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Select item 105400771.

The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR⁺ CD8⁺ effector state, and its deletion improves checkpoint blockade

Susan E. McClory, Oishi Bardhan, Kelly S. Rome, Josephine R. Giles, Amy E. Baxter, Lanwei Xu, Phyllis A. Gimotty, Robert B. Faryabi, E. John Wherry, Warren S. Pear, Martha S. Jordan

Cell Rep. Author manuscript; available in PMC 2023 Sep 29.

Published in final edited form as: Cell Rep. 2023 Aug 29; 42(8): 112905. Published online 2023 Jul 31. doi: 10.1016/j.celrep.2023.112905

PMCID:: PMC10540077

Article PDF–2.6M

Select item 102906562.

TRIB1 regulates liver regeneration by antagonizing the NRF2-mediated antioxidant response

Xinyue Sun, Shuai Wang, Xiulian Miao, Sheng Zeng, Yan Guo, Anqi Zhou, Ying Chen, Yifei Chen, Fangqiao Lv, Zhiwen Fan, Yutong Wang, Yong Xu, Zilong Li

Cell Death Dis. 2023 Jun; 14(6): 372. Published online 2023 Jun 24. doi: 10.1038/s41419-023-05896-9

PMCID:: PMC10290656

Article PDF–9.4M

Select item 99951313.

Aging deteriorated liver Ischemia and reperfusion injury by suppressing Tribble’s proteins 1 mediated macrophage polarization

Qi Chen, Yating Song, Ningli Yang, Xiaoming Ai, Liyong Pu, Lianbao Kong

Bioengineered. 2022; 13(6): 14519–14533. Published online 2023 Jan 24. doi: 10.1080/21655979.2022.2090218

PMCID:: PMC9995131

Article PDF–6.5M

Select item 91312674.

TRIB1 regulates tumor growth via controlling tumor-associated macrophage phenotypes and is associated with breast cancer survival and treatment response

Taewoo Kim, Jessica Johnston, Sonia Castillo-Lluva, Francisco J. Cimas, Stephen Hamby, The Cardiogenics Consortium*, Santiago Gonzalez-Moreno, Pedro Villarejo-Campos, Alison H Goodall, Guillermo Velasco, Alberto Ocana, Munitta Muthana, Endre Kiss-Toth

Theranostics. 2022; 12(8): 3584–3600. Published online 2022 Apr 24. doi: 10.7150/thno.72192

PMCID:: PMC9131267

Article PDF–2.9M

Select item 86088455.

Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder

Xuelian Zhang, Bin Zhang, Chenyang Zhang, Guibo Sun, Xiaobo Sun

Cell Death Dis. 2021 Dec; 12(12): 1098. Published online 2021 Nov 22. doi: 10.1038/s41419-021-04389-x

PMCID:: PMC8608845

Article PDF–5.9M

Select item 72019176.

Trib1 regulates T cell differentiation during chronic infection by restraining the effector program

Kelly S. Rome, Sarah J. Stein, Makoto Kurachi, Jelena Petrovic, Gregory W. Schwartz, Ethan A. Mack, Sacha Uljon, Winona W. Wu, Anne G. DeHart, Susan E. McClory, Lanwei Xu, Phyllis A. Gimotty, Stephen C. Blacklow, Robert B. Faryabi, E. John Wherry, Martha S. Jordan, Warren S. Pear

J Exp Med. 2020 May 4; 217(5): e20190888. Published online 2020 Mar 9. doi: 10.1084/jem.20190888

PMCID:: PMC7201917

Article PDF–5.5M

Select item 70989497.

Trib1 Contributes to Recovery From Ischemia/Reperfusion-Induced Acute Kidney Injury by Regulating the Polarization of Renal Macrophages

Xiangcheng Xie, Xiu Yang, Junxia Wu, Jilin Ma, Wei Wei, Xiao Fei, Ming Wang

Front Immunol. 2020; 11: 473. Published online 2020 Mar 20. doi: 10.3389/fimmu.2020.00473

PMCID:: PMC7098949

Article PDF–1.6M

Select item 60651628.

Tribbles homolog 1 deficiency modulates function and polarization of murine bone marrow–derived macrophages

Lilli Arndt, Janine Dokas, Martin Gericke, Carl Elias Kutzner, Silvana Müller, Franziska Jeromin, Joachim Thiery, Ralph Burkhardt

J Biol Chem. 2018 Jul 20; 293(29): 11527–11536. Published online 2018 Jun 13. doi: 10.1074/jbc.RA117.000703

PMCID:: PMC6065162

Article PDF–1.3M

Select item 59831999.

Neutrophils alleviate fibrosis in the CCl₄‐induced mouse chronic liver injury model

Eiko Saijou, Yutaka Enomoto, Michitaka Matsuda, Cindy Yuet‐Yin Kok, Shizuo Akira, Minoru Tanaka, Atsushi Miyajima

Hepatol Commun. 2018 Jun; 2(6): 703–717. Published online 2018 Apr 12. doi: 10.1002/hep4.1178

PMCID:: PMC5983199

Article PDF–1.0M

Select item 553727310.

