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Select item 95608391.

SOX8 Knockdown Overcomes Enzalutamide Resistance in Castration-Resistant Prostate Cancer by Inhibiting the Notch Signaling Pathway

Zhongbo Du, Xiaobin Chen, Pingyu Zhu, Wei Sun, Qi Lv, Shulin Cheng, Xuesong Yang, Xiaodong Yu

Biomed Res Int. 2022; 2022: 9235837. Published online 2022 Oct 6. doi: 10.1155/2022/9235837

PMCID:: PMC9560839

Abstract Article PDF–4.6M

Select item 77227912.

The oncogenic role of SOX8 in endometrial carcinoma

Wenyan Tian, Zhanghuan Li, Lu Bai, Lingli Chen, Ye Yan, Huihui Li, Yanyan Han, Fei Teng, Chao Gao, Fengxia Xue, Yingmei Wang

Cancer Biol Ther. 2020; 21(12): 1136–1144. Published online 2020 Nov 16. doi: 10.1080/15384047.2020.1840318

PMCID:: PMC7722791

Abstract Article PDF–7.5M

Select item 73004153.

High SOX8 expression promotes tumor growth and predicts poor prognosis through GOLPH3 signaling in tongue squamous cell carcinoma

Shuwei Chen, Huan Li, Xiyuan Li, Wenkuan Chen, Xing Zhang, Zhongyuan Yang, Zhipeng Chen, Jingtao Chen, Ying Zhang, Dingbo Shi, Ming Song

Cancer Med. 2020 Jun; 9(12): 4274–4289. Published online 2020 Apr 19. doi: 10.1002/cam4.3041

PMCID:: PMC7300415

Abstract Article PDF–2.3M

Select item 66351744.

Over-expression of SOX8 predicts poor prognosis in colorectal cancer: A retrospective study

Yang Wang, Wangshuo Yang, Tianyi Liu, Guang Bai, Mingxing Liu, Wei Wang

Medicine (Baltimore) 2019 Jul; 98(27): e16237. Published online 2019 Jul 5. doi: 10.1097/MD.0000000000016237

PMCID:: PMC6635174

Abstract Article PDF–950K

Select item 61595385.

Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies

Marie-France Portnoi, Marie-Charlotte Dumargne, Sandra Rojo, Selma F Witchel, Andrew J Duncan, Caroline Eozenou, Joelle Bignon-Topalovic, Svetlana A Yatsenko, Aleksandar Rajkovic, Miguel Reyes-Mugica, Kristian Almstrup, Leila Fusee, Yogesh Srivastava, Sandra Chantot-Bastaraud, Capucine Hyon, Christine Louis-Sylvestre, Pierre Validire, Caroline de Malleray Pichard, Celia Ravel, Sophie Christin-Maitre, Raja Brauner, Raffaella Rossetti, Luca Persani, Eduardo H Charreau, Liliana Dain, Violeta A Chiauzzi, Inas Mazen, Hassan Rouba, Caroline Schluth-Bolard, Stuart MacGowan, W H Irwin McLean, Etienne Patin, Ewa Rajpert-De Meyts, Ralf Jauch, John C Achermann, Jean-Pierre Siffroi, Ken McElreavey, Anu Bashamboo

Hum Mol Genet. 2018 Apr 1; 27(7): 1228–1240. Published online 2018 Jan 24. doi: 10.1093/hmg/ddy037

PMCID:: PMC6159538

Abstract Article PDF–1.9M

Select item 99904516.

Additional evidence for the role of chromosomal imbalances and SOX8, ZNRF3 and HHAT gene variants in early human testis development

Khouloud Rjiba, Soumaya Mougou-Zerelli, Imen hadj Hamida, Ghada Saad, Bochra Khadija, Afef Jelloul, Wafa Slimani, Yosra Hasni, Sarra Dimassi, Hela Ben khelifa, Amira Sallem, Molka Kammoun, Hamza Hadj Abdallah, Moez Gribaa, Joelle Bignon-Topalovic, Sami Chelly, Hédi Khairi, Mohamed Bibi, Maha Kacem, Ali Saad, Anu Bashamboo, Kenneth McElreavey

Reprod Biol Endocrinol. 2023; 21: 2. Published online 2023 Jan 11. doi: 10.1186/s12958-022-01045-7

PMCID:: PMC9990451

Abstract Article PDF–1.2M

Select item 72950657.

