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Select item 106177681.

A PPARγ/long noncoding RNA axis regulates adipose thermoneutral remodeling in mice

Zhengyi Zhang, Ya Cui, Vivien Su, Dan Wang, Marcus J. Tol, Lijing Cheng, Xiaohui Wu, Jason Kim, Prashant Rajbhandari, Sicheng Zhang, Wei Li, Peter Tontonoz, Claudio J. Villanueva, Tamer Sallam

J Clin Invest. 2023 Nov 1; 133(21): e170072. Published online 2023 Nov 1. doi: 10.1172/JCI170072

PMCID:: PMC10617768

Article PDF–3.3M

Select item 106171192.

Swimming exercise ameliorates insulin resistance and nonalcoholic fatty liver by negatively regulating PPARγ transcriptional network in mice fed high fat diet

Yong Zhang, Jie Xu, Di Zhou, Tingting Ye, Puqing Zhou, Zuofeng Liu, Xinyuan Liu, Zinan Wang, Tianmiao Hua, Zhenghao Zhang, Qingyan Sun

Mol Med. 2023; 29: 150. Published online 2023 Oct 31. doi: 10.1186/s10020-023-00740-4

PMCID:: PMC10617119

Article PDF–4.3M

Select item 104995693.

PPARG stimulation restored lung mRNA expression of core clock, inflammation‐ and metabolism‐related genes disrupted by reversed feeding in male mice

Oksana Shlykova, Olga Izmailova, Alina Kabaliei, Vitalina Palchyk, Viktoriya Shynkevych, Igor Kaidashev

Physiol Rep. 2023 Sep; 11(17): e15823. Published online 2023 Sep 13. doi: 10.14814/phy2.15823

PMCID:: PMC10499569

Article PDF–4.7M

Select item 104326614.

PPARγ activation modulates the balance of peritoneal macrophage populations to suppress ovarian tumor growth and tumor-induced immunosuppression

Mélissa Prat, Kimberley Coulson, Clément Blot, Godefroy Jacquemin, Mathilde Romano, Marie-Laure Renoud, Mohamad AlaEddine, Augustin Le Naour, Hélène Authier, Mouna Chirine Rahabi, Khaddouj Benmoussa, Marie Salon, Mélissa Parny, Jean-Pierre Delord, Gwenaël Ferron, Lise Lefèvre, Bettina Couderc, Agnès Coste

J Immunother Cancer. 2023; 11(8): e007031. Published online 2023 Aug 16. doi: 10.1136/jitc-2023-007031

PMCID:: PMC10432661

Article PDF–2.6M

Select item 102172335.

PPARγ Acetylation in Adipocytes Exacerbates BAT Whitening and Worsens Age-Associated Metabolic Dysfunction

Ying He, Ruotong Zhang, Lexiang Yu, Tarik Zahr, Xueming Li, Tae-Wan Kim, Li Qiang

Cells. 2023 May; 12(10): 1424. Published online 2023 May 18. doi: 10.3390/cells12101424

PMCID:: PMC10217233

Article PDF–3.1M

Select item 100826756.

Hepatocyte PPARγ contributes to the progression of non-alcoholic steatohepatitis in male and female obese mice

Samuel M. Lee, Jose Muratalla, Saman Karimi, Alberto Diaz-Ruiz, Maria Dolores Frutos, Grace Guzman, Bruno Ramos-Molina, Jose Cordoba-Chacon

Cell Mol Life Sci. Author manuscript; available in PMC 2024 Jan 11.

Published in final edited form as: Cell Mol Life Sci. 2023 Jan 11; 80(2): 39. Published online 2023 Jan 11. doi: 10.1007/s00018-022-04629-z

PMCID:: PMC10082675

Article PDF–3.7M

Select item 100486187.

