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Items: 1 to 20 of 54

1.
Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance
Jianglan Liu, Vito W. Rebecca, Andrew V. Kossenkov, Thomas Connelly, Qin Liu, Alexis Gutierrez, Min Xiao, Ling Li, Gao Zhang, Anastasia Samarkina, Delaine Zayasbazan, Jie Zhang, Chaoran Cheng, Zhi Wei, Gretchen M. Alicea, Mizuho Fukunaga-Kalabis, Clemens Krepler, Pedro Aza-Blanc, Chih-Cheng Yang, Bela Delvadia, Cynthia Tong, Ye Huang, Maya Delvadia, Alice S. Morias, Katrin Sproesser, Patricia Brafford, Joshua X. Wang, Marilda Beqiri, Rajasekharan Somasundaram, Adina Vultur, Denitsa M. Hristova, Lawrence W. Wu, Yiling Lu, Gordon B. Mills, Wei Xu, Giorgos C. Karakousis, Xiaowei Xu, Lynn M. Schuchter, Tara C. Mitchell, Ravi K. Amaravadi, Lawrence N. Kwong, Dennie T. Frederick, Genevieve M. Boland, Joseph M. Salvino, David W. Speicher, Keith T. Flaherty, Ze'ev A. Ronai, Meenhard Herlyn
Cancer Res. 2021 Oct 15; 81(20): 5230–5241. Published online 2021 Aug 30. doi: 10.1158/0008-5472.CAN-20-1496
PMCID:
PMC8530965
AbstractArticlePDF–14M
2.
Lysophosphatidic acid acts on LPA1 receptor to increase H2O2 during flow‐induced dilation in human adipose arterioles
Dawid S Chabowski, Andrew O Kadlec, Karima Ait‐Aissa, Joseph C Hockenberry, Paul J Pearson, Andreas M Beyer, David D Gutterman
Br J Pharmacol. 2018 Nov; 175(22): 4266–4280. Published online 2018 Oct 11. doi: 10.1111/bph.14492
PMCID:
PMC6193883
AbstractArticlePDF–860K
3.
Lys39-Lysophosphatidate Carbonyl Oxygen Interaction Locks LPA1 N-terminal Cap to the Orthosteric Site and partners Arg124 During Receptor Activation
Olaposi I. Omotuyi, Jun Nagai, Hiroshi Ueda
Sci Rep. 2015; 5: 13343. Published online 2015 Aug 13. doi: 10.1038/srep13343
PMCID:
PMC4542628
AbstractArticlePDF–1.2M
4.
Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1
Jill E. Chrencik, Christopher B. Roth, Masahiko Terakado, Haruto Kurata, Rie Omi, Yasuyuki Kihara, Dora Warshaviak, Shinji Nakade, Guillermo Asmar-Rovira, Mauro Mileni, Hirotaka Mizuno, Mark T. Griffith, Caroline Rodgers, Gye Won Han, Jeffrey Velasquez, Jerold Chun, Raymond C. Stevens, Michael A. Hanson
Cell. Author manuscript; available in PMC 2016 Jun 18.
Published in final edited form as: Cell. 2015 Jun 18; 161(7): 1633–1643. doi: 10.1016/j.cell.2015.06.002
PMCID:
PMC4476059
AbstractArticlePDF–1.8M
5.
Activation of fibroblast-like synoviocytes derived from rheumatoid arthritis via lysophosphatidic acid–lysophosphatidic acid receptor 1 cascade
Yoshishige Miyabe, Chie Miyabe, Yoshiko Iwai, Waka Yokoyama, Chiyoko Sekine, Kazutaka Sugimoto, Masayoshi Harigai, Masayuki Miyasaka, Nobuyuki Miyasaka, Toshihiro Nanki
Arthritis Res Ther. 2014; 16(5): 461. Published online 2014 Oct 2. doi: 10.1186/s13075-014-0461-9
PMCID:
PMC4203966
AbstractArticlePDF–1.2M
6.
