 90509353.

Long-term retinal protection by MEK inhibition in Pax6 haploinsufficiency mice

James D. Cole, Kara M. McHaney, Behnam Rabiee, Jingyi Gao, Carlos Rodriguez, David A. Miller, Mingna Liu, Marta Grannonico, Pedro Norat, Hao F. Zhang, Ali R. Djalilian, Xiaorong Liu

Exp Eye Res. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Exp Eye Res. 2022 May; 218: 109012. Published online 2022 Mar 1. doi: 10.1016/j.exer.2022.109012

PMCID:: PMC9050935

Abstract Article PDF–2.0M

Select item 89770984.

Pax6 loss alters the morphological and electrophysiological development of mouse prethalamic neurons

Tian Tian, Idoia Quintana-Urzainqui, Zrinko Kozić, Thomas Pratt, David J. Price

Development. 2022 Mar 15; 149(6): dev200052. Published online 2022 Mar 17. doi: 10.1242/dev.200052

PMCID:: PMC8977098

Abstract Article

Select item 78683635.

PAX6 missense variants in two families with isolated foveal hypoplasia and nystagmus: evidence of paternal postzygotic mosaicism

Dulce Lima Cunha, Nicholas Owen, Vijay Tailor, Marta Corton, Maria Theodorou, Mariya Moosajee

Eur J Hum Genet. 2021 Feb; 29(2): 349–355. Published online 2020 Oct 6. doi: 10.1038/s41431-020-00737-1

PMCID:: PMC7868363

Abstract Article PDF–1.8M

Select item 75992536.

PAX6 mutation alters circadian rhythm and β cell function in mice without affecting glucose tolerance

Nirav Florian Chhabra, Oana Veronica Amarie, Moya Wu, Anna-Lena Amend, Marina Rubey, Daniel Gradinger, Martin Irmler, Johannes Beckers, Birgit Rathkolb, Eckhard Wolf, Annette Feuchtinger, Peter Huypens, Raffaele Teperino, Jan Rozman, Gerhard K. H. Przemeck, Martin Hrabě de Angelis

Commun Biol. 2020; 3: 628. Published online 2020 Oct 30. doi: 10.1038/s42003-020-01337-x

PMCID:: PMC7599253

Abstract Article PDF–3.7M

Select item 71146257.

Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia

Seyedeh Zeinab Mirjalili Mohanna, Jack W. Hickmott, Siu Ling Lam, Nina Y. Chiu, Tess C. Lengyell, Beatrice M. Tam, Orson L. Moritz, Elizabeth M. Simpson

Mol Ther Methods Clin Dev. 2020 Jun 12; 17: 478–490. Published online 2020 Mar 14. doi: 10.1016/j.omtm.2020.03.002

PMCID:: PMC7114625

Abstract Article PDF–2.9M

Select item 67248418.

Pax6 Is Required for Making Specific Subpopulations of Granule and Periglomerular Neurons in the Olfactory Bulb

Minoree Kohwi, Noriko Osumi, John L. R. Rubenstein, Arturo Alvarez-Buylla

J Neurosci. 2005 Jul 27; 25(30): 6997–7003. doi: 10.1523/JNEUROSCI.1435-05.2005

PMCID:: PMC6724841

Abstract Article PDF–392K

Select item 66704479.

The Neurogenesis-Controlling Factor, Pax6, Inhibits Proliferation and Promotes Maturation in Murine Astrocytes

Katsuyasu Sakurai, Noriko Osumi

J Neurosci. 2008 Apr 30; 28(18): 4604–4612. doi: 10.1523/JNEUROSCI.5074-07.2008

PMCID:: PMC6670447

Abstract Article PDF–727K

Select item 628636910.

In Vivo Evaluation of PAX6 Overexpression and NMDA Cytotoxicity to Stimulate Proliferation in the Mouse Retina

Ehsan Ranaei Pirmardan, Zahra-Soheila Soheili, Shahram Samiei, Hamid Ahmadieh, Seyed Javad Mowla, Marzieh Naseri, Narsis Daftarian

Sci Rep. 2018; 8: 17700. Published online 2018 Dec 7. doi: 10.1038/s41598-018-35884-5

PMCID:: PMC6286369

Abstract Article PDF–2.1M

Select item 623840911.

Mapping the Pax6 3’ untranslated region microRNA regulatory landscape

Bridget C. Ryan, Kieran Lowe, Laura Hanson, Talveen Gil, Lauren Braun, Perry L. Howard, Robert L. Chow

BMC Genomics. 2018; 19: 820. Published online 2018 Nov 15. doi: 10.1186/s12864-018-5212-x

PMCID:: PMC6238409

Abstract Article PDF–2.7M

Select item 588249112.

Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis

Liv Aleen Remez, Akishi Onishi, Yotam Menuchin-Lasowski, Assaf Biran, Seth Blackshaw, Karl J. Wahlin, Donlad J. Zack, Ruth Ashery-Padan

Dev Biol. Author manuscript; available in PMC 2018 Dec 1.

Published in final edited form as: Dev Biol. 2017 Dec 1; 432(1): 140–150. Published online 2017 Oct 7. doi: 10.1016/j.ydbio.2017.09.030

PMCID:: PMC5882491

Abstract Article PDF–2.7M

Select item 544812313.

The transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca²⁺ dynamics in adult mice

Ryan K. Mitchell, Marie-Sophie Nguyen-Tu, Pauline Chabosseau, Rebecca M. Callingham, Timothy J. Pullen, Rebecca Cheung, Isabelle Leclerc, David J. Hodson, Guy A. Rutter

J Biol Chem. 2017 May 26; 292(21): 8892–8906. Published online 2017 Apr 4. doi: 10.1074/jbc.M117.784629