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Items: 1 to 20 of 116

1.
ASK1-ER stress pathway-mediated fibrotic-EV release contributes to the interaction of alveolar epithelial cells and lung fibroblasts to promote mechanical ventilation-induced pulmonary fibrosis
Ri Tang, Shuya Mei, Qiaoyi Xu, Jinhua Feng, Yang Zhou, Shunpeng Xing, Zhengyu He, Yuan Gao
Exp Mol Med. 2022 Dec; 54(12): 2162–2174. Published online 2022 Dec 6. doi: 10.1038/s12276-022-00901-1
PMCID:
PMC9734805
ArticlePDF–30M
2.
ASK1 is a novel molecular target for preventing aminoglycoside-induced hair cell death
Jacqueline M. Ogier, Yujing Gao, Eileen M. Dunne, Michael A. Wilson, Sarath C. Ranganathan, Gregory H. Tesch, David J. Nikolic Paterson, Alain Dabdoub, Rachel A. Burt, Bryony A. Nayagam, Paul J. Lockhart
J Mol Med (Berl) 2022; 100(5): 797–813. Published online 2022 Apr 26. doi: 10.1007/s00109-022-02188-1
Correction in:
J Mol Med (Berl). 2022; 100(5): 815.
PMCID:
PMC9110505
ArticlePDF–3.6M
3.
ASK1 signaling regulates phase-specific glial interactions during neuroinflammation
Xiaoli Guo, Atsuko Kimura, Kazuhiko Namekata, Chikako Harada, Nobutaka Arai, Kohsuke Takeda, Hidenori Ichijo, Takayuki Harada
Proc Natl Acad Sci U S A. 2022 Feb 8; 119(6): e2103812119. Published online 2022 Jan 31. doi: 10.1073/pnas.2103812119
PMCID:
PMC8832969
ArticlePDF–3.0M
4.
ASK1 suppresses NK cell‐mediated intravascular tumor cell clearance in lung metastasis
Makoto Fujimoto, Miki Kamiyama, Kosuke Fuse, Hiroki Ryuno, Takeru Odawara, Natsuki Furukawa, Yasuhiro Yoshimatsu, Tetsuro Watabe, Michaela Prchal‐Murphy, Veronika Sexl, Hideaki Tahara, Yoshihiro Hayakawa, Takehiro Sato, Kohsuke Takeda, Isao Naguro, Hidenori Ichijo
Cancer Sci. 2021 Apr; 112(4): 1633–1643. Published online 2021 Mar 6. doi: 10.1111/cas.14842
PMCID:
PMC8019214
ArticlePDF–1.2M
5.
ASK1 Regulates Immune-Mediated Thrombocytopenia, Thrombosis, and Systemic Shock
Pravin Patel, Noor F. Shaik, Yuhang Zhou, Kalyan Golla, Steven E. McKenzie, Ulhas P. Naik
J Thromb Haemost. Author manuscript; available in PMC 2021 Nov 1.
Published in final edited form as: J Thromb Haemost. 2020 Nov; 18(11): 3013–3028. Published online 2020 Sep 9. doi: 10.1111/jth.15049
PMCID:
PMC7831975
ArticlePDF–2.9M
6.
Depletion of ASK1 blunts stress-induced senescence in adipocytes
Stephan Wueest, Fabrizio C. Lucchini, Yulia Haim, Assaf Rudich, Daniel Konrad
Adipocyte. 2020; 9(1): 535–541. Published online 2020 Sep 15. doi: 10.1080/21623945.2020.1815977
PMCID:
PMC7714422
ArticlePDF–777K
7.
Apoptosis Signal Regulating Kinase 1 Deletion Mitigates α-Synuclein Pre-formed Fibril Propagation in Mice
Jie Zhang, Eun S. Park, Hye-Jin Park, Run Yan, Magda Grudniewska, Xiaopei Zhang, Stephanie Oh, Xue Yang, Jean Baum, M. Maral Mouradian
Neurobiol Aging. Author manuscript; available in PMC 2021 Jan 1.
Published in final edited form as: Neurobiol Aging. 2020 Jan; 85: 49–57. Published online 2019 Sep 25. doi: 10.1016/j.neurobiolaging.2019.09.012
PMCID:
PMC7064162
ArticlePDF–1.9M
8.
ASK1 promotes uterine inflammation leading to pathological preterm birth
Midori Yoshikawa, Takayuki Iriyama, Kensuke Suzuki, Seisuke Sayama, Tetsushi Tsuruga, Keiichi Kumasawa, Takeshi Nagamatsu, Kengo Homma, Isao Naguro, Yutaka Osuga, Hidenori Ichijo, Tomoyuki Fujii
Sci Rep. 2020; 10: 1887. Published online 2020 Feb 5. doi: 10.1038/s41598-020-58653-9
PMCID:
PMC7002619
ArticlePDF–2.7M
9.
Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis
Hyehun Choi, Ryan J. Stark, Benjamin S. Raja, Anna Dikalova, Fred S. Lamb
Am J Physiol Heart Circ Physiol. 2019 Jun 1; 316(6): H1528–H1537. Published online 2019 Mar 29. doi: 10.1152/ajpheart.00741.2018
PMCID:
PMC6620688
Article
10.
Apoptosis signal-regulating kinase-1 promotes inflammasome priming in macrophages
Camille N. Immanuel, Bin Teng, Brittany Dong, Elizabeth M. Gordon, Joseph A. Kennedy, Charlean Luellen, Andreas Schwingshackl, Stephania A. Cormier, Elizabeth A. Fitzpatrick, Christopher M. Waters
Am J Physiol Lung Cell Mol Physiol. 2019 Mar 1; 316(3): L418–L427. Published online 2019 Jan 10. doi: 10.1152/ajplung.00199.2018
PMCID:
PMC6459294
Article
11.
