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Select item 108973931.

Cellular reprogramming in vivo initiated by SOX4 pioneer factor activity

Takeshi Katsuda, Jonathan H. Sussman, Kenji Ito, Andrew Katznelson, Salina Yuan, Naomi Takenaka, Jinyang Li, Allyson J. Merrell, Hector Cure, Qinglan Li, Reyaz Ur Rasool, Irfan A. Asangani, Kenneth S. Zaret, Ben Z. Stanger

Nat Commun. 2024; 15: 1761. Published online 2024 Feb 26. doi: 10.1038/s41467-024-45939-z

PMCID:: PMC10897393

Article PDF–12M

Select item 3094442.

The murine Sox-4 protein is encoded on a single exon.

M W Schilham, M van Eijk, M van de Wetering, H C Clevers

Nucleic Acids Res. 1993 Apr 25; 21(8): 2009. doi: 10.1093/nar/21.8.2009

PMCID:: PMC309444

Summary Page Browse PDF–163K

Select item 103828603.

Type 2 diabetes susceptibility gene GRK5 regulates physiological pancreatic β-cell proliferation via phosphorylation of HDAC5

Shugo Sasaki, Cuilan Nian, Eric E. Xu, Daniel J. Pasula, Helena Winata, Sanya Grover, Dan S. Luciani, Francis C. Lynn

iScience. 2023 Aug 18; 26(8): 107311. Published online 2023 Jul 10. doi: 10.1016/j.isci.2023.107311

PMCID:: PMC10382860

Article PDF–2.0M

Select item 98113264.

SOX4 is a novel phenotypic regulator of endothelial cells in atherosclerosis revealed by single-cell analysis

Chak Kwong Cheng, Xiao Lin, Yujie Pu, Joyce Ka Yu Tse, Yu Wang, Cheng-Lin Zhang, Xiaoyun Cao, Chi Wai Lau, Juan Huang, Lei He, Jiang-Yun Luo, Yu-Tsung Shih, Song Wan, Chi Fai Ng, Li Wang, Ronald Ching Wan Ma, Jeng-Jiann Chiu, Ting Fung Chan, Xiao Yu Tian, Yu Huang

J Adv Res. 2023 Jan; 43: 187–203. Published online 2022 Mar 1. doi: 10.1016/j.jare.2022.02.017

PMCID:: PMC9811326

Article PDF–5.9M

Select item 90746885.

SOX4 and RELA Function as Transcriptional Partners to Regulate the Expression of TNF- Responsive Genes in Fibroblast-Like Synoviocytes

Kyle Jones, Sergio Ramirez-Perez, Sean Niu, Umesh Gangishetti, Hicham Drissi, Pallavi Bhattaram

Front Immunol. 2022; 13: 789349. Published online 2022 Apr 22. doi: 10.3389/fimmu.2022.789349

PMCID:: PMC9074688

Article PDF–4.6M

Select item 85856686.

Regulation of a progenitor gene program by SOX4 is essential for mammary tumor proliferation

M. Guy Roukens, Cynthia L. Frederiks, Danielle Seinstra, Luca Braccioli, Antoine A. Khalil, Cornelieke Pals, Simon De Neck, Laura Bornes, Evelyne Beerling, Michal Mokry, Alain de Bruin, Bart Westendorp, Jacco van Rheenen, Paul J. Coffer

Oncogene. 2021; 40(45): 6343–6353. Published online 2021 Sep 28. doi: 10.1038/s41388-021-02004-z

PMCID:: PMC8585668

Article PDF–5.8M

Select item 66723507.

Prolonged Glial Expression of Sox4 in the CNS Leads to Architectural Cerebellar Defects and Ataxia

Melanie Hoser, Stephan L. Baader, Michael R. Bösl, Alice Ihmer, Michael Wegner, Elisabeth Sock

J Neurosci. 2007 May 16; 27(20): 5495–5505. doi: 10.1523/JNEUROSCI.1384-07.2007

PMCID:: PMC6672350

Article PDF–1000K

Select item 62326788.

SOX4 Promotes ATOH1-independent Intestinal Secretory Differentiation Toward Tuft and Enteroendocrine Fates

Adam D Gracz, Leigh Ann Samsa, Matthew J Fordham, Danny C Trotier, Bailey Zwarycz, Yuan-Hung Lo, Katherine Bao, Joshua Starmer, Jesse R Raab, Noah F Shroyer, R. Lee Reinhardt, Scott T Magness

Gastroenterology. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Gastroenterology. 2018 Nov; 155(5): 1508–1523.e10. Published online 2018 Jul 25. doi: 10.1053/j.gastro.2018.07.023

PMCID:: PMC6232678

Article PDF–2.2M

Select item 62197349.

SOX4 controls invariant NKT cell differentiation by tuning TCR signaling

Nidhi Malhotra, Yilin Qi, Nicholas A. Spidale, Michela Frascoli, Bing Miu, Okhyun Cho, Katelyn Sylvia, Joonsoo Kang

J Exp Med. 2018 Nov 5; 215(11): 2887–2900. doi: 10.1084/jem.20172021

PMCID:: PMC6219734

Article PDF–2.7M

Select item 499632410.

Increased expression of the diabetes gene SOX4 reduces insulin secretion by impaired fusion pore expansion

Stephan C. Collins, Hyun Woong Do, Benoit Hastoy, Alison Hugill, Julie Adam, Margarita V. Chibalina, Juris Galvanovskis, Mahdieh Godazgar, Sheena Lee, Michelle Goldsworthy, Albert Salehi, Andrei I. Tarasov, Anders H. Rosengren, Roger Cox, Patrik Rorsman

Diabetes. Author manuscript; available in PMC 2016 Aug 24.

