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Select item 69889181.

Metabolic syndrome diminishes insulin-induced Akt activation and causes a redistribution of Akt-interacting proteins in cardiomyocytes

Huguet V. Landa-Galvan, Emmanuel Rios-Castro, Tatiana Romero-Garcia, Angelica Rueda, Jesus Alberto Olivares-Reyes

PLoS One. 2020; 15(1): e0228115. Published online 2020 Jan 29. doi: 10.1371/journal.pone.0228115

PMCID:: PMC6988918

Abstract Article PDF–1.7M

Select item 67297162.

Opposing Extracellular Signal-Regulated Kinase and Akt Pathways Control Schwann Cell Myelination

Toru Ogata, Satoru Iijima, Shinya Hoshikawa, Toshiki Miura, Shin-ichi Yamamoto, Hiromi Oda, Kozo Nakamura, Sakae Tanaka

J Neurosci. 2004 Jul 28; 24(30): 6724–6732. doi: 10.1523/JNEUROSCI.5520-03.2004

PMCID:: PMC6729716

Abstract Article PDF–475K

Select item 67257403.

Akt Contributes to Neuroprotection by Hypothermia against Cerebral Ischemia in Rats

Heng Zhao, Takayoshi Shimohata, Jade Q. Wang, Guohua Sun, David W. Schaal, Robert M. Sapolsky, Gary K. Steinberg

J Neurosci. 2005 Oct 19; 25(42): 9794–9806. doi: 10.1523/JNEUROSCI.3163-05.2005

PMCID:: PMC6725740

Abstract Article PDF–1.3M

Select item 65289344.

Deferoxamine promotes mesenchymal stem cell homing in noise‐induced injured cochlea through PI3K/AKT pathway

A.A. Peyvandi, H.‐A. Abbaszadeh, N. Ahmady Roozbahany, A. Pourbakht, S. Khoshsirat, H. Haddadzade Niri, H. Peyvandi, S. Niknazar

Cell Prolif. 2018 Apr; 51(2): e12434. Published online 2018 Jan 17. doi: 10.1111/cpr.12434

PMCID:: PMC6528934

Abstract Article PDF–1.0M

Select item 59558315.

Urinary bladder organ hypertrophy is partially regulated by Akt1-mediated protein synthesis pathway

Li-Ya Qiao, Chunmei Xia, Shanwei Shen, Seong Ho Lee, Paul H Ratz, Matthew O Fraser, Amy Miner, John E Speich, Jeffrey J Lysiak, William D Steers

Life Sci. Author manuscript; available in PMC 2019 May 15.

Published in final edited form as: Life Sci. 2018 May 15; 201: 63–71. Published online 2018 Mar 21. doi: 10.1016/j.lfs.2018.03.041

PMCID:: PMC5955831

Abstract Article PDF–772K

Select item 46764076.

Akt kinase C-terminal modifications control activation loop dephosphorylation and enhance insulin response

Tung O. Chan, Jin Zhang, Brian C. Tiegs, Brian Blumhof, Linda Yan, Nikhil Keny, Morgan Penny, Xue Li, John M. Pascal, Roger S. Armen, Ulrich Rodeck, Raymond B. Penn

Biochem J. Author manuscript; available in PMC 2015 Dec 11.

Published in final edited form as: Biochem J. 2015 Oct 1; 471(1): 37–51. Published online 2015 Jul 22. doi: 10.1042/BJ20150325

PMCID:: PMC4676407

Abstract Article PDF–1.6M

Select item 43984307.

Atorvastatin Calcium Inhibits Phenotypic Modulation of PDGF-BB-Induced VSMCs via Down-Regulation the Akt Signaling Pathway

Shuang Chen, Baoqin Liu, Dehui Kong, Si Li, Chao Li, Huaqin Wang, Yingxian Sun

PLoS One. 2015; 10(4): e0122577. Published online 2015 Apr 15. doi: 10.1371/journal.pone.0122577

PMCID:: PMC4398430

Abstract Article PDF–7.2M

Select item 39908468.

Protein Kinase B (PKB/AKT1) Formed Signaling Complexes with Mitochondrial Proteins and Prevented Glycolytic Energy Dysfunction in Cultured Cardiomyocytes During Ischemia-Reperfusion Injury

Wu Deng, Hsin-Bang Leu, Yumay Chen, Yu-Han Chen, Christine M. Epperson, Charity Juang, Ping H. Wang

Endocrinology. 2014 May; 155(5): 1618–1628. Published online 2014 Mar 6. doi: 10.1210/en.2013-1817

PMCID:: PMC3990846

Abstract Article

Select item 38582839.

PI3K/Akt Signal Pathway Involved in the Cognitive Impairment Caused by Chronic Cerebral Hypoperfusion in Rats

Yi Shu, Hong Zhang, Tao Kang, Jun-jian Zhang, Ying Yang, Hui Liu, Lei Zhang

PLoS One. 2013; 8(12): e81901. Published online 2013 Dec 10. doi: 10.1371/journal.pone.0081901

PMCID:: PMC3858283

Abstract Article PDF–761K

Select item 374695410.

