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Items: 1 to 20 of 35

1.
Slc10a2-null mice uncover colon cancer-promoting actions of endogenous fecal bile acids
Jean-Pierre Raufman, Paul A. Dawson, Anuradha Rao, Cinthia B. Drachenberg, Jonathon Heath, Aaron C. Shang, Shien Hu, Min Zhan, James E. Polli, Kunrong Cheng
Carcinogenesis. 2015 Oct; 36(10): 1193–1200. Published online 2015 Jul 25. doi: 10.1093/carcin/bgv107
PMCID:
PMC4612337
AbstractArticlePDF–3.6M
2.
Bile Acid Flux Is Necessary for Normal Liver Regeneration
Willscott E. Naugler
PLoS One. 2014; 9(5): e97426. Published online 2014 May 19. doi: 10.1371/journal.pone.0097426
PMCID:
PMC4026228
AbstractArticlePDF–4.7M
3.
Importance of uncharged polar residues and proline in the proximal two-thirds (Pro107–Ser128) of the highly conserved region of mouse ileal Na+-dependent bile acid transporter, Slc10a2, in transport activity and cellular expression
Tohru Saeki, Kosuke Sato, Shiho Ito, Keisuke Ikeda, Ryuhei Kanamoto
BMC Physiol. 2013; 13: 4. Published online 2013 Feb 4. doi: 10.1186/1472-6793-13-4
PMCID:
PMC3570448
AbstractArticlePDF–1.1M
4.
Active enterohepatic cycling is not required for the choleretic actions of 24-norUrsodeoxycholic acid in mice
Jennifer K. Truong, Jianing Li, Qin Li, Kimberly Pachura, Anuradha Rao, Sanjeev Gumber, Claudia Daniela Fuchs, Andrew P. Feranchak, Saul J. Karpen, Michael Trauner, Paul A. Dawson
JCI Insight. 2023 Mar 22; 8(6): e149360. Published online 2023 Mar 22. doi: 10.1172/jci.insight.149360
PMCID:
PMC10070106
AbstractArticlePDF–3.1M
5.
Genetic determinants of gut microbiota composition and bile acid profiles in mice
Julia H. Kemis, Vanessa Linke, Kelsey L. Barrett, Frederick J. Boehm, Lindsay L. Traeger, Mark P. Keller, Mary E. Rabaglia, Kathryn L. Schueler, Donald S. Stapleton, Daniel M. Gatti, Gary A. Churchill, Daniel Amador-Noguez, Jason D. Russell, Brian S. Yandell, Karl W. Broman, Joshua J. Coon, Alan D. Attie, Federico E. Rey
PLoS Genet. 2019 Aug; 15(8): e1008073. Published online 2019 Aug 29. doi: 10.1371/journal.pgen.1008073
PMCID:
PMC6715156
AbstractArticlePDF–2.1M
6.
Gut microbiota inhibit Asbt-dependent intestinal bile acid reabsorption via Gata4
Carolien Out, Jay V. Patankar, Marcela Doktorova, Marije Boesjes, Trijnie Bos, Sanna de Boer, Rick Havinga, Henk Wolters, Renze Boverhof, Theo H. van Dijk, Anna Smoczek, André Bleich, Vinay Sachdev, Dagmar Kratky, Folkert Kuipers, Henkjan J. Verkade, Albert K. Groen
J Hepatol. Author manuscript; available in PMC 2017 Feb 6.
Published in final edited form as: J Hepatol. 2015 Sep; 63(3): 697–704. Published online 2015 May 27. doi: 10.1016/j.jhep.2015.04.030
PMCID:
PMC5293168
AbstractArticlePDF–1.0M
7.
Modulation of ileal apical Na+-dependent bile acid transporter ASBT by protein kinase C
Zaheer Sarwar, Fadi Annaba, Alka Dwivedi, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai
Am J Physiol Gastrointest Liver Physiol. 2009 Sep; 297(3): G532–G538. Published online 2009 Jul 1. doi: 10.1152/ajpgi.00052.2009
PMCID:
PMC2739819
AbstractArticle
8.
Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis
Vik Meadows, Corinn Marakovits, Burcin Ekser, Debjyoti Kundu, Tianhao Zhou, Konstantina Kyritsi, Linh Pham, Lixian Chen, Lindsey Kennedy, Ludovica Ceci, Nan Wu, Guido Carpino, Wenjun Zhang, Abdulkadir Isidan, Alison Meyer, Travis Owen, Eugenio Gaudio, Paolo Onori, Gianfranco Alpini, Heather Francis
Am J Physiol Gastrointest Liver Physiol. 2023 Jan 1; 324(1): G60–G77. Published online 2022 Nov 21. doi: 10.1152/ajpgi.00112.2022
PMCID:
PMC9799145
AbstractArticle
9.
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions
Alex Zaufel, Sandra M.W. van de Wiel, Lu Yin, Günter Fauler, Daphne Chien, Xinzhong Dong, John F. Gilmer, Jennifer K. Truong, Paul A. Dawson, Stan F. J. van de Graaf, Peter Fickert, Tarek Moustafa
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2021 Aug 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1; 1867(8): 166153. Published online 2021 Apr 22. doi: 10.1016/j.bbadis.2021.166153
PMCID:
PMC8177068
AbstractArticlePDF–1.5M
10.
Cholangiocyte bile salt transporters in cholesterol gallstone–susceptible and resistant inbred mouse strains
Julia J Liu, Jonathan N Glickman, Anatoliy I Masyuk, Nicholas F LaRusso
J Gastroenterol Hepatol. Author manuscript; available in PMC 2011 Nov 1.
Published in final edited form as: J Gastroenterol Hepatol. 2008 Oct; 23(10): 1596–1602. Published online 2008 Aug 20. doi: 10.1111/j.1440-1746.2008.05500.x
PMCID:
PMC3205912
AbstractArticlePDF–2.0M
11.
Apical sodium-dependent bile acid transporter upregulation is associated with necrotizing enterocolitis
Melissa D. Halpern, Jörn-Hendrik Weitkamp, Sarah K. Mount Patrick, Holly J. Dobrenen, Ludmila Khailova, Hernan Correa, Bohuslav Dvorak
Am J Physiol Gastrointest Liver Physiol. 2010 Sep; 299(3): G623–G631. Published online 2010 Jul 8. doi: 10.1152/ajpgi.00242.2010
PMCID:
PMC2950692
AbstractArticle
12.
Mouse organic solute transporter alpha deficiency alters FGF15 expression and bile acid metabolism
Tian Lan, Anuradha Rao, Jamie Haywood, Nancy D. Kock, Paul A. Dawson
J Hepatol. Author manuscript; available in PMC 2013 Aug 1.
Published in final edited form as: J Hepatol. 2012 Aug; 57(2): 359–365. Published online 2012 Apr 25. doi: 10.1016/j.jhep.2012.03.025
PMCID:
PMC3575595
AbstractArticlePDF–1.7M
13.
The organic solute transporter α-β, Ostα-Ostβ, is essential for intestinal bile acid transport and homeostasis
Anuradha Rao, Jamie Haywood, Ann L. Craddock, Martin G. Belinsky, Gary D. Kruh, Paul A. Dawson
Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10): 3891–3896. Published online 2008 Feb 21. doi: 10.1073/pnas.0712328105
PMCID:
PMC2268840
AbstractArticlePDF–1.1M
14.
The Heteromeric Organic Solute Transporter α-β, Ostα-Ostβ, Is an Ileal Basolateral Bile Acid Transporter
Paul A. Dawson, Melissa Hubbert, Jamie Haywood, Ann L. Craddock, Noa Zerangue, Whitney V. Christian, Nazzareno Ballatori
J Biol Chem. Author manuscript; available in PMC 2005 Sep 21.
Published in final edited form as: J Biol Chem. 2005 Feb 25; 280(8): 6960–6968. Published online 2004 Nov 24. doi: 10.1074/jbc.M412752200
PMCID:
PMC1224727
AbstractArticlePDF–1.9M
15.
