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Items: 1 to 20 of 24

1.
Ubiquitin chains earmark GPCRs for BBSome-mediated removal from cilia
Swapnil Rohidas Shinde, Andrew R. Nager, Maxence V. Nachury
J Cell Biol. 2020 Dec 7; 219(12): e202003020. Published online 2020 Nov 13. doi: 10.1083/jcb.202003020
PMCID:
PMC7716378
ArticlePDF–4.5M
2.
Congenital Cataract in Gpr161vl/vl Mice Is Modified by Proximal Chromosome 15
Bo I. Li, Myka R. Ababon, Paul G. Matteson, Yong Lin, Vikas Nanda, James H. Millonig
PLoS One. 2017; 12(1): e0170724. Published online 2017 Jan 30. doi: 10.1371/journal.pone.0170724
PMCID:
PMC5279759
ArticlePDF–2.3M
3.
Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling
Francesc R. Garcia-Gonzalo, Siew C. Phua, Elle C. Roberson, Galo Garcia, III, Monika Abedin, Stéphane Schurmans, Takanari Inoue, Jeremy F. Reiter
Dev Cell. Author manuscript; available in PMC 2016 Aug 24.
Published in final edited form as: Dev Cell. 2015 Aug 24; 34(4): 400–409. doi: 10.1016/j.devcel.2015.08.001
PMCID:
PMC4557815
ArticlePDF–1.2M
4.
Dominant negative GPR161 rare variants are risk factors of human spina bifida
Sung-Eun Kim, Yunping Lei, Sun-Hee Hwang, Bogdan J Wlodarczyk, Saikat Mukhopadhyay, Gary M Shaw, M Elizabeth Ross, Richard H Finnell
Hum Mol Genet. 2019 Jan 15; 28(2): 200–208. Published online 2018 Sep 25. doi: 10.1093/hmg/ddy339
PMCID:
PMC6321953
ArticlePDF–20M
5.
Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium
Kasturi Pal, Sun-hee Hwang, Bandarigoda Somatilaka, Hemant Badgandi, Peter K. Jackson, Kathryn DeFea, Saikat Mukhopadhyay
J Cell Biol. 2016 Mar 28; 212(7): 861–875. doi: 10.1083/jcb.201506132
PMCID:
PMC4810300
ArticlePDF–2.4M
6.
The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development
Paul G. Matteson, Jigar Desai, Ron Korstanje, Gloria Lazar, Tanya E. Borsuk, Jarod Rollins, Sindhuja Kadambi, Jamie Joseph, Taslima Rahman, Jason Wink, Rym Benayed, Beverly Paigen, James H. Millonig
Proc Natl Acad Sci U S A. 2008 Feb 12; 105(6): 2088–2093. Published online 2008 Feb 4. doi: 10.1073/pnas.0705657105
PMCID:
PMC2538885
ArticlePDF–925K
7.
Pax3 lineage-specific deletion of Gpr161 is associated with spinal neural tube and craniofacial malformations during embryonic development
Sung-Eun Kim, Pooja J. Chothani, Rehana Shaik, Westley Pollard, Richard H. Finnell
Dis Model Mech. 2023 Nov 1; 16(11): dmm050277. Published online 2023 Nov 28. doi: 10.1242/dmm.050277
PMCID:
PMC10694864
Article
8.
Tulp3 regulates renal cystogenesis by trafficking of cystoproteins to cilia
Sun-Hee Hwang, Bandarigoda N. Somatilaka, Hemant Badgandi, Vivek Reddy Palicharla, Rebecca Walker, John M. Shelton, Feng Qian, Saikat Mukhopadhyay
Curr Biol. Author manuscript; available in PMC 2020 Mar 4.
Published in final edited form as: Curr Biol. 2019 Mar 4; 29(5): 790–802.e5. Published online 2019 Feb 21. doi: 10.1016/j.cub.2019.01.047
PMCID:
PMC6401225
ArticlePDF–4.0M
9.
The orphan G protein coupled receptor 161 is required for left-right patterning
TinChung Leung, Jasper E. Humbert, Anna M. Stauffer, Kathryn E. Giger, Hui Chen, Huai-Jen Tsai, Chuan Wang, Tooraj Mirshahi, Janet D. Robishaw
Dev Biol. Author manuscript; available in PMC 2015 Nov 10.
Published in final edited form as: Dev Biol. 2008 Nov 1; 323(1): 31–40. Published online 2008 Aug 7. doi: 10.1016/j.ydbio.2008.08.001
PMCID:
PMC4639926
ArticlePDF–988K
10.
