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Select item 78759711.

Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation

Vikas A. Tillu, James Rae, Ya Gao, Nicholas Ariotti, Matthias Floetenmeyer, Oleksiy Kovtun, Kerrie-Ann McMahon, Natasha Chaudhary, Robert G. Parton, Brett M. Collins

Nat Commun. 2021; 12: 931. Published online 2021 Feb 10. doi: 10.1038/s41467-021-21035-4

PMCID:: PMC7875971

Abstract Article PDF–20M

Select item 66156842.

Cavin-1/PTRF mediates insulin-dependent focal adhesion remodeling and ameliorates high-fat diet–induced inflammatory responses in mice

Hong Wang, Paul F. Pilch, Libin Liu

J Biol Chem. 2019 Jul 5; 294(27): 10544–10552. Published online 2019 May 24. doi: 10.1074/jbc.RA119.008824

PMCID:: PMC6615684

Abstract Article PDF–3.1M

Select item 53339633.

Muscular dystrophy in PTFR/cavin-1 null mice

Shi-Ying Ding, Libin Liu, Paul F. Pilch

JCI Insight. 2017 Mar 9; 2(5): e91023. Published online 2017 Mar 9. doi: 10.1172/jci.insight.91023

PMCID:: PMC5333963

Abstract Article PDF–1.1M

Select item 50176234.

PTRF/Cavin-1 Deficiency Causes Cardiac Dysfunction Accompanied by Cardiomyocyte Hypertrophy and Cardiac Fibrosis

Takuya Taniguchi, Naoki Maruyama, Takehiro Ogata, Takeru Kasahara, Naohiko Nakanishi, Kotaro Miyagawa, Daisuke Naito, Tetsuro Hamaoka, Masahiro Nishi, Satoaki Matoba, Tomomi Ueyama

PLoS One. 2016; 11(9): e0162513. Published online 2016 Sep 9. doi: 10.1371/journal.pone.0162513

PMCID:: PMC5017623

Abstract Article PDF–3.0M

Select item 39624025.

Arterial Dysfunction but Maintained Systemic Blood Pressure in Cavin-1-Deficient Mice

Karl Swärd, Sebastian Albinsson, Catarina Rippe

PLoS One. 2014; 9(3): e92428. Published online 2014 Mar 21. doi: 10.1371/journal.pone.0092428

PMCID:: PMC3962402

Abstract Article PDF–1.7M

Select item 39616726.

Pleiotropic Effects of Cavin-1 Deficiency on Lipid Metabolism

Shi-Ying Ding, Mi-Jeong Lee, Ross Summer, Libin Liu, Susan K. Fried, Paul F. Pilch

J Biol Chem. 2014 Mar 21; 289(12): 8473–8483. Published online 2014 Feb 7. doi: 10.1074/jbc.M113.546242

PMCID:: PMC3961672

Abstract Article PDF–2.0M

Select item 38319367.

Elevated pulmonary arterial pressure and altered expression of Ddah1 and Arg1 in mice lacking cavin-1/PTRF

Karl Swärd, Mardjaneh K Sadegh, Michiko Mori, Jonas S Erjefält, Catarina Rippe

Physiol Rep. 2013 Jun; 1(1): e00008. Published online 2013 Jun 7. doi: 10.1002/PHY2.8

PMCID:: PMC3831936

Abstract Article PDF–640K

Select item 38148348.

Suppression of PTRF Alleviates the Polymicrobial Sepsis Induced by Cecal Ligation and Puncture in Mice

Yijie Zheng, Seonjin Lee, Xiaoliang Liang, Shuquan Wei, Hyung-Geun Moon, Yang Jin

J Infect Dis. 2013 Dec 1; 208(11): 1803–1812. Published online 2013 Aug 1. doi: 10.1093/infdis/jit364

PMCID:: PMC3814834

Abstract Article PDF–713K

Select item 36362739.

Cavin1; a Regulator of Lung Function and Macrophage Phenotype

Praveen Govender, Freddy Romero, Dilip Shah, Jesus Paez, Shi-Ying Ding, Libin Liu, Adam Gower, Elizabeth Baez, Sherif Shawky Aly, Paul Pilch, Ross Summer

PLoS One. 2013; 8(4): e62045. Published online 2013 Apr 25. doi: 10.1371/journal.pone.0062045

PMCID:: PMC3636273

Abstract Article PDF–7.3M

Select item 304683610.

Polymerase I and Transcript Release Factor Regulates Lipolysis via a Phosphorylation-Dependent Mechanism

Nabila Aboulaich, Patricia C. Chui, John M. Asara, Jeffrey S. Flier, Eleftheria Maratos-Flier

Diabetes. 2011 Mar; 60(3): 757–765. Published online 2011 Feb 21. doi: 10.2337/db10-0744

PMCID:: PMC3046836

Abstract Article PDF–1.1M

Select item 258173811.

Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia and glucose intolerance

Libin Liu, Dennis Brown, Mary McKee, Nathan K. LeBrasseur, Dan Yang, Kenneth H. Albrecht, Katya Ravid, Paul F. Pilch

Cell Metab. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: Cell Metab. 2008 Oct; 8(4): 310–317. doi: 10.1016/j.cmet.2008.07.008

PMCID:: PMC2581738

Abstract Article PDF–1.4M

Select item 1077014112.

