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Select item 109920961.

Polymorphism of formyl peptide receptor 1 (FPR1) reduces the therapeutic efficiency and antitumor immunity after neoadjuvant chemoradiotherapy (CCRT) treatment in locally advanced rectal cancer

Shu-Fen Chiang, Kevin Chih-Yang Huang, William Tzu-Liang Chen, Tsung-Wei Chen, Tao-Wei Ke, K. S. Clifford Chao

Cancer Immunol Immunother. 2021 Oct; 70(10): 2937–2950. Published online 2021 Mar 13. doi: 10.1007/s00262-021-02894-8

PMCID:: PMC10992096

Abstract Article PDF–3.3M

Select item 100380222.

Rs867228 in FPR1 accelerates the manifestation of luminal B breast cancer

Vincent Carbonnier, Julie Le Naour, Thomas Bachelot, Erika Vacchelli, Fabrice André, Suzette Delaloge, Guido Kroemer

Oncoimmunology. 2023; 12(1): 2189823. Published online 2023 Mar 21. doi: 10.1080/2162402X.2023.2189823

PMCID:: PMC10038022

Abstract Article PDF–1.4M

Select item 96944883.

Amyloid beta and its naturally occurring N-terminal variants are potent activators of human and mouse formyl peptide receptor 1

Lukas Busch, Zukaa al Taleb, Yu-Liang Tsai, Vu Thu Thuy Nguyen, Qi Lu, Christopher V. Synatschke, Kristina Endres, Bernd Bufe

J Biol Chem. 2022 Dec; 298(12): 102642. Published online 2022 Oct 27. doi: 10.1016/j.jbc.2022.102642

PMCID:: PMC9694488

Abstract Article PDF–3.7M

Select item 93514944.

Agonist concentration–dependent changes in FPR1 conformation lead to biased signaling for selective activation of phagocyte functions

Junlin Wang, Richard D. Ye

Proc Natl Acad Sci U S A. 2022 Aug 2; 119(31): e2201249119. Published online 2022 Jul 25. doi: 10.1073/pnas.2201249119

PMCID:: PMC9351494

Abstract Article PDF–2.2M

Select item 81281755.

An independent predictor of poor prognosis in locally advanced rectal cancer: rs867228 in formyl peptide receptor 1 (FPR1)

Shu-Fen Chiang, Kevin Chih-Yang Huang, William Tzu-Liang Chen, Tsung-Wei Chen, Tao-Wei Ke, K. S. Clifford Chao

Oncoimmunology. 2021; 10(1): 1926074. Published online 2021 May 14. doi: 10.1080/2162402X.2021.1926074

PMCID:: PMC8128175

Abstract Article PDF–602K

Select item 78011196.

A major genetic accelerator of cancer diagnosis: rs867228 in FPR1

Zsofia Sztupinszki, Julie Le Naour, Erika Vacchelli, Pierre Laurent-Puig, Suzette Delaloge, Zoltan Szallasi, Guido Kroemer

Oncoimmunology. 2021; 10(1): 1859064. Published online 2021 Jan 6. doi: 10.1080/2162402X.2020.1859064

PMCID:: PMC7801119

Article PDF–496K

Select item 77340427.

No impact of cancer and plague-relevant FPR1 polymorphisms on COVID-19

Adriana Petrazzuolo, Julie Le Naour, Erika Vacchelli, Pascale Gaussem, Syrine Ellouze, Georges Jourdi, Eric Solary, Michaela Fontenay, David M. Smadja, Guido Kroemer

Oncoimmunology. 2020; 9(1): 1857112. Published online 2020 Dec 8. doi: 10.1080/2162402X.2020.1857112

PMCID:: PMC7734042

Abstract Article PDF–377K

Select item 72266028.

Exploring Biased Agonism at FPR1 as a Means to Encode Danger Sensing

Jieny Gröper, Gabriele M. König, Evi Kostenis, Volker Gerke, Carsten A. Raabe, Ursula Rescher

Cells. 2020 Apr; 9(4): 1054. Published online 2020 Apr 23. doi: 10.3390/cells9041054

PMCID:: PMC7226602

Abstract Article PDF–4.2M

Select item 71998099.

