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Select item 103938181.

Hepatic protein kinase Cbeta deficiency mitigates late-onset obesity

Yaoling Shu, Nikhil Gumma, Faizule Hassan, Daniel A. Branch, Lisa A. Baer, Michael C. Ostrowski, Kristin I. Stanford, Kedryn K. Baskin, Kamal D. Mehta

J Biol Chem. 2023 Aug; 299(8): 104917. Published online 2023 Jun 12. doi: 10.1016/j.jbc.2023.104917

PMCID:: PMC10393818

Article PDF–2.0M

Select item 85256382.

Role of hepatic PKCβ in nutritional regulation of hepatic glycogen synthesis

Yaoling Shu, Faizule Hassan, Michael C. Ostrowski, Kamal D. Mehta

JCI Insight. 2021 Oct 8; 6(19): e149023. Published online 2021 Oct 8. doi: 10.1172/jci.insight.149023

PMCID:: PMC8525638

Article PDF–1.1M

Select item 74031463.

A novel transgenic mouse strain expressing PKCβII demonstrates expansion of B1 and marginal zone B cell populations

Ali A. Azar, Alison M. Michie, Anuradha Tarafdar, Natasha Malik, Geetha K. Menon, Kathleen J. Till, Nikolina Vlatković, Joseph R. Slupsky

Sci Rep. 2020; 10: 13156. Published online 2020 Aug 4. doi: 10.1038/s41598-020-70191-y

PMCID:: PMC7403146

Article PDF–4.3M

Select item 71163654.

Stromal cell Protein kinase C-β inhibition enhances chemosensitivity in B cell malignancies and overcomes drug resistance

Eugene Park, Jingyu Chen, Andrew Moore, Maurizio Mangolini, Antonella Santoro, Joseph R. Boyd, Hilde Schjerven, Veronika Ecker, Maike Buchner, James C. Williamson, Paul J. Lehner, Luca Gasparoli, Owen Williams, Johannes Bloehdorn, Stephan Stilgenbauer, Michael Leitges, Alexander Egle, Marc Schmidt-Supprian, Seth Frietze, Ingo Ringshausen

Sci Transl Med. Author manuscript; available in PMC 2020 Nov 17.

Published in final edited form as: Sci Transl Med. 2020 Jan 15; 12(526): eaax9340. Published online 2020 Jan 15. doi: 10.1126/scitranslmed.aax9340

PMCID:: PMC7116365

Article PDF–3.1M

Select item 67726115.

A Role for the β Isoform of Protein Kinase C in Fear Conditioning

Edwin J. Weeber, Coleen M. Atkins, Joel C. Selcher, Andrew W. Varga, Banafsheh Mirnikjoo, Richard Paylor, Michael Leitges, J. David Sweatt

J Neurosci. 2000 Aug 15; 20(16): 5906–5914. doi: 10.1523/JNEUROSCI.20-16-05906.2000

PMCID:: PMC6772611

Article PDF–261K

Select item 64224986.

PKCβ1 regulates meiotic cell cycle in mouse oocyte

Zi-Yun Yi, Qiu-Xia Liang, Tie-Gang Meng, Jian Li, Ming-Zhe Dong, Yi Hou, Ying-Chun Ouyang, Chun-Hui Zhang, Heide Schatten, Qing-Yuan Sun, Jie Qiao, Wei-Ping Qian

Cell Cycle. 2019; 18(4): 395–412. Published online 2019 Feb 7. doi: 10.1080/15384101.2018.1564492

PMCID:: PMC6422498

Article PDF–2.7M

Select item 49469177.

Autocrine Signaling Underlies Fast Repetitive Plasma Membrane Translocation of Conventional and Novel Protein Kinase C Isoforms in β Cells

Anne Wuttke, Qian Yu, Anders Tengholm

J Biol Chem. 2016 Jul 15; 291(29): 14986–14995. Published online 2016 May 20. doi: 10.1074/jbc.M115.698456

PMCID:: PMC4946917

Article PDF–1.1M

Select item 48770148.

Inhibition of Cardiac Kir Current (I_K1) by Protein Kinase C Critically Depends on PKCβ and Kir2.2

Daniel Scherer, Claudia Seyler, Panagiotis Xynogalos, Eberhard P. Scholz, Dierk Thomas, Johannes Backs, Martin Andrassy, Mirko Völkers, Christoph A. Karle, Hugo A. Katus, Edgar Zitron

PLoS One. 2016; 11(5): e0156181. Published online 2016 May 23. doi: 10.1371/journal.pone.0156181

PMCID:: PMC4877014

Article PDF–917K

Select item 48241569.