The Cavin-1/Caveolin-1 interaction attenuates BMP/Smad signaling in pulmonary hypertension by interfering with BMPR2/Caveolin-1 binding

Shinya Tomita, Naohiko Nakanishi, Takehiro Ogata, Yusuke Higuchi, Akira Sakamoto, Yumika Tsuji, Takaomi Suga, Satoaki Matoba

Commun Biol. 2024; 7: 40. Published online 2024 Jan 5. doi: 10.1038/s42003-023-05693-2

PMCID:: PMC10770141

Abstract Article PDF–2.7M

Select item 1034981313.

PTRF-IL33-ZBP1 signaling mediating macrophage necroptosis contributes to HDM-induced airway inflammation

Juan Du, Yahui Liu, Gelei Lan, Yao Zhou, Yingmeng Ni, Kai Liao, Fang Zheng, Qijian Cheng, Guochao Shi, Xiao Su

Cell Death Dis. 2023 Jul; 14(7): 432. Published online 2023 Jul 15. doi: 10.1038/s41419-023-05971-1

PMCID:: PMC10349813

Abstract Article PDF–9.6M

Select item 765518114.

Polymerase I and transcript release factor transgenic mice show impaired function of hematopoietic stem cells

Lin Bai, Ying Lyu, Guiying Shi, Keya Li, Yiying Huang, Yuanwu Ma, Yu-Sheng Cong, Lianfeng Zhang, Chuan Qin

Aging (Albany NY) 2020 Oct 31; 12(20): 20152–20162. Published online 2020 Oct 21. doi: 10.18632/aging.103729

PMCID:: PMC7655181

Abstract Article PDF–1.9M

Select item 341824515.

Co-Regulation of Cell Polarization and Migration by Caveolar Proteins PTRF/Cavin-1 and Caveolin-1

Michelle M. Hill, Noor Huda Daud, Cho Sanda Aung, Dorothy Loo, Sally Martin, Samantha Murphy, Debra M. Black, Rachael Barry, Fiona Simpson, Libin Liu, Paul F. Pilch, John F. Hancock, Marie-Odile Parat, Robert G. Parton

PLoS One. 2012; 7(8): e43041. Published online 2012 Aug 13. doi: 10.1371/journal.pone.0043041

PMCID:: PMC3418245

Abstract Article PDF–1.8M

Select item 2967516.

The transcript release factor PTRF augments ribosomal gene transcription by facilitating reinitiation of RNA polymerase I

Petr Jansa, Christof Burek, Eva E. Sander, Ingrid Grummt

Nucleic Acids Res. 2001 Jan 15; 29(2): 423–429. doi: 10.1093/nar/29.2.423

PMCID:: PMC29675

Abstract Article PDF–255K

Select item 423800617.

Caveolin-1 Expression and Cavin Stability Regulate Caveolae Dynamics in Adipocyte Lipid Store Fluctuation

Nolwenn Briand, Cécilia Prado, Guillaume Mabilleau, Françoise Lasnier, Xavier Le Lièpvre, Jeffrey D. Covington, Eric Ravussin, Soazig Le Lay, Isabelle Dugail

Diabetes. 2014 Dec; 63(12): 4032–4044. Published online 2014 Nov 13. doi: 10.2337/db13-1961

PMCID:: PMC4238006

Abstract Article PDF–2.0M

Select item 410164818.

Polymerase I and transcript release factor (PTRF) regulates adipocyte differentiation and determines adipose tissue expandability

Sergio Perez-Diaz, Lance A. Johnson, Robert M. DeKroon, Jose M. Moreno-Navarrete, Oscar Alzate, Jose M. Fernandez-Real, Nobuyo Maeda, Jose M. Arbones-Mainar

FASEB J. 2014 Aug; 28(8): 3769–3779. doi: 10.1096/fj.14-251165

PMCID:: PMC4101648

Abstract Article

Select item 329385119.

Caveolae, Fenestrae and Transendothelial Channels Retain PV1 on the Surface of Endothelial Cells

Eugene Tkachenko, Dan Tse, Olga Sideleva, Sophie J. Deharvengt, Marcus R. Luciano, Yan Xu, Caitlin L. McGarry, John Chidlow, Paul F. Pilch, William C. Sessa, Derek K. Toomre, Radu V. Stan

PLoS One. 2012; 7(3): e32655. Published online 2012 Mar 5. doi: 10.1371/journal.pone.0032655

PMCID:: PMC3293851

Abstract Article PDF–923K

Select item 271296320.

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes

Michele Bastiani, Libin Liu, Michelle M. Hill, Mark P. Jedrychowski, Susan J. Nixon, Harriet P. Lo, Daniel Abankwa, Robert Luetterforst, Manuel Fernandez-Rojo, Michael R. Breen, Steven P. Gygi, Jorgen Vinten, Piers J. Walser, Kathryn N. North, John F. Hancock, Paul F. Pilch, Robert G. Parton

J Cell Biol. 2009 Jun 29; 185(7): 1259–1273. doi: 10.1083/jcb.200903053