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Items: 13

Select item 43106471.

GIV/Girdin Links Vascular Endothelial Growth Factor Signaling to Akt Survival Signaling in Podocytes Independent of Nephrin

Honghui Wang, Taro Misaki, Vanessa Taupin, Akiko Eguchi, Pradipta Ghosh, Marilyn G. Farquhar

J Am Soc Nephrol. 2015 Feb; 26(2): 314–327. Published online 2014 Jul 10. doi: 10.1681/ASN.2013090985

PMCID:: PMC4310647

Article

Select item 12914072.

The crucial role of particle surface reactivity in respirable quartz-induced reactive oxygen/nitrogen species formation and APE/Ref-1 induction in rat lung

Catrin Albrecht, Ad M Knaapen, Andrea Becker, Doris Höhr, Petra Haberzettl, Frederik J van Schooten, Paul JA Borm, Roel PF Schins

Respir Res. 2005; 6(1): 129. Published online 2005 Nov 2. doi: 10.1186/1465-9921-6-129

PMCID:: PMC1291407

Article PDF–1.1M

Select item 42261363.

Tyrosine Phosphorylation of the Guanine Nucleotide Exchange Factor GIV Promotes Activation of PI3K During Cell Migration

Changsheng Lin, Jason Ear, Yelena Pavlova, Yash Mittal, Irina Kufareva, Majid Ghassemian, Ruben Abagyan, Mikel Garcia-Marcos, Pradipta Ghosh

Sci Signal. Author manuscript; available in PMC 2014 Nov 10.

Published in final edited form as: Sci Signal. 2011 Sep 27; 4(192): ra64. doi: 10.1126/scisignal.2002049

PMCID:: PMC4226136

Article PDF–3.0M

Select item 28570694.

A Structural Determinant That Renders Gα_i Sensitive to Activation by GIV/Girdin Is Required to Promote Cell Migration

Mikel Garcia-Marcos, Pradipta Ghosh, Jason Ear, Marilyn G. Farquhar

J Biol Chem. 2010 Apr 23; 285(17): 12765–12777. Published online 2010 Feb 15. doi: 10.1074/jbc.M109.045161

PMCID:: PMC2857069

Article PDF–5.4M

Select item 26512825.

GIV is a nonreceptor GEF for Gαi with a unique motif that regulates Akt signaling

Mikel Garcia-Marcos, Pradipta Ghosh, Marilyn G. Farquhar

Proc Natl Acad Sci U S A. 2009 Mar 3; 106(9): 3178–3183. Published online 2009 Feb 11. doi: 10.1073/pnas.0900294106

PMCID:: PMC2651282

Article PDF–919K

Select item 52071406.

Membrane Recruitment of the Non-receptor Protein GIV/Girdin (Gα-interacting, Vesicle-associated Protein/Girdin) Is Sufficient for Activating Heterotrimeric G Protein Signaling

Kshitij Parag-Sharma, Anthony Leyme, Vincent DiGiacomo, Arthur Marivin, Stefan Broselid, Mikel Garcia-Marcos

J Biol Chem. 2016 Dec 30; 291(53): 27098–27111. Published online 2016 Nov 18. doi: 10.1074/jbc.M116.764431

PMCID:: PMC5207140

Article PDF–2.3M

Select item 36192947.

Protein kinase C-theta (PKCθ) phosphorylates and inhibits the guanine exchange factor, GIV/Girdin

Inmaculada López-Sánchez, Mikel Garcia-Marcos, Yash Mittal, Nicolas Aznar, Marilyn G. Farquhar, Pradipta Ghosh

Proc Natl Acad Sci U S A. 2013 Apr 2; 110(14): 5510–5515. Published online 2013 Mar 18. doi: 10.1073/pnas.1303392110

PMCID:: PMC3619294

Article PDF–864K

Select item 28939968.

A Gαi–GIV Molecular Complex Binds Epidermal Growth Factor Receptor and Determines Whether Cells Migrate or Proliferate

Pradipta Ghosh, Anthony O. Beas, Scott J. Bornheimer, Mikel Garcia-Marcos, Erin P. Forry, Carola Johannson, Jason Ear, Barbara H. Jung, Betty Cabrera, John M. Carethers, Marilyn G. Farquhar

Mol Biol Cell. 2010 Jul 1; 21(13): 2338–2354. doi: 10.1091/mbc.E10-01-0028

PMCID:: PMC2893996

Article PDF–4.5M

Select item 50471949.

GIV/Girdin activates Gαi and inhibits Gαs via the same motif

Vijay Gupta, Deepali Bhandari, Anthony Leyme, Nicolas Aznar, Krishna K. Midde, I-Chung Lo, Jason Ear, Ingrid Niesman, Inmaculada López-Sánchez, Juan Bautista Blanco-Canosa, Mark von Zastrow, Mikel Garcia-Marcos, Marilyn G. Farquhar, Pradipta Ghosh

Proc Natl Acad Sci U S A. 2016 Sep 27; 113(39): E5721–E5730. Published online 2016 Sep 12. doi: 10.1073/pnas.1609502113