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Select item 68303171.

Lack of a Retinal Phenotype in a Syne-2/Nesprin-2 Knockout Mouse Model

Nathalie Falk, Anneka Joachimsthaler, Kristin Kessler, Uwe Thorsten Lux, Angelika Anna Noegel, Jan Kremers, Johann Helmut Brandstätter, Andreas Gießl

Cells. 2019 Oct; 8(10): 1238. Published online 2019 Oct 11. doi: 10.3390/cells8101238

PMCID:: PMC6830317

Abstract Article PDF–5.1M

Select item 62447302.

Depletion of Nesprin-2 is associated with an embryonic lethal phenotype in mice

Carmen Mroß, Marija Marko, Martina Munck, Gernot Glöckner, Susanne Motameny, Janine Altmüller, Angelika A. Noegel, Ludwig Eichinger, Vivek S. Peche, Sascha Neumann

Nucleus. 2018; 9(1): 503–515. Published online 2018 Sep 17. doi: 10.1080/19491034.2018.1523664

PMCID:: PMC6244730

Abstract Article PDF–2.1M

Select item 48058613.

Nesprin-2G, a Component of the Nuclear LINC Complex, Is Subject to Myosin-Dependent Tension

Paul T. Arsenovic, Iswarya Ramachandran, Kranthidhar Bathula, Ruijun Zhu, Jiten D. Narang, Natalie A. Noll, Christopher A. Lemmon, Gregg G. Gundersen, Daniel E. Conway

Biophys J. 2016 Jan 5; 110(1): 34–43. Published online 2016 Jan 5. doi: 10.1016/j.bpj.2015.11.014

PMCID:: PMC4805861

Abstract Article PDF–1.2M

Select item 33835734.

The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing

R.N. Rashmi, Beate Eckes, Gernot Glöckner, Marco Groth, Sascha Neumann, Joachim Gloy, Lorenz Sellin, Gerd Walz, Maria Schneider, Iakowos Karakesisoglou, Ludwig Eichinger, Angelika A. Noegel

Nucleus. 2012 Mar 1; 3(2): 172–186. doi: 10.4161/nucl.19090

PMCID:: PMC3383573

Abstract Article PDF–5.3M

Select item 76597195.

Nesprins are mechanotransducers that discriminate epithelial–mesenchymal transition programs

Théophile Déjardin, Pietro Salvatore Carollo, François Sipieter, Patricia M. Davidson, Cynthia Seiler, Damien Cuvelier, Bruno Cadot, Cecile Sykes, Edgar R. Gomes, Nicolas Borghi

J Cell Biol. 2020 Oct 5; 219(10): e201908036. Published online 2020 Aug 13. doi: 10.1083/jcb.201908036

PMCID:: PMC7659719

Abstract Article PDF–4.9M

Select item 44684236.

A Mutation in Syne2 Causes Early Retinal Defects in Photoreceptors, Secondary Neurons, and Müller Glia

Dennis M. Maddox, Gayle B. Collin, Akihiro Ikeda, C. Herbert Pratt, Sakae Ikeda, Britt A. Johnson, Ron E. Hurd, Lindsay S. Shopland, Jürgen K. Naggert, Bo Chang, Mark P. Krebs, Patsy M. Nishina

Invest Ophthalmol Vis Sci. 2015 Jun; 56(6): 3776–3787. Published online 2015 Jun 11. doi: 10.1167/iovs.14-16047

PMCID:: PMC4468423

Abstract Article PDF–2.0M

Select item 39304907.

Targeted Ablation of Nesprin 1 and Nesprin 2 from Murine Myocardium Results in Cardiomyopathy, Altered Nuclear Morphology and Inhibition of the Biomechanical Gene Response

Indroneal Banerjee, Jianlin Zhang, Thomas Moore-Morris, Emily Pfeiffer, Kyle S. Buchholz, Ao Liu, Kunfu Ouyang, Matthew J. Stroud, Larry Gerace, Sylvia M. Evans, Andrew McCulloch, Ju Chen

PLoS Genet. 2014 Feb; 10(2): e1004114. Published online 2014 Feb 20. doi: 10.1371/journal.pgen.1004114

PMCID:: PMC3930490

Abstract Article PDF–2.6M

Select item 29661078.

Nesprin-2 Interacts with α-Catenin and Regulates Wnt Signaling at the Nuclear Envelope

Sascha Neumann, Maria Schneider, Rebecca L. Daugherty, Cara J. Gottardi, Sabine A. Eming, Asa Beijer, Angelika A. Noegel, Iakowos Karakesisoglou

J Biol Chem. 2010 Nov 5; 285(45): 34932–34938. Published online 2010 Aug 26. doi: 10.1074/jbc.M110.119651

PMCID:: PMC2966107

Abstract Article PDF–2.6M

Select item 35481909.

The LINC-anchored actin cap connects the extracellular milieu to the nucleus for ultrafast mechanotransduction

Allison B. Chambliss, Shyam B. Khatau, Nicholas Erdenberger, D. Kyle Robinson, Didier Hodzic, Gregory D. Longmore, Denis Wirtz

Sci Rep. 2013; 3: 1087. Published online 2013 Jan 18. doi: 10.1038/srep01087

PMCID:: PMC3548190

Abstract Article PDF–1.8M

Select item 277650210.

Dynamics and molecular interactions of linker of nucleoskeleton and cytoskeleton (LINC) complex proteins

Cecilia Östlund, Eric S. Folker, Jason C. Choi, Edgar R. Gomes, Gregg G. Gundersen, Howard J. Worman

J Cell Sci. 2009 Nov 15; 122(22): 4099–4108. Published online 2009 Oct 20. doi: 10.1242/jcs.057075

PMCID:: PMC2776502

Abstract Article

Select item 346532411.

LINC Complexes Mediate the Positioning of Cone Photoreceptor Nuclei in Mouse Retina

David Razafsky, Nathaniel Blecher, Alexander Markov, P. J. Stewart-Hutchinson, Didier Hodzic

PLoS One. 2012; 7(10): e47180. Published online 2012 Oct 5. doi: 10.1371/journal.pone.0047180

PMCID:: PMC3465324

Abstract Article PDF–9.4M

Select item 148899912.

SUN1 Interacts with Nuclear Lamin A and Cytoplasmic Nesprins To Provide a Physical Connection between the Nuclear Lamina and the Cytoskeleton

Farhana Haque, David J. Lloyd, Dawn T. Smallwood, Carolyn L. Dent, Catherine M. Shanahan, Andrew M. Fry, Richard C. Trembath, Sue Shackleton

Mol Cell Biol. 2006 May; 26(10): 3738–3751. doi: 10.1128/MCB.26.10.3738-3751.2006

PMCID:: PMC1488999

Abstract Article PDF–1.3M

Select item 597430113.

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap

Anna Woroniuk, Andrew Porter, Gavin White, Daniel T. Newman, Zoi Diamantopoulou, Thomas Waring, Claire Rooney, Douglas Strathdee, Daniel J. Marston, Klaus M. Hahn, Owen J. Sansom, Tobias Zech, Angeliki Malliri

Nat Commun. 2018; 9: 2124. Published online 2018 May 29. doi: 10.1038/s41467-018-04404-4