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Select item 90207951.

Orexin 1 Receptor Antagonism in the Basolateral Amygdala Shifts the Balance from Pro- to Anti-stress Signaling and Behavior

Jazmine D.W. Yaeger, Kevin T. Krupp, Benjamin M. Jacobs, Benard O. Onserio, Brandon L. Meyerink, Jacob T. Cain, Patrick J. Ronan, Kenneth J. Renner, Ralph J. DiLeone, Cliff H. Summers

Biol Psychiatry. Author manuscript; available in PMC 2023 May 1.

Published in final edited form as: Biol Psychiatry. 2022 May 1; 91(9): 841–852. Published online 2022 Jan 19. doi: 10.1016/j.biopsych.2021.12.019

PMCID:: PMC9020795

Abstract Article PDF–2.3M

Select item 85874852.

Nucleus Accumbens Shell Orexin-1 Receptors Are Not Needed For Single-Bottle Limited Daily Access Alcohol Intake in C57BL/6 mice

Kelly Lei, Claudina Kwok, Frederic W. Hopf

Alcohol. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Alcohol. 2020 Dec; 89: 139–146. Published online 2020 Sep 25. doi: 10.1016/j.alcohol.2020.09.003

PMCID:: PMC8587485

Abstract Article PDF–808K

Select item 77942933.

Differential importance of nucleus accumbens Ox1Rs and AMPARs for female and male mouse binge alcohol drinking

Claudina Kwok, Kelly Lei, Vincent Pedrozo, Lexy Anderson, Shahbaj Ghotra, Margaret Walsh, Laura Li, JiHwan Yu, Frederic Woodward Hopf

Sci Rep. 2021; 11: 231. Published online 2021 Jan 8. doi: 10.1038/s41598-020-79935-2

PMCID:: PMC7794293

Abstract Article PDF–3.7M

Select item 61955374.

Bidirectional and context-dependent changes in theta and gamma oscillatory brain activity in noradrenergic cell-specific Hypocretin/Orexin receptor 1-KO mice

Sha Li, Paul Franken, Anne Vassalli

Sci Rep. 2018; 8: 15474. Published online 2018 Oct 19. doi: 10.1038/s41598-018-33069-8

PMCID:: PMC6195537

Abstract Article PDF–6.1M

Select item 50659385.

Orexin-1 receptor blockade suppresses compulsive-like alcohol drinking in mice

Kelly Lei, Scott A. Wegner, Ji-Hwan Yu, F. Woodward Hopf

Neuropharmacology. Author manuscript; available in PMC 2017 Nov 1.

Published in final edited form as: Neuropharmacology. 2016 Nov; 110(Pt A): 431–437. Published online 2016 Aug 11. doi: 10.1016/j.neuropharm.2016.08.008

PMCID:: PMC5065938

Abstract Article PDF–1.8M

Select item 46745556.

Comprehensive Behavioral Analysis of Male Ox1r^−/− Mice Showed Implication of Orexin Receptor-1 in Mood, Anxiety, and Social Behavior

Md. G. Abbas, Hirotaka Shoji, Shingo Soya, Mari Hondo, Tsuyoshi Miyakawa, Takeshi Sakurai

Front Behav Neurosci. 2015; 9: 324. Published online 2015 Dec 10. doi: 10.3389/fnbeh.2015.00324

PMCID:: PMC4674555

Abstract Article PDF–3.3M

Select item 34028807.

Hypocretin-1 receptors regulate the reinforcing and reward-enhancing effects of cocaine: pharmacological and behavioral genetics evidence

Jonathan A. Hollander, Don Pham, Christie D. Fowler, Paul J. Kenny

Front Behav Neurosci. 2012; 6: 47. Published online 2012 Jul 24. doi: 10.3389/fnbeh.2012.00047

PMCID:: PMC3402880

Abstract Article PDF–1005K

Select item 108837528.

Whole Brain Mapping of Orexin Receptor mRNA Expression Visualized by Branched In Situ Hybridization Chain Reaction

Yousuke Tsuneoka, Hiromasa Funato

eNeuro. 2024 Feb; 11(2): ENEURO.0474-23.2024. Prepublished online 2024 Jan 10. Published online 2024 Feb 6. doi: 10.1523/ENEURO.0474-23.2024

PMCID:: PMC10883752

Abstract Article PDF–45M

Select item 96566649.

Antagonization of OX₁ Receptor Potentiates CB₂ Receptor Function in Microglia from APP_Sw/Ind Mice Model

Iu Raïch, Joan Biel Rebassa, Jaume Lillo, Arnau Cordomi, Rafael Rivas-Santisteban, Alejandro Lillo, Irene Reyes-Resina, Rafael Franco, Gemma Navarro

Int J Mol Sci. 2022 Nov; 23(21): 12801. Published online 2022 Oct 24. doi: 10.3390/ijms232112801

PMCID:: PMC9656664

Abstract Article PDF–3.4M

Select item 957606210.

The hypothalamic RFamide, QRFP, increases feeding and locomotor activity: The role of Gpr103 and orexin receptors

Chris Cook, Nicolas Nunn, Amy A. Worth, David A. Bechtold, Todd Suter, Susan Gackeheimer, Lisa Foltz, Paul J. Emmerson, Michael A. Statnick, Simon M. Luckman

PLoS One. 2022; 17(10): e0275604. Published online 2022 Oct 17. doi: 10.1371/journal.pone.0275604

PMCID:: PMC9576062

Abstract Article PDF–2.9M

Select item 841338211.

