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Select item 52838301.

Suppression of C9orf72 RNA repeat-induced neurotoxicity by the ALS-associated RNA-binding protein Zfp106

Barbara Celona, John von Dollen, Sarat C Vatsavayai, Risa Kashima, Jeffrey R Johnson, Amy A Tang, Akiko Hata, Bruce L Miller, Eric J Huang, Nevan J Krogan, William W Seeley, Brian L Black

eLife. 2017; 6: e19032. Published online 2017 Jan 10. doi: 10.7554/eLife.19032

PMCID:: PMC5283830

Article PDF–2.1M

Select item 43892602.

End-targeting proteomics of isolated chromatin segments of a mammalian ribosomal RNA gene promoter

Satoru Ide, Jerome Dejardin

Nat Commun. 2015 Mar 27; 6: 6674. Published online 2015 Mar 27. doi: 10.1038/ncomms7674

PMCID:: PMC4389260

Article PDF–1.4M

Select item 43993223.

Cell Autonomous Phosphoinositide 3-Kinase Activation in Oocytes Disrupts Normal Ovarian Function Through Promoting Survival and Overgrowth of Ovarian Follicles

So-Youn Kim, Katherine Ebbert, Marilia H. Cordeiro, Megan Romero, Jie Zhu, Vanida Ann Serna, Kelly A. Whelan, Teresa K. Woodruff, Takeshi Kurita

Endocrinology. 2015 Apr; 156(4): 1464–1476. Published online 2015 Jan 16. doi: 10.1210/en.2014-1926

PMCID:: PMC4399322

Article

Select item 3943744.

3BP-1, an SH3 domain binding protein, has GAP activity for Rac and inhibits growth factor-induced membrane ruffling in fibroblasts.

P Cicchetti, A J Ridley, Y Zheng, R A Cerione, D Baltimore

EMBO J. 1995 Jul 3; 14(13): 3127–3135. doi: 10.1002/j.1460-2075.1995.tb07315.x

PMCID:: PMC394374

Summary Page Browse PDF–2.4M

Select item 47061155.

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration

Peter I. Joyce, Pietro Fratta, Allison S. Landman, Philip Mcgoldrick, Henning Wackerhage, Michael Groves, Bharani Shiva Busam, Jorge Galino, Silvia Corrochano, Olga A. Beskina, Christopher Esapa, Edward Ryder, Sarah Carter, Michelle Stewart, Gemma Codner, Helen Hilton, Lydia Teboul, Jennifer Tucker, Arimantas Lionikas, Jeanne Estabel, Ramiro Ramirez-Solis, Jacqueline K. White, Sebastian Brandner, Vincent Plagnol, David L. H. Bennet, Andrey Y. Abramov, Linda Greensmith, Elizabeth M. C. Fisher, Abraham Acevedo-Arozena

Hum Mol Genet. 2016 Jan 15; 25(2): 291–307. Published online 2015 Nov 24. doi: 10.1093/hmg/ddv471

PMCID:: PMC4706115

Article PDF–1.8M

Select item 49782836.

Severe muscle wasting and denervation in mice lacking the RNA-binding protein ZFP106

Douglas M. Anderson, Jessica Cannavino, Hui Li, Kelly M. Anderson, Benjamin R. Nelson, John McAnally, Svetlana Bezprozvannaya, Yun Liu, Weichun Lin, Ning Liu, Rhonda Bassel-Duby, Eric N. Olson

Proc Natl Acad Sci U S A. 2016 Aug 2; 113(31): E4494–E4503. Published online 2016 Jul 14. doi: 10.1073/pnas.1608423113

PMCID:: PMC4978283

Article PDF–2.3M

Select item 31464657.

SHARPIN Negatively Associates with TRAF2-Mediated NFκB Activation

Yanhua Liang

PLoS One. 2011; 6(7): e21696. Published online 2011 Jul 29. doi: 10.1371/journal.pone.0021696

PMCID:: PMC3146465

Article PDF–306K

Select item 37456108.

Molecular Characterization of Mutant Mouse Strains Generated from the EUCOMM/KOMP-CSD ES Cell Resource

Edward Ryder, Diane Gleeson, Debarati Sethi, Sapna Vyas, Evelina Miklejewska, Priya Dalvi, Bishoy Habib, Ross Cook, Matthew Hardy, Kalpesh Jhaveri, Joanna Bottomley, Hannah Wardle-Jones, James N. Bussell, Richard Houghton, Jennifer Salisbury, William C. Skarnes, Sanger Mouse Genetics Project, Ramiro Ramirez-Solis

Mamm Genome. 2013; 24(7): 286–294. Published online 2013 Aug 4. doi: 10.1007/s00335-013-9467-x

PMCID:: PMC3745610

Article PDF–353K

Select item 36990639.

Evolutionarily conserved long intergenic non-coding RNAs in the eye

Debarshi Mustafi, Brian M. Kevany, Xiaodong Bai, Tadao Maeda, Jonathan E. Sears, Ahmad M. Khalil, Krzysztof Palczewski

Hum Mol Genet. 2013 Aug 1; 22(15): 2992–3002. Published online 2013 Apr 4. doi: 10.1093/hmg/ddt156

PMCID:: PMC3699063

Article PDF–636K

Select item 567693210.

