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Items: 1 to 20 of 146

1.
Reinvestigation of Disulfide-bonded Oligomeric Forms of the Unfolded Protein Response Transducer ATF6
Hibiki Koba, Shengyu Jin, Nanami Imada, Tokiro Ishikawa, Satoshi Ninagawa, Tetsuya Okada, Tetsushi Sakuma, Takashi Yamamoto, Kazutoshi Mori
Cell Struct Funct. 2020; 45(1): 9–21. Published online 2019 Dec 19. doi: 10.1247/csf.19030
PMCID:
PMC10739154
AbstractArticlePDF–1.3M
2.
Unfolded protein response factor ATF6 augments T helper cell responses and promotes mixed granulocytic airway inflammation
Dandan Wu, Xing Zhang, Kourtney M. Zimmerly, Ruoning Wang, Chunqing Wang, Russell Hunter, Xiang Wu, Matthew Campen, Meilian Liu, Xuexian O. Yang
Mucosal Immunol. Author manuscript; available in PMC 2023 Sep 27.
Published in final edited form as: Mucosal Immunol. 2023 Aug; 16(4): 499–512. Published online 2023 May 19. doi: 10.1016/j.mucimm.2023.05.007
PMCID:
PMC10530451
AbstractArticlePDF–2.4M
3.
Targeting the ATF6-mediated ER stress response and autophagy blocks integrin-driven prostate cancer progression
Amanda J. Macke, Artem N. Pachikov, Taylor E. Divita, Mary E. Morris, Chad A. LaGrange, Melissa S. Holzapfel, Anatoly V. Kubyshkin, Evgeniya Y. Zyablitskaya, Tatiana P. Makalish, Sergey N. Eremenko, Haowen Qiu, Jean-Jack M. Riethoven, George P. Hemstreet, and Armen Petrosyan
Mol Cancer Res. Author manuscript; available in PMC 2024 Mar 1.
Published in final edited form as: Mol Cancer Res. 2023 Sep 1; 21(9): 958–974. doi: 10.1158/1541-7786.MCR-23-0108
PMCID:
PMC10527559
AbstractArticlePDF–3.9M
4.
ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer
Alexandra McMellen, Tomomi M. Yamamoto, Lubna Qamar, Brooke E. Sanders, Lily L. Nguyen, Daniela Ortiz Chavez, Jaidev Bapat, Amber Berning, Miriam D. Post, Joshua Johnson, Kian Behbakht, Elmar Nurmemmedov, Edward B. Chuong, Benjamin G. Bitler
Mol Cancer Res. Author manuscript; available in PMC 2023 Jul 3.
Published in final edited form as: Mol Cancer Res. 2023 Jan 3; 21(1): 3–13. doi: 10.1158/1541-7786.MCR-22-0102
PMCID:
PMC9812934
AbstractArticlePDF–1.5M
5.
ATF6α promotes prostate cancer progression by enhancing PLA2G4A‐mediated arachidonic acid metabolism and protecting tumor cells against ferroptosis
Ru Zhao, Ye Lv, Tingting Feng, Ruojia Zhang, Luna Ge, Jihong Pan, Bo Han, Guanhua Song, Lin Wang
Prostate. 2022 Apr 1; 82(5): 617–629. Published online 2022 Jan 28. doi: 10.1002/pros.24308
PMCID:
PMC9303695
AbstractArticlePDF–2.4M
6.
ATF6-Mediated Unfolded Protein Response Facilitates Adeno-associated Virus 2 (AAV2) Transduction by Releasing the Suppression of the AAV Receptor on Endoplasmic Reticulum Stress
Mengtian Cui, Qingfang Zhao, Jing Wang, Yang Si, Shan Cheng, Wei Ding
J Virol. 2022 Feb; 96(3): e01103-21. Prepublished online 2021 Dec 1. Published online 2022 Feb 9. doi: 10.1128/JVI.01103-21
PMCID:
PMC8826799
AbstractArticlePDF–2.0M
7.
ATF6 is essential for human cone photoreceptor development
Heike Kroeger, Julia M. D. Grandjean, Wei-Chieh Jerry Chiang, Daphne D. Bindels, Rebecca Mastey, Jennifer Okalova, Amanda Nguyen, Evan T. Powers, Jeffery W. Kelly, Neil J. Grimsey, Michel Michaelides, Joseph Carroll, R. Luke Wiseman, Jonathan H. Lin
Proc Natl Acad Sci U S A. 2021 Sep 28; 118(39): e2103196118. Published online 2021 Sep 24. doi: 10.1073/pnas.2103196118
PMCID:
PMC8488632
AbstractArticlePDF–2.6M
8.
The role of activating transcription factor 6 in hydroxycamptothecin-induced fibroblast autophagy and apoptosis
Jin Tao, Hui Chen, Xiaolei Li, Jingcheng Wang
J Orthop Surg Res. 2021; 16: 1. Published online 2021 Jan 4. doi: 10.1186/s13018-020-02056-z
PMCID:
PMC7784342
AbstractArticlePDF–1.1M
9.
Pathomechanisms of ATF6-Associated Cone Photoreceptor Diseases
Wei-Chieh Jerry Chiang, Heike Kroeger, Lulu Chea, Jonathan H. Lin
Adv Exp Med Biol. Author manuscript; available in PMC 2020 Nov 5.
Published in final edited form as: Adv Exp Med Biol. 2019; 1185: 305–310. doi: 10.1007/978-3-030-27378-1_50
PMCID:
PMC7643264
AbstractArticlePDF–692K
10.
