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Select item 90123201.

Melanocortin-4 Receptor Signaling in the Central Amygdala Mediates Chronic Inflammatory Pain Effects on Nociception

Nathan M. Sharfman, Leslie K. Kelley, Maria E. Secci, Nicholas W. Gilpin

Neuropharmacology. Author manuscript; available in PMC 2023 Jun 1.

Published in final edited form as: Neuropharmacology. 2022 Jun 1; 210: 109032. Published online 2022 Mar 16. doi: 10.1016/j.neuropharm.2022.109032

PMCID:: PMC9012320

Abstract Article PDF–1.4M

Select item 64625072.

Melanocortin type 4 receptor–mediated inhibition of A-type K⁺ current enhances sensory neuronal excitability and mechanical pain sensitivity in rats

Yuan Zhang, Dongsheng Jiang, Hua Li, Yufang Sun, Xinghong Jiang, Shan Gong, Zhiyuan Qian, Jin Tao

J Biol Chem. 2019 Apr 5; 294(14): 5496–5507. Published online 2019 Feb 11. doi: 10.1074/jbc.RA118.006894

PMCID:: PMC6462507

Abstract Article PDF–2.4M

Select item 64160583.

ROLE OF MELANOCORTIN 4 RECEPTOR IN HYPERTENSION INDUCED BY CHRONIC INTERMITTENT HYPOXIA

Jussara M. do Carmo, Alexandre A. da Silva, Sydney P. Moak, Fernanda S. da Silva, Frank T. Spradley, John E. Hall

Acta Physiol (Oxf) Author manuscript; available in PMC 2020 Apr 1.

Published in final edited form as: Acta Physiol (Oxf). 2019 Apr; 225(4): e13222. Published online 2018 Dec 23. doi: 10.1111/apha.13222

PMCID:: PMC6416058

Abstract Article PDF–1.0M

Select item 47489684.

Role of hindbrain melanocortin-4 receptor activity in controlling cardiovascular and metabolic functions in spontaneously hypertensive rats

Jussara M. do Carmo, Alexandre A. da Silva, John E. Hall

J Hypertens. Author manuscript; available in PMC 2016 Feb 10.

Published in final edited form as: J Hypertens. 2015 Jun; 33(6): 1201–1206. doi: 10.1097/HJH.0000000000000530

PMCID:: PMC4748968

Abstract Article PDF–2.0M

Select item 43988555.

Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats

Rodrigo Maranon, Roberta Lima, Frank T. Spradley, Jussara M. do Carmo, Howei Zhang, Andrew D. Smith, Elizabeth Bui, R. Lucas Thomas, Mohadetheh Moulana, John E. Hall, Joey P. Granger, Jane F. Reckelhoff

Am J Physiol Regul Integr Comp Physiol. 2015 Apr 15; 308(8): R708–R713. Published online 2015 Feb 18. doi: 10.1152/ajpregu.00411.2014

PMCID:: PMC4398855

Abstract Article

Select item 41208416.

LOSS OF MELANOCORTIN-4 RECEPTOR FUNCTION ATTENUATES HPA RESPONSES TO PSYCHOLOGICAL STRESS

Karen K. Ryan, Joram D. Mul, Christoffer Clemmensen, Ann E. Egan, Denovan P. Begg, Kristen Halcomb, Randy J. Seeley, James P. Herman, Yvonne M. Ulrich-Lai

Psychoneuroendocrinology. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Psychoneuroendocrinology. 2014 Apr; 42: 98–105. Published online 2014 Jan 22. doi: 10.1016/j.psyneuen.2014.01.010

PMCID:: PMC4120841

Abstract Article PDF–2.1M

Select item 38714617.

Vascular effects of deletion of melanocortin-4 receptors in rats

David W Stepp, Christabell C Osakwe, Eric J Belin de Chantemele, James D Mintz

Physiol Rep. 2013 Nov; 1(6): e00146. Published online 2013 Nov 13. doi: 10.1002/phy2.146

PMCID:: PMC3871461

Abstract Article PDF–705K

Select item 37613408.

Activation of melanocortin receptors in the intermediolateral cell column of the upper thoracic cord elicits tachycardia in the rat

Masamitsu Iwasa, Kazumi Kawabe, Hreday N. Sapru

Am J Physiol Heart Circ Physiol. 2013 Sep 15; 305(6): H885–H893. Published online 2013 Jul 5. doi: 10.1152/ajpheart.00443.2013

PMCID:: PMC3761340

Abstract Article

Select item 37084659.

Adeno-associated virus-mediated knockdown of melanocortin-4 receptor in the paraventricular nucleus of the hypothalamus promotes high-fat diet-induced hyperphagia and obesity

Jacob C Garza, Chung Sub Kim, Jing Liu, Wei Zhang, Xin-Yun Lu

J Endocrinol. Author manuscript; available in PMC 2013 Jul 11.

Published in final edited form as: J Endocrinol. 2008 Jun; 197(3): 471–482. doi: 10.1677/JOE-08-0009

PMCID:: PMC3708465

Abstract Article PDF–2.0M

Select item 370846110.

Melanocortin-4 receptor in the medial amygdala regulates emotional stress-induced anxiety-like behaviour, anorexia and corticosterone secretion

Jing Liu, Jacob C. Garza, Wei Li, Xin-Yun Lu

Int J Neuropsychopharmacol. Author manuscript; available in PMC 2013 Jul 11.