The ambiguous role of FPR1 in immunity and inflammation

Erika Vacchelli, Julie Le Naour, Guido Kroemer

Oncoimmunology. 2020; 9(1): 1760061. Published online 2020 Apr 30. doi: 10.1080/2162402X.2020.1760061

PMCID:: PMC7199809

Article PDF–759K

Select item 710115210.

FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis

Jack Leslie, Ben J.M. Millar, Alicia del Carpio Pons, Rachel A. Burgoyne, Joseph D. Frost, Ben S. Barksby, Saimir Luli, Jon Scott, A. John Simpson, Jack Gauldie, Lynne A. Murray, Donna K. Finch, Alan M. Carruthers, John Ferguson, Matthew A. Sleeman, David Rider, Rachel Howarth, Christopher Fox, Fiona Oakley, Andrew J. Fisher, Derek A. Mann, Lee A. Borthwick

JCI Insight. 2020 Feb 27; 5(4): e125937. Published online 2020 Feb 27. doi: 10.1172/jci.insight.125937

PMCID:: PMC7101152

Abstract Article PDF–22M

Select item 683917411.

Targeting the Formyl Peptide Receptor type 1 to prevent the adhesion of ovarian cancer cells onto mesothelium and subsequent invasion

Michele Minopoli, Giovanni Botti, Vincenzo Gigantino, Concetta Ragone, Sabrina Sarno, Maria Letizia Motti, Giosuè Scognamiglio, Stefano Greggi, Cono Scaffa, Maria Serena Roca, Maria Patrizia Stoppelli, Gennaro Ciliberto, Nunzia Simona Losito, Maria Vincenza Carriero

J Exp Clin Cancer Res. 2019; 38: 459. Published online 2019 Nov 8. doi: 10.1186/s13046-019-1465-8

PMCID:: PMC6839174

Abstract Article PDF–2.9M

Select item 591227612.

Expression and Functions of Formyl Peptide Receptor 1 in Drug-Resistant Bladder Cancer

Xue Jiang, Ting Lei, Man Zhang

Technol Cancer Res Treat. 2018; 17: 1533034618769413. Published online 2018 Apr 17. doi: 10.1177/1533034618769413

PMCID:: PMC5912276

Abstract Article PDF–643K

Select item 590139513.

Whole blood FPR1 mRNA expression predicts both non‐small cell and small cell lung cancer

Scott Morris, Anil Vachani, Harvey I. Pass, William N. Rom, Kirk Ryden, Glen J. Weiss, D. K. Hogarth, George Runger, Donald Richards, Troy Shelton, David W. Mallery

Int J Cancer. 2018 Jun 1; 142(11): 2355–2362. Published online 2018 Jan 30. doi: 10.1002/ijc.31245

PMCID:: PMC5901395

Abstract Article PDF–343K

Select item 572161214.

Targeting the cross-talk between Urokinase receptor and Formyl peptide receptor type 1 to prevent invasion and trans-endothelial migration of melanoma cells

Concetta Ragone, Michele Minopoli, Vincenzo Ingangi, Giovanni Botti, Federica Fratangelo, Antonello Pessi, Maria Patrizia Stoppelli, Paolo Antonio Ascierto, Gennaro Ciliberto, Maria Letizia Motti, Maria Vincenza Carriero

J Exp Clin Cancer Res. 2017; 36: 180. Published online 2017 Dec 8. doi: 10.1186/s13046-017-0650-x

PMCID:: PMC5721612

Abstract Article PDF–6.2M

Select item 495024215.

The role of formyl peptide receptor 1 (FPR1) in neuroblastoma tumorigenesis

Igor Snapkov, Carl Otto Öqvist, Yngve Figenschau, Per Kogner, John Inge Johnsen, Baldur Sveinbjørnsson

BMC Cancer. 2016; 16: 490. Published online 2016 Jul 18. doi: 10.1186/s12885-016-2545-1

PMCID:: PMC4950242

Abstract Article PDF–2.0M

Select item 377970516.

Identification of C-terminal Phosphorylation Sites of N-Formyl Peptide Receptor-1 (FPR1) in Human Blood Neutrophils

Walid S. Maaty, Connie I. Lord, Jeannie M. Gripentrog, Marcia Riesselman, Gal Keren-Aviram, Ting Liu, Edward A. Dratz, Brian Bothner, Algirdas J. Jesaitis

J Biol Chem. 2013 Sep 20; 288(38): 27042–27058. Published online 2013 Jul 19. doi: 10.1074/jbc.M113.484113