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Select item 14152881.

EDEM Is Involved in Retrotranslocation of Ricin from the Endoplasmic Reticulum to the Cytosol

Monika Slominska-Wojewodzka, Tone F. Gregers, Sébastien Wälchli, Kirsten Sandvig

Mol Biol Cell. 2006 Apr; 17(4): 1664–1675. doi: 10.1091/mbc.E05-10-0961

PMCID:: PMC1415288

Abstract Article PDF–566K

Select item 42065402.

Japanese encephalitis virus replication is negatively regulated by autophagy and occurs on LC3-I- and EDEM1-containing membranes

Manish Sharma, Sankar Bhattacharyya, Minu Nain, Manpreet Kaur, Vikas Sood, Vishal Gupta, Renu Khasa, Malik Z Abdin, Sudhanshu Vrati, Manjula Kalia

Autophagy. 2014 Sep 1; 10(9): 1637–1651. Published online 2014 Jul 16. doi: 10.4161/auto.29455

PMCID:: PMC4206540

Abstract Article PDF–7.2M

Select item 10838793.

A novel ER α-mannosidase-like protein accelerates ER-associated degradation

Nobuko Hosokawa, Ikuo Wada, Kiyotaka Hasegawa, Tetuya Yorihuzi, Linda O. Tremblay, Annette Herscovics, Kazuhiro Nagata

EMBO Rep. 2001 May 15; 2(5): 415–422. doi: 10.1093/embo-reports/kve084

PMCID:: PMC1083879

Abstract Article PDF–1.8M

Select item 34144984.

Tyrosinase Degradation Is Prevented when EDEM1 Lacks the Intrinsically Disordered Region

Marioara B. Marin, Simona Ghenea, Laurentiu N. Spiridon, Gabriela N. Chiritoiu, Andrei-Jose Petrescu, Stefana-Maria Petrescu

PLoS One. 2012; 7(8): e42998. Published online 2012 Aug 8. doi: 10.1371/journal.pone.0042998

PMCID:: PMC3414498

Abstract Article PDF–2.4M

Select item 5153465.

Cystic Fibrosis Transmembrane Conductance Regulator Degradation Depends on the Lectins Htm1p/EDEM and the Cdc48 Protein Complex in Yeast

Andreas Gnann, John R. Riordan, Dieter H. Wolf

Mol Biol Cell. 2004 Sep; 15(9): 4125–4135. doi: 10.1091/mbc.E04-01-0024

PMCID:: PMC515346

Abstract Article PDF–481K

Select item 35548896.

A Shared Endoplasmic Reticulum-associated Degradation Pathway Involving the EDEM1 Protein for Glycosylated and Nonglycosylated Proteins

Marina Shenkman, Bella Groisman, Efrat Ron, Edward Avezov, Linda M. Hendershot, Gerardo Z. Lederkremer

J Biol Chem. 2013 Jan 25; 288(4): 2167–2178. Published online 2012 Dec 11. doi: 10.1074/jbc.M112.438275

PMCID:: PMC3554889

Abstract Article PDF–4.9M

Select item 28595327.

Deficiency of Suppressor Enhancer Lin12 1 Like (SEL1L) in Mice Leads to Systemic Endoplasmic Reticulum Stress and Embryonic Lethality

Adam B. Francisco, Rajni Singh, Shuai Li, Anish K. Vani, Liu Yang, Robert J. Munroe, Giuseppe Diaferia, Marina Cardano, Ida Biunno, Ling Qi, John C. Schimenti, Qiaoming Long

J Biol Chem. 2010 Apr 30; 285(18): 13694–13703. Published online 2010 Mar 2. doi: 10.1074/jbc.M109.085340

PMCID:: PMC2859532

Abstract Article PDF–2.5M

Select item 33498778.

Chop (Ddit3) Is Essential for D469del-COMP Retention and Cell Death in Chondrocytes in an Inducible Transgenic Mouse Model of Pseudoachondroplasia

Karen L. Posey, Francoise Coustry, Alka C. Veerisetty, Peiman Liu, Joseph L. Alcorn, Jacqueline T. Hecht

Am J Pathol. 2012 Feb; 180(2): 727–737. doi: 10.1016/j.ajpath.2011.10.035

PMCID:: PMC3349877

Abstract Article PDF–2.5M

Select item 92505899.

Disruption of Trip11 in cranial neural crest cells is associated with increased ER and Golgi stress contributing to skull defects in mice

Hiroyuki Yamaguchi, Matthew D. Meyer, Li He, Yoshihiro Komatsu

Dev Dyn. Author manuscript; available in PMC 2023 Jul 1.

Published in final edited form as: Dev Dyn. 2022 Jul; 251(7): 1209–1222. Published online 2022 Feb 18. doi: 10.1002/dvdy.461

PMCID:: PMC9250589

Abstract Article PDF–2.3M

Select item 275784310.

Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability

Takao Iwawaki, Ryoko Akai, Shinya Yamanaka, Kenji Kohno

Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39): 16657–16662. Published online 2009 Sep 15. doi: 10.1073/pnas.0903775106

PMCID:: PMC2757843

Abstract Article PDF–2.2M

Select item 502473811.

