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Items: 17

1.
Proprotein Convertase 1/3 (PC1/3) in the Rat Alveolar Macrophage Cell Line NR8383: Localization, Trafficking and Effects on Cytokine Secretion
Hugo Gagnon, Sarah Refaie, Sandra Gagnon, Roxane Desjardins, Michel Salzet, Robert Day
PLoS One. 2013; 8(4): e61557. Published online 2013 Apr 24. doi: 10.1371/journal.pone.0061557
PMCID:
PMC3634814
AbstractArticlePDF–8.8M
2.
Transplantation of PC1/3-Expressing α-cells Improves Glucose Handling and Cold Tolerance in Leptin-resistant Mice
Rhonda D Wideman, Sarah L Gray, Scott D Covey, Gene C Webb, Timothy J Kieffer
Mol Ther. 2009 Jan; 17(1): 191–198. Published online 2008 Oct 21. doi: 10.1038/mt.2008.219
PMCID:
PMC2834990
AbstractArticlePDF–1.3M
3.
DIFFERENTIAL REGULATION OF PC1/3, PC2 AND PHOSPHORYLATED CREB BY SHORT-TERM AND LONG-TERM MORPHINE TREATMENT: IMPLICATIONS FOR UNDERSTANDING THE “SWITCH” TO OPIATE ADDICTION
VERONICA PAEZ ESPINOSA, YANJUN LIU, MONICA FERRINI, ADRIAN ANGHEL, YING NIE, PINKY V. TRIPATHI, RENE PORCHE, ERIK JANSEN, RONALD C. STUART, EDUARDO A. NILLNI, KABIRULLAH LUTFY, THEODORE C. FRIEDMAN
Neuroscience. Author manuscript; available in PMC 2009 Oct 15.
Published in final edited form as: Neuroscience. 2008 Oct 15; 156(3): 788–799. Published online 2008 Aug 9. doi: 10.1016/j.neuroscience.2008.07.063
PMCID:
PMC2596639
AbstractArticlePDF–1.3M
4.
The Identification of Potential Factors Associated with the Development of Type 2 Diabetes: A Quantitative Proteomics Approach
Hongfang Lu, Ying Yang, Emma M. Allister, Nadeeja Wijesekara, Michael B. Wheeler
Mol Cell Proteomics. 2008 Aug; 7(8): 1434–1451. doi: 10.1074/mcp.M700478-MCP200
PMCID:
PMC2500228
AbstractArticlePDF–1.2M
5.
The transmembrane domain of the prohormone convertase PC3: A key motif for targeting to the regulated secretory pathway
Hong Lou, Angela M. Smith, Leigh C. Coates, Niamh X. Cawley, Y. Peng Loh, Nigel P. Birch
Mol Cell Endocrinol. Author manuscript; available in PMC 2008 Mar 15.
Published in final edited form as: Mol Cell Endocrinol. 2007 Mar 15; 267(1-2): 17–25. Published online 2006 Dec 16. doi: 10.1016/j.mce.2006.11.011
PMCID:
PMC1892588
AbstractArticlePDF–435K
6.
Improving function and survival of pancreatic islets by endogenous production of glucagon-like peptide 1 (GLP-1)
Rhonda D. Wideman, Irene L. Y. Yu, Travis D. Webber, C. Bruce Verchere, James D. Johnson, Anthony T. Cheung, Timothy J. Kieffer
Proc Natl Acad Sci U S A. 2006 Sep 5; 103(36): 13468–13473. Published online 2006 Aug 28. doi: 10.1073/pnas.0600655103
PMCID:
PMC1569187
AbstractArticlePDF–1.9M
7.
Increased secretory demand rather than a defect in the proinsulin conversion mechanism causes hyperproinsulinemia in a glucose-infusion rat model of non-insulin-dependent diabetes mellitus.
C Alarcón, J L Leahy, G T Schuppin, C J Rhodes
J Clin Invest. 1995 Mar; 95(3): 1032–1039. doi: 10.1172/JCI117748
PMCID:
PMC441437
SummaryPage BrowsePDF–2.4M
8.
