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Items: 1 to 20 of 47

1.
Matrigel-based organoid culture of malignant mesothelioma reproduces cisplatin sensitivity through CTR1
Fumiya Ito, Katsuhiro Kato, Izumi Yanatori, Yuki Maeda, Toyoaki Murohara, Shinya Toyokuni
BMC Cancer. 2023; 23: 487. Published online 2023 May 31. doi: 10.1186/s12885-023-10966-4
PMCID:
PMC10230733
ArticlePDF–3.1M
2.
Oral Elesclomol Treatment Alleviates Copper Deficiency in Animal Models
Sai Yuan, Tamara Korolnek, Byung-Eun Kim
Front Cell Dev Biol. 2022; 10: 856300. Published online 2022 Apr 1. doi: 10.3389/fcell.2022.856300
PMCID:
PMC9010564
ArticlePDF–2.0M
3.
Inhibition of copper transporter 1 prevents α-synuclein pathology and alleviates nigrostriatal degeneration in AAV-based mouse model of Parkinson's disease
De-Hai Gou, Ting-Ting Huang, Wen Li, Xin-Di Gao, Caroline Haikal, Xin-He Wang, Dong-Yan Song, Xin Liang, Lin Zhu, Yong Tang, Chen Ding, Jia-Yi Li
Redox Biol. 2021 Jan; 38: 101795. Published online 2020 Nov 12. doi: 10.1016/j.redox.2020.101795
PMCID:
PMC7691620
ArticlePDF–18M
4.
Copper transporter 1 (CTR1) expression by mouse testicular germ cells, but not Sertoli cells, is essential for functional spermatogenesis
Rashin Ghaffari, Kristin R. Di Bona, Christopher L. Riley, John H. Richburg
PLoS One. 2019; 14(4): e0215522. Published online 2019 Apr 19. doi: 10.1371/journal.pone.0215522
PMCID:
PMC6474593
ArticlePDF–5.1M
5.
Copper is an endogenous modulator of neural circuit spontaneous activity
Sheel C. Dodani, Alana Firl, Jefferson Chan, Christine I. Nam, Allegra T. Aron, Carl S. Onak, Karla M. Ramos-Torres, Jaeho Paek, Corey M. Webster, Marla B. Feller, Christopher J. Chang
Proc Natl Acad Sci U S A. 2014 Nov 18; 111(46): 16280–16285. Published online 2014 Nov 5. doi: 10.1073/pnas.1409796111
PMCID:
PMC4246333
ArticlePDF–1.1M
6.
Copper influx transporter 1 is required for FGF, PDGF and EGF-induced MAPK signaling
Cheng-Yu Tsai, J. Cameron Finley, Sameh S. Ali, Hemal H. Patel, Stephen B. Howell
Biochem Pharmacol. Author manuscript; available in PMC 2013 Oct 15.
Published in final edited form as: Biochem Pharmacol. 2012 Oct 15; 84(8): 1007–1013. Published online 2012 Jul 25. doi: 10.1016/j.bcp.2012.07.014
PMCID:
PMC3464187
ArticlePDF–1.5M
7.
Vertebrate Ctr1 coordinates morphogenesis and progenitor cell fate and regulates embryonic stem cell differentiation
Tomomi Haremaki, Stuart T. Fraser, Yien-Ming Kuo, Margaret H. Baron, Daniel C. Weinstein
Proc Natl Acad Sci U S A. 2007 Jul 17; 104(29): 12029–12034. Published online 2007 Jul 9. doi: 10.1073/pnas.0701413104
PMCID:
PMC1924542
ArticlePDF–816K
8.
Essential role for mammalian copper transporter Ctr1 in copper homeostasis and embryonic development
Jaekwon Lee, Joseph R. Prohaska, Dennis J. Thiele
Proc Natl Acad Sci U S A. 2001 Jun 5; 98(12): 6842–6847. doi: 10.1073/pnas.111058698
PMCID:
PMC34440
ArticlePDF–872K
9.
Histidine phosphorylation relieves copper inhibition in the mammalian potassium channel KCa3.1
Shekhar Srivastava, Saswati Panda, Zhai Li, Stephen R Fuhs, Tony Hunter, Dennis J Thiele, Stevan R Hubbard, Edward Y Skolnik
eLife. 2016; 5: e16093. Published online 2016 Aug 19. doi: 10.7554/eLife.16093
PMCID:
PMC5005030
ArticlePDF–1.4M
10.
Cathepsin Protease Controls Copper and Cisplatin Accumulation via Cleavage of the Ctr1 Metal-binding Ectodomain
Helena Öhrvik, Brandon Logeman, Boris Turk, Thomas Reinheckel, Dennis J. Thiele
J Biol Chem. 2016 Jul 1; 291(27): 13905–13916. Published online 2016 May 3. doi: 10.1074/jbc.M116.731281
PMCID:
PMC4933151
ArticlePDF–1.4M
11.
Molecular modulation of the copper and cisplatin transport function of CTR1 and its interaction with IRS-4
Cheng-Yu Tsai, Christopher A. Larson, Roohangiz Safaei, Stephen B. Howell
Biochem Pharmacol. Author manuscript; available in PMC 2015 Feb 27.
Published in final edited form as: Biochem Pharmacol. 2014 Aug 15; 90(4): 379–387. Published online 2014 Jun 23. doi: 10.1016/j.bcp.2014.06.019
PMCID:
PMC4343213
ArticlePDF–802K
12.