Aurora-A/SOX8/FOXK1 signaling axis promotes chemoresistance via suppression of cell senescence and induction of glucose metabolism in ovarian cancer organoids and cells

Huizhen Sun, Husheng Wang, Xue Wang, Yoichi Aoki, Xinjing Wang, Yufei Yang, Xi Cheng, Ziliang Wang, Xipeng Wang

Theranostics. 2020; 10(15): 6928–6945. Published online 2020 May 25. doi: 10.7150/thno.43811

PMCID:: PMC7295065

Abstract Article PDF–3.9M

Select item 64468678.

Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice

Shunsuke Kimura, Nobuhide Kobayashi, Yutaka Nakamura, Takashi Kanaya, Daisuke Takahashi, Ryoji Fujiki, Mami Mutoh, Yuuki Obata, Toshihiko Iwanaga, Tomoo Nakagawa, Naoya Kato, Shintaro Sato, Tsuneyasu Kaisho, Hiroshi Ohno, Koji Hase

J Exp Med. 2019 Apr 1; 216(4): 831–846. Published online 2019 Mar 15. doi: 10.1084/jem.20181604

PMCID:: PMC6446867

Abstract Article PDF–4.3M

Select item 66498429.

The SOXE transcription factors—SOX8, SOX9 and SOX10—share a bi-partite transactivation mechanism

Abdul Haseeb, Véronique Lefebvre

Nucleic Acids Res. 2019 Jul 26; 47(13): 6917–6931. Published online 2019 Jun 13. doi: 10.1093/nar/gkz523

PMCID:: PMC6649842

Abstract Article PDF–5.5M

Select item 423011010.

miRNA-124 down-regulates SOX8 expression and suppresses cell proliferation in non-small cell lung cancer

Chao Xie, Yunwei Han, Yi Liu, Lei Han, Jie Liu

Int J Clin Exp Pathol. 2014; 7(10): 6534–6542. Published online 2014 Sep 15.

PMCID:: PMC4230110

Abstract Article PDF–1.1M

Select item 367346311.

MANBA, CXCR5, SOX8, RPS6KB1 and ZBTB46 are genetic risk loci for multiple sclerosis

International Multiple Sclerosis Genetics Consortium, Christina M. Lill, Brit-Maren M. Schjeide, Christiane Graetz, Maria Ban, Antonio Alcina, Miguel A. Ortiz, Jennifer Pérez, Vincent Damotte, David Booth, Aitzkoa Lopez de Lapuente, Linda Broer, Marcel Schilling, Denis A. Akkad, Orhan Aktas, Iraide Alloza, Alfredo Antigüedad, Rafa Arroyo, Paul Blaschke, Mathias Buttmann, Andrew Chan, Alastair Compston, Isabelle Cournu-Rebeix, Thomas Dörner, Joerg T. Epplen, Óscar Fernández, Lisa-Ann Gerdes, Léna Guillot-Noël, Hans-Peter Hartung, Sabine Hoffjan, Guillermo Izquierdo, Anu Kemppinen, Antje Kroner, Christian Kubisch, Tania Kümpfel, Shu-Chen Li, Ulman Lindenberger, Peter Lohse, Catherine Lubetzki, Felix Luessi, Sunny Malhotra, Julia Mescheriakova, Xavier Montalban, Caroline Papeix, Lidia F. Paredes, Peter Rieckmann, Elisabeth Steinhagen-Thiessen, Alexander Winkelmann, Uwe K. Zettl, Rogier Hintzen, Koen Vandenbroeck, Graeme Stewart, Bertrand Fontaine, Manuel Comabella, Elena Urcelay, Fuencisla Matesanz, Stephen Sawcer, Lars Bertram, Frauke Zipp

Brain. 2013 Jun; 136(6): 1778–1782. Published online 2013 Jun 4. doi: 10.1093/brain/awt101

PMCID:: PMC3673463

Abstract Article PDF–227K

Select item 11103712.

Cloning and characterisation of the Sry-related transcription factor gene Sox8

Goslik E. Schepers, Monica Bullejos, Brett M. Hosking, Peter Koopman

Nucleic Acids Res. 2000 Mar 15; 28(6): 1473–1480. doi: 10.1093/nar/28.6.1473

PMCID:: PMC111037

Abstract Article PDF–813K

Select item 142150413.

