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Items: 1 to 20 of 265

1.
Identification of Novel/Rare EWSR1 Fusion Partners in Undifferentiated Mesenchymal Neoplasms
Carmen Salguero-Aranda, Elena Di Blasi, Lourdes Galán, Laura Zaldumbide, Gema Civantos, David Marcilla, Enrique de Álava, Juan Díaz-Martín
Int J Mol Sci. 2024 Feb; 25(3): 1735. Published online 2024 Feb 1. doi: 10.3390/ijms25031735
PMCID:
PMC10855420
AbstractArticlePDF–3.8M
2.
EWSR1 (Ewing Sarcoma Breakpoint Region 1) maintains centromere identity
Risa Kitagawa, Yohei Niikura, Argentina Becker, Peter J Houghton, Katsumi Kitagawa
Cell Rep. Author manuscript; available in PMC 2024 Jan 1.
Published in final edited form as: Cell Rep. 2023 Jun 27; 42(6): 112568. Published online 2023 May 25. doi: 10.1016/j.celrep.2023.112568
PMCID:
PMC10758295
AbstractArticlePDF–2.8M
3.
EWS/FLI1 Characterization, Activation, Repression, Target Genes and Therapeutic Opportunities in Ewing Sarcoma
Muhammad Yasir, Jinyoung Park, Wanjoo Chun
Int J Mol Sci. 2023 Oct; 24(20): 15173. Published online 2023 Oct 14. doi: 10.3390/ijms242015173
PMCID:
PMC10607184
AbstractArticlePDF–1.7M
4.
EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma
Iftekhar A Showpnil, Julia Selich-Anderson, Cenny Taslim, Megann A Boone, Jesse C Crow, Emily R Theisen, Stephen L Lessnick
Nucleic Acids Res. 2022 Sep 23; 50(17): 9814–9837. Published online 2022 Sep 16. doi: 10.1093/nar/gkac747
PMCID:
PMC9508825
AbstractArticlePDF–7.3M
5.
EWSR1 rearrangement in papillary thyroid microcarcinoma is related to classic morphology and the presence of small-cell phenotype
Bozidar Kovacevic, Ana Caramelo, Vesna Skuletic, Snezana Cerovic, Catarina Eloy
Bosn J Basic Med Sci. 2022 Feb; 22(1): 54–63. Published online 2021 Aug 9. doi: 10.17305/bjbms.2021.6181
PMCID:
PMC8860317
AbstractArticlePDF–2.5M
6.
Overexpression of EWSR1 (Ewing sarcoma breakpoint region 1/EWS RNA binding protein 1) predicts poor survival in patients with hepatocellular carcinoma
Weijie Jiang, Tao Wu, Xuan Shi, Jiawen Xu
Bioengineered. 2021; 12(1): 7941–7949. Published online 2021 Oct 6. doi: 10.1080/21655979.2021.1982844
PMCID:
PMC8806985
AbstractArticlePDF–1.7M
7.
EWSR1, a multifunctional protein, regulates cellular function and aging via genetic and epigenetic pathways
Junghee Lee, Phuong T. Nguyen, Hyun-Soo Shim, Seung Jae Hyeon, Hyeonjoo Im, Mi-Hyun Choi, Sooyoung Chung, Neil W Kowall, Sean Bong Lee, Hoon Ryu
Biochim Biophys Acta Mol Basis Dis. Author manuscript; available in PMC 2020 Jul 1.
Published in final edited form as: Biochim Biophys Acta Mol Basis Dis. 2019 Jul 1; 1865(7): 1938–1945. Published online 2018 Nov 24. doi: 10.1016/j.bbadis.2018.10.042
PMCID:
PMC6527469
AbstractArticlePDF–1.2M
8.
Detection of specific gene rearrangements by fluorescence in situ hybridization in 16 cases of clear cell sarcoma of soft tissue and 6 cases of clear cell sarcoma-like gastrointestinal tumor
Keiko Segawa, Shintaro Sugita, Tomoyuki Aoyama, Terufumi Kubo, Hiroko Asanuma, Taro Sugawara, Yumika Ito, Mitsuhiro Tsujiwaki, Hiromi Fujita, Makoto Emori, Tadashi Hasegawa
Diagn Pathol. 2018; 13: 73. Published online 2018 Sep 15. doi: 10.1186/s13000-018-0752-6
PMCID:
PMC6138919
AbstractArticlePDF–1.8M
9.
The RNA binding protein EWS is broadly involved in the regulation of pri-miRNA processing in mammalian cells
Huiwu Ouyang, Kai Zhang, Kristi Fox-Walsh, Yang Yang, Chen Zhang, Jie Huang, Hairi Li, Yu Zhou, Xiang-Dong Fu
Nucleic Acids Res. 2017 Dec 1; 45(21): 12481–12495. Published online 2017 Oct 9. doi: 10.1093/nar/gkx912
PMCID:
PMC5716145
AbstractArticlePDF–1.8M
10.
EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcoma
A M Katschnig, M O Kauer, R Schwentner, E M Tomazou, C N Mutz, M Linder, M Sibilia, J Alonso, D N T Aryee, H Kovar
Oncogene. 2017 Oct 26; 36(43): 5995–6005. Published online 2017 Jul 3. doi: 10.1038/onc.2017.202
PMCID:
PMC5666320
AbstractArticlePDF–3.0M
11.
Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma
Kirsten M. Johnson, Cenny Taslim, Ranajeet S. Saund, Stephen L. Lessnick
PLoS One. 2017; 12(11): e0186275. Published online 2017 Nov 1. doi: 10.1371/journal.pone.0186275
PMCID:
PMC5665490
AbstractArticlePDF–4.6M
12.
