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Select item 105533601.

Tumor suppressor p73 induces apoptosis of murine peritoneal cell after exposure to hydatid cyst antigens; a possibly survival mechanism of cystic echinococcosis in vivo mice model

Ehsan Ahmadpour, Adel Spotin, Ata Moghimi, Firooz Shahrivar, Farhad Jadidi-Niaragh, Farnaz Hajizadeh, Sirous Mehrani, Komeil Mazhab-Jafari

PLoS One. 2023; 18(10): e0292434. Published online 2023 Oct 5. doi: 10.1371/journal.pone.0292434

PMCID:: PMC10553360

Abstract Article PDF–1.3M

Select item 104711632.

Isoform-specific disruption of the TP73 gene reveals a critical role for TAp73γ in tumorigenesis via leptin

Xiangmudong Kong, Wensheng Yan, Wenqiang Sun, Yanhong Zhang, Hee Jung Yang, Mingyi Chen, Hongwu Chen, Ralph W de Vere White, Jin Zhang, Xinbin Chen

eLife. 2023; 12: e82115. Published online 2023 Aug 31. doi: 10.7554/eLife.82115

PMCID:: PMC10471163

Abstract Article PDF–9.7M

Select item 98342513.

TP73 Isoform-specific disruption reveals a critical role of TAp73beta in growth suppression and inflammatory response

Jin Zhang, Wenqiang Sun, Wensheng Yan, Xiangmudong Kong, Tong Shen, Kyra Laubach, Mingyi Chen, Xinbin Chen

Cell Death Dis. 2023 Jan; 14(1): 14. Published online 2023 Jan 11. doi: 10.1038/s41419-022-05529-7

PMCID:: PMC9834251

Abstract Article PDF–3.8M

Select item 74696354.

P73 C-terminus is dispensable for multiciliogenesis

Niall Buckley, Emanuele Panatta, Nobuhiro Morone, Masafumi Noguchi, Luca Scorrano, Richard A. Knight, Ivano Amelio, Gerry Melino

Cell Cycle. 2020; 19(14): 1833–1845. Published online 2020 Jun 25. doi: 10.1080/15384101.2020.1783055

PMCID:: PMC7469635

Abstract Article PDF–9.3M

Select item 62816435.

p73 regulates ependymal planar cell polarity by modulating actin and microtubule cytoskeleton

Sandra Fuertes-Alvarez, Laura Maeso-Alonso, Javier Villoch-Fernandez, Merit Wildung, Marta Martin-Lopez, Clayton Marshall, Alberto J. Villena-Cortes, Inmaculada Diez-Prieto, Jennifer A. Pietenpol, Fadel Tissir, Muriel Lizé, Margarita M. Marques, Maria C. Marin

Cell Death Dis. 2018 Dec; 9(12): 1183. Published online 2018 Dec 5. doi: 10.1038/s41419-018-1205-6

PMCID:: PMC6281643

Abstract Article PDF–6.3M

Select item 59954116.

p73 Alternative Splicing: Exploring a Biological Role for the C-Terminal Isoforms

Polina Vikhreva, Gerry Melino, Ivano Amelio

J Mol Biol. 2018 Jun 22; 430(13): 1829–1838. doi: 10.1016/j.jmb.2018.04.034

PMCID:: PMC5995411

Abstract Article

Select item 50586507.

Metabolic pathways regulated by TAp73 in response to oxidative stress

Massimiliano Agostini, Margherita Annicchiarico-Petruzzelli, Gerry Melino, Alessandro Rufini

Oncotarget. 2016 May 24; 7(21): 29881–29900. Published online 2016 Apr 22. doi: 10.18632/oncotarget.8935

PMCID:: PMC5058650

Abstract Article PDF–4.8M

Select item 49119298.

TAp73 is a central transcriptional regulator of airway multiciliogenesis

Alice Nemajerova, Daniela Kramer, Saul S. Siller, Christian Herr, Orr Shomroni, Tonatiuh Pena, Cristina Gallinas Suazo, Katharina Glaser, Merit Wildung, Henrik Steffen, Anusha Sriraman, Fabian Oberle, Magdalena Wienken, Magali Hennion, Ramon Vidal, Bettina Royen, Mihai Alevra, Detlev Schild, Robert Bals, Jürgen Dönitz, Dietmar Riedel, Stefan Bonn, Ken-Ichi Takemaru, Ute M. Moll, Muriel Lizé

Genes Dev. 2016 Jun 1; 30(11): 1300–1312. doi: 10.1101/gad.279836.116

PMCID:: PMC4911929

Abstract Article PDF–2.6M

Select item 47943989.

p73 is Required for Multiciliogenesis and Regulates the Foxj1-Associated Gene Network

Clayton B Marshall, Deborah J Mays, J Scott Beeler, Jennifer M Rosenbluth, Kelli L Boyd, Gabriela L Santos Guasch, Timothy M Shaver, Lucy J Tang, Qi Liu, Yu Shyr, Bryan J Venters, Mark A Magnuson, Jennifer A Pietenpol

Cell Rep. Author manuscript; available in PMC 2016 Mar 16.