IL-4 as a Repurposed Biological Drug for Myocardial Infarction through Augmentation of Reparative Cardiac Macrophages: Proof-of-Concept Data in Mice

Yusuke Shintani, Tomoya Ito, Laura Fields, Manabu Shiraishi, Yuki Ichihara, Nobuhiko Sato, Mihai Podaru, Satoshi Kainuma, Hiroyuki Tanaka, Ken Suzuki

Sci Rep. 2017; 7: 6877. Published online 2017 Jul 31. doi: 10.1038/s41598-017-07328-z

PMCID:: PMC5537273

Article PDF–14M

Select item 488717611.

Alternatively activated macrophages determine repair of the infarcted adult murine heart

Manabu Shiraishi, Yasunori Shintani, Yusuke Shintani, Hidekazu Ishida, Rie Saba, Atsushi Yamaguchi, Hideo Adachi, Kenta Yashiro, Ken Suzuki

J Clin Invest. 2016 Jun 1; 126(6): 2151–2166. Published online 2016 May 3. doi: 10.1172/JCI85782

PMCID:: PMC4887176

Article PDF–6.2M

Select item 874927212.

Adipocyte-specific tribbles pseudokinase 1 regulates plasma adiponectin and plasma lipids in mice

Elizabeth E. Ha, Gabriella I. Quartuccia, Ruifeng Ling, Chenyi Xue, Rhoda A. Karikari, Antonio Hernandez-Ono, Krista Y. Hu, Caio V. Matias, Rami Imam, Jian Cui, Natalia S. Pellegata, Stephan Herzig, Anastasia Georgiadi, Rajesh K. Soni, Robert C. Bauer

Mol Metab. 2022 Feb; 56: 101412. Published online 2021 Dec 7. doi: 10.1016/j.molmet.2021.101412

PMCID:: PMC8749272

Article PDF–2.7M

Select item 859254113.

TRIB1 regulates LDL metabolism through CEBPα-mediated effects on the LDL receptor in hepatocytes

Katherine Quiroz-Figueroa, Cecilia Vitali, Donna M. Conlon, John S. Millar, John W. Tobias, Robert C. Bauer, Nicholas J. Hand, Daniel J. Rader

J Clin Invest. 2021 Nov 15; 131(22): e146775. Published online 2021 Nov 15. doi: 10.1172/JCI146775

PMCID:: PMC8592541

Article PDF–2.2M

Select item 772861814.

Tribbles-1 Expression and Its Function to Control Inflammatory Cytokines, Including Interleukin-8 Levels are Regulated by miRNAs in Macrophages and Prostate Cancer Cells

Chiara Niespolo, Jessica M. Johnston, Sumeet R. Deshmukh, Swapna Satam, Ziyanda Shologu, Oscar Villacanas, Ian M. Sudbery, Heather L. Wilson, Endre Kiss-Toth

Front Immunol. 2020; 11: 574046. Published online 2020 Nov 27. doi: 10.3389/fimmu.2020.574046

PMCID:: PMC7728618

Article PDF–3.2M

Select item 682185215.

Berberine decreases plasma triglyceride levels and upregulates hepatic TRIB1 in LDLR wild type mice and in LDLR deficient mice

Amar Bahadur Singh, Jingwen Liu

Sci Rep. 2019; 9: 15641. Published online 2019 Oct 30. doi: 10.1038/s41598-019-52253-y

PMCID:: PMC6821852

Article PDF–1.9M

Select item 460712916.

Tribbles-1 regulates hepatic lipogenesis through posttranscriptional regulation of C/EBPα

Robert C. Bauer, Makoto Sasaki, Daniel M. Cohen, Jian Cui, Mikhaila A. Smith, Batuhan O. Yenilmez, David J. Steger, Daniel J. Rader

J Clin Invest. 2015 Oct 1; 125(10): 3809–3818. Published online 2015 Sep 8. doi: 10.1172/JCI77095

PMCID:: PMC4607129

Article PDF–1.7M

Select item 299360017.

Trib1 is a lipid- and myocardial infarction–associated gene that regulates hepatic lipogenesis and VLDL production in mice

Ralph Burkhardt, Sue-Anne Toh, William R. Lagor, Andrew Birkeland, Michael Levin, Xiaoyu Li, Megan Robblee, Victor D. Fedorov, Masahiro Yamamoto, Takashi Satoh, Shizuo Akira, Sekar Kathiresan, Jan L. Breslow, Daniel J. Rader

J Clin Invest. 2010 Dec 1; 120(12): 4410–4414. Published online 2010 Nov 15. doi: 10.1172/JCI44213

PMCID:: PMC2993600

Article PDF–575K

Select item 797643418.

Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9

Seiko Yoshino, Takashi Yokoyama, Yoshitaka Sunami, Tomoko Takahara, Aya Nakamura, Yukari Yamazaki, Shuichi Tsutsumi, Hiroyuki Aburatani, Takuro Nakamura

Blood. 2021 Jan 7; 137(1): 75–88. Prepublished online 2020 Jul 30. doi: 10.1182/blood.2019004586