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Select item 99776711.

Pre‐meiotic deletion of PEX5 causes spermatogenesis failure and infertility in mice

Min Liu, Shuangyuan Liu, Chenyang Song, Haixia Zhu, Bin Wu, Aizhen Zhang, Hui Zhao, Zongzhuang Wen, Jiangang Gao

Cell Prolif. 2023 Mar; 56(3): e13365. Published online 2022 Nov 26. doi: 10.1111/cpr.13365

PMCID:: PMC9977671

Abstract Article PDF–13M

Select item 88764682.

Renal tubular peroxisomes are dispensable for normal kidney function

Camille Ansermet, Gabriel Centeno, Sylvain Pradervand, Dusan Harmacek, Andy Garcia, Jean Daraspe, Sai Kocherlakota, Myriam Baes, Yohan Bignon, Dmitri Firsov

JCI Insight. 2022 Feb 22; 7(4): e155836. Published online 2022 Feb 22. doi: 10.1172/jci.insight.155836

PMCID:: PMC8876468

Abstract Article PDF–10M

Select item 76930113.

A Novel FRET Approach Quantifies the Interaction Strength of Peroxisomal Targeting Signals and Their Receptor in Living Cells

Bernhard Hochreiter, Cheng-Shoong Chong, Andreas Hartig, Sebastian Maurer-Stroh, Johannes Berger, Johannes A. Schmid, Markus Kunze

Cells. 2020 Nov; 9(11): 2381. Published online 2020 Oct 30. doi: 10.3390/cells9112381

PMCID:: PMC7693011

Abstract Article PDF–23M

Select item 74844604.

Aging lowers PEX5 levels in cortical neurons in male and female mouse brains

Ndidi-Ese Uzor, Diego Morales Scheihing, Gab Seok Kim, Jose Felix Moruno-Manchon, Liang Zhu, Caroline R. Reynolds, Jessica M. Stephenson, Aleah Holmes, Louise D. McCullough, Andrey S. Tsvetkov

Mol Cell Neurosci. Author manuscript; available in PMC 2021 Sep 1.

Published in final edited form as: Mol Cell Neurosci. 2020 Sep; 107: 103536. Published online 2020 Aug 7. doi: 10.1016/j.mcn.2020.103536

PMCID:: PMC7484460

Abstract Article PDF–1023K

Select item 66704565.

Absence of Functional Peroxisomes from Mouse CNS Causes Dysmyelination and Axon Degeneration

Leen Hulshagen, Olga Krysko, Astrid Bottelbergs, Steven Huyghe, Rüdiger Klein, Paul P. Van Veldhoven, Peter P. De Deyn, Rudi D'Hooge, Dieter Hartmann, Myriam Baes

J Neurosci. 2008 Apr 9; 28(15): 4015–4027. doi: 10.1523/JNEUROSCI.4968-07.2008

PMCID:: PMC6670456

Abstract Article PDF–927K

Select item 45906496.

Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts

Marcus Nordgren, Tânia Francisco, Celien Lismont, Lore Hennebel, Chantal Brees, Bo Wang, Paul P Van Veldhoven, Jorge E Azevedo, Marc Fransen

Autophagy. 2015 Aug; 11(8): 1326–1340. Published online 2015 Sep 14. doi: 10.1080/15548627.2015.1061846

PMCID:: PMC4590649

Abstract Article PDF–789K

Select item 66797537.

Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes

Zhihui Zhu, Jianzhong Chen, Guanghu Wang, Ahmed Elsherbini, Liansheng Zhong, Xue Jiang, Haiyan Qin, Priyanka Tripathi, Wenbo Zhi, Stefka D. Spassieva, Andrew J. Morris, Erhard Bieberich

Biochim Biophys Acta Mol Cell Biol Lipids. Author manuscript; available in PMC 2020 Oct 1.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Oct; 1864(10): 1514–1524. Published online 2019 Jun 5. doi: 10.1016/j.bbalip.2019.05.017

PMCID:: PMC6679753

Abstract Article PDF–1.0M

Select item 34196408.

Peroxisome deficiency but not the defect in ether lipid synthesis causes activation of the innate immune system and axonal loss in the central nervous system

Astrid Bottelbergs, Simon Verheijden, Paul P Van Veldhoven, Wilhelm Just, Rita Devos, Myriam Baes

J Neuroinflammation. 2012; 9: 61. Published online 2012 Mar 29. doi: 10.1186/1742-2094-9-61

PMCID:: PMC3419640

Abstract Article PDF–4.0M

Select item 100251069.

SIRT3 improved peroxisomes-mitochondria interplay and prevented cardiac hypertrophy via preserving PEX5 expression

Minghui Wang, Yanqing Ding, Yuehuai Hu, Zeyu Li, Wenwei Luo, Peiqing Liu, Zhuoming Li

Redox Biol. 2023 Jun; 62: 102652. Published online 2023 Mar 4. doi: 10.1016/j.redox.2023.102652

PMCID:: PMC10025106

Abstract Article PDF–12M

Select item 281967110.

Alpha-Synuclein Abnormalities in Mouse Models of Peroxisome Biogenesis Disorders

Eugenia Yakunin, Ann Moser, Virginie Loeb, Ann Saada Reisch, Phyllis Faust, Denis I. Crane, Myriam Baes, Ronit Sharon

J Neurosci Res. Author manuscript; available in PMC 2010 Mar 1.

Published in final edited form as: J Neurosci Res. 2010 Mar; 88(4): 866. doi: 10.1002/jnr.22246

PMCID:: PMC2819671

Abstract Article PDF–654K

Select item 674088911.

