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Select item 104321751.

HNRNPC haploinsufficiency affects alternative splicing of intellectual disability-associated genes and causes a neurodevelopmental disorder

Eva Niggl, Arjan Bouman, Lauren C. Briere, Remco M. Hoogenboezem, Ilse Wallaard, Joohyun Park, Jakob Admard, Martina Wilke, Emilio D.R.O. Harris-Mostert, Minetta Elgersma, Jennifer Bain, Meena Balasubramanian, Siddharth Banka, Paul J. Benke, Miriam Bertrand, Alyssa E. Blesson, Jill Clayton-Smith, Jamie M. Ellingford, Madelyn A. Gillentine, Dana H. Goodloe, Tobias B. Haack, Mahim Jain, Ian Krantz, Sharon M. Luu, Molly McPheron, Candace L. Muss, Sarah E. Raible, Nathaniel H. Robin, Michael Spiller, Susan Starling, David A. Sweetser, Isabelle Thiffault, Francesco Vetrini, Dennis Witt, Emily Woods, Dihong Zhou, Genomics England Research Consortium, Undiagnosed Diseases Network, Ype Elgersma, Annelot C.M. van Esbroeck

Am J Hum Genet. 2023 Aug 3; 110(8): 1414–1435. Published online 2023 Aug 3. doi: 10.1016/j.ajhg.2023.07.005

PMCID:: PMC10432175

Abstract Article PDF–4.8M

Select item 102972972.

HnRNP Pathologies in Frontotemporal Lobar Degeneration

Xinwa Jiang, Ariana Gatt, Tammaryn Lashley

Cells. 2023 Jun; 12(12): 1633. Published online 2023 Jun 15. doi: 10.3390/cells12121633

PMCID:: PMC10297297

Abstract Article PDF–873K

Select item 101548013.

HNRNPC suppresses tumor immune microenvironment by activating Treg cells promoting the progression of prostate cancer

Yifei Cheng, Lu Li, Xiyi Wei, Fan Xu, Xiaochen Huang, Feng Qi, Yanyan Zhang, Xiao Li

Cancer Sci. 2023 May; 114(5): 1830–1845. Published online 2023 Feb 13. doi: 10.1111/cas.15745

PMCID:: PMC10154801

Abstract Article PDF–14M

Select item 97619594.

HNRNPC, a predictor of prognosis and immunotherapy response based on bioinformatics analysis, is related to proliferation and invasion of NSCLC cells

Zhuoyu Gu, Yang Yang, Qian Ma, Hui Wang, Song Zhao, Yu Qi, Yixin Li

Respir Res. 2022; 23: 362. Published online 2022 Dec 19. doi: 10.1186/s12931-022-02227-y

PMCID:: PMC9761959

Abstract Article PDF–6.7M

Select item 95308785.

HNRNPC downregulation inhibits IL‐6/STAT3‐mediated HCC metastasis by decreasing HIF1A expression

Danfei Liu, Xiangyuan Luo, Meng Xie, Tongyue Zhang, Xiaoping Chen, Bixiang Zhang, Mengyu Sun, Yijun Wang, Yangyang Feng, Xiaoyu Ji, Yiwei Li, Bifeng Liu, Wenjie Huang, Limin Xia

Cancer Sci. 2022 Oct; 113(10): 3347–3361. Published online 2022 Aug 12. doi: 10.1111/cas.15494

PMCID:: PMC9530878

Abstract Article PDF–52M

Select item 90045566.

A systematic pan-cancer study demonstrates the oncogenic function of heterogeneous nuclear ribonucleoprotein C

Chenxi Pan, Qian Wu, Nianjie Feng

Aging (Albany NY) 2022 Mar 31; 14(6): 2880–2901. Published online 2022 Mar 28. doi: 10.18632/aging.203981

PMCID:: PMC9004556

Abstract Article PDF–4.6M

Select item 89954387.