Role of hepatic peroxisome proliferator-activated receptor γ in NAFLD

Samuel M. Lee, Jose Muratalla, Marta Sierra-Cruz, Jose Cordoba-Chacon

J Endocrinol. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: J Endocrinol. 2023 Apr 1; 257(1): e220155. Published online 2023 Mar 10. doi: 10.1530/JOE-22-0155

PMCID:: PMC10048618

Article PDF–1.0M

Select item 98398518.

PPARγ Acetylation Orchestrates Adipose Plasticity and Metabolic Rhythms

Ying He, Alana B'nai Taub, Lexiang Yu, Yifan Yao, Ruotong Zhang, Tarik Zahr, Nicole Aaron, Joseph LeSauter, Lihong Fan, Longhua Liu, Ruya Tazebay, Jianwen Que, Utpal Pajvani, Liheng Wang, Rae Silver, Li Qiang

Adv Sci (Weinh) 2023 Jan; 10(2): 2204190. Published online 2022 Nov 17. doi: 10.1002/advs.202204190

PMCID:: PMC9839851

Article PDF–3.5M

Select item 85457199.

The Role of PPAR-γ in Allergic Disease

Julian M. Stark, Jonathan M. Coquet, Christopher A. Tibbitt

Curr Allergy Asthma Rep. 2021; 21(11): 45. Published online 2021 Oct 25. doi: 10.1007/s11882-021-01022-x

PMCID:: PMC8545719

Article PDF–856K

Select item 846743110.

Sex Dimorphism of Nonalcoholic Fatty Liver Disease (NAFLD) in Pparg-Null Mice

Mariano Schiffrin, Carine Winkler, Laure Quignodon, Aurélien Naldi, Martin Trötzmüller, Harald Köfeler, Hugues Henry, Paolo Parini, Béatrice Desvergne, Federica Gilardi

Int J Mol Sci. 2021 Sep; 22(18): 9969. Published online 2021 Sep 15. doi: 10.3390/ijms22189969

PMCID:: PMC8467431

Article PDF–3.3M

Select item 845087011.

Pulmonary Hypertension in Obese Mice Is Accompanied by a Reduction in PPAR-γ Expression in Pulmonary Artery

Any Elisa de Souza Schmidt Gonçalves, Guilherme Zweig Rocha, Rodrigo Marin, Rafael Ludemann Camargo, Andrey dos Santos, Helison do Carmo, Dioze Guadagnini, Orlando Petrucci, Zenaide Providello Moysés, Vera Maria Cury Salemi, Alexandre Gabarra Oliveira, Mario José Abdalla Saad

Front Endocrinol (Lausanne) 2021; 12: 701994. Published online 2021 Sep 6. doi: 10.3389/fendo.2021.701994

PMCID:: PMC8450870

Article PDF–1.9M

Select item 842829512.

Rosiglitazone Requires Hepatocyte PPARγ Expression to Promote Steatosis in Male Mice With Diet-Induced Obesity

Samuel M Lee, Jose Muratalla, Alberto Diaz-Ruiz, Pablo Remon-Ruiz, Maximilian McCann, Chong W Liew, Rhonda D Kineman, Jose Cordoba-Chacon

Endocrinology. 2021 Nov; 162(11): bqab175. Published online 2021 Aug 21. doi: 10.1210/endocr/bqab175

PMCID:: PMC8428295

Article

Select item 839547313.

Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin

Raymond L. Konger, Ethel Derr-Yellin, Teresa A. Zimmers, Terrence Katona, Xiaoling Xuei, Yunlong Liu, Hong-Ming Zhou, Ed Ronald Simpson, Jr., Matthew J. Turner

Int J Mol Sci. 2021 Aug; 22(16): 8634. Published online 2021 Aug 11. doi: 10.3390/ijms22168634

PMCID:: PMC8395473

Article PDF–2.9M

Select item 826035414.