Neuronal Migration Depends on Intact Peroxisomal Function in Brain and in Extraneuronal Tissues

Anneleen Janssen, Pierre Gressens, Markus Grabenbauer, Eveline Baumgart, Arno Schad, Ilse Vanhorebeek, Annelies Brouwers, Peter E. Declercq, Dariush Fahimi, Philippe Evrard, Luc Schoonjans, Désiré Collen, Peter Carmeliet, Guy Mannaerts, Paul Van Veldhoven, Myriam Baes

J Neurosci. 2003 Oct 29; 23(30): 9732–9741. doi: 10.1523/JNEUROSCI.23-30-09732.2003

PMCID:: PMC6740889

Abstract Article PDF–1.1M

Select item 541785012.

Peroxisomal dysfunctions cause lysosomal storage and axonal Kv1 channel redistribution in peripheral neuropathy

Sandra Kleinecke, Sarah Richert, Livia de Hoz, Britta Brügger, Theresa Kungl, Ebrahim Asadollahi, Susanne Quintes, Judith Blanz, Rhona McGonigal, Kobra Naseri, Michael W Sereda, Timo Sachsenheimer, Christian Lüchtenborg, Wiebke Möbius, Hugh Willison, Myriam Baes, Klaus-Armin Nave, Celia Michèle Kassmann

eLife. 2017; 6: e23332. Published online 2017 May 4. doi: 10.7554/eLife.23332

PMCID:: PMC5417850

Abstract Article PDF–3.3M

Select item 323494313.

Carbohydrate Metabolism Is Perturbed in Peroxisome-deficient Hepatocytes Due to Mitochondrial Dysfunction, AMP-activated Protein Kinase (AMPK) Activation, and Peroxisome Proliferator-activated Receptor γ Coactivator 1α (PGC-1α) Suppression

Annelies Peeters, Peter Fraisl, Sjoerd van den Berg, Emiel Ver Loren van Themaat, Antoine Van Kampen, Mark H. Rider, Hiroshi Takemori, Ko Willems van Dijk, Paul P. Van Veldhoven, Peter Carmeliet, Myriam Baes

J Biol Chem. 2011 Dec 9; 286(49): 42162–42179. Published online 2011 Oct 14. doi: 10.1074/jbc.M111.299727

PMCID:: PMC3234943

Abstract Article PDF–2.6M

Select item 122199414.

Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals.

L Amery, H Sano, G P Mannaerts, J Snider, J Van Looy, M Fransen, P P Van Veldhoven

Biochem J. 2001 Aug 1; 357(Pt 3): 635–646. doi: 10.1042/0264-6021:3570635

PMCID:: PMC1221994

Summary PDF–597K

Select item 322045415.

PEX5 Protein Binds Monomeric Catalase Blocking Its Tetramerization and Releases It upon Binding the N-terminal Domain of PEX14

Marta O. Freitas, Tânia Francisco, Tony A. Rodrigues, Inês S. Alencastre, Manuel P. Pinto, Cláudia P. Grou, Andreia F. Carvalho, Marc Fransen, Clara Sá-Miranda, Jorge E. Azevedo

J Biol Chem. 2011 Nov 25; 286(47): 40509–40519. Published online 2011 Oct 5. doi: 10.1074/jbc.M111.287201

PMCID:: PMC3220454

Abstract Article PDF–3.7M

Select item 185051216.

Mitochondrial Alterations Caused by Defective Peroxisomal Biogenesis in a Mouse Model for Zellweger Syndrome (PEX5 Knockout Mouse)

Eveline Baumgart, Ilse Vanhorebeek, Markus Grabenbauer, Marcel Borgers, Peter E. Declercq, H. Dariush Fahimi, Myriam Baes

Am J Pathol. 2001 Oct; 159(4): 1477–1494. doi: 10.1016/S0002-9440(10)62534-5

PMCID:: PMC1850512

Abstract Article PDF–2.2M

Select item 122161417.

Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse.

S Huyghe, M Casteels, A Janssen, L Meulders, G P Mannaerts, P E Declercq, P P Van Veldhoven, M Baes

Biochem J. 2001 Feb 1; 353(Pt 3): 673–680. doi: 10.1042/0264-6021:3530673

PMCID:: PMC1221614

Summary PDF–165K

Select item 698968618.

Spatiotemporal contact between peroxisomes and lipid droplets regulates fasting-induced lipolysis via PEX5

Jinuk Kong, Yul Ji, Yong Geun Jeon, Ji Seul Han, Kyung Hee Han, Jung Hyun Lee, Gung Lee, Hagoon Jang, Sung Sik Choe, Myriam Baes, Jae Bum Kim

Nat Commun. 2020; 11: 578. Published online 2020 Jan 29. doi: 10.1038/s41467-019-14176-0

PMCID:: PMC6989686

Abstract Article PDF–7.3M

Select item 391664919.

Novel Protein Interactions with Endoglin and Activin Receptor-like Kinase 1: Potential Role in Vascular Networks

Guoxiong Xu, Miriam Barrios-Rodiles, Mirjana Jerkic, Andrei L. Turinsky, Robert Nadon, Sonia Vera, Despina Voulgaraki, Jeffrey L. Wrana, Mourad Toporsian, Michelle Letarte

Mol Cell Proteomics. 2014 Feb; 13(2): 489–502. Published online 2013 Dec 7. doi: 10.1074/mcp.M113.033464

PMCID:: PMC3916649

Abstract Article PDF–4.1M

Select item 809881420.

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis

Shalini Menon, Dennis Goldfarb, Chris T. Ho, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, M. Ben Major, Stephanie L. Gupton

Mol Biol Cell. 2021 Feb 15; 32(4): 314–330. doi: 10.1091/mbc.E20-10-0622