CAR directs T cell adaptation to bile acids in the small intestine
Mei Lan Chen, Xiangsheng Huang, Hongtao Wang, Courtney Hegner, Yujin Liu, Jinsai Shang, Amber Eliason, Huitian Diao, HaJeung Park, Blake Frey, Guohui Wang, Sarah A. Mosure, Laura A. Solt, Douglas J. Kojetin, Alex Rodriguez-Palacios, Deborah A. Schady, Casey T. Weaver, Matthew E. Pipkin, David D. Moore, Mark S. Sundrud
Nature. Author manuscript; available in PMC 2022 Feb 22.
Published in final edited form as: Nature. 2021 May; 593(7857): 147–151. Published online 2021 Apr 7. doi: 10.1038/s41586-021-03421-6
PMCID:
PMC8862117
AbstractArticlePDF–4.8M
16.
The xenobiotic transporter Mdr1 enforces T cell homeostasis in the presence of intestinal bile acids
Wei Cao, Hisako Kayama, Mei Lan Chen, Amber Delmas, Amy Sun, Sang Yong Kim, Erumbi S. Rangarajan, Kelly McKevitt, Amanda P. Beck, Cody B. Jackson, Gogce Crynen, Angelos Oikonomopoulos, Precious N. Lacey, Gustavo J. Martinez, Tina Izard, Robin G. Lorenz, Alex Rodriguez-Palacios, Fabio Cominelli, Maria T. Abreu, Daniel W. Hommes, Sergei B. Koralov, Kiyoshi Takeda, Mark S. Sundrud
Immunity. Author manuscript; available in PMC 2018 Dec 19.
Published in final edited form as: Immunity. 2017 Dec 19; 47(6): 1182–1196.e10. doi: 10.1016/j.immuni.2017.11.012
Correction in:
Immunity. 2020 Mar 17; 52(3): 571.
PMCID:
PMC5741099
AbstractArticlePDF–1.6M
17.
Inhibition of ileal apical but not basolateral bile acid transport reduces atherosclerosis in apoE−/− mice
Tian Lan, Jamie Haywood, Paul A. Dawson
Atherosclerosis. Author manuscript; available in PMC 2014 Aug 1.
Published in final edited form as: Atherosclerosis. 2013 Aug; 229(2): 374–380. Published online 2013 May 28. doi: 10.1016/j.atherosclerosis.2013.05.017
PMCID:
PMC3724224
AbstractArticlePDF–1.4M
18.
The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis
Nathan J. Cherrington, Teresa E. Estrada, Harrison A. Frisk, Mark J. Canet, Rhiannon N. Hardwick, Bohuslav Dvorak, Katie Lux, Melissa D. Halpern
Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1; 304(1): G48–G56. Published online 2012 Nov 1. doi: 10.1152/ajpgi.00317.2012
PMCID:
PMC3543632
AbstractArticle
19.
Generation of mouse conditional and null alleles of the type III sodium-dependent phosphate cotransporter PiT-1
Maria H Festing, Mei Y Speer, Hsueh-Ying Yang, Cecilia M Giachelli
Genesis. Author manuscript; available in PMC 2010 Dec 1.
Published in final edited form as: Genesis. 2009 Dec; 47(12): 858–863. doi: 10.1002/dvg.20577
PMCID:
PMC2794919
AbstractArticlePDF–190K
20.
Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration
Brian J. Pepe-Mooney, Michael T. Dill, Anna Alemany, Jose Ordovas-Montanes, Yuki Matsushita, Anuradha Rao, Anushna Sen, Makoto Miyazaki, Sayeepriyadarshini Anakk, Paul A. Dawson, Noriaki Ono, Alex K. Shalek, Alexander van Oudenaarden, Fernando D. Camargo
Cell Stem Cell. Author manuscript; available in PMC 2020 Jul 3.
Published in final edited form as: Cell Stem Cell. 2019 Jul 3; 25(1): 23–38.e8. Published online 2019 May 9. doi: 10.1016/j.stem.2019.04.004
PMCID:
PMC6814390
AbstractArticlePDF–5.7M

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