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Items: 1 to 20 of 28

1.
Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics
Thu Ly, Christopher T. Pappas, Dylan Johnson, William Schlecht, Mert Colpan, Vitold E. Galkin, Carol C. Gregorio, Wen-Ji Dong, Alla S. Kostyukova
Mol Biol Cell. 2019 Jan 15; 30(2): 268–281. doi: 10.1091/mbc.E18-06-0406
PMCID:
PMC6589558
ArticlePDF–2.6M
2.
Transmission of Stability Information through the N-domain of Tropomyosin Is Interrupted by a Stabilizing Mutation (A109L) in the Hydrophobic Core of the Stability Control Region (Residues 97–118)
J. Paul Kirwan, Robert S. Hodges
J Biol Chem. 2014 Feb 14; 289(7): 4356–4366. Published online 2013 Dec 20. doi: 10.1074/jbc.M113.507236
PMCID:
PMC3924298
ArticlePDF–1.1M
3.
Regulation of actin-myosin interaction by conserved periodic sites of tropomyosin
Bipasha Barua, Donald A. Winkelmann, Howard D. White, Sarah E. Hitchcock-DeGregori
Proc Natl Acad Sci U S A. 2012 Nov 6; 109(45): 18425–18430. Published online 2012 Oct 3. doi: 10.1073/pnas.1212754109
PMCID:
PMC3494946
ArticlePDF–971K
4.
The role of tropomyosin domains in cooperative activation of the actin-myosin interaction
Yusuke Oguchi, Junji Ishizuka, Sarah E. Hitchcock-DeGregori, Shin’ichi Ishiwata, Masataka Kawai
J Mol Biol. Author manuscript; available in PMC 2012 Dec 16.
Published in final edited form as: J Mol Biol. 2011 Dec 16; 414(5): 667–680. Published online 2011 Oct 20. doi: 10.1016/j.jmb.2011.10.026
PMCID:
PMC3230701
ArticlePDF–2.4M
5.
Phosphorylation of Tropomyosin Extends Cooperative Binding of Myosin Beyond a Single Regulatory Unit
Vijay S. Rao, Ellisha N. Marongelli, William H. Guilford
Cell Motil Cytoskeleton. Author manuscript; available in PMC 2009 Oct 29.
Published in final edited form as: Cell Motil Cytoskeleton. 2009 Jan; 66(1): 10–23. doi: 10.1002/cm.20321
PMCID:
PMC2770177
ArticlePDF–2.0M
6.
Effect of actin C-terminal modification on tropomyosin isoforms binding and thin filament regulation
Radosław Skórzewski, Małgorzata Śliwińska, Danuta Borys, Apolinary Sobieszek, Joanna Moraczewska
Biochim Biophys Acta. 2009 Feb; 1794(2): 237–243. doi: 10.1016/j.bbapap.2008.10.014
PMCID:
PMC2628472
Article
7.
A nonsense exon in the Tpm1 gene is silenced by hnRNP H and F
Joel L. Coles, Martina Hallegger, Christopher W.J. Smith
RNA. 2009 Jan; 15(1): 33–43. doi: 10.1261/rna.1225209
PMCID:
PMC2612778
ArticlePDF–707K
8.
Structure of the mid-region of tropomyosin: Bending and binding sites for actin
Jerry H. Brown, Zhaocai Zhou, Ludmilla Reshetnikova, Howard Robinson, Rama D. Yammani, Larry S. Tobacman, Carolyn Cohen
Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52): 18878–18883. Published online 2005 Dec 19. doi: 10.1073/pnas.0509269102
PMCID:
PMC1323185
ArticlePDF–818K
9.
The rat alpha-tropomyosin gene generates a minimum of six different mRNAs coding for striated, smooth, and nonmuscle isoforms by alternative splicing.
D F Wieczorek, C W Smith, B Nadal-Ginard
Mol Cell Biol. 1988 Feb; 8(2): 679–694. doi: 10.1128/mcb.8.2.679
PMCID:
PMC363194
SummaryPage BrowsePDF–4.0M
10.
Three novel brain tropomyosin isoforms are expressed from the rat alpha-tropomyosin gene through the use of alternative promoters and alternative RNA processing.
J P Lees-Miller, L O Goodwin, D M Helfman
Mol Cell Biol. 1990 Apr; 10(4): 1729–1742. doi: 10.1128/mcb.10.4.1729
PMCID:
PMC362279
SummaryPage BrowsePDF–2.7M
11.
A splicing silencer that regulates smooth muscle specific alternative splicing is active in multiple cell types
Natalia Gromak, Christopher W. J. Smith
Nucleic Acids Res. 2002 Aug 15; 30(16): 3548–3557. doi: 10.1093/nar/gkf480
PMCID:
PMC134246
ArticlePDF–349K
12.
