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Select item 104707841.

Loss of stearoyl-CoA desaturase 2 disrupts inflammatory response in macrophages

Joseph B. Lin, Amy Mora, Tzu Jui Wang, Andrea Santeford, Darksha Usmani, Marianne M. Ligon, Indira U. Mysorekar, Rajendra S. Apte

mBio. 2023 Jul-Aug; 14(4): e00925-23. Published online 2023 Jul 7. doi: 10.1128/mbio.00925-23

PMCID:: PMC10470784

Article PDF–4.3M

Select item 101673142.

Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis

Sonal Sinha, Satoka Aizawa, Yasuhiro Nakano, Alexander Rialdi, Hye Yeon Choi, Rajan Shrestha, Stephanie Q. Pan, Yibu Chen, Meng Li, Audrey Kapelanski-Lamoureux, Gregory Yochum, Linda Sher, Satdarshan Paul Monga, Anthoula Lazaris, Keigo Machida, Michael Karin, Ernesto Guccione, Hidekazu Tsukamoto

Nat Commun. 2023; 14: 2651. Published online 2023 May 8. doi: 10.1038/s41467-023-38406-8

PMCID:: PMC10167314

Article PDF–2.9M

Select item 75936313.

Transcriptional activation of the mouse Scd2 gene by interdependent enhancers and long noncoding RNAs in ovarian granulosa cells

Shota MAYAMA, Nobuhiko HAMAZAKI, Yuki MARUYAMA, Shin MATSUBARA, Atsushi P. KIMURA

J Reprod Dev. 2020 Oct; 66(5): 435–444. Published online 2020 Jun 5. doi: 10.1262/jrd.2019-161

PMCID:: PMC7593631

Article PDF–1.4M

Select item 73106744.

Global deficiency of stearoyl-CoA desaturase-2 protects against diet-induced adiposity

Lucas M. O’Neill, Yar Xin Phang, Majaliwa Matango, Sohel Shamsuzzaman, Chang-An Guo, David W. Nelson, Chi-Liang E. Yen, James M. Ntambi

Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Jun 30.

Published in final edited form as: Biochem Biophys Res Commun. 2020 Jun 30; 527(3): 589–595. Published online 2020 May 15. doi: 10.1016/j.bbrc.2020.04.077

PMCID:: PMC7310674

Article PDF–1.0M

Select item 46657955.

Saturated phosphatidic acids mediate saturated fatty acid–induced vascular calcification and lipotoxicity

Masashi Masuda, Shinobu Miyazaki-Anzai, Audrey L. Keenan, Kayo Okamura, Jessica Kendrick, Michel Chonchol, Stefan Offermanns, James M. Ntambi, Makoto Kuro-o, Makoto Miyazaki

J Clin Invest. 2015 Dec 1; 125(12): 4544–4558. Published online 2015 Oct 26. doi: 10.1172/JCI82871

PMCID:: PMC4665795

Article PDF–2.2M

Select item 11949146.

Stearoyl-CoA desaturase-2 gene expression is required for lipid synthesis during early skin and liver development

Makoto Miyazaki, Agnieszka Dobrzyn, Peter M. Elias, James M. Ntambi

Proc Natl Acad Sci U S A. 2005 Aug 30; 102(35): 12501–12506. Published online 2005 Aug 23. doi: 10.1073/pnas.0503132102

PMCID:: PMC1194914

Article PDF–543K

Select item 76979997.

Stearoyl-CoA Desaturase-2 in Murine Development, Metabolism, and Disease

Lucas M. O’Neill, Chang-An Guo, Fang Ding, Yar Xin Phang, Zhaojin Liu, Sohel Shamsuzzaman, James M. Ntambi

Int J Mol Sci. 2020 Nov; 21(22): 8619. Published online 2020 Nov 16. doi: 10.3390/ijms21228619

PMCID:: PMC7697999

Article PDF–3.6M

Select item 38452368.

Stearoyl CoA desaturase is required to produce active, lipid-modified Wnt proteins

Jessica Rios-Esteves, Marilyn D. Resh

Cell Rep. Author manuscript; available in PMC 2014 Sep 26.

Published in final edited form as: Cell Rep. 2013 Sep 26; 4(6): 10.1016/j.celrep.2013.08.027. Published online 2013 Sep 19. doi: 10.1016/j.celrep.2013.08.027

PMCID:: PMC3845236

Article PDF–3.3M

Select item 37637749.

Susceptibility of Podocytes to Palmitic Acid Is Regulated by Stearoyl-CoA Desaturases 1 and 2

Jonas Sieber, Astrid Weins, Kapil Kampe, Stefan Gruber, Maja T. Lindenmeyer, Clemens D. Cohen, Jana M. Orellana, Peter Mundel, Andreas W. Jehle

Am J Pathol. 2013 Sep; 183(3): 735–744. doi: 10.1016/j.ajpath.2013.05.023

PMCID:: PMC3763774

Article PDF–1.3M

Select item 824202310.

SCD2-mediated monounsaturated fatty acid metabolism regulates cGAS-STING-dependent type I IFN responses in CD4⁺ T cells

Toshio Kanno, Takahiro Nakajima, Satoru Yokoyama, Hikari K. Asou, Shigemi Sasamoto, Yasuhiro Kamii, Koji Hayashizaki, Yasuo Ouchi, Taishi Onodera, Yoshimasa Takahashi, Kazutaka Ikeda, Yoshinori Hasegawa, Yuki Kinjo, Osamu Ohara, Toshinori Nakayama, Yusuke Endo

Commun Biol. 2021; 4: 820. Published online 2021 Jun 29. doi: 10.1038/s42003-021-02310-y

PMCID:: PMC8242023

Article PDF–3.7M

Select item 3544611.