Inhibition of apoptosis signal-regulating kinase 1 alters the wound epidermis and enhances auricular cartilage regeneration
Qian-Shi Zhang, Deepa S. Kurpad, My G. Mahoney, Marla J. Steinbeck, Theresa A. Freeman
PLoS One. 2017; 12(10): e0185803. Published online 2017 Oct 18. doi: 10.1371/journal.pone.0185803
PMCID:
PMC5646791
ArticlePDF–5.6M
12.
ASK1-dependent endothelial cell activation is critical in ovarian cancer growth and metastasis
Mingzhu Yin, Huanjiao Jenny Zhou, Jiqin Zhang, Caixia Lin, Hongmei Li, Xia Li, Yonghao Li, Haifeng Zhang, David G. Breckenridge, Weidong Ji, Wang Min
JCI Insight. 2017 Sep 21; 2(18): e91828. Published online 2017 Sep 21. doi: 10.1172/jci.insight.91828
PMCID:
PMC5621912
ArticlePDF–8.1M
13.
trans-Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway
Yusuke Hirata, Miki Takahashi, Yuki Kudoh, Kuniyuki Kano, Hiroki Kawana, Kumiko Makide, Yasuharu Shinoda, Yasushi Yabuki, Kohji Fukunaga, Junken Aoki, Takuya Noguchi, Atsushi Matsuzawa
J Biol Chem. 2017 May 19; 292(20): 8174–8185. Published online 2017 Mar 29. doi: 10.1074/jbc.M116.771519
PMCID:
PMC5437226
ArticlePDF–1.8M
14.
ASK1 is involved in cognitive impairment caused by long-term high-fat diet feeding in mice
Kensuke Toyama, Nobutaka Koibuchi, Yu Hasegawa, Ken Uekawa, Osamu Yasuda, Daisuke Sueta, Takashi Nakagawa, Mingjie Ma, Hiroaki Kusaka, Bowen Lin, Hisao Ogawa, Hidenori Ichijo, Shokei Kim-Mitsuyama
Sci Rep. 2015; 5: 10844. Published online 2015 Jun 5. doi: 10.1038/srep10844
Correction in:
Sci Rep. 2015; 5: 14028.
PMCID:
PMC5377457
ArticlePDF–1.5M
15.
Deletion of ASK1 Protects against Hyperoxia-Induced Acute Lung Injury
Jutaro Fukumoto, Ruan Cox, Jr., Itsuko Fukumoto, Young Cho, Prasanna Tamarapu Parthasarathy, Lakshmi Galam, Richard F. Lockey, Narasaiah Kolliputi
PLoS One. 2016; 11(1): e0147652. Published online 2016 Jan 25. doi: 10.1371/journal.pone.0147652
PMCID:
PMC4726536
ArticlePDF–5.6M
16.
Ask1 Gene Deletion Blocks Maternal Diabetes–Induced Endoplasmic Reticulum Stress in the Developing Embryo by Disrupting the Unfolded Protein Response Signalosome
Fang Wang, Yanqing Wu, Hui Gu, E. Albert Reece, Shengyun Fang, Rinat Gabbay-Benziv, Graham Aberdeen, Peixin Yang
Diabetes. 2015 Mar; 64(3): 973–988. Published online 2014 Sep 23. doi: 10.2337/db14-0409
PMCID:
PMC4338585
ArticlePDF–2.9M
17.
Apoptosis Signal Regulating Kinase 1 Modulates the Phenotype of α-Synuclein Transgenic Mice
Kang-Woo Lee, Jong-Min Woo, Joo-Young Im, Eun S. Park, Liqiang He, Hidenori Ichijo, Eunsung Junn, M. Maral Mouradian
Neurobiol Aging. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Neurobiol Aging. 2015 Jan; 36(1): 519–526. Published online 2014 Jul 31. doi: 10.1016/j.neurobiolaging.2014.07.034
PMCID:
PMC4268347
ArticlePDF–2.4M
18.
Inhibition of apoptosis signal-regulating kinase 1 enhances endochondral bone formation by increasing chondrocyte survival
G J Eaton, Q-S Zhang, C Diallo, A Matsuzawa, H Ichijo, M J Steinbeck, T A Freeman
Cell Death Dis. 2014 Nov; 5(11): e1522. Published online 2014 Nov 13. doi: 10.1038/cddis.2014.480
PMCID:
PMC4260738
ArticlePDF–4.8M
19.
Deletion of Apoptosis Signal-Regulating Kinase 1 (ASK1) Protects Pancreatic Beta-Cells from Stress-Induced Death but Not from Glucose Homeostasis Alterations under Pro-Inflammatory Conditions
Emilie Pepin, Arisa Higa, Carole Schuster-Klein, Catherine Bernard, Thierry Sulpice, Beatrice Guardiola, Eric Chevet, Thierry Alquier
PLoS One. 2014; 9(11): e112714. Published online 2014 Nov 10. doi: 10.1371/journal.pone.0112714
PMCID:
PMC4226582
ArticlePDF–876K
20.
Targeting Apoptosis Signalling Kinase-1 (ASK-1) Does Not Prevent the Development of Neuropathy in Streptozotocin-Induced Diabetic Mice
Victoria L. Newton, Sumia Ali, Graham Duddy, Alan J. Whitmarsh, Natalie J. Gardiner
PLoS One. 2014; 9(10): e107437. Published online 2014 Oct 16. doi: 10.1371/journal.pone.0107437
PMCID:
PMC4199525
ArticlePDF–4.2M

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