Multiexon deletion alleles of ATF6 linked to achromatopsia
Eun-Jin Lee, Wei-Chieh Jerry Chiang, Heike Kroeger, Chloe Xiaoke Bi, Daniel L. Chao, Dorota Skowronska-Krawczyk, Rebecca R. Mastey, Stephen H. Tsang, Leon Chea, Kyle Kim, Scott R. Lambert, Julia M.D. Grandjean, Britta Baumann, Isabelle Audo, Susanne Kohl, Anthony T. Moore, R. Luke Wiseman, Joseph Carroll, Jonathan H. Lin
JCI Insight. 2020 Apr 9; 5(7): e136041. Published online 2020 Apr 9. doi: 10.1172/jci.insight.136041
PMCID:
PMC7205249
AbstractArticlePDF–2.8M
11.
Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis
Erik A. Blackwood, Alina S. Bilal, Winston T. Stauffer, Adrian Arrieta, Christopher C. Glembotski
Cells. 2020 Mar; 9(3): 602. Published online 2020 Mar 3. doi: 10.3390/cells9030602
PMCID:
PMC7140506
AbstractArticlePDF–4.1M
12.
Atf6α impacts cell number by influencing survival, death and proliferation
Rohit B. Sharma, Jarin T. Snyder, Laura C. Alonso
Mol Metab. 2019 Sep; 27(Suppl): S69–S80. Published online 2019 Sep 6. doi: 10.1016/j.molmet.2019.06.005
PMCID:
PMC6768497
AbstractArticlePDF–1.1M
13.
Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein
Lars Plate, Bibiana Rius, Bianca Nguyen, Joseph C. Genereux, Jeffery W. Kelly, R. Luke Wiseman
Cell Chem Biol. Author manuscript; available in PMC 2020 Jul 18.
Published in final edited form as: Cell Chem Biol. 2019 Jul 18; 26(7): 913–925.e4. Published online 2019 May 16. doi: 10.1016/j.chembiol.2019.04.001
PMCID:
PMC6642020
AbstractArticlePDF–1.1M
14.
Characterization of Retinal Structure in ATF6-Associated Achromatopsia
Rebecca R. Mastey, Michalis Georgiou, Christopher S. Langlo, Angelos Kalitzeos, Emily J. Patterson, Thomas Kane, Navjit Singh, Ajoy Vincent, Anthony T. Moore, Stephen H. Tsang, Jonathan H. Lin, Marielle P. Young, M. Elizabeth Hartnett, Elise Héon, Susanne Kohl, Michel Michaelides, Joseph Carroll
Invest Ophthalmol Vis Sci. 2019 Jun; 60(7): 2631–2640. doi: 10.1167/iovs.19-27047
PMCID:
PMC6594318
AbstractArticlePDF–1.4M
15.
The UPR Activator ATF6 Responds to Proteotoxic and Lipotoxic Stress by Distinct Mechanisms
Arvin B. Tam, Lindsay S. Roberts, Vivek Chandra, Io Guane Rivera, Daniel K. Nomura, Douglass J. Forbes, Maho Niwa
Dev Cell. Author manuscript; available in PMC 2019 Aug 6.
Published in final edited form as: Dev Cell. 2018 Aug 6; 46(3): 327–343.e7. doi: 10.1016/j.devcel.2018.04.023
PMCID:
PMC6467773
AbstractArticlePDF–2.9M
16.
ER stress signaling has an activating transcription factor 6α (ATF6)-dependent “off-switch”
Franziska Walter, Aisling O'Brien, Caoimhín G. Concannon, Heiko Düssmann, Jochen H. M. Prehn
J Biol Chem. 2018 Nov 23; 293(47): 18270–18284. Published online 2018 Oct 4. doi: 10.1074/jbc.RA118.002121
PMCID:
PMC6254332
AbstractArticlePDF–3.5M
17.
Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins
Ryan Paxman, Lars Plate, Erik A Blackwood, Chris Glembotski, Evan T Powers, R Luke Wiseman, Jeffery W Kelly
eLife. 2018; 7: e37168. Published online 2018 Aug 7. doi: 10.7554/eLife.37168
PMCID:
PMC6080950
AbstractArticlePDF–3.6M
18.
The unfolded protein response regulator ATF6 promotes mesodermal differentiation
Heike Kroeger, Neil Grimsey, Ryan Paxman, Wei-Chieh Chiang, Lars Plate, Ying Jones, Peter X. Shaw, JoAnn Trejo, Stephen H. Tsang, Evan Powers, Jeffery W. Kelly, R. Luke Wiseman, Jonathan H. Lin
Sci Signal. Author manuscript; available in PMC 2018 May 17.
Published in final edited form as: Sci Signal. 2018 Feb 13; 11(517): eaan5785. Published online 2018 Feb 13. doi: 10.1126/scisignal.aan5785
PMCID:
PMC5957084
AbstractArticlePDF–1.5M
19.
High expression of active ATF6 aggravates endoplasmic reticulum stress-induced vascular endothelial cell apoptosis through the mitochondrial apoptotic pathway
Jingyong Huang, Li Wan, Heping Lu, Xiaoqiang Li
Mol Med Rep. 2018 May; 17(5): 6483–6489. Published online 2018 Mar 1. doi: 10.3892/mmr.2018.8658
PMCID:
PMC5928631
AbstractArticlePDF–1.2M
20.
Expression of ATF6 as a marker of pre-cancerous atypical change in ulcerative colitis-associated colorectal cancer: a potential role in the management of dysplasia
Marie Hanaoka, Toshiaki Ishikawa, Megumi Ishiguro, Michiyo Tokura, Shinichi Yamauchi, Akifumi Kikuchi, Hiroyuki Uetake, Masamichi Yasuno, Tatsuyuki Kawano
J Gastroenterol. 2018; 53(5): 631–641. Published online 2017 Sep 7. doi: 10.1007/s00535-017-1387-1
PMCID:
PMC5910497
AbstractArticlePDF–1.5M

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