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Items: 1 to 20 of 56

1.
Identification of a novel nucleolar protein complex required for mitotic chromosome segregation through centromeric accumulation of Aurora B
Akiko Fujimura, Yuki Hayashi, Kazashi Kato, Yuichiro Kogure, Mutsuro Kameyama, Haruka Shimamoto, Hiroaki Daitoku, Akiyoshi Fukamizu, Toru Hirota, Keiji Kimura
Nucleic Acids Res. 2020 Jul 9; 48(12): 6583–6596. Published online 2020 Jun 1. doi: 10.1093/nar/gkaa449
PMCID:
PMC7337965
AbstractArticlePDF–4.0M
2.
Human nucleolar protein 7 (NOL7) is required for early pre-rRNA accumulation and pre-18S rRNA processing
Mason A. McCool, Carson J. Bryant, Hannah Huang, Lisa M. Ogawa, Katherine I. Farley-Barnes, Samuel B. Sondalle, Laura Abriola, Yulia V. Surovtseva, Susan J. Baserga
RNA Biol. 2023; 20(1): 257–271. Published online 2023 May 29. doi: 10.1080/15476286.2023.2217392
PMCID:
PMC10228412
AbstractArticlePDF–2.8M
3.
NOL11, Implicated in the Pathogenesis of North American Indian Childhood Cirrhosis, Is Required for Pre-rRNA Transcription and Processing
Emily F. Freed, José-Luis Prieto, Kathleen L. McCann, Brian McStay, Susan J. Baserga
PLoS Genet. 2012 Aug; 8(8): e1002892. Published online 2012 Aug 16. doi: 10.1371/journal.pgen.1002892
PMCID:
PMC3420923
AbstractArticlePDF–2.3M
4.
GABRA1 and STXBP1: Novel genetic causes of Dravet syndrome
Gemma L. Carvill, Sarah Weckhuysen, Jacinta M. McMahon, Corinna Hartmann, Rikke S. Møller, Helle Hjalgrim, Joseph Cook, Eileen Geraghty, Brian J. O’Roak, Steve Petrou, Alison Clarke, Deepak Gill, Lynette G. Sadleir, Hiltrud Muhle, Sarah von Spiczak, Marina Nikanorova, Bree L. Hodgson, Elena V. Gazina, Arvid Suls, Jay Shendure, Leanne M. Dibbens, Peter De Jonghe, Ingo Helbig, Samuel F. Berkovic, Ingrid E. Scheffer, Heather C. Mefford
Neurology. 2014 Apr 8; 82(14): 1245–1253. doi: 10.1212/WNL.0000000000000291
PMCID:
PMC4001207
AbstractArticlePDF–667K
5.
Functional Proteomic Analysis of Human Nucleolus
Alexander Scherl, Yohann Couté, Catherine Déon, Aleth Callé, Karine Kindbeiter, Jean-Charles Sanchez, Anna Greco, Denis Hochstrasser, Jean-Jacques Diaz
Mol Biol Cell. 2002 Nov; 13(11): 4100–4109. doi: 10.1091/mbc.E02-05-0271
PMCID:
PMC133617
AbstractArticlePDF–369K
6.
Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage
Sarah J. Hill, Thomas Rolland, Guillaume Adelmant, Xianfang Xia, Matthew S. Owen, Amélie Dricot, Travis I. Zack, Nidhi Sahni, Yves Jacob, Tong Hao, Kristine M. McKinney, Allison P. Clark, Deepak Reyon, Shengdar Q. Tsai, J. Keith Joung, Rameen Beroukhim, Jarrod A. Marto, Marc Vidal, Suzanne Gaudet, David E. Hill, David M. Livingston
Genes Dev. 2014 Sep 1; 28(17): 1957–1975. doi: 10.1101/gad.241620.114
PMCID:
PMC4197947
AbstractArticlePDF–2.4M
7.
FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3
Kamila M. Jozwik, Igor Chernukhin, Aurelien A. Serandour, Sankari Nagarajan, Jason S. Carroll
Cell Rep. 2016 Dec 6; 17(10): 2715–2723. Published online 2016 Dec 6. doi: 10.1016/j.celrep.2016.11.028
PMCID:
PMC5177601
AbstractArticlePDF–2.9M
8.
SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response
Lei-Lei Chen, Huai-Peng Lin, Wen-Jie Zhou, Chen-Xi He, Zhi-Yong Zhang, Zhou-Li Cheng, Jun-Bin Song, Peng Liu, Xin-Yu Chen, Yu-Kun Xia, Xiu-Fei Chen, Ren-Qiang Sun, Jing-Ye Zhang, Yi-Ping Sun, Lei Song, Bing-Jie Liu, Rui-Kai Du, Chen Ding, Fei Lan, Sheng-Lin Huang, Feng Zhou, Suling Liu, Yue Xiong, Dan Ye, Kun-Liang Guan
Cell Rep. Author manuscript; available in PMC 2019 Jan 3.
Published in final edited form as: Cell Rep. 2018 Nov 6; 25(6): 1485–1500.e4. doi: 10.1016/j.celrep.2018.10.028
PMCID:
PMC6317994
AbstractArticlePDF–1.4M
9.