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy

Meghna Kannan, Efil Bayam, Christel Wagner, Bruno Rinaldi, Perrine F. Kretz, Peggy Tilly, Marna Roos, Lara McGillewie, Séverine Bär, Shilpi Minocha, Claire Chevalier, Chrystelle Po, Sanger Mouse Genetics Project, Jamel Chelly, Jean-Louis Mandel, Renato Borgatti, Amélie Piton, Craig Kinnear, Ben Loos, David J. Adams, Yann Hérault, Stephan C. Collins, Sylvie Friant, Juliette D. Godin, Binnaz Yalcin

Proc Natl Acad Sci U S A. 2017 Oct 31; 114(44): E9308–E9317. Published online 2017 Oct 12. doi: 10.1073/pnas.1713625114

PMCID:: PMC5676932

Article PDF–3.4M

Select item 474776811.

The LMO2 oncogene regulates DNA replication in hematopoietic cells

Marie-Claude Sincennes, Magali Humbert, Benoît Grondin, Véronique Lisi, Diogo F. T. Veiga, André Haman, Christophe Cazaux, Nazar Mashtalir, EL Bachir Affar, Alain Verreault, Trang Hoang

Proc Natl Acad Sci U S A. 2016 Feb 2; 113(5): 1393–1398. Published online 2016 Jan 13. doi: 10.1073/pnas.1515071113

PMCID:: PMC4747768

Article PDF–1.0M

Select item 874425712.

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins

Mickaële Hémono, Alexandre Haller, Johana Chicher, Anne-Marie Duchêne, Richard Patryk Ngondo

BMC Biol. 2022; 20: 13. Published online 2022 Jan 10. doi: 10.1186/s12915-021-01213-y

PMCID:: PMC8744257

Article PDF–6.0M

Select item 30068413.

Transcriptome Analysis of Mouse Stem Cells and Early Embryos

Alexei A Sharov, Yulan Piao, Ryo Matoba, Dawood B Dudekula, Yong Qian, Vincent VanBuren, Geppino Falco, Patrick R Martin, Carole A Stagg, Uwem C Bassey, Yuxia Wang, Mark G Carter, Toshio Hamatani, Kazuhiro Aiba, Hidenori Akutsu, Lioudmila Sharova, Tetsuya S Tanaka, Wendy L Kimber, Toshiyuki Yoshikawa, Saied A Jaradat, Serafino Pantano, Ramaiah Nagaraja, Kenneth R Boheler, Dennis Taub, Richard J Hodes, Dan L Longo, David Schlessinger, Jonathan Keller, Emily Klotz, Garnett Kelsoe, Akihiro Umezawa, Angelo L Vescovi, Janet Rossant, Tilo Kunath, Brigid L. M Hogan, Anna Curci, Michele D'Urso, Janet Kelso, Winston Hide, Minoru S. H Ko

PLoS Biol. 2003 Dec; 1(3): e74. Published online 2003 Dec 22. doi: 10.1371/journal.pbio.0000074

PMCID:: PMC300684

Article PDF–572K

Select item 645951014.

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel

PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194

PMCID:: PMC6459510

Article PDF–5.1M

Select item 18788515.

A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome

Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz

Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100

PMCID:: PMC187885

Article PDF–287K

Select item 16551116.

BayGenomics: a resource of insertional mutations in mouse embryonic stem cells

Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin

Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064

PMCID:: PMC165511

Article PDF–217K

Select item 793877017.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 255627018.

Large-scale gene trapping in C57BL/6N mouse embryonic stem cells

Gwenn M. Hansen, Diane C. Markesich, Michael B. Burnett, Qichao Zhu, Karen M. Dionne, Lizabeth J. Richter, Richard H. Finnell, Arthur T. Sands, Brian P. Zambrowicz, Alejandro Abuin

Genome Res. 2008 Oct; 18(10): 1670–1679. doi: 10.1101/gr.078352.108

PMCID:: PMC2556270

Article PDF–493K

Select item 357241019.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Article PDF–1.1M

Select item 28355420.

Wnk1 kinase deficiency lowers blood pressure in mice: A gene-trap screen to identify potential targets for therapeutic intervention

Brian P. Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J. Richter, James Piggott, Hector BeltrandelRio, Eric C. Buxton, Joel Edwards, Rick A. Finch, Carl J. Friddle, Anupma Gupta, Gwenn Hansen, Yi Hu, Wenhu Huang, Crystal Jaing, Billie Wayne Key, Jr., Peter Kipp, Buckley Kohlhauff, Zhi-Qing Ma, Diane Markesich, Robert Payne, David G. Potter, Ny Qian, Joseph Shaw, Jeff Schrick, Zheng-Zheng Shi, Mary Jean Sparks, Isaac Van Sligtenhorst, Peter Vogel, Wade Walke, Nianhua Xu, Qichao Zhu, Christophe Person, Arthur T. Sands

Proc Natl Acad Sci U S A. 2003 Nov 25; 100(24): 14109–14114. Published online 2003 Nov 10. doi: 10.1073/pnas.2336103100

Correction in:: Proc Natl Acad Sci U S A. 2004 Mar 23; 101(12): 4332.

PMCID:: PMC283554

Article PDF–481K

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