Published in final edited form as: Cell Rep. 2016 Mar 15; 14(10): 2289–2300. Published online 2016 Mar 3. doi: 10.1016/j.celrep.2016.02.035

PMCID:: PMC4794398

Abstract Article PDF–2.9M

Select item 474175710.

p73 regulates basal and starvation-induced liver metabolism in vivo

Zhaoyue He, Massimiliano Agostini, He Liu, Gerry Melino, Hans-Uwe Simon

Oncotarget. 2015 Oct 20; 6(32): 33178–33190. Published online 2015 Sep 7. doi: 10.18632/oncotarget.5090

PMCID:: PMC4741757

Abstract Article PDF–4.1M

Select item 449535411.

p73 is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF and TGFβ signaling

R Fernandez-Alonso, M Martin-Lopez, L Gonzalez-Cano, S Garcia, F Castrillo, I Diez-Prieto, A Fernandez-Corona, M E Lorenzo-Marcos, X Li, L Claesson-Welsh, M M Marques, M C Marin

Cell Death Differ. 2015 Aug; 22(8): 1287–1299. Published online 2015 Jan 9. doi: 10.1038/cdd.2014.214

PMCID:: PMC4495354

Abstract Article PDF–2.5M

Select item 397174112.

TAp73 is essential for germ cell adhesion and maturation in testis

Lena Holembowski, Daniela Kramer, Dietmar Riedel, Raffaella Sordella, Alice Nemajerova, Matthias Dobbelstein, Ute M. Moll

J Cell Biol. 2014 Mar 31; 204(7): 1173–1190. doi: 10.1083/jcb.201306066

PMCID:: PMC3971741

Abstract Article PDF–6.8M

Select item 377031713.

p73 regulates autophagy and hepatocellular lipid metabolism through a transcriptional activation of the ATG5 gene

Z He, H Liu, M Agostini, S Yousefi, A Perren, M P Tschan, T W Mak, G Melino, H U Simon

Cell Death Differ. 2013 Oct; 20(10): 1415–1424. Published online 2013 Aug 2. doi: 10.1038/cdd.2013.104

PMCID:: PMC3770317

Abstract Article PDF–2.8M

Select item 355433314.

TAp73 is required for macrophage-mediated innate immunity and the resolution of inflammatory responses

R Tomasini, V Secq, L Pouyet, A K Thakur, M Wilhelm, J Nigri, S Vasseur, P Berthezene, E Calvo, G Melino, T W Mak, J L Iovanna

Cell Death Differ. 2013 Feb; 20(2): 293–301. Published online 2012 Sep 14. doi: 10.1038/cdd.2012.123

PMCID:: PMC3554333

Abstract Article PDF–661K

Select item 355432915.

p73 is dispensable for commitment to neural stem cell fate, but is essential for neural stem cell maintenance and for blocking premature differentiation

E M Alexandrova, F Talos, U M Moll

Cell Death Differ. 2013 Feb; 20(2): 368. Published online 2012 Oct 26. doi: 10.1038/cdd.2012.134

PMCID:: PMC3554329

Article PDF–74K

Select item 326088016.

p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis

F Talos, A Abraham, AV Vaseva, L Holembowski, SE Tsirka, A Scheel, D Bode, M Dobbelstein, W Brück, UM Moll

Cell Death Differ. Author manuscript; available in PMC 2012 Jan 18.

Published in final edited form as: Cell Death Differ. 2010 Dec; 17(12): 1816–1829. doi: 10.1038/cdd.2010.131

PMCID:: PMC3260880

Abstract Article PDF–1.5M

Select item 323483817.

Complex Regulation of p73 Isoforms after Alteration of Amyloid Precursor Polypeptide (APP) Function and DNA Damage in Neurons

Samir Benosman, Xiangjun Meng, Yannick Von Grabowiecki, Lavinia Palamiuc, Lucian Hritcu, Isabelle Gross, Georg Mellitzer, Yoichi Taya, Jean-Philippe Loeffler, Christian Gaiddon

J Biol Chem. 2011 Dec 16; 286(50): 43013–43025. Published online 2011 Oct 14. doi: 10.1074/jbc.M111.261271

PMCID:: PMC3234838

Abstract Article PDF–2.0M

Select item 303229518.

p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53

L Gonzalez-Cano, M Herreros-Villanueva, R Fernandez-Alonso, A Ayuso-Sacido, G Meyer, J M Garcia-Verdugo, A Silva, M M Marques, M C Marin

Cell Death Dis. 2010 Dec; 1(12): e109. Published online 2010 Dec 16. doi: 10.1038/cddis.2010.87

PMCID:: PMC3032295

Abstract Article PDF–981K

Select item 255990319.

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

Richard Tomasini, Katsuya Tsuchihara, Margareta Wilhelm, Masashi Fujitani, Alessandro Rufini, Carol C. Cheung, Fatima Khan, Annick Itie-Youten, Andrew Wakeham, Ming-sound Tsao, Juan L. Iovanna, Jeremy Squire, Igor Jurisica, David Kaplan, Gerry Melino, Andrea Jurisicova, Tak W. Mak

Genes Dev. 2008 Oct 1; 22(19): 2677–2691. doi: 10.1101/gad.1695308