Cardioprotection in the aging, diabetic heart: the loss of protective Akt signalling

Hannah J. Whittington, Idris Harding, Clemency I.M. Stephenson, Robert Bell, Derek J. Hausenloy, Mihaela M. Mocanu, Derek M. Yellon

Cardiovasc Res. 2013 Sep 1; 99(4): 694–704. Published online 2013 May 30. doi: 10.1093/cvr/cvt140

PMCID:: PMC3746954

Abstract Article PDF–830K

Select item 367768611.

Akt Activation Protects Liver Cells from Apoptosis in Rats during Acute Cold Exposure

Jiye Wang, Yaoming Chen, Wenbin Zhang, Gang Zheng, Shanshan Meng, Honglei Che, Tao Ke, Jingrun Yang, Jingyuan Chen, Wenjing Luo

Int J Biol Sci. 2013; 9(5): 509–517. Published online 2013 May 25. doi: 10.7150/ijbs.5220

PMCID:: PMC3677686

Abstract Article PDF–944K

Select item 365773612.

EFFECTS OF ESTROGEN AND AGING ON THE SYNAPTIC DISTRIBUTION OF PHOSPHORYLATED AKT-IMMUNOREACTIVITY IN THE CA1 REGION OF THE FEMALE RAT HIPPOCAMPUS

Murat Yildirim, William G.M. Janssen, W.Y. Wendy Lou, Keith T. Akama, Bruce S. McEwen, Teresa A. Milner, John H. Morrison

Brain Res. Author manuscript; available in PMC 2013 May 20.

Published in final edited form as: Brain Res. 2011 Mar 16; 1379: 98–108. Published online 2010 Aug 13. doi: 10.1016/j.brainres.2010.07.053

PMCID:: PMC3657736

Abstract Article PDF–1.0M

Select item 354674113.

High Density Lipoprotein Protects Mesenchymal Stem Cells from Oxidative Stress-Induced Apoptosis via Activation of the PI3K/Akt Pathway and Suppression of Reactive Oxygen Species

Jianfeng Xu, Juying Qian, Xinxing Xie, Li Lin, Yunzeng Zou, Mingqiang Fu, Zheyong Huang, Guoping Zhang, Yangang Su, Junbo Ge

Int J Mol Sci. 2012; 13(12): 17104–17120. Published online 2012 Dec 13. doi: 10.3390/ijms131217104

PMCID:: PMC3546741

Abstract Article PDF–1.8M

Select item 348811514.

Akt/PKB Controls the Activity-Dependent Bulk Endocytosis of Synaptic Vesicles

Karen J Smillie, Michael A Cousin

Traffic. 2012 Jul; 13(7): 1004–1011. Published online 2012 Apr 29. doi: 10.1111/j.1600-0854.2012.01365.x

PMCID:: PMC3488115

Abstract Article PDF–13M

Select item 341667815.

Bioactivity of Samsum ant (Pachycondyla sennaarensis) venom against lipopolysaccharides through antioxidant and upregulation of Akt1 signaling in rats

Hossam Ebaid, Mohamed Al-Khalifa, Ahmed M Isa, Saad Gadoa

Lipids Health Dis. 2012; 11: 93. Published online 2012 Jul 23. doi: 10.1186/1476-511X-11-93

PMCID:: PMC3416678

Abstract Article PDF–1.1M

Select item 340838416.

Coculture with hematopoietic stem cells protects cardiomyocytes against apoptosis via paracrine activation of AKT

Mark Rosenberg, Matthias Lutz, Constantin Kühl, Rainer Will, Volker Eckstein, Jutta Krebs, Hugo A Katus, Norbert Frey

J Transl Med. 2012; 10: 115. Published online 2012 Jun 6. doi: 10.1186/1479-5876-10-115

PMCID:: PMC3408384

Abstract Article PDF–1.9M

Select item 335378717.

Mitochondrial Akt-regulated mitochondrial apoptosis signaling in cardiac muscle cells

Ching-Chieh Su, Jia-Ying Yang, Hsin-Ban Leu, Yumay Chen, Ping H. Wang

Am J Physiol Heart Circ Physiol. 2012 Feb 1; 302(3): H716–H723. Published online 2011 Nov 11. doi: 10.1152/ajpheart.00455.2011

PMCID:: PMC3353787

Abstract Article

Select item 328170818.

Human Umbilical Cord Blood Cells Protect Oligodendrocytes from Brain Ischemia through Akt Signal Transduction

Derrick D. Rowe, Christopher C. Leonardo, Jesus A. Recio, Lisa A. Collier, Alison E. Willing, Keith R. Pennypacker

J Biol Chem. 2012 Feb 3; 287(6): 4177–4187. Published online 2011 Dec 12. doi: 10.1074/jbc.M111.296434

PMCID:: PMC3281708

Abstract Article PDF–3.9M

Select item 318217819.

Impaired Striatal Akt Signaling Disrupts Dopamine Homeostasis and Increases Feeding

Nicole Speed, Christine Saunders, Adeola R. Davis, W. Anthony Owens, Heinrich J. G. Matthies, Sanaz Saadat, Jack P. Kennedy, Roxanne A. Vaughan, Rachael L. Neve, Craig W. Lindsley, Scott J. Russo, Lynette C. Daws, Kevin D. Niswender1, Aurelio Galli

PLoS One. 2011; 6(9): e25169. Published online 2011 Sep 28. doi: 10.1371/journal.pone.0025169