The copper transporter Ctr1 contributes to cisplatin uptake by renal tubular cells during cisplatin nephrotoxicity
Navjotsingh Pabla, Robert F. Murphy, Kebin Liu, Zheng Dong
Am J Physiol Renal Physiol. 2009 Mar; 296(3): F505–F511. Published online 2009 Jan 14. doi: 10.1152/ajprenal.90545.2008
PMCID:
PMC2660190
Article
13.
Deletion of hepatic Ctr1 reveals its function in copper acquisition and compensatory mechanisms for copper homeostasis
Heejeong Kim, Hwa-Young Son, Sarah M. Bailey, Jaekwon Lee
Am J Physiol Gastrointest Liver Physiol. 2009 Feb; 296(2): G356–G364. Published online 2008 Dec 18. doi: 10.1152/ajpgi.90632.2008
PMCID:
PMC2643901
Article
14.
Uptake of the anticancer drug cisplatin mediated by the copper transporter Ctr1 in yeast and mammals
Seiko Ishida, Jaekwon Lee, Dennis J. Thiele, Ira Herskowitz
Proc Natl Acad Sci U S A. 2002 Oct 29; 99(22): 14298–14302. Published online 2002 Oct 7. doi: 10.1073/pnas.162491399
PMCID:
PMC137878
ArticlePDF–161K
15.
ATF3/SPI1/SLC31A1 Signaling Promotes Cuproptosis Induced by Advanced Glycosylation End Products in Diabetic Myocardial Injury
Shengqi Huo, Qian Wang, Wei Shi, Lulu Peng, Yue Jiang, Mengying Zhu, Junyi Guo, Dewei Peng, Moran Wang, Lintong Men, Bingyu Huang, Jiagao Lv, Li Lin
Int J Mol Sci. 2023 Jan; 24(2): 1667. Published online 2023 Jan 14. doi: 10.3390/ijms24021667
PMCID:
PMC9862315
ArticlePDF–6.6M
16.
Decreased Expression of the Slc31a1 Gene and Cytoplasmic Relocalization of Membrane CTR1 Protein in Renal Epithelial Cells: A Potent Protective Mechanism against Copper Nephrotoxicity in a Mouse Model of Menkes Disease
Olga Haberkiewicz, Paweł Lipiński, Rafał R. Starzyński, Aneta Jończy, Patrycja Kurowska, Mateusz Ogórek, Aleksandra Bednarz, Sylwia Herman, Dawid Hatala, Paweł Grzmil, Zenon Rajfur, Zbigniew Baster, Małgorzata Lenartowicz
Int J Mol Sci. 2022 Oct; 23(19): 11441. Published online 2022 Sep 28. doi: 10.3390/ijms231911441
PMCID:
PMC9570402
ArticlePDF–4.6M
17.
BRAFV600E-Driven Lung Adenocarcinoma Requires Copper to Sustain Autophagic Signaling and Processing
Tiffany Tsang, Xingxing Gu, Caroline I. Davis, Jessica M. Posimo, Zoey A. Miller, Donita C. Brady
Mol Cancer Res. 2022 Jul 6; 20(7): 1096–1107. Published online 2022 Mar 23. doi: 10.1158/1541-7786.MCR-21-0250
PMCID:
PMC9262833
ArticlePDF–1.5M
18.
Cysteine Oxidation of Copper transporter SLC31A1/CTR1, drives VEGFR2 signaling and Angiogenesis
Archita Das, Dipankar Ash, Abdelrahman Y. Fouda, Varadarajan Sudhahar, Young-Mee Kim, Yali Hou, Farlyn Z Hudson, Brian K Stansfield, Ruth B. Caldwell, Maggie McMenamin, Rodney Littlejohn, Huabo Su, Maureen R. Regan, Bradley J. Merrill, Leslie B. Poole, Jack H. Kaplan, Tohru Fukai, Masuko Ushio-Fukai
Nat Cell Biol. Author manuscript; available in PMC 2022 Jul 13.
Published in final edited form as: Nat Cell Biol. 2022 Jan; 24(1): 35–50. Published online 2022 Jan 13. doi: 10.1038/s41556-021-00822-7
PMCID:
PMC8851982
ArticlePDF–5.8M
19.
Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice
Liam M. Guthrie, Shivatheja Soma, Sai Yuan, Andres Silva, Mohammad Zulkifli, Thomas C. Snavely, Hannah Faith Greene, Elyssa Nunez, Brogan Lynch, Courtney De Ville, Vinit Shanbhag, Franklin R. Lopez, Arjun Acharya, Michael J. Petris, Byung-Eun Kim, Vishal M. Gohil, James C. Sacchettini
Science. Author manuscript; available in PMC 2020 Jun 19.
Published in final edited form as: Science. 2020 May 8; 368(6491): 620–625. doi: 10.1126/science.aaz8899
PMCID:
PMC7304446
ArticlePDF–1.5M
20.
Copper Chelation Inhibits BRAFV600E-driven Melanomagenesis and Counters Resistance to BRAFV600E and MEK1/2 Inhibitors
Donita C. Brady, Matthew S. Crowe, Danielle N. Greenberg, Christopher M. Counter
Cancer Res. Author manuscript; available in PMC 2018 Nov 15.
Published in final edited form as: Cancer Res. 2017 Nov 15; 77(22): 6240–6252. Published online 2017 Oct 6. doi: 10.1158/0008-5472.CAN-16-1190
PMCID:
PMC5690876
ArticlePDF–1.0M

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