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Select item 109382441.

Role of Glutaminase 2 in Promoting CD4+ T Cell Production of Interleukin-2 by Supporting Antioxidant Defense in Systemic Lupus Erythematosus

Ryo Hisada, Nobuya Yoshida, Seo Yeon K. Orite, Masataka Umeda, Catalina Burbano, Marc Scherlinger, Michihito Kono, Suzanne Krishfield, George C. Tsokos

Arthritis Rheumatol. Author manuscript; available in PMC 2024 Mar 14.

Published in final edited form as: Arthritis Rheumatol. 2022 Jul; 74(7): 1204–1210. Published online 2022 May 12. doi: 10.1002/art.42112

PMCID:: PMC10938244

Article PDF–600K

Select item 93026722.

Glutaminase 2 knockdown reduces hyperammonemia and associated lethality of urea cycle disorder mouse model

Xia Mao, Helen Chen, Allen Z. Lin, Sun Kim, Michael E. Burczynski, Erqian Na, Gabor Halasz, Mark W. Sleeman, Andrew J. Murphy, Haruka Okamoto, Xiping Cheng

J Inherit Metab Dis. 2022 May; 45(3): 470–480. Published online 2022 Feb 4. doi: 10.1002/jimd.12474

PMCID:: PMC9302672

Article PDF–3.0M

Select item 60896163.

Targeting hepatic glutaminase activity to ameliorate hyperglycemia

Russell A. Miller, Yuji Shi, Wenyun Lu, David A. Pirman, Aditi Jatkar, Matthew Blatnik, Hong Wu, César Cárdenas, Min Wan, J. Kevin Foskett, Junyoung O. Park, Yiyi Zhang, William L Holland, Joshua D. Rabinowitz, Morris J. Birnbaum

Nat Med. Author manuscript; available in PMC 2018 Sep 26.

Published in final edited form as: Nat Med. 2018 May; 24(4): 518–524. Published online 2018 Mar 26. doi: 10.1038/nm.4514

PMCID:: PMC6089616

Article PDF–1.2M

Select item 106239714.

LRH‐1 activation alleviates diabetes‐induced podocyte injury by promoting GLS2‐mediated glutaminolysis

Jijia Hu, Zongwei Zhang, Hongtu Hu, Keju Yang, Zijing Zhu, Qian Yang, Wei Liang

Cell Prolif. 2023 Nov; 56(11): e13479. Published online 2023 Apr 13. doi: 10.1111/cpr.13479

PMCID:: PMC10623971

Article PDF–6.3M

Select item 12232125.

Genomic organization and transcriptional analysis of the human l-glutaminase gene.

Cristina Pérez-Gómez, José M Matés, Pedro M Gómez-Fabre, Antonio del Castillo-Olivares, Francisco J Alonso, Javier Márquez

Biochem J. 2003 Mar 15; 370(Pt 3): 771–784. doi: 10.1042/BJ20021445

PMCID:: PMC1223212

Summary PDF–501K

Select item 33679836.

Mammalian Glutaminase Gls2 Gene Encodes Two Functional Alternative Transcripts by a Surrogate Promoter Usage Mechanism

Mercedes Martín-Rufián, Marta Tosina, José A. Campos-Sandoval, Elisa Manzanares, Carolina Lobo, J. A. Segura, Francisco J. Alonso, José M. Matés, Javier Márquez

PLoS One. 2012; 7(6): e38380. Published online 2012 Jun 5. doi: 10.1371/journal.pone.0038380

PMCID:: PMC3367983

Article PDF–2.0M

Select item 33451947.

Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B-cells

Anne Le, Andrew N. Lane, Max Hamaker, Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilio J. Rojas, Barbara S. Slusher, Haixia Zhang, Lisa J. Zimmerman, Daniel C. Liebler, Robbert J.C. Slebos, Pawel K. Lorkiewicz, Richard M. Higashi, Teresa W. M. Fan, Chi V. Dang

Cell Metab. Author manuscript; available in PMC 2013 Jan 4.

Published in final edited form as: Cell Metab. 2012 Jan 4; 15(1): 110–121. doi: 10.1016/j.cmet.2011.12.009

PMCID:: PMC3345194

Article PDF–2.6M

Select item 28677548.

Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species

Sawako Suzuki, Tomoaki Tanaka, Masha V. Poyurovsky, Hidekazu Nagano, Takafumi Mayama, Shuichi Ohkubo, Maria Lokshin, Hiroyuki Hosokawa, Toshinori Nakayama, Yutaka Suzuki, Sumio Sugano, Eiichi Sato, Toshitaka Nagao, Koutaro Yokote, Ichiro Tatsuno, Carol Prives

Proc Natl Acad Sci U S A. 2010 Apr 20; 107(16): 7461–7466. Published online 2010 Mar 29. doi: 10.1073/pnas.1002459107

PMCID:: PMC2867754

Article PDF–1.3M

Select item 47909449.

Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum

Frédéric Canal, Sara Charawi, Gisèle Grimber, Christophe Houbron, Valérie Drouet, Sabine Colnot, Benoit Terris, Catherine Cavard, Christine Perret

PLoS One. 2016; 11(3): e0150997. Published online 2016 Mar 14. doi: 10.1371/journal.pone.0150997

PMCID:: PMC4790944

Article PDF–9.9M

Select item 1036598510.

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System

Ruichen Rong, Yonglong Wei, Lin Li, Tao Wang, Hao Zhu, Guanghua Xiao, Yunguan Wang

eBioMedicine. 2023 Aug; 94: 104698. Published online 2023 Jul 13. doi: 10.1016/j.ebiom.2023.104698

PMCID:: PMC10365985

Article PDF–5.4M

Select item 849642011.

Liver homeostasis is maintained by midlobular zone 2 hepatocytes

Yonglong Wei, Yunguan G. Wang, Yuemeng Jia, Lin Li, Jung Yoon, Shuyuan Zhang, Zixi Wang, Yu Zhang, Min Zhu, Tripti Sharma, Yu-Hsuan Lin, Meng-Hsiung Hsieh, Jeffrey H. Albrecht, Phuong T. Le, Clifford J. Rosen, Tao Wang, Hao Zhu

Science. Author manuscript; available in PMC 2021 Oct 7.

Published in final edited form as: Science. 2021 Feb 26; 371(6532): eabb1625. doi: 10.1126/science.abb1625

PMCID:: PMC8496420

Article PDF–6.4M

Select item 692772312.

Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo

Boris Klimovich, Thorsten Stiewe, Oleg Timofeev

Cell Cycle. 2020; 19(1): 109–123. Published online 2019 Nov 21. doi: 10.1080/15384101.2019.1693748

PMCID:: PMC6927723

Article PDF–3.9M

Select item 947785313.

Transcriptional dynamics of murine motor neuron maturation in vivo and in vitro

Tulsi Patel, Jennifer Hammelman, Siaresh Aziz, Sumin Jang, Michael Closser, Theodore L. Michaels, Jacob A. Blum, David K. Gifford, Hynek Wichterle

Nat Commun. 2022; 13: 5427. Published online 2022 Sep 15. doi: 10.1038/s41467-022-33022-4

PMCID:: PMC9477853

Article PDF–7.4M

Select item 263408514.

The European Renal Genome Project: An Integrated Approach Towards Understanding the Genetics of Kidney Development and Disease

TE Willnow, C Antignac, AW Brändli, EI Christensen, RD Cox, D Davidson, JA Davies, O Devuyst, G Eichele, ND Hastie, PJ Verroust, A Schedl, IC Meij

Organogenesis. 2005 Apr-Jun; 2(2): 42–47. doi: 10.4161/org.2.2.2118

PMCID:: PMC2634085

Article PDF–629K

Select item 311015115.

A Systems Approach Reveals that the Myogenesis Genome Network Is Regulated by the Transcriptional Repressor RP58

Shigetoshi Yokoyama, Yoshiaki Ito, Hiroe Ueno-Kudoh, Hirohito Shimizu, Kenta Uchibe, Sonia Albini, Kazuhiko Mitsuoka, Shigeru Miyaki, Minako Kiso, Akane Nagai, Tomohiro Hikata, Tadahiro Osada, Noritsugu Fukuda, Satoshi Yamashita, Daisuke Harada, Valeria Mezzano, Masataka Kasai, Pier Lorenzo Puri, Yoshihide Hayashizaki, Haruo Okado, Megumi Hashimoto, Hiroshi Asahara

Dev Cell. Author manuscript; available in PMC 2011 Jun 7.

Published in final edited form as: Dev Cell. 2009 Dec; 17(6): 836–848. doi: 10.1016/j.devcel.2009.10.011

PMCID:: PMC3110151

Article PDF–2.0M

Select item 431955916.

A high resolution spatiotemporal atlas of gene expression of the developing mouse brain

Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones

Neuron. Author manuscript; available in PMC 2015 Jul 16.

Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033

PMCID:: PMC4319559

Article PDF–3.0M

Select item 277884417.

A mitochondrial protein compendium elucidates complex I disease biology

David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha

Cell. Author manuscript; available in PMC 2009 Nov 18.

Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016

PMCID:: PMC2778844

Article PDF–1.2M

Select item 30876318.

GenePaint.org: an atlas of gene expression patterns in the mouse embryo

Axel Visel, Christina Thaller, Gregor Eichele

Nucleic Acids Res. 2004 Jan 1; 32(Database issue): D552–D556. doi: 10.1093/nar/gkh029

PMCID:: PMC308763

Article PDF–253K

Select item 793877019.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Article PDF–2.0M

Select item 357241020.

A conditional knockout resource for the genome–wide study of mouse gene function

William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley

Nature. Author manuscript; available in PMC 2013 Feb 14.

Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163

PMCID:: PMC3572410

Article PDF–1.1M

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