From hematopoiesis to neuropoiesis: Evidence of overlapping genetic programs

Alexey V. Terskikh, Mathew C. Easterday, Linheng Li, Leroy Hood, Harley I. Kornblum, Daniel H. Geschwind, Irving L. Weissman

Proc Natl Acad Sci U S A. 2001 Jul 3; 98(14): 7934–7939. doi: 10.1073/pnas.131200898

PMCID:: PMC35446

Article PDF–585K

Select item 789117512.

Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome

Wei-Yuan Hsieh, Quan D. Zhou, Autumn G. York, Kevin J. Williams, Philip O. Scumpia, Eliza B. Kronenberger, Xen Ping Hoi, Baolong Su, Xun Chi, Viet L. Bui, Elvira Khialeeva, Amber Kaplan, Young Min Son, Ajit S. Divakaruni, Jie Sun, Stephen T. Smale, Richard A. Flavell, Steven J. Bensinger

Cell Metab. Author manuscript; available in PMC 2021 Jul 7.

Published in final edited form as: Cell Metab. 2020 Jul 7; 32(1): 128–143.e5. Published online 2020 Jun 8. doi: 10.1016/j.cmet.2020.05.003

PMCID:: PMC7891175

Article PDF–3.2M

Select item 313826413.

Normal Fur Development and Sebum Production Depends on Fatty Acid 2-Hydroxylase Expression in Sebaceous Glands

Helena Maier, Marion Meixner, Dieter Hartmann, Roger Sandhoff, Lihua Wang-Eckhardt, Inge Zöller, Volkmar Gieselmann, Matthias Eckhardt

J Biol Chem. 2011 Jul 22; 286(29): 25922–25934. Published online 2011 May 31. doi: 10.1074/jbc.M111.231977

PMCID:: PMC3138264

Article PDF–6.6M

Select item 582402414.

PPARα-Target Gene Expression Requires TIS21^/BTG2 Gene in Liver of the C57BL/6 Mice under Fasting Condition

Allen Eugene Hong, Min Sook Ryu, Seung Jun Kim, Seung Yong Hwang, In Kyoung Lim

Mol Cells. 2018 Feb 28; 41(2): 140–149. Published online 2018 Jan 29. doi: 10.14348/molcells.2018.2257

PMCID:: PMC5824024

Article PDF–3.2M

Select item 486590115.

Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development

Bernice H. Wong, Jia Pei Chan, Amaury Cazenave-Gassiot, Rebecca W. Poh, Juat Chin Foo, Dwight L. A. Galam, Sujoy Ghosh, Long N. Nguyen, Veluchamy A. Barathi, Sia W. Yeo, Chi D. Luu, Markus R. Wenk, David L. Silver

J Biol Chem. 2016 May 13; 291(20): 10501–10514. Published online 2016 Mar 22. doi: 10.1074/jbc.M116.721340

PMCID:: PMC4865901

Article PDF–5.4M

Select item 414181916.

Cartilage-Specific Ablation of Site-1 Protease in Mice Results in the Endoplasmic Reticulum Entrapment of Type IIB Procollagen and Down-Regulation of Cholesterol and Lipid Homeostasis

Debabrata Patra, Elizabeth DeLassus, Guosheng Liang, Linda J. Sandell

PLoS One. 2014; 9(8): e105674. Published online 2014 Aug 22. doi: 10.1371/journal.pone.0105674

PMCID:: PMC4141819

Article PDF–21M

Select item 21808117.

Local regulation of fat metabolism in peripheral nerves

Mark H.G. Verheijen, Roman Chrast, Patrick Burrola, Greg Lemke

Genes Dev. 2003 Oct 1; 17(19): 2450–2464. doi: 10.1101/gad.1116203

PMCID:: PMC218081

Article PDF–701K

Select item 1619218.

A method to identify cDNAs based on localization of green fluorescent protein fusion products

Kazuhide Misawa, Tetsuya Nosaka, Sumiyo Morita, Azusa Kaneko, Tatsutoshi Nakahata, Shigetaka Asano, Toshio Kitamura

Proc Natl Acad Sci U S A. 2000 Mar 28; 97(7): 3062–3066. Published online 2000 Mar 14. doi: 10.1073/pnas.060489597

PMCID:: PMC16192

Article PDF–189K

Select item 310970919.

Ordered progression of stage-specific miRNA profiles in the mouse B2 B-cell lineage

Diana C. Spierings, Daniel McGoldrick, Ann Marie Hamilton-Easton, Geoffrey Neale, Elizabeth P. Murchison, Greg J. Hannon, Douglas R. Green, Sebo Withoff

Blood. 2011 May 19; 117(20): 5340–5349. Prepublished online 2011 Mar 14. doi: 10.1182/blood-2010-10-316034

PMCID:: PMC3109709

Article

Select item 347934320.

Placental PPARγ Regulates Spatiotemporally Diverse Genes And A Unique Metabolic Network

Tali Shalom-Barak, Xiaowen Zhang, Tianjiao Chu, W. Timothy Schaiff, Janardan K. Reddy, Jianming Xu, Yoel Sadovsky, Yaacov Barak

Dev Biol. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Dev Biol. 2012 Dec 1; 372(1): 143–155. Published online 2012 Aug 29. doi: 10.1016/j.ydbio.2012.08.021

PMCID:: PMC3479343

Article PDF–3.8M

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