The high-mobility-group domain of Sox proteins interacts with DNA-binding domains of many transcription factors

Sandra Wißmüller, Thomas Kosian, Michael Wolf, Markus Finzsch, Michael Wegner

Nucleic Acids Res. 2006; 34(6): 1735–1744. Published online 2006 Mar 31. doi: 10.1093/nar/gkl105

PMCID:: PMC1421504

Abstract Article PDF–647K

Select item 318253114.

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

The International Multiple Sclerosis Genetics Consortium (IMSGC), Wellcome Trust Case Control Consortium 2 (WTCCC2), Stephen Sawcer, Garrett Hellenthal, Matti Pirinen, Chris C.A. Spencer, Nikolaos A. Patsopoulos, Loukas Moutsianas, Alexander Dilthey, Zhan Su, Colin Freeman, Sarah E. Hunt, Sarah Edkins, Emma Gray, David R. Booth, Simon C. Potter, An Goris, Gavin Band, Annette Bang Oturai, Amy Strange, Janna Saarela, Céline Bellenguez, Bertrand Fontaine, Matthew Gillman, Bernhard Hemmer, Rhian Gwilliam, Frauke Zipp, Alagurevathi Jayakumar, Roland Martin, Stephen Leslie, Stanley Hawkins, Eleni Giannoulatou, Sandra D’alfonso, Hannah Blackburn, Filippo Martinelli Boneschi, Jennifer Liddle, Hanne F. Harbo, Marc L. Perez, Anne Spurkland, Matthew J Waller, Marcin P. Mycko, Michelle Ricketts, Manuel Comabella, Naomi Hammond, Ingrid Kockum, Owen T. McCann, Maria Ban, Pamela Whittaker, Anu Kemppinen, Paul Weston, Clive Hawkins, Sara Widaa, John Zajicek, Serge Dronov, Neil Robertson, Suzannah J. Bumpstead, Lisa F. Barcellos, Rathi Ravindrarajah, Roby Abraham, Lars Alfredsson, Kristin Ardlie, Cristin Aubin, Amie Baker, Katharine Baker, Sergio E. Baranzini, Laura Bergamaschi, Roberto Bergamaschi, Allan Bernstein, Achim Berthele, Mike Boggild, Jonathan P. Bradfield, David Brassat, Simon A. Broadley, Dorothea Buck, Helmut Butzkueven, Ruggero Capra, William M. Carroll, Paola Cavalla, Elisabeth G. Celius, Sabine Cepok, Rosetta Chiavacci, Françoise Clerget-Darpoux, Katleen Clysters, Giancarlo Comi, Mark Cossburn, Isabelle Cournu-Rebeix, Mathew B. Cox, Wendy Cozen, Bruce A.C. Cree, Anne H. Cross, Daniele Cusi, Mark J. Daly, Emma Davis, Paul I.W. de Bakker, Marc Debouverie, Marie Beatrice D’hooghe, Katherine Dixon, Rita Dobosi, Bénédicte Dubois, David Ellinghaus, Irina Elovaara, Federica Esposito, Claire Fontenille, Simon Foote, Andre Franke, Daniela Galimberti, Angelo Ghezzi, Joseph Glessner, Refujia Gomez, Olivier Gout, Colin Graham, Struan F.A. Grant, Franca Rosa Guerini, Hakon Hakonarson, Per Hall, Anders Hamsten, Hans-Peter Hartung, Rob N. Heard, Simon Heath, Jeremy Hobart, Muna Hoshi, Carmen Infante-Duarte, Gillian Ingram, Wendy Ingram, Talat Islam, Maja Jagodic, Michael Kabesch, Allan G. Kermode, Trevor J. Kilpatrick, Cecilia Kim, Norman Klopp, Keijo Koivisto, Malin Larsson, Mark Lathrop, Jeannette S. Lechner-Scott, Maurizio A. Leone, Virpi Leppä, Ulrika Liljedahl, Izaura Lima Bomfim, Robin R. Lincoln, Jenny Link, Jianjun Liu, Åslaug R. Lorentzen, Sara Lupoli, Fabio Macciardi, Thomas Mack, Mark Marriott, Vittorio Martinelli, Deborah Mason, Jacob L. McCauley, Frank Mentch, Inger-Lise Mero, Tania Mihalova, Xavier Montalban, John Mottershead, Kjell-Morten Myhr, Paola Naldi, William Ollier, Alison Page, Aarno Palotie, Jean Pelletier, Laura Piccio, Trevor Pickersgill, Fredrik Piehl, Susan Pobywajlo, Hong L. Quach, Patricia P. Ramsay, Mauri Reunanen, Richard Reynolds, John D. Rioux, Mariaemma Rodegher, Sabine Roesner, Justin P. Rubio, Ina-Maria Rückert, Marco Salvetti, Erika Salvi, Adam Santaniello, Catherine A. Schaefer, Stefan Schreiber, Christian Schulze, Rodney J. Scott, Finn Sellebjerg, Krzysztof W. Selmaj, David Sexton, Ling Shen, Brigid Simms-Acuna, Sheila Skidmore, Patrick M.A. Sleiman, Cathrine Smestad, Per Soelberg Sørensen, Helle Bach Søndergaard, Jim Stankovich, Richard C. Strange, Anna-Maija Sulonen, Emilie Sundqvist, Ann-Christine Syvänen, Francesca Taddeo, Bruce Taylor, Jenefer M. Blackwell, Pentti Tienari, Elvira Bramon, Ayman Tourbah, Matthew A. Brown, Ewa Tronczynska, Juan P. Casas, Niall Tubridy, Aiden Corvin, Jane Vickery, Janusz Jankowski, Pablo Villoslada, Hugh S. Markus, Kai Wang, Christopher G. Mathew, James Wason, Colin N.A. Palmer, H-Erich Wichmann, Robert Plomin, Ernest Willoughby, Anna Rautanen, Juliane Winkelmann, Michael Wittig, Richard C. Trembath, Jacqueline Yaouanq, Ananth C. Viswanathan, Haitao Zhang, Nicholas W. Wood, Rebecca Zuvich, Panos Deloukas, Cordelia Langford, Audrey Duncanson, Jorge R. Oksenberg, Margaret A. Pericak-Vance, Jonathan L. Haines, Tomas Olsson, Jan Hillert, Adrian J. Ivinson, Philip L. De Jager, Leena Peltonen, Graeme J. Stewart, David A. Hafler, Stephen L. Hauser, Gil McVean, Peter Donnelly, Alastair Compston