CaMKII regulates the proteins TPM1 and MYOM2 and promotes diacetylmorphine-induced abnormal cardiac rhythms
Min Ji, Liping Su, Li Liu, Mengjie Zhuang, Jinling Xiao, Yaling Guan, Sensen Zhu, Lijuan Ma, Hongwei Pu
Sci Rep. 2023; 13: 5827. Published online 2023 Apr 10. doi: 10.1038/s41598-023-32941-6
PMCID:
PMC10085977
ArticlePDF–4.7M
13.
Conserved Asp-137 Is Important for both Structure and Regulatory Functions of Cardiac α-Tropomyosin (α-TM) in a Novel Transgenic Mouse Model Expressing α-TM-D137L
Sumeyye Yar, Shamim A. K. Chowdhury, Robert T. Davis, 3rd, Minae Kobayashi, Michelle M. Monasky, Sudarsan Rajan, Beata M. Wolska, Vadim Gaponenko, Tomoyoshi Kobayashi, David F. Wieczorek, R. John Solaro
J Biol Chem. 2013 Jun 7; 288(23): 16235–16246. Published online 2013 Apr 22. doi: 10.1074/jbc.M113.458695
PMCID:
PMC3675563
ArticlePDF–1.6M
14.
In Vitro formation and characterization of the skeletal muscle α·β Tropomyosin heterodimers
Athanasia Kalyva, Anja Schmidtmann, Michael A. Geeves
Biochemistry. Author manuscript; available in PMC 2013 Jan 3.
Published in final edited form as: Biochemistry. 2012 Aug 14; 51(32): 6388–6399. Published online 2012 Aug 3. doi: 10.1021/bi300340r
PMCID:
PMC3535570
ArticlePDF–880K
15.
Combinatorial Effects of Double Cardiomyopathy Mutant Alleles in Rodent Myocytes: A Predictive Cellular Model of Myofilament Dysregulation in Disease
Jennifer Davis, Joseph M. Metzger
PLoS One. 2010; 5(2): e9140. Published online 2010 Feb 10. doi: 10.1371/journal.pone.0009140
PMCID:
PMC2818843
ArticlePDF–1.0M
16.
Structure and Tropomyosin Binding Properties of the N-Terminal Capping Domain of Tropomodulin 1
Norma J. Greenfield, Alla S. Kostyukova, Sarah E. Hitchcock-DeGregori
Biophys J. 2005 Jan; 88(1): 372–383. Published online 2004 Oct 8. doi: 10.1529/biophysj.104.051128
PMCID:
PMC1305014
ArticlePDF–452K
17.
A Periodic Pattern of Evolutionarily Conserved Basic and Acidic Residues Constitutes the Binding Interface of Actin-Tropomyosin
Bipasha Barua, Patricia M. Fagnant, Donald A. Winkelmann, Kathleen M. Trybus, Sarah E. Hitchcock-DeGregori
J Biol Chem. 2013 Apr 5; 288(14): 9602–9609. Published online 2013 Feb 18. doi: 10.1074/jbc.M113.451161
PMCID:
PMC3617264
ArticlePDF–1.7M
18.
Temperature-Dependence of Isometric Tension and Cross-Bridge Kinetics of Cardiac Muscle Fibers Reconstituted with a Tropomyosin Internal Deletion Mutant
Xiaoying Lu, Larry S. Tobacman, Masataka Kawai
Biophys J. 2006 Dec 1; 91(11): 4230–4240. Published online 2006 Sep 15. doi: 10.1529/biophysj.106.084608
PMCID:
PMC1635655
ArticlePDF–240K
19.
Extracellular Signal-regulated Kinase Mediates Phosphorylation of Tropomyosin-1 to Promote Cytoskeleton Remodeling in Response to Oxidative Stress: Impact on Membrane Blebbing
François Houle, Simon Rousseau, Nick Morrice, Mario Luc, Sébastien Mongrain, Christopher E. Turner, Sakae Tanaka, Pierre Moreau, Jacques Huot
Mol Biol Cell. 2003 Apr; 14(4): 1418–1432. doi: 10.1091/mbc.E02-04-0235
PMCID:
PMC153111
ArticlePDF–1.1M
20.
Specificity of dimer formation in tropomyosins: influence of alternatively spliced exons on homodimer and heterodimer assembly.
M Gimona, A Watakabe, D M Helfman
Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21): 9776–9780. doi: 10.1073/pnas.92.21.9776
PMCID:
PMC40885
SummaryPage BrowsePDF–1.8M

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