Mutational analysis of predicted interactions between the catalytic and P domains of prohormone convertase 3 (PC3/PC1)
Kazuya Ueda, Gregory M. Lipkind, An Zhou, Xiaorong Zhu, Andrey Kuznetsov, Louis Philipson, Paul Gardner, Chunling Zhang, Donald F. Steiner
Proc Natl Acad Sci U S A. 2003 May 13; 100(10): 5622–5627. Published online 2003 Apr 29. doi: 10.1073/pnas.0631617100
PMCID:
PMC156251
AbstractArticlePDF–572K
9.
The proprotein convertase PC1/3 regulates TLR9 trafficking and the associated signaling pathways
M. Duhamel, F. Rodet, A. N. Murgoci, R. Desjardins, H. Gagnon, M. Wisztorski, I. Fournier, R. Day, M. Salzet
Sci Rep. 2016; 6: 19360. Published online 2016 Jan 18. doi: 10.1038/srep19360
PMCID:
PMC4725977
AbstractArticlePDF–1.9M
10.
Decreased Immunoreactivity of the Polypeptide Precursor Pro-Opiomelanocortin (POMC) and the Prohormone Convertase PC1/3 after Chronic Ethanol Exposure in Sprague-Dawley Rats
Montserrat Navarro, Inmaculada Cubero, Todd E. Thiele
Alcohol Clin Exp Res. Author manuscript; available in PMC 2014 Mar 1.
Published in final edited form as: Alcohol Clin Exp Res. 2013 Mar; 37(3): 399–406. Published online 2012 Oct 10. doi: 10.1111/j.1530-0277.2012.01951.x
PMCID:
PMC3543756
AbstractArticlePDF–2.1M
11.
Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease
Jimmy D. Dikeakos, Paola Di Lello, Marie-Josée Lacombe, Rodolfo Ghirlando, Pascale Legault, Timothy L. Reudelhuber, James G. Omichinski
Proc Natl Acad Sci U S A. 2009 May 5; 106(18): 7408–7413. Published online 2009 Apr 17. doi: 10.1073/pnas.0809576106
PMCID:
PMC2678656
AbstractArticlePDF–572K
12.
MafA controls Genes implicated in Insulin Biosynthesis and Secretion
H. Wang, T. Brun, C. B. Wollheim, K. Kataoka, A. Sharma
Diabetologia. Author manuscript; available in PMC 2008 Jan 14.
Published in final edited form as: Diabetologia. 2007 Feb; 50(2): 348–358. Published online 2006 Dec 6. doi: 10.1007/s00125-006-0490-2
PMCID:
PMC2196442
AbstractArticlePDF–2.4M
13.
Regulation of hypothalamic prohormone convertases 1 and 2 and effects on processing of prothyrotropin-releasing hormone
Vanesa C. Sanchez, Jorge Goldstein, Ronald C. Stuart, Virginia Hovanesian, Lihong Huo, Heike Munzberg, Theodore C. Friedman, Christian Bjorbaek, Eduardo A. Nillni
J Clin Invest. 2004 Aug 1; 114(3): 357–369. doi: 10.1172/JCI21620
PMCID:
PMC484982
AbstractArticlePDF–1.1M
14.
The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: implications for early maturation of proteolytic processing capacity
M Zheng, RD Streck, RE Scott, NG Seidah, JE Pintar
J Neurosci. 1994 Aug 1; 14(8): 4656–4673. doi: 10.1523/JNEUROSCI.14-08-04656.1994
PMCID:
PMC6577180
AbstractPDF–8.1M
15.
Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects
Xiaorong Zhu, An Zhou, Arunangsu Dey, Christina Norrbom, Raymond Carroll, Chunling Zhang, Virginie Laurent, Iris Lindberg, Randi Ugleholdt, Jens J. Holst, Donald F. Steiner
Proc Natl Acad Sci U S A. 2002 Aug 6; 99(16): 10293–10298. Published online 2002 Jul 26. doi: 10.1073/pnas.162352599
PMCID:
PMC124907
AbstractArticlePDF–410K
16.
Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2.
S Benjannet, N Rondeau, L Paquet, A Boudreault, C Lazure, M Chrétien, N G Seidah
Biochem J. 1993 Sep 15; 294(Pt 3): 735–743. doi: 10.1042/bj2940735
PMCID:
PMC1134524
SummaryPage BrowsePDF–2.5M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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