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Items: 1 to 20 of 31

1.
Disruption of Shmt1 Impairs Hippocampal Neurogenesis and Mnemonic Function in Mice
Elena V. Abarinov, Anna E. Beaudin, Martha S. Field, Cheryll A. Perry, Robert H. Allen, Sally P. Stabler, Patrick J. Stover
J Nutr. 2013 Jul; 143(7): 1028–1035. Published online 2013 May 22. doi: 10.3945/jn.113.174417
PMCID:
PMC3681542
AbstractArticlePDF–929K
2.
Shmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice
Anna E Beaudin, Elena V Abarinov, Drew M Noden, Cheryll A Perry, Stephanie Chu, Sally P Stabler, Robert H Allen, Patrick J Stover
Am J Clin Nutr. 2011 Apr; 93(4): 789–798. Published online 2011 Feb 23. doi: 10.3945/ajcn.110.002766
PMCID:
PMC3057548
AbstractArticlePDF–701K
3.
Cytoplasmic Serine Hydroxymethyltransferase Regulates the Metabolic Partitioning of Methylenetetrahydrofolate but Is Not Essential in Mice
Amanda J. MacFarlane, Xiaowen Liu, Cheryll A. Perry, Per Flodby, Robert H. Allen, Sally P. Stabler, Patrick J. Stover
J Biol Chem. 2008 Sep 19; 283(38): 25846–25853. doi: 10.1074/jbc.M802671200
PMCID:
PMC2533799
AbstractArticlePDF–337K
4.
HOXD8 suppresses renal cell carcinoma growth by upregulating SHMT1 expression
Yang Yang, Minghui Zhang, Yaxuan Zhao, Tingzhi Deng, Xiang Zhou, Hanxu Qian, Mengxuan Wang, Chuanchuan Zhang, Zhengjin Huo, Zijun Mao, Zhufeng Shao, Mengxue Liu, Chunhua Yang, Chunhua Lin, Fuyi Xu, Geng Tian, Yin Zhang
Cancer Sci. 2023 Dec; 114(12): 4583–4595. Published online 2023 Sep 26. doi: 10.1111/cas.15982
PMCID:
PMC10728000
AbstractArticlePDF–13M
5.
Nuclear Localization of de Novo Thymidylate Biosynthesis Pathway Is Required to Prevent Uracil Accumulation in DNA
Amanda J. MacFarlane, Donald D. Anderson, Per Flodby, Cheryll A. Perry, Robert H. Allen, Sally P. Stabler, Patrick J. Stover
J Biol Chem. 2011 Dec 23; 286(51): 44015–44022. Published online 2011 Nov 4. doi: 10.1074/jbc.M111.307629
PMCID:
PMC3243516
AbstractArticlePDF–1.2M
6.
Shmt1 Heterozygosity Impairs Folate-Dependent Thymidylate Synthesis Capacity and Modifies Risk of Apcmin-Mediated Intestinal Cancer Risk
Amanda J. MacFarlane, Cheryll A. Perry, Michael F. McEntee, David M. Lin, Patrick J. Stover
Cancer Res. Author manuscript; available in PMC 2012 Mar 15.
Published in final edited form as: Cancer Res. 2011 Mar 15; 71(6): 2098–2107. doi: 10.1158/0008-5472.CAN-10-1886
PMCID:
PMC3059437
AbstractArticlePDF–1.4M
7.
Nuclear Enrichment of Folate Cofactors and Methylenetetrahydrofolate Dehydrogenase 1 (MTHFD1) Protect de Novo Thymidylate Biosynthesis during Folate Deficiency
Martha S. Field, Elena Kamynina, Olufunmilayo C. Agunloye, Rebecca P. Liebenthal, Simon G. Lamarre, Margaret E. Brosnan, John T. Brosnan, Patrick J. Stover
J Biol Chem. 2014 Oct 24; 289(43): 29642–29650. Published online 2014 Sep 11. doi: 10.1074/jbc.M114.599589
PMCID:
PMC4207979
AbstractArticlePDF–1.3M
8.
Mouse Genetics Suggests Cell-Context Dependency for Myc-Regulated Metabolic Enzymes during Tumorigenesis
Lisa M. Nilsson, Tacha Zi Plym Forshell, Sara Rimpi, Christiane Kreutzer, Walter Pretsch, Georg W. Bornkamm, Jonas A. Nilsson
PLoS Genet. 2012 Mar; 8(3): e1002573. Published online 2012 Mar 15. doi: 10.1371/journal.pgen.1002573
PMCID:
PMC3305401
AbstractArticlePDF–640K
9.
SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis
Donald D. Anderson, Patrick J. Stover
PLoS One. 2009; 4(6): e5839. Published online 2009 Jun 9. doi: 10.1371/journal.pone.0005839
PMCID:
PMC2688753
AbstractArticlePDF–636K
10.
Penetrance of Craniofacial Anomalies in Mouse Models of Smith-Magenis Syndrome Is Modified by Genomic Sequence Surrounding Rai1: Not All Null Alleles Are Alike
Jiong Yan, Weimin Bi, James R. Lupski
Am J Hum Genet. 2007 Mar; 80(3): 518–525. Published online 2007 Jan 18. doi: 10.1086/512043
PMCID:
PMC1821110
AbstractArticlePDF–1.5M
11.
Liver and brain differential expression of one-carbon metabolism genes during ontogenesis
Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist
Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9
PMCID:
PMC8548596
AbstractArticlePDF–1.3M
12.
A molecular profile of a hematopoietic stem cell niche
Jason A. Hackney, Pierre Charbord, Brian P. Brunk, Christian J. Stoeckert, Ihor R. Lemischka, Kateri A. Moore
Proc Natl Acad Sci U S A. 2002 Oct 1; 99(20): 13061–13066. Published online 2002 Sep 11. doi: 10.1073/pnas.192124499
PMCID:
PMC130586
AbstractArticlePDF–520K
13.
Construction of Long-Transcript Enriched cDNA Libraries from Submicrogram Amounts of Total RNAs by a Universal PCR Amplification Method
Yulan Piao, Naomi T. Ko, Meng K. Lim, Minoru S.H. Ko
Genome Res. 2001 Sep; 11(9): 1553–1558. doi: 10.1101/gr.185501
PMCID:
PMC311119
AbstractArticlePDF–743K
14.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
15.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
16.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
17.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
18.
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome
Jens Hansen, Thomas Floss, Petra Van Sloun, Ernst-Martin Füchtbauer, Franz Vauti, Hans-Hennig Arnold, Frank Schnütgen, Wolfgang Wurst, Harald von Melchner, Patricia Ruiz
Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17): 9918–9922. Published online 2003 Aug 6. doi: 10.1073/pnas.1633296100
PMCID:
PMC187885
AbstractArticlePDF–287K
19.
GenePaint.org: an atlas of gene expression patterns in the mouse embryo
Axel Visel, Christina Thaller, Gregor Eichele
Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029
PMCID:
PMC308763
AbstractArticlePDF–253K
20.
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells
Doug Stryke, Michiko Kawamoto, Conrad C. Huang, Susan J. Johns, Leslie A. King, Courtney A. Harper, Elaine C. Meng, Roy E. Lee, Alice Yee, Larry L'Italien, Pao-Tien Chuang, Stephen G. Young, William C. Skarnes, Patricia C. Babbitt, Thomas E. Ferrin
Nucleic Acids Res. 2003 Jan 1; 31(1): 278–281. doi: 10.1093/nar/gkg064
PMCID:
PMC165511
AbstractArticlePDF–217K

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