Hydrophobic motif site-phosphorylated protein kinase CβII between mTORC2 and Akt regulates high glucose-induced mesangial cell hypertrophy

Falguni Das, Nandini Ghosh-Choudhury, Meenalakshmi M. Mariappan, Balakuntalam S. Kasinath, Goutam Ghosh Choudhury

Am J Physiol Cell Physiol. 2016 Apr 1; 310(7): C583–C596. Published online 2016 Jan 6. doi: 10.1152/ajpcell.00266.2015

PMCID:: PMC4824156

Article

Select item 421376610.

PKCβ Positively Regulates RANKL-Induced Osteoclastogenesis by Inactivating GSK-3β

Jihye Shin, Hyunduk Jang, Jingjing Lin, Soo Young Lee

Mol Cells. 2014 Oct 31; 37(10): 747–752. Published online 2014 Sep 26. doi: 10.14348/molcells.2014.0220

PMCID:: PMC4213766

Article PDF–842K

Select item 385718811.

Exercise Protects against Diet-Induced Insulin Resistance through Downregulation of Protein Kinase Cβ in Mice

Xiaoquan Rao, Jixin Zhong, Xiaohua Xu, Brianna Jordan, Santosh Maurya, Zachary Braunstein, Tse-Yao Wang, Wei Huang, Sudha Aggarwal, Muthu Periasamy, Sanjay Rajagopalan, Kamal Mehta, Qinghua Sun

PLoS One. 2013; 8(12): e81364. Published online 2013 Dec 9. doi: 10.1371/journal.pone.0081364

PMCID:: PMC3857188

Article PDF–2.2M

Select item 382312212.

Enforced expression of protein kinase C in skeletal muscle causes physical inactivity, fatty liver and insulin resistance in the brain

Anita M Hennige, Martin Heni, Jürgen Machann, Harald Staiger, Tina Sartorius, Miriam Hoene, Rainer Lehmann, Cora Weigert, Andreas Peter, Antje Bornemann, Stefan Kroeber, Anna Pujol, Sylvie Franckhauser, Fatima Bosch, Fritz Schick, Reiner Lammers, Hans-Ulrich Häring

J Cell Mol Med. 2010 Apr; 14(4): 903–913. Published online 2008 Dec 24. doi: 10.1111/j.1582-4934.2008.00629.x

PMCID:: PMC3823122

Article PDF–761K

Select item 376752413.

Protein kinase Cβ as a therapeutic target stabilizing blood–brain barrier disruption in experimental autoimmune encephalomyelitis

Tobias V. Lanz, Simon Becker, Matthias Osswald, Stefan Bittner, Michael K. Schuhmann, Christiane A. Opitz, Sadanand Gaikwad, Benedikt Wiestler, Ulrike M. Litzenburger, Felix Sahm, Martina Ott, Simeon Iwantscheff, Carl Grabitz, Michel Mittelbronn, Andreas von Deimling, Frank Winkler, Sven G. Meuth, Wolfgang Wick, Michael Platten

Proc Natl Acad Sci U S A. 2013 Sep 3; 110(36): 14735–14740. Published online 2013 Aug 19. doi: 10.1073/pnas.1302569110

PMCID:: PMC3767524

Article PDF–976K

Select item 367647314.

Heterozygous mis-sense mutations in Prkcb as a critical determinant of anti-polysaccharide antibody formation

CE Teh, K Horikawa, CN Arnold, B Beutler, EM Kucharska, CG Vinuesa, EM Bertram, CC Goodnow, A Enders

Genes Immun. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Genes Immun. 2013 Jun; 14(4): 223–233. Published online 2013 Apr 4. doi: 10.1038/gene.2013.11

PMCID:: PMC3676473

Article PDF–912K

Select item 313839815.

Reduction of PKCβII Activity in Smooth Muscle Cells Attenuates Acute Arterial Injury

Chun Huang, Jong Sun Chang, Yunlu Xu, Qing Li, Yu Shan Zou, Shi-Fang Yan

Atherosclerosis. Author manuscript; available in PMC 2011 Sep 1.

Published in final edited form as: Atherosclerosis. 2010 Sep; 212(1): 123–130. Published online 2010 Jun 4. doi: 10.1016/j.atherosclerosis.2010.05.039