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Select item 108298311.

Tribbles pseudokinase 3 promotes enterovirus A71 infection via dual mechanisms

Huiqiang Wang, Ke Li, Boming Cui, Haiyan Yan, Shuo Wu, Kun Wang, Ge Yang, Jiandong Jiang, Yuhuan Li

Emerg Microbes Infect. 2024; 13(1): 2307514. Published online 2024 Jan 19. doi: 10.1080/22221751.2024.2307514

PMCID:: PMC10829831

Abstract Article PDF–4.2M

Select item 106636842.

The pseudokinase TRIB3 controls adipocyte lipid homeostasis and proliferation in vitro and in vivo

Miguel Hernández-Quiles, Laura Martinez Campesino, Imogen Morris, Zabran Ilyas, Steve Reynolds, Nguan Soon Tan, Paula Sobrevals Alcaraz, Edwin C.A. Stigter, Ákos Varga, János Varga, Robert van Es, Harmjan Vos, Heather L. Wilson, Endre Kiss-Toth, Eric Kalkhoven

Mol Metab. 2023 Dec; 78: 101829. Published online 2023 Oct 30. doi: 10.1016/j.molmet.2023.101829

PMCID:: PMC10663684

Abstract Article PDF–3.5M

Select item 83856183.

Tribbles Homolog 3 Mediates the Development and Progression of Diabetic Retinopathy

Priyamvada M. Pitale, Irina V. Saltykova, Yvonne Adu-Agyeiwaah, Sergio Li Calzi, Takashi Satoh, Shizuo Akira, Oleg Gorbatyuk, Michael E. Boulton, Machelle T. Pardue, W. Timothy Garvey, Mohammad Athar, Maria B. Grant, Marina S. Gorbatyuk

Diabetes. 2021 Aug; 70(8): 1738–1753. Published online 2021 May 11. doi: 10.2337/db20-1268

PMCID:: PMC8385618

Abstract Article PDF–4.7M

Select item 79820544.

Obesity-induced TRB3 Negatively Regulates Brown Adipose Tissue Function in Mice

Ha-Won Jeong, Ran Hee Choi, Ho-Jin Koh

Biochem Biophys Res Commun. Author manuscript; available in PMC 2022 Apr 2.

Published in final edited form as: Biochem Biophys Res Commun. 2021 Apr 2; 547: 29–35. Published online 2021 Feb 13. doi: 10.1016/j.bbrc.2021.01.103

PMCID:: PMC7982054

Abstract Article PDF–966K

Select item 69478545.

Effect of the alteration of Tribbles homologue 3 expression on epithelial-mesenchymal transition of transforming growth factor β1-induced mouse alveolar epithelial cells through the Wnt/β-catenin signaling pathway

Wencheng Yu, Liyun Mi, Feifei Wang

Mol Med Rep. 2020 Feb; 21(2): 615–622. Published online 2019 Dec 5. doi: 10.3892/mmr.2019.10863

PMCID:: PMC6947854

Abstract Article PDF–752K

Select item 64366546.

TRB3 regulates skeletal muscle mass in food deprivation–induced atrophy

Ran Hee Choi, Abigail McConahay, João G. Silvestre, Anselmo S. Moriscot, James A. Carson, Ho-Jin Koh

FASEB J. 2019 Apr; 33(4): 5654–5666. Published online 2019 Jan 25. doi: 10.1096/fj.201802145RR

PMCID:: PMC6436654

Abstract Article

Select item 56750107.

Tribbles 3 Regulates Protein Turnover in Mouse Skeletal Muscle

Ran Hee Choi, Abigail McConahay, Ha-Won Jeong, Jamie L. McClellan, Justin P. Hardee, James A. Carson, Michael F. Hirshman, Laurie J. Goodyear, Ho-Jin Koh

Biochem Biophys Res Commun. Author manuscript; available in PMC 2018 Nov 25.

Published in final edited form as: Biochem Biophys Res Commun. 2017 Nov 25; 493(3): 1236–1242. Published online 2017 Sep 27. doi: 10.1016/j.bbrc.2017.09.134

PMCID:: PMC5675010

Abstract Article PDF–1.2M

Select item 53939438.

Governing Roles for Trib3 Pseudokinase During Stress Erythropoiesis

Arvind Dev, Ruth Asch, Edward Jachimowicz, Nicole Rainville, Ashley Johnson, Emily Greenfest-Allen, Don M Wojchowski

Exp Hematol. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: Exp Hematol. 2017 May; 49: 48–55.e5. Published online 2017 Jan 4. doi: 10.1016/j.exphem.2016.12.010

PMCID:: PMC5393943

Abstract Article PDF–1.1M

Select item 51090399.

MicroRNA-124 promotes hepatic triglyceride accumulation through targeting tribbles homolog 3

Xing Liu, Jiejie Zhao, Qi Liu, Xuelian Xiong, Zhijian Zhang, Yang Jiao, Xiaoying Li, Bin Liu, Yao Li, Yan Lu

Sci Rep. 2016; 6: 37170. Published online 2016 Nov 15. doi: 10.1038/srep37170

PMCID:: PMC5109039

Abstract Article PDF–1.5M

Select item 495599010.