Integrin signalling regulates the nuclear localization and function of the lysophosphatidic acid receptor-1 (LPA1) in mammalian cells
Catherine M. Waters, Bahman Saatian, Noreen A. Moughal, Yutong Zhao, Gabor Tigyi, Viswanathan Natarajan, Susan Pyne, Nigel J. Pyne
Biochem J. 2006 Aug 15; 398(Pt 1): 55–62. Prepublished online 2006 May 23. Published online 2006 Jul 27. doi: 10.1042/BJ20060155
PMCID:
PMC1525019
AbstractArticlePDF–600K
7.
LPAR1 and aberrantly expressed LPAR3 differentially promote the migration and proliferation of malignant peripheral nerve sheath tumor cells
SHANNON WEBER DOUTT, JODY FROMM LONGO, STEVEN L. CARROLL
Glia. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Glia. 2023 Mar; 71(3): 742–757. Published online 2022 Nov 23. doi: 10.1002/glia.24308
PMCID:
PMC9868101
AbstractArticlePDF–2.9M
8.
LPAR1 regulates enteric nervous system function through glial signaling and contributes to chronic intestinal pseudo-obstruction
Mohammad M. Ahmadzai, Jonathon L. McClain, Christine Dharshika, Luisa Seguella, Fiorella Giancola, Roberto De Giorgio, Brian D. Gulbransen
J Clin Invest. 2022 Feb 15; 132(4): e149464. Published online 2022 Feb 15. doi: 10.1172/JCI149464
PMCID:
PMC8843750
AbstractArticlePDF–3.6M
9.
Differential activation mechanisms of lipid GPCRs by lysophosphatidic acid and sphingosine 1-phosphate
Shian Liu, Navid Paknejad, Lan Zhu, Yasuyuki Kihara, Manisha Ray, Jerold Chun, Wei Liu, Richard K. Hite, Xin-Yun Huang
Nat Commun. 2022; 13: 731. Published online 2022 Feb 8. doi: 10.1038/s41467-022-28417-2
PMCID:
PMC8826421
AbstractArticlePDF–2.9M
10.
ATX-LPA axis facilitates estrogen-induced endometrial cancer cell proliferation via MAPK/ERK signaling pathway
Guo Zhang, Yuan Cheng, Qi Zhang, Xiaoping Li, Jingwei Zhou, Jianliu Wang, Lihui Wei
Mol Med Rep. 2018 Mar; 17(3): 4245–4252. Published online 2018 Jan 8. doi: 10.3892/mmr.2018.8392
PMCID:
PMC5802196
AbstractArticlePDF–1.7M
11.
Identification of Heparin-Binding EGF-Like Growth Factor (HB-EGF) as a Biomarker for Lysophosphatidic Acid Receptor Type 1 (LPA1) Activation in Human Breast and Prostate Cancers
Marion David, Debashish Sahay, Florence Mege, Françoise Descotes, Raphaël Leblanc, Johnny Ribeiro, Philippe Clézardin, Olivier Peyruchaud
PLoS One. 2014; 9(5): e97771. Published online 2014 May 14. doi: 10.1371/journal.pone.0097771
PMCID:
PMC4020852
AbstractArticlePDF–999K
12.
Gene Expression of the Lysophosphatidic Acid Receptor 1 Is a Target of Transforming Growth Factor Beta
Jinhua Wu, Abir Mukherjee, Deborah A Lebman, Xianjun Fang
Oncogene. Author manuscript; available in PMC 2013 Dec 27.
Published in final edited form as: Oncogene. 2013 Jun 27; 32(26): 3198–3206. Published online 2012 Jul 23. doi: 10.1038/onc.2012.325
PMCID:
PMC3480976
AbstractArticlePDF–1.1M
13.
LPA1-mediated inhibition of CXCR4 attenuates CXCL12-induced signaling and cell migration
Jong Min Hong, Jin-Woo Lee, Dong-Seung Seen, Jae-Yeon Jeong, Won-Ki Huh
Cell Commun Signal. 2023; 21: 257. Published online 2023 Sep 25. doi: 10.1186/s12964-023-01261-7
PMCID:
PMC10518940
AbstractArticlePDF–2.7M
14.