Neuronal Rap1 regulates energy balance, glucose homeostasis, and leptin actions

Kentaro Kaneko, Pingwen Xu, Elizabeth L. Cordonier, Siyu S. Chen, Amy Ng, Yong Xu, Alexei Morozov, Makoto Fukuda

Cell Rep. Author manuscript; available in PMC 2017 Sep 13.

Published in final edited form as: Cell Rep. 2016 Sep 13; 16(11): 3003–3015. doi: 10.1016/j.celrep.2016.08.039

PMCID:: PMC5024738

Abstract Article PDF–3.1M

Select item 317940412.

Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin

Bin Zhang, Chunlei Zheng, Min Zhu, Jiayi Tao, Matthew P. Vasievich, Andrea Baines, Jinoh Kim, Randy Schekman, Randal J. Kaufman, David Ginsburg

Blood. 2011 Sep 22; 118(12): 3384–3391. Prepublished online 2011 Jul 27. doi: 10.1182/blood-2011-05-352815

PMCID:: PMC3179404

Abstract Article

Select item 461602913.

Neural tube opening and abnormal extraembryonic membrane development in SEC23A deficient mice

Min Zhu, Jiayi Tao, Matthew P. Vasievich, Wei Wei, Guojing Zhu, Rami N. Khoriaty, Bin Zhang

Sci Rep. 2015; 5: 15471. Published online 2015 Oct 23. doi: 10.1038/srep15471

PMCID:: PMC4616029

Abstract Article PDF–2.5M

Select item 340682014.

SEC23B is required for the maintenance of murine professional secretory tissues

Jiayi Tao, Min Zhu, He Wang, Solomon Afelik, Matthew P. Vasievich, Xiao-Wei Chen, Guojing Zhu, Jan Jensen, David Ginsburg, Bin Zhang

Proc Natl Acad Sci U S A. 2012 Jul 17; 109(29): E2001–E2009. Published online 2012 Jun 28. doi: 10.1073/pnas.1209207109

PMCID:: PMC3406820

Abstract Article PDF–2.6M

Select item 882106715.

CDNF and MANF regulate ER stress in a tissue-specific manner

Emmi Pakarinen, Päivi Lindholm, Mart Saarma, Maria Lindahl

Cell Mol Life Sci. 2022 Feb; 79(2): 124. Published online 2022 Feb 7. doi: 10.1007/s00018-022-04157-w

PMCID:: PMC8821067

Abstract Article PDF–5.4M

Select item 606350316.

The COPII cargo adapter SEC24C is essential for neuronal homeostasis

Bo Wang, Joung Hyuck Joo, Rebecca Mount, Brett J. W. Teubner, Alison Krenzer, Amber L. Ward, Viraj P. Ichhaporia, Elizabeth J. Adams, Rami Khoriaty, Samuel T. Peters, Shondra M. Pruett-Miller, Stanislav S. Zakharenko, David Ginsburg, Mondira Kundu

J Clin Invest. 2018 Aug 1; 128(8): 3319–3332. Published online 2018 Jun 25. doi: 10.1172/JCI98194

PMCID:: PMC6063503

Abstract Article PDF–26M

Select item 938238917.

Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism

Patrycja A Jazwiec, Violet S Patterson, Tatiane A Ribeiro, Erica Yeo, Katherine M Kennedy, Paulo C F Mathias, Jim J Petrik, Deborah M Sloboda

Biol Reprod. 2022 Aug; 107(2): 574–589. Published online 2022 Apr 4. doi: 10.1093/biolre/ioac066

PMCID:: PMC9382389

Abstract Article PDF–1.7M

Select item 509866518.

Efficient CRISPR-mediated mutagenesis in primary immune cells using CrispRGold and a C57BL/6 Cas9 transgenic mouse line

Van Trung Chu, Robin Graf, Tristan Wirtz, Timm Weber, Jeremy Favret, Xun Li, Kerstin Petsch, Ngoc Tung Tran, Michael H. Sieweke, Claudia Berek, Ralf Kühn, Klaus Rajewsky

Proc Natl Acad Sci U S A. 2016 Nov 1; 113(44): 12514–12519. Published online 2016 Oct 11. doi: 10.1073/pnas.1613884113

PMCID:: PMC5098665

Abstract Article PDF–1.5M

Select item 344473019.

D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function

Masato Sasaki, Christiane B. Knobbe, Momoe Itsumi, Andrew J. Elia, Isaac S. Harris, Iok In Christine Chio, Rob A. Cairns, Susan McCracken, Andrew Wakeham, Jillian Haight, Annick You Ten, Bryan Snow, Takeshi Ueda, Satoshi Inoue, Kazuo Yamamoto, Myunggon Ko, Anjana Rao, Katharine E. Yen, Shinsan M. Su, Tak Wah Mak

Genes Dev. 2012 Sep 15; 26(18): 2038–2049. doi: 10.1101/gad.198200.112