Wnt1 Lineage Specific Deletion of Gpr161 Results in Embryonic Midbrain Malformation and Failure of Craniofacial Skeletal Development
Sung-Eun Kim, Karla Robles-Lopez, Xuanye Cao, Kristyn Liu, Pooja J. Chothani, Nikitha Bhavani, Lauren Rahman, Saikat Mukhopadhyay, Bogdan J. Wlodarczyk, Richard H. Finnell
Front Genet. 2021; 12: 761418. Published online 2021 Nov 23. doi: 10.3389/fgene.2021.761418
PMCID:
PMC8650154
ArticlePDF–2.4M
11.
Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner
Sun-Hee Hwang, Bandarigoda N Somatilaka, Kevin White, Saikat Mukhopadhyay
eLife. 2021; 10: e67121. Published online 2021 Aug 4. doi: 10.7554/eLife.67121
PMCID:
PMC8378848
ArticlePDF–9.0M
12.
The ciliary phosphatidylinositol phosphatase Inpp5e plays positive and negative regulatory roles in Shh signaling
Sandii Constable, Alyssa B. Long, Katharine A. Floyd, Stéphane Schurmans, Tamara Caspary
Development. 2020 Feb 1; 147(3): dev183301. Published online 2020 Feb 3. doi: 10.1242/dev.183301
PMCID:
PMC7033722
Article
13.
The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner
Sun-hee Hwang, Kevin A. White, Bandarigoda N. Somatilaka, John M. Shelton, James A. Richardson, Saikat Mukhopadhyay
Development. 2018 Jan 1; 145(1): dev154054. doi: 10.1242/dev.154054
PMCID:
PMC5825871
Article
14.
Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis
Issei S. Shimada, Sun-Hee Hwang, Bandarigoda N. Somatilaka, Xin Wang, Patryk Skowron, Jiwoong Kim, Min Kim, John M. Shelton, Veena Rajaram, Zhenyu Xuan, Michael D. Taylor, Saikat Mukhopadhyay
Cell Rep. Author manuscript; available in PMC 2018 Feb 15.
Published in final edited form as: Cell Rep. 2018 Jan 30; 22(5): 1169–1184. doi: 10.1016/j.celrep.2018.01.018
PMCID:
PMC5813698
ArticlePDF–2.5M
15.
Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities
Issei S. Shimada, Bandarigoda N. Somatilaka, Sun-Hee Hwang, Ashley G. Anderson, John M. Shelton, Veena Rajaram, Genevieve Konopka, Saikat Mukhopadhyay
Dev Biol. Author manuscript; available in PMC 2020 Jun 1.
Published in final edited form as: Dev Biol. 2019 Jun 1; 450(1): 47–62. Published online 2019 Mar 23. doi: 10.1016/j.ydbio.2019.03.011
PMCID:
PMC6497453
ArticlePDF–5.3M
16.
Tubby family proteins are adapters for ciliary trafficking of integral membrane proteins
Hemant B. Badgandi, Sun-hee Hwang, Issei S. Shimada, Evan Loriot, Saikat Mukhopadhyay
J Cell Biol. 2017 Mar 6; 216(3): 743–760. doi: 10.1083/jcb.201607095
PMCID:
PMC5350516
ArticlePDF–3.1M
17.
The G protein-coupled receptor repertoires of human and mouse
Demetrios K. Vassilatis, John G. Hohmann, Hongkui Zeng, Fusheng Li, Jane E. Ranchalis, Marty T. Mortrud, Analisa Brown, Stephanie S. Rodriguez, John R. Weller, Abbie C. Wright, John E. Bergmann, George A. Gaitanaris
Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8): 4903–4908. Published online 2003 Apr 4. doi: 10.1073/pnas.0230374100
PMCID:
PMC153653
ArticlePDF–955K
18.
Transcriptome Analysis of Mouse Stem Cells and Early Embryos
Alexei A Sharov, Yulan Piao, Ryo Matoba, Dawood B Dudekula, Yong Qian, Vincent VanBuren, Geppino Falco, Patrick R Martin, Carole A Stagg, Uwem C Bassey, Yuxia Wang, Mark G Carter, Toshio Hamatani, Kazuhiro Aiba, Hidenori Akutsu, Lioudmila Sharova, Tetsuya S Tanaka, Wendy L Kimber, Toshiyuki Yoshikawa, Saied A Jaradat, Serafino Pantano, Ramaiah Nagaraja, Kenneth R Boheler, Dennis Taub, Richard J Hodes, Dan L Longo, David Schlessinger, Jonathan Keller, Emily Klotz, Garnett Kelsoe, Akihiro Umezawa, Angelo L Vescovi, Janet Rossant, Tilo Kunath, Brigid L. M Hogan, Anna Curci, Michele D'Urso, Janet Kelso, Winston Hide, Minoru S. H Ko
PLoS Biol. 2003 Dec; 1(3): e74. Published online 2003 Dec 22. doi: 10.1371/journal.pbio.0000074
PMCID:
PMC300684
ArticlePDF–572K
19.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
ArticlePDF–3.0M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
ArticlePDF–3.8M

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