A blocking peptide stabilizes lysophosphatidic acid receptor 1 and promotes lysophosphatidic acid-induced cellular responses
Sarah J Taleb, Jianxin Wei, Rachel K Mialki, Su Dong, Yanhui Li, Jing Zhao, Yutong Zhao
J Cell Biochem. Author manuscript; available in PMC 2022 Mar 19.
Published in final edited form as: J Cell Biochem. 2021 Aug; 122(8): 827–834. Published online 2021 Apr 13. doi: 10.1002/jcb.29919
PMCID:
PMC8934197
AbstractArticlePDF–646K
15.
LPA1 Receptor Promotes Progesterone Receptor Phosphorylation through PKCα in Human Glioblastoma Cells
Silvia Anahi Valdés-Rives, Denisse Arcos-Montoya, Marisol de la Fuente-Granada, Carmen J. Zamora-Sánchez, Luis Enrique Arias-Romero, Olga Villamar-Cruz, Ignacio Camacho-Arroyo, Sonia M. Pérez-Tapia, Aliesha González-Arenas
Cells. 2021 Apr; 10(4): 807. Published online 2021 Apr 4. doi: 10.3390/cells10040807
PMCID:
PMC8066126
AbstractArticlePDF–3.1M
16.
CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model
Y Ward, R Lake, PL Martin, K Killian, P Salerno, T Wang, P Meltzer, M Merino, S-y Cheng, M Santoro, G Garcia-Rostan, K Kelly
Oncogene. Author manuscript; available in PMC 2020 Oct 15.
Published in final edited form as: Oncogene. 2013 May 30; 32(22): 2726–2738. Published online 2012 Jul 16. doi: 10.1038/onc.2012.301
PMCID:
PMC7561260
AbstractArticlePDF–4.8M
17.
The Agpat4/LPA axis in colorectal cancer cells regulates antitumor responses via p38/p65 signaling in macrophages
Dapeng Zhang, Rongchen Shi, Wei Xiang, Xia Kang, Bo Tang, Chuan Li, Linfeng Gao, Xuan Zhang, Lili Zhang, Rongyang Dai, Hongming Miao
Signal Transduct Target Ther. 2020; 5: 24. Published online 2020 Mar 27. doi: 10.1038/s41392-020-0117-y
PMCID:
PMC7099097
AbstractArticlePDF–6.3M
18.
Long noncoding RNA ZFAS1 promotes tumorigenesis and metastasis in nasopharyngeal carcinoma by sponging miR‐892b to up‐regulate LPAR1 expression
Jiaojiao Peng, Feng Liu, Hong Zheng, Qi Wu, Shixi Liu
J Cell Mol Med. 2020 Jan; 24(2): 1437–1450. Published online 2019 Dec 18. doi: 10.1111/jcmm.14823
PMCID:
PMC6991699
AbstractArticlePDF–2.0M
19.
LPA receptor heterodimerizes with CD97 to amplify LPA initiated Rho-dependent signaling and invasion in prostate cancer cells
Yvona Ward, Ross Lake, Juan Juan Yin, Christopher D. Heger, Mark Raffeld, Paul K. Goldsmith, Maria Merino, Kathleen Kelly
Cancer Res. Author manuscript; available in PMC 2019 Aug 15.
Published in final edited form as: Cancer Res. 2011 Dec 1; 71(23): 7301–7311. Published online 2011 Oct 6. doi: 10.1158/0008-5472.CAN-11-2381
PMCID:
PMC6697138
AbstractArticlePDF–2.0M
20.
ADSCs and adipocytes are the main producers in the autotaxin–lysophosphatidic acid axis of breast cancer and healthy mammary tissue in vitro
Rafael Schmid, Katharina Wolf, Jan W. Robering, Selina Strauß, Pamela L. Strissel, Reiner Strick, Matthias Rübner, Peter A. Fasching, Raymund E. Horch, Andreas E. Kremer, Anja M. Boos, Annika Weigand
BMC Cancer. 2018; 18: 1273. Published online 2018 Dec 19. doi: 10.1186/s12885-018-5166-z
PMCID:
PMC6300006
AbstractArticlePDF–1.0M

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