Skeletal Muscle TRIB3 Mediates Glucose Toxicity in Diabetes and High- Fat Diet–Induced Insulin Resistance

Wei Zhang, Mengrui Wu, Teayoun Kim, Ravi H. Jariwala, W. John Garvey, Nanlan Luo, Minsung Kang, Elizabeth Ma, Ling Tian, Dennis Steverson, Qinglin Yang, Yuchang Fu, W. Timothy Garvey

Diabetes. 2016 Aug; 65(8): 2380–2391. Published online 2016 May 10. doi: 10.2337/db16-0154

PMCID:: PMC4955990

Abstract Article PDF–1.8M

Select item 476805911.

Tribbles 3 Inhibits Brown Adipocyte Differentiation and Function by Suppressing Insulin Signaling

Ha-Won Jeong, Ran Hee Choi, Jamie L. McClellan, Gerardo G. Piroli, Norma Frizzell, Yu-Hua Tseng, Laurie J. Goodyear, Ho-Jin Koh

Biochem Biophys Res Commun. Author manuscript; available in PMC 2017 Feb 19.

Published in final edited form as: Biochem Biophys Res Commun. 2016 Feb 19; 470(4): 783–791. Published online 2016 Jan 20. doi: 10.1016/j.bbrc.2016.01.064

PMCID:: PMC4768059

Abstract Article PDF–1.6M

Select item 415973312.

Overexpression of TRB3 in muscle alters muscle fiber type and improves exercise capacity in mice

Ding An, Sarah J. Lessard, Taro Toyoda, Min-Young Lee, Ho-Jin Koh, Ling Qi, Michael F. Hirshman, Laurie J. Goodyear

Am J Physiol Regul Integr Comp Physiol. 2014 Jun 15; 306(12): R925–R933. Published online 2014 Apr 16. doi: 10.1152/ajpregu.00027.2014

PMCID:: PMC4159733

Abstract Article

Select item 825385913.

Tribbles homolog 3-mediated targeting the AKT/mTOR axis in mice with retinal degeneration

Irina V. Saltykova, Asif Elahi, Priyam M. Pitale, Oleg S. Gorbatyuk, Mohammad Athar, Marina S. Gorbatyuk

Cell Death Dis. 2021 Jul; 12(7): 664. Published online 2021 Jul 2. doi: 10.1038/s41419-021-03944-w

PMCID:: PMC8253859

Abstract Article PDF–4.1M

Select item 541927514.

Insulin Regulates TRB3 and Other Stress-Responsive Gene Expression through Induction of C/EBPβ

Keyong Du, Jixin Ding

Mol Endocrinol. April 1, 2009; 23(4): 475–485. doi: 10.1210/me.2008-0284

PMCID:: PMC5419275

Abstract Article

Select item 414797615.

Tribbles Homolog 3 Attenuates Mammalian Target of Rapamycin Complex-2 Signaling and Inflammation in the Diabetic Kidney

Emily Borsting, Shalin V. Patel, Anne-Emilie Declèves, Sarah J. Lee, Qazi M. Rahman, Shizuo Akira, Joe Satriano, Kumar Sharma, Volker Vallon, Robyn Cunard

J Am Soc Nephrol. 2014 Sep; 25(9): 2067–2078. Published online 2014 Mar 27. doi: 10.1681/ASN.2013070811

PMCID:: PMC4147976

Abstract Article

Select item 412480816.

Tribbles 3 Regulates the Fibrosis Cytokine TGF-β1 through ERK1/2-MAPK Signaling Pathway in Diabetic Nephropathy

Luwei Zhang, Jinhang Zhang, Xinnong Liu, Shengli Liu, Jun Tian

J Immunol Res. 2014; 2014: 240396. Published online 2014 Jul 16. doi: 10.1155/2014/240396

PMCID:: PMC4124808

Abstract Article PDF–2.2M

Select item 370712517.

Tribbles 3 Mediates Endoplasmic Reticulum Stress-Induced Insulin Resistance in Skeletal Muscle

Ho-Jin Koh, Taro Toyoda, Michelle M. Didesch, Min-Young Lee, Mark W. Sleeman, Rohit N. Kulkarni, Nicolas Musi, Michael F. Hirshman, Laurie J. Goodyear

Nat Commun. Author manuscript; available in PMC 2013 Jul 10.

Published in final edited form as: Nat Commun. 2013; 4: 1871. doi: 10.1038/ncomms2851

PMCID:: PMC3707125

Abstract Article PDF–2.2M

Select item 307844418.

Inhibition of Hepatic Glycogen Synthesis by Hyperhomocysteinemia Mediated by TRB3

Wen-Jing Liu, Lan-Qing Ma, Wei-Hua Liu, Wei Zhou, Ke-Qin Zhang, Cheng-Gang Zou

Am J Pathol. 2011 Apr; 178(4): 1489–1499. doi: 10.1016/j.ajpath.2010.12.052

PMCID:: PMC3078444

Abstract Article PDF–1.7M

Select item 291322719.

TRB3 Function in Cardiac Endoplasmic Reticulum Stress

Joan Avery, Sharon Etzion, Brian J. DeBosch, Xiaohua Jin, Traian S. Lupu, Bassel Beitinjaneh, Jacob Grand, Attila Kovacs, Nandakumar Sambandam, Anthony J. Muslin

Circ Res. Author manuscript; available in PMC 2011 May 14.

Published in final edited form as: Circ Res. 2010 May 14; 106(9): 1516–1523. Published online 2010 Apr 1. doi: 10.1161/CIRCRESAHA.109.211920