Orexin receptors 1 and 2 in serotonergic neurons differentially regulate peripheral glucose metabolism in obesity

Xing Xiao, Gagik Yeghiazaryan, Simon Hess, Paul Klemm, Anna Sieben, André Kleinridders, Donald A. Morgan, F. Thomas Wunderlich, Kamal Rahmouni, Dong Kong, Thomas E. Scammell, Bradford B. Lowell, Peter Kloppenburg, Jens C. Brüning, A. Christine Hausen

Nat Commun. 2021; 12: 5249. Published online 2021 Sep 2. doi: 10.1038/s41467-021-25380-2

PMCID:: PMC8413382

Abstract Article PDF–8.1M

Select item 666611212.

Altered Sleep Homeostasis after Restraint Stress in 5-HTT Knock-Out Male Mice: A Role for Hypocretins

Adeline Rachalski, Chloé Alexandre, Jean-François Bernard, Françoise Saurini, Klaus-Peter Lesch, Michel Hamon, Joëlle Adrien, Véronique Fabre

J Neurosci. 2009 Dec 9; 29(49): 15575–15585. doi: 10.1523/JNEUROSCI.3138-09.2009

PMCID:: PMC6666112

Abstract Article PDF–1.6M

Select item 524596513.

Peripherally administered orexin improves survival of mice with endotoxin shock

Yasuhiro Ogawa, Yoko Irukayama-Tomobe, Nobuyuki Murakoshi, Maiko Kiyama, Yui Ishikawa, Naoto Hosokawa, Hiromu Tominaga, Shuntaro Uchida, Saki Kimura, Mika Kanuka, Miho Morita, Michito Hamada, Satoru Takahashi, Yu Hayashi, Masashi Yanagisawa

eLife. 2016; 5: e21055. Published online 2016 Dec 30. doi: 10.7554/eLife.21055

PMCID:: PMC5245965

Abstract Article PDF–2.6M

Select item 503925614.

Hypocretin/Orexin Peptides Alter Spike Encoding by Serotonergic Dorsal Raphe Neurons through Two Distinct Mechanisms That Increase the Late Afterhyperpolarization

Masaru Ishibashi, Iryna Gumenchuk, Kenichi Miyazaki, Takafumi Inoue, William N. Ross, Christopher S. Leonard

J Neurosci. 2016 Sep 28; 36(39): 10097–10115. doi: 10.1523/JNEUROSCI.0635-16.2016

PMCID:: PMC5039256

Abstract Article PDF–4.4M

Select item 436194115.

Anxiolytic function of the orexin 2/hypocretin A receptor in the basolateral amygdala

David H. Arendt, James Hassell, Hao Li, Justin K. Achua, Douglas J. Guarnieri, Ralph J. DiLeone, Patrick J. Ronan, Cliff H. Summers

Psychoneuroendocrinology. Author manuscript; available in PMC 2015 Mar 17.

Published in final edited form as: Psychoneuroendocrinology. 2014 Feb; 40: 17–26. Published online 2013 Oct 30. doi: 10.1016/j.psyneuen.2013.10.010

PMCID:: PMC4361941

Abstract Article PDF–976K

Select item 347429616.

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors

Michael M. Scott, Jacob N. Marcus, Ami Pettersen, Shari G. Birnbaum, Takatoshi Mochizuki, Thomas E. Scammell, Eric J. Nestler, Joel K. Elmquist, Michael Lutter

Behav Brain Res. Author manuscript; available in PMC 2012 Oct 17.

Published in final edited form as: Behav Brain Res. 2011 Sep 23; 222(2): 289–294. Published online 2011 Mar 4. doi: 10.1016/j.bbr.2011.02.044

PMCID:: PMC3474296

Abstract Article PDF–723K

Select item 307643717.

Cholinergic Modulation of Narcoleptic Attacks in Double Orexin Receptor Knockout Mice

Mike Kalogiannis, Emily Hsu, Jon T. Willie, Richard M. Chemelli, Yaz Y. Kisanuki, Masashi Yanagisawa, Christopher S. Leonard

PLoS One. 2011; 6(4): e18697. Published online 2011 Apr 13. doi: 10.1371/journal.pone.0018697

PMCID:: PMC3076437

Abstract Article PDF–827K

Select item 294581818.

Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in laterodorsal tegmental neurons

M. Kalogiannis, S.L. Grupke, P.E. Potter, J.G. Edwards, R.M. Chemelli, Y.Y. Kisanuki, M. Yanagisawa, C.S. Leonard

Eur J Neurosci. Author manuscript; available in PMC 2011 Jul 1.

Published in final edited form as: Eur J Neurosci. 2010 Jul; 32(1): 130–142. Published online 2010 Jun 22. doi: 10.1111/j.1460-9568.2010.07259.x

PMCID:: PMC2945818

Abstract Article PDF–1.6M

Select item 285424519.

Ghrelin increases the rewarding value of high fat diet in an orexin-dependent manner

Mario Perello, Ichiro Sakata, Shari Birnbaum, Jen-Chieh Chuang, Sherri Osborne-Lawrence, Sherry A. Rovinsky, Jakub Woloszyn, Masashi Yanagisawa, Michael Lutter, Jeffrey M. Zigman

Biol Psychiatry. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Biol Psychiatry. 2010 May 1; 67(9): 880–886. Published online 2009 Dec 24. doi: 10.1016/j.biopsych.2009.10.030