Genome-wide CRISPR-Cas9 screen identifies leukemia-specific dependence on a pre-mRNA metabolic pathway regulated by DCPS
Takuji Yamauchi, Takeshi Masuda, Matthew C. Canver, Michael Seiler, Yuichiro Semba, Mohammad Shboul, Mohammed Al-Raqad, Manami Maeda, Vivien A. C. Schoonenberg, Mitchel A. Cole, Claudio Macias-Trevino, Yuichi Ishikawa, Qiuming Yao, Michitaka Nakano, Fumio Arai, Stuart H. Orkin, Bruno Reversade, Silvia Buonamici, Luca Pinello, Koichi Akashi, Daniel E. Bauer, Takahiro Maeda
Cancer Cell. Author manuscript; available in PMC 2019 Mar 12.
Published in final edited form as: Cancer Cell. 2018 Mar 12; 33(3): 386–400.e5. Published online 2018 Feb 22. doi: 10.1016/j.ccell.2018.01.012
PMCID:
PMC5849534
AbstractArticlePDF–1.1M
10.
The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA
Benjamin A Diner, Tuo Li, Todd M Greco, Marni S Crow, John A Fuesler, Jennifer Wang, Ileana M Cristea
Mol Syst Biol. 2015 Feb; 11(2): 787. Published online 2015 Feb 9. doi: 10.15252/msb.20145808
PMCID:
PMC4358659
AbstractArticlePDF–3.6M
11.
Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression
Benjamin A. Diner, Krystal K. Lum, Aaron Javitt, Ileana M. Cristea
Mol Cell Proteomics. 2015 Sep; 14(9): 2341–2356. Published online 2015 Feb 18. doi: 10.1074/mcp.M114.047068
PMCID:
PMC4563720
AbstractArticlePDF–2.8M
12.
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
Jiang Ren, Shuai Wang, Zhi Zong, Ting Pan, Sijia Liu, Wei Mao, Huizhe Huang, Xiaohua Yan, Bing Yang, Xin He, Fangfang Zhou, Long Zhang
Nat Commun. 2024; 15: 244. Published online 2024 Jan 4. doi: 10.1038/s41467-023-44502-6
PMCID:
PMC10764958
AbstractArticlePDF–4.4M
13.
ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold
Wenjing Yang, Beili Wang, Qian Yu, Te Liu, Tong Li, Tongtong Tian, Anli Jin, Lin Ding, Wei Chen, Hao Wang, Jingrong Xian, Baishen Pan, Jian Zhou, Jia Fan, Xinrong Yang, Wei Guo
Theranostics. 2022; 12(14): 6189–6206. Published online 2022 Aug 21. doi: 10.7150/thno.72134
PMCID:
PMC9475462
AbstractArticlePDF–4.6M
14.
The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing
Yingxiao Chen, Yanping Li, Roselyn S Dai, Jonathan C Savage, Ujwal Shinde, John Klimek, Larry L David, Emma A Young, Markus Hafner, Rosalie C Sears, Xiao-Xin Sun, Mu-Shui Dai
Nucleic Acids Res. 2023 May 8; 51(8): 3934–3949. Published online 2023 Mar 13. doi: 10.1093/nar/gkad140
PMCID:
PMC10164564
AbstractArticlePDF–3.8M
15.
AMPK, a key regulator of metabolism and autophagy, is activated by lysosomal damage via a novel galectin-directed ubiquitin signal transduction system
Jingyue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers, Seong Won Choi, Yuexi Gu, Mark Zbinden, Mark R. Burge, Graham Timmins, Kenneth Hallows, Christian Behrends, Vojo Deretic
Mol Cell. Author manuscript; available in PMC 2021 Mar 5.
Published in final edited form as: Mol Cell. 2020 Mar 5; 77(5): 951–969.e9. Published online 2020 Jan 28. doi: 10.1016/j.molcel.2019.12.028
PMCID:
PMC7785494
AbstractArticlePDF–2.9M
16.
CHK2–BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly
Norman Ertych, Ailine Stolz, Oliver Valerius, Gerhard H. Braus, Holger Bastians
Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7): 1817–1822. Published online 2016 Feb 1. doi: 10.1073/pnas.1525129113
PMCID:
PMC4763769
AbstractArticlePDF–1.3M
17.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
AbstractArticlePDF–3.6M
18.
The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation
Kaushik Bhattacharya, Lorenz Weidenauer, Tania Morán Luengo, Ellis C. Pieters, Pablo C. Echeverría, Lilia Bernasconi, Diana Wider, Yashar Sadian, Margreet B. Koopman, Matthieu Villemin, Christoph Bauer, Stefan G. D. Rüdiger, Manfredo Quadroni, Didier Picard
Nat Commun. 2020; 11: 5975. Published online 2020 Nov 25. doi: 10.1038/s41467-020-19783-w
PMCID:
PMC7688965
AbstractArticlePDF–13M
19.
Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy
Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui
Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y
PMCID:
PMC9440653
AbstractArticlePDF–2.9M
20.
Functional Proteomics Establishes the Interaction of SIRT7 with Chromatin Remodeling Complexes and Expands Its Role in Regulation of RNA Polymerase I Transcription
Yuan-Chin Tsai, Todd M. Greco, Apaporn Boonmee, Yana Miteva, Ileana M. Cristea
Mol Cell Proteomics. 2012 May; 11(5): 60–76. Published online 2011 Dec 6. doi: 10.1074/mcp.A111.015156
PMCID:
PMC3418843
AbstractArticlePDF–2.5M

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