Published in final edited form as: Int J Neuropsychopharmacol. 2013 Feb; 16(1): 105–120. Published online 2011 Dec 16. doi: 10.1017/S146114571100174X

PMCID:: PMC3708461

Abstract Article PDF–2.3M

Select item 368187211.

Angiotensin-converting enzyme inhibition reduces food intake, weight gain and improves glucose tolerance in melanocortin-4 receptor deficient female rats

Joram D. Mul, Randy J. Seeley, Stephen C. Woods, Denovan P. Begg

Physiol Behav. Author manuscript; available in PMC 2014 Sep 10.

Published in final edited form as: Physiol Behav. 2013 Sep 10; 121: 10.1016/j.physbeh.2013.01.013. Published online 2013 Feb 13. doi: 10.1016/j.physbeh.2013.01.013

PMCID:: PMC3681872

Abstract Article PDF–749K

Select item 340456212.

Effect of vertical sleeve gastrectomy in melanocortin receptor 4-deficient rats

Joram D. Mul, Denovan P. Begg, Suzanne I. M. Alsters, Gijs van Haaften, Karen J. Duran, David A. D'Alessio, Carel W. le Roux, Stephen C. Woods, Darleen A. Sandoval, Alexandra I. F. Blakemore, Edwin Cuppen, Mieke M. van Haelst, Randy J. Seeley

Am J Physiol Endocrinol Metab. 2012 Jul 1; 303(1): E103–E110. Published online 2012 Apr 24. doi: 10.1152/ajpendo.00159.2012

PMCID:: PMC3404562

Abstract Article

Select item 320246513.

A Pharmacologically Active Monoclonal Antibody against the Human Melanocortin-4 Receptor: Effectiveness After Peripheral and Central Administration

Jean-Christophe Peter, Anne-Catherine Lecourt, Marjorie Weckering, Géraldine Zipfel, Michael L. Niehoff, William A. Banks, Karl G. Hofbauer

J Pharmacol Exp Ther. 2010 May; 333(2): 478–490. doi: 10.1124/jpet.109.163279

PMCID:: PMC3202465

Abstract Article PDF–2.5M

Select item 288727314.

Genetic and pharmacologic blockade of central melanocortin signaling attenuates cardiac cachexia in rodent models of heart failure

Jarrad M Scarlett, Darren D Bowe, Xinxia Zhu, Ayesha K Batra, Wilmon F Grant, Daniel L Marks

J Endocrinol. 2010 Jul; 206(1): 121–130. Prepublished online 2010 Apr 6. doi: 10.1677/JOE-09-0397

PMCID:: PMC2887273

Abstract Article PDF–171K

Select item 268129715.

Presynaptic Melanocortin-4 Receptors on Vagal Afferent Fibers Modulate the Excitability of Rat Nucleus Tractus Solitarius Neurons

Shuxia Wan, Kirsteen N. Browning, F. Holly Coleman, Gregory Sutton, Hiyuan Zheng, Andrew Butler, Hans-Rudolf Berthoud, R. Alberto Travagli

J Neurosci. 2008 May 7; 28(19): 4957–4966. doi: 10.1523/JNEUROSCI.5398-07.2008

PMCID:: PMC2681297

Abstract Article PDF–404K

Select item 558149216.

Adolescent Alcohol Exposure-Induced Changes in Alpha-Melanocyte Stimulating Hormone and Neuropeptide Y Pathways via Histone Acetylation in the Brain During Adulthood

Dadasaheb M Kokare, Evan J Kyzar, Huaibo Zhang, Amul J Sakharkar, Subhash C Pandey

Int J Neuropsychopharmacol. 2017 Sep; 20(9): 758–768. Published online 2017 May 31. doi: 10.1093/ijnp/pyx041

PMCID:: PMC5581492

Abstract Article PDF–9.3M

Select item 513057617.

Nitric oxide synthase-mediated blood pressure regulation in obese melanocortin-4 receptor-deficient pregnant rats

Frank T. Spradley, Jennifer M. Sasser, Jacqueline B. Musall, Jennifer C. Sullivan, Joey P. Granger

Am J Physiol Regul Integr Comp Physiol. 2016 Nov 1; 311(5): R851–R857. Published online 2016 Aug 15. doi: 10.1152/ajpregu.00285.2016

PMCID:: PMC5130576

Abstract Article

Select item 505467918.

Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats

Panpan You, Handan Hu, Yuting Chen, Yongliang Zhao, Yiqing Yang, Tongtong Wang, Roumei Xing, Yanjiao Shao, Wen Zhang, Dali Li, Huaqing Chen, Mingyao Liu

Sci Rep. 2016; 6: 34938. Published online 2016 Oct 7. doi: 10.1038/srep34938

PMCID:: PMC5054679

Abstract Article PDF–2.0M

Select item 374291919.

Melanocortin Signaling in the Brainstem Influences Vagal Outflow to the Stomach

Janell Richardson, Maureen T. Cruz, Usnish Majumdar, Amanda Lewin, Kathryn A. Kingsbury, Ghazaul Dezfuli, Stefano Vicini, Joseph G. Verbalis, Kenneth L. Dretchen, Richard A. Gillis, Niaz Sahibzada

J Neurosci. 2013 Aug 14; 33(33): 13286–13299. doi: 10.1523/JNEUROSCI.0780-13.2013