Published in final edited form as: Diabetes. 2016 Jul; 65(7): 1952–1961. Published online 2016 Mar 18. doi: 10.2337/db15-1489

PMCID:: PMC4996324

Article PDF–2.0M

Select item 423701011.

Mutation of Murine Sox4 Untranslated Regions Results in Partially Penetrant Perinatal Lethality

Walter Guy Wiles, IV, Zhongming Mou, Yang Du, Alyssa B. Long, Christopher D. Scharer, Birdal Bilir, Demetri D. Spyropoulos, Nancy A. Jenkins, Neal G. Copeland, W. David Martin, Carlos S. Moreno

In Vivo. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: In Vivo. 2014 Sep-Oct; 28(5): 709–718.

PMCID:: PMC4237010

Article PDF–1.1M

Select item 377649712.

Epigenetic regulation of Sox4 during palate development

Ratnam S Seelan, Partha Mukhopadhyay, Dennis R Warner, Cynthia L Webb, Michele Pisano, Robert M Greene

Epigenomics. Author manuscript; available in PMC 2014 Apr 1.

Published in final edited form as: Epigenomics. 2013 Apr; 5(2): 131–146. doi: 10.2217/epi.13.1

PMCID:: PMC3776497

Article PDF–1.7M

Select item 357812413.

Sox4 is required for the survival of pro-B cells

Baohua Sun, Saradhi Mallampati, Yun Gong, Donghai Wang, Véronique Lefebvre, Xiaoping Sun

J Immunol. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: J Immunol. 2013 Mar 1; 190(5): 2080–2089. Published online 2013 Jan 23. doi: 10.4049/jimmunol.1202736

PMCID:: PMC3578124

Article PDF–2.6M

Select item 353832714.

SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia

Parham Ramezani-Rad, Huimin Geng, Christian Hurtz, Lai N. Chan, Zhengshan Chen, Hassan Jumaa, Ari Melnick, Elisabeth Paietta, William L. Carroll, Cheryl L. Willman, Véronique Lefebvre, Markus Müschen

Blood. 2013 Jan 3; 121(1): 148–155. Prepublished online 2012 Nov 14. doi: 10.1182/blood-2012-05-428938

PMCID:: PMC3538327

Article

Select item 335687715.

SoxC Transcription Factors Are Required for Neuronal Differentiation in Adult Hippocampal Neurogenesis

Lifang Mu, Lucia Berti, Giacomo Masserdotti, Marcela Covic, Theologos M. Michaelidis, Kathrin Doberauer, Katharina Merz, Frederick Rehfeld, Anja Haslinger, Michael Wegner, Elisabeth Sock, Veronique Lefebvre, Sebastien Couillard-Despres, Ludwig Aigner, Benedikt Berninger, D. Chichung Lie

J Neurosci. 2012 Feb 29; 32(9): 3067–3080. doi: 10.1523/JNEUROSCI.4679-11.2012

PMCID:: PMC3356877

Article PDF–5.0M

Select item 320828316.

Sox4 cooperates with PU.1 haploinsufficiency in murine myeloid leukemia

Georg Aue, Yang Du, Susan M. Cleveland, Stephen B. Smith, Utpal P. Davé, Delong Liu, Marc A. Weniger, Jean Yves Metais, Nancy A. Jenkins, Neal G. Copeland, Cynthia E. Dunbar

Blood. 2011 Oct 27; 118(17): 4674–4681. Prepublished online 2011 Aug 30. doi: 10.1182/blood-2011-04-351528

PMCID:: PMC3208283

Article

Select item 41366817.

Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytes.

M van de Wetering, M Oosterwegel, K van Norren, H Clevers

EMBO J. 1993 Oct; 12(10): 3847–3854. doi: 10.1002/j.1460-2075.1993.tb06063.x

PMCID:: PMC413668

Summary Page Browse PDF–2.0M

Select item 831323318.

HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways

Ryo Miyamoto, Akinori Kanai, Hiroshi Okuda, Yosuke Komata, Satoshi Takahashi, Hirotaka Matsui, Toshiya Inaba, Akihiko Yokoyama

eLife. 2021; 10: e64148. Published online 2021 Jul 26. doi: 10.7554/eLife.64148

PMCID:: PMC8313233

Article PDF–4.4M

Select item 457784519.

The microRNA-212/132 cluster regulates B cell development by targeting Sox4

Arnav Mehta, Mati Mann, Jimmy L. Zhao, Georgi K. Marinov, Devdoot Majumdar, Yvette Garcia-Flores, Xiaomi Du, Erdem Erikci, Kamal Chowdhury, David Baltimore

J Exp Med. 2015 Sep 21; 212(10): 1679–1692. doi: 10.1084/jem.20150489

PMCID:: PMC4577845

Article PDF–2.9M

Select item 418125520.

The Sox4/Tcf7l1 axis promotes progression of BCR-ABL-positive acute lymphoblastic leukemia

Haiqing Ma, Saradhi Mallampati, Yue Lu, Baohua Sun, Enze Wang, Xiaohong Leng, Yun Gong, Haifa Shen, C. Cameron Yin, Dan Jones, Hesham M. Amin, M. James You, Patrick Zweidler-McKay, Yupo Ma, Hagop M. Kantarjian, Ralph B. Arlinghaus, Armand Glassman, Xiaoping Sun

Haematologica. 2014 Oct; 99(10): 1591–1598. doi: 10.3324/haematol.2014.104695