Nature. Author manuscript; available in PMC 2012 Feb 11.

Published in final edited form as: Nature. 2011 Aug 10; 476(7359): 214–219. Published online 2011 Aug 10. doi: 10.1038/nature10251

PMCID:: PMC3182531

Abstract Article PDF–2.0M

Select item 876331715.

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1–CoREST interactome during embryonic stem cell differentiation

Claire E. Barnes, David M. English, Megan Broderick, Mark O. Collins, Shaun M. Cowley

Mol Omics. 2022 Jan 17; 18(1): 31–44. Published online 2021 Oct 14. doi: 10.1039/d1mo00236h

PMCID:: PMC8763317

Abstract Article

Select item 800904816.

Impact of cytosine methylation on DNA binding specificities of human transcription factors

Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale

Science. Author manuscript; available in PMC 2021 Mar 30.

Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239

PMCID:: PMC8009048

Abstract Article PDF–2.6M

Select item 283626717.

An atlas of combinatorial transcriptional regulation in mouse and man

The FANTOM consortium and RIKEN Omics Science Center

Cell. Author manuscript; available in PMC 2011 Mar 5.

Published in final edited form as: Cell. 2010 Mar 5; 140(5): 744–752. doi: 10.1016/j.cell.2010.01.044

Correction in:: volume 141 on page 369

PMCID:: PMC2836267

Abstract Article PDF–2.2M

Select item 326170818.

Toward an understanding of the protein interaction network of the human liver

Jian Wang, Keke Huo, Lixin Ma, Liujun Tang, Dong Li, Xiaobi Huang, Yanzhi Yuan, Chunhua Li, Wei Wang, Wei Guan, Hui Chen, Chaozhi Jin, Junchen Wei, Wanqiao Zhang, Yongsheng Yang, Qiongming Liu, Ying Zhou, Cuili Zhang, Zhihao Wu, Wangxiang Xu, Ying Zhang, Tao Liu, Donghui Yu, Yaping Zhang, Liang Chen, Dewu Zhu, Xing Zhong, Lixin Kang, Xiang Gan, Xiaolan Yu, Qi Ma, Jing Yan, Li Zhou, Zhongyang Liu, Yunping Zhu, Tao Zhou, Fuchu He, Xiaoming Yang

Mol Syst Biol. 2011; 7: 536. Published online 2011 Oct 11. doi: 10.1038/msb.2011.67