Breast cancer-associated skeletal muscle mitochondrial dysfunction and lipid accumulation is reversed by PPARG

Hannah E. Wilson, David A. Stanton, Stephanie Rellick, Werner Geldenhuys, Emidio E. Pistilli

Am J Physiol Cell Physiol. 2021 Apr 1; 320(4): C577–C590. Published online 2021 Jan 13. doi: 10.1152/ajpcell.00264.2020

PMCID:: PMC8260354

Article

Select item 825597415.

Acidic Microenvironment Aggravates the Severity of Hepatic Ischemia/Reperfusion Injury by Modulating M1-Polarization Through Regulating PPAR-γ Signal

Wei Ding, Yunfei Duan, Zhen Qu, Jiawei Feng, Rongsheng Zhang, Xiaodong Li, Donglin Sun, Xiaoying Zhang, Yunjie Lu

Front Immunol. 2021; 12: 697362. Published online 2021 Jun 21. doi: 10.3389/fimmu.2021.697362

PMCID:: PMC8255974

Article PDF–2.9M

Select item 821145116.

Arachidonic Acid Metabolism Controls Macrophage Alternative Activation Through Regulating Oxidative Phosphorylation in PPARγ Dependent Manner

Miao Xu, Xiaohong Wang, Yongning Li, Xue Geng, Xudong Jia, Lishi Zhang, Hui Yang

Front Immunol. 2021; 12: 618501. Published online 2021 Jun 3. doi: 10.3389/fimmu.2021.618501

PMCID:: PMC8211451

Article PDF–3.0M

Select item 815970017.

PPARγ agonists promote the resolution of myelofibrosis in preclinical models

Juliette Lambert, Joseph Saliba, Carolina Calderon, Karine Sii-Felice, Mohammad Salma, Valérie Edmond, Jean-Claude Alvarez, Marc Delord, Caroline Marty, Isabelle Plo, Jean-Jacques Kiladjian, Eric Soler, William Vainchenker, Jean-Luc Villeval, Philippe Rousselot, Stéphane Prost

J Clin Invest. 2021 Jun 1; 131(11): e136713. Published online 2021 Jun 1. doi: 10.1172/JCI136713

PMCID:: PMC8159700

Article PDF–8.6M

Select item 807609118.

PPARG in osteocytes controls sclerostin expression, bone mass, marrow adiposity and mediates TZD-induced bone loss

Sudipta Baroi, Piotr J. Czernik, Amit Chougule, Patrick R. Griffin, Beata Lecka-Czernik

Bone. Author manuscript; available in PMC 2022 Jun 1.

Published in final edited form as: Bone. 2021 Jun; 147: 115913. Published online 2021 Mar 16. doi: 10.1016/j.bone.2021.115913

PMCID:: PMC8076091

Article PDF–2.9M

Select item 800854819.

PPARγ activation improves the microenvironment of perivascular adipose tissue and attenuates aortic stiffening in obesity

Ju-Yi Chen, Yi-Pin Wu, Chih-Yi Li, Huei-Fen Jheng, Ling-Zhen Kao, Ching-Chun Yang, Sy-Ying Leu, I-Chia Lien, Wen-Tsan Weng, Haw-Chih Tai, Yu-Wei Chiou, Ming-Jer Tang, Pei-Jane Tsai, Yau-Sheng Tsai

J Biomed Sci. 2021; 28: 22. Published online 2021 Mar 29. doi: 10.1186/s12929-021-00720-y

PMCID:: PMC8008548

Article PDF–7.7M

Select item 800581920.

Hepatocyte-Specific Loss of PPARγ Protects Mice From NASH and Increases the Therapeutic Effects of Rosiglitazone in the Liver

Samuel M. Lee, Carolina M. Pusec, Gregory H. Norris, Adam De Jesus, Alberto Diaz-Ruiz, Jose Muratalla, Andre Sarmento-Cabral, Grace Guzman, Brian T. Layden, Jose Cordoba-Chacon

Cell Mol Gastroenterol Hepatol. 2021; 11(5): 1291–1311. Published online 2021 Jan 11. doi: 10.1016/j.jcmgh.2021.01.003