HNRNPC regulates RhoA to induce DNA damage repair and cancer‐associated fibroblast activation causing radiation resistance in pancreatic cancer

Ning Xia, Nannan Yang, Qungang Shan, Ziyin Wang, Xiaoyu Liu, Yingjie Chen, Jian Lu, Wei Huang, Zhongmin Wang

J Cell Mol Med. 2022 Apr; 26(8): 2322–2336. Published online 2022 Mar 11. doi: 10.1111/jcmm.17254

PMCID:: PMC8995438

Abstract Article PDF–2.7M

Select item 73434698.

Guang-Zhao Huang, Qing-Qing Wu, Ze-Nan Zheng, Ting-Ru Shao, Yue-Chuan Chen, Wei-Sen Zeng, Xiao-Zhi Lv

Aging (Albany NY) 2020 Jun 30; 12(12): 11667–11684. Published online 2020 Jun 11. doi: 10.18632/aging.103333

PMCID:: PMC7343469

Abstract Article PDF–2.3M

Select item 66986469.

hnRNPC regulates cancer-specific alternative cleavage and polyadenylation profiles

Harry Fischl, Jonathan Neve, Zhiqiao Wang, Radhika Patel, Alastair Louey, Bin Tian, Andre Furger

Nucleic Acids Res. 2019 Aug 22; 47(14): 7580–7591. Published online 2019 May 31. doi: 10.1093/nar/gkz461

PMCID:: PMC6698646

Abstract Article PDF–3.5M

Select item 669353510.

Strand-specific affinity of host factor hnRNP C1/C2 guides positive to negative-strand ratio in Coxsackievirus B3 infection

Pratik Dave, Biju George, Sreenath Balakrishnan, Divya Khandige Sharma, Harsha Raheja, Narendra M. Dixit, Saumitra Das

RNA Biol. 2019 Sep; 16(9): 1286–1299. Published online 2019 Jun 24. doi: 10.1080/15476286.2019.1629208

PMCID:: PMC6693535

Abstract Article PDF–4.5M

Select item 627688011.

Function of HNRNPC in breast cancer cells by controlling the dsRNA‐induced interferon response

Yusheng Wu, Wenwei Zhao, Yang Liu, Xiangtian Tan, Xin Li, Qin Zou, Zhengtao Xiao, Hui Xu, Yuting Wang, Xuerui Yang

EMBO J. 2018 Dec 3; 37(23): e99017. Published online 2018 Aug 29. doi: 10.15252/embj.201899017

PMCID:: PMC6276880

Abstract Article PDF–3.0M

Select item 531479112.

Concerted effects of heterogeneous nuclear ribonucleoprotein C1/C2 to control vitamin D-directed gene transcription and RNA splicing in human bone cells

Rui Zhou, Juw Won Park, Rene F. Chun, Thomas S. Lisse, Alejandro J. Garcia, Kathryn Zavala, Jessica L. Sea, Zhi-xiang Lu, Jianzhong Xu, John S. Adams, Yi Xing, Martin Hewison

Nucleic Acids Res. 2017 Jan 25; 45(2): 606–618. Published online 2016 Sep 26. doi: 10.1093/nar/gkw851

PMCID:: PMC5314791

Abstract Article PDF–4.8M

Select item 450558513.

Heterogeneous Nuclear Ribonucleoprotein C Proteins Interact with the Human Papillomavirus Type 16 (HPV16) Early 3′-Untranslated Region and Alleviate Suppression of HPV16 Late L1 mRNA Splicing

Soniya Dhanjal, Naoko Kajitani, Jacob Glahder, Ann-Kristin Mossberg, Cecilia Johansson, Stefan Schwartz

J Biol Chem. 2015 May 22; 290(21): 13354–13371. Published online 2015 Apr 15. doi: 10.1074/jbc.M115.638098

PMCID:: PMC4505585

Abstract Article PDF–1.1M

Select item 435167614.

Role of human heterogeneous nuclear ribonucleoprotein C1/C2 in dengue virus replication

Thanyaporn Dechtawewat, Pucharee Songprakhon, Thawornchai Limjindaporn, Chunya Puttikhunt, Watchara Kasinrerk, Sawanan Saitornuang, Pa-thai Yenchitsomanus, Sansanee Noisakran

Virol J. 2015; 12: 14. Published online 2015 Feb 6. doi: 10.1186/s12985-014-0219-7