Lurbinectedin inactivates the Ewing sarcoma oncoprotein EWS-FLI1 by redistributing it within the nucleus
Matt L. Harlow, Nichole Maloney, Joseph Roland, Maria Jose Guillen Navarro, Matthew K. Easton, Susan M. Kitchen-Goosen, Elissa Boguslawski, Zachary B. Madaj, Ben K. Johnson, Megan J. Bowman, Maurizio D’Incalci, Mary E. Winn, Lisa Turner, Galen Hostetter, Carlos María Galmarini, Pablo Aviles, Patrick J. Grohar
Cancer Res. Author manuscript; available in PMC 2017 Nov 15.
Published in final edited form as: Cancer Res. 2016 Nov 15; 76(22): 6657–6668. Published online 2016 Oct 3. doi: 10.1158/0008-5472.CAN-16-0568
PMCID:
PMC5567825
AbstractArticlePDF–1005K
13.
EWSR1 regulates mitosis by dynamically influencing microtubule acetylation
Yi-Long Wang, Hui Chen, Yi-Qun Zhan, Rong-Hua Yin, Chang-Yan Li, Chang-Hui Ge, Miao Yu, Xiao-Ming Yang
Cell Cycle. 2016; 15(16): 2202–2215. Published online 2016 Jun 24. doi: 10.1080/15384101.2016.1200774
PMCID:
PMC4993540
AbstractArticlePDF–1.6M
14.
Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs
Laurie K Svoboda, Ashley Harris, Natashay J Bailey, Raphaela Schwentner, Eleni Tomazou, Cornelia von Levetzow, Brian Magnuson, Mats Ljungman, Heinrich Kovar, Elizabeth R Lawlor
Epigenetics. 2014 Dec; 9(12): 1613–1625. Published online 2015 Jan 27. doi: 10.4161/15592294.2014.988048
PMCID:
PMC4622732
AbstractArticlePDF–1.6M
15.
Detection of EWS/FLI-1 fusion in non-Ewing soft tissue tumors
IO Trancău, R Huică, M Surcel, A Munteanu, C Ursaciuc
J Med Life. 2015 Jan-Mar; 8(1): 85–89.
PMCID:
PMC4397529
AbstractArticlePDF–629K
16.
Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing
Saravana P. Selvanathan, Garrett T. Graham, Hayriye V. Erkizan, Uta Dirksen, Thanemozhi G. Natarajan, Aleksandra Dakic, Songtao Yu, Xuefeng Liu, Michelle T. Paulsen, Mats E. Ljungman, Cathy H. Wu, Elizabeth R. Lawlor, Aykut Üren, Jeffrey A. Toretsky
Proc Natl Acad Sci U S A. 2015 Mar 17; 112(11): E1307–E1316. Published online 2015 Mar 3. doi: 10.1073/pnas.1500536112
PMCID:
PMC4371969
AbstractArticlePDF–1.8M
17.
Analysis of Nuclear Export Sequence Regions of FUS-Related RNA-Binding Proteins in Essential Tremor
Oswaldo Lorenzo-Betancor, Kotaro Ogaki, Alexandra Soto-Ortolaza, Catherine Labbé, Carles Vilariño-Güell, Alex Rajput, Ali H. Rajput, Pau Pastor, Sara Ortega, Elena Lorenzo, Audrey J. Strongosky, Jay A. van Gerpen, Ryan J. Uitti, Zbigniew K. Wszolek, Owen A. Ross
PLoS One. 2014; 9(11): e111989. Published online 2014 Nov 6. doi: 10.1371/journal.pone.0111989
PMCID:
PMC4222957
AbstractArticlePDF–658K
18.
EWSR1 Binds the Hepatitis C Virus cis-Acting Replication Element and Is Required for Efficient Viral Replication
Todd E. Oakland, Kyle J. Haselton, Glenn Randall
J Virol. 2013 Jun; 87(12): 6625–6634. doi: 10.1128/JVI.01006-12
PMCID:
PMC3676111
AbstractArticlePDF–1.5M
19.
EWSR1-POU5F1 Fusion in Soft Tissue Myoepithelial Tumors. A Molecular Analysis of 66 Cases, Including Soft Tissue, Bone and Visceral Lesions, Showing Common Involvement of the EWSR1 gene
Cristina R. Antonescu, Lei Zhang, Ning-en Chang, Bruce R. Pawel, William Travis, Nora Katabi, Morris Edelman, Andrew E. Rosenberg, G. Petur Nielsen, Paola Dal Cin, Christopher D.M. Fletcher
Genes Chromosomes Cancer. Author manuscript; available in PMC 2013 Jan 9.
Published in final edited form as: Genes Chromosomes Cancer. 2010 Dec; 49(12): 1114–1124. doi: 10.1002/gcc.20819
PMCID:
PMC3540416
AbstractArticlePDF–1.5M
20.
Evaluation of Polymorphisms in EWSR1 and Risk of Ewing Sarcoma: A Report from the Childhood Cancer Survivor Study
Steven G. DuBois, Robert Goldsby, Mark Segal, Jonathan Woo, Kirsten Copren, John P. Kane, Clive R. Pullinger, Katherine K. Matthay, John Witte, Stephen L. Lessnick, Leslie L. Robison, Smita Bhatia, Louise C. Strong
Pediatr Blood Cancer. Author manuscript; available in PMC 2013 Jul 15.
Published in final edited form as: Pediatr Blood Cancer. 2012 Jul 15; 59(1): 52–56. Published online 2011 Jul 25. doi: 10.1002/pbc.23263
PMCID:
PMC3204324
AbstractArticlePDF–50K

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