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Items: 1 to 20 of 54

1.
Age-dependent effects of Igf2bp2 on gene regulation, function, and aging of hematopoietic stem cells in mice
Miaomiao Suo, Megan K. Rommelfanger, Yulin Chen, Elias Moris Amro, Bing Han, Zhiyang Chen, Karol Szafranski, Sundaram Reddy Chakkarappan, Bernhard O. Boehm, Adam L. MacLean, K. Lenhard Rudolph
Blood. 2022 Apr 28; 139(17): 2653–2665. Published online 2022 Mar 3. doi: 10.1182/blood.2021012197
PMCID:
PMC11022928
Article
2.
RNA binding protein IGF2BP2 expression is induced by stress in the heart and mediates dilated cardiomyopathy
Miriam Krumbein, Froma Oberman, Yuval Cinnamon, Mordechai Golomb, Dalit May, Gilad Vainer, Vitali Belzer, Karen Meir, Irina Fridman, Johannes Haybaeck, Gerhard Poelzl, Izhak Kehat, Ronen Beeri, Sonja M. Kessler, Joel K. Yisraeli
Commun Biol. 2023; 6: 1229. Published online 2023 Dec 5. doi: 10.1038/s42003-023-05547-x
PMCID:
PMC10698010
ArticlePDF–2.8M
3.
Degradation of NLRP3 by p62‐dependent‐autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia
Dongyuan Zhang, Yu Zhang, Jirong Pan, Jingjing Cao, Xiuping Sun, Xianglei Li, Ling Zhang, Chuan Qin
CNS Neurosci Ther. 2023 Oct; 29(10): 2826–2842. Published online 2023 Apr 18. doi: 10.1111/cns.14219
PMCID:
PMC10493665
ArticlePDF–29M
4.
Neuron-Specific IMP2 Overexpression by Synapsin Promoter-Driven AAV9: A Tool to Study Its Role in Axon Regeneration
Sarah Blizard, Danielle Park, Natalie O’Toole, Sheeva Norooz, Martin Dela Torre, Young Son, Adam Holstein, Scarlett Austin, Joshua Harman, Samantha Haraszti, Daved Fared, Mei Xu
Cells. 2021 Oct; 10(10): 2654. Published online 2021 Oct 5. doi: 10.3390/cells10102654
PMCID:
PMC8534607
ArticlePDF–1.2M
5.
TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation
Xiaochen Fan, V Pragathi Masamsetti, Jane QJ Sun, Kasper Engholm-Keller, Pierre Osteil, Joshua Studdert, Mark E Graham, Nicolas Fossat, Patrick PL Tam
eLife. 2021; 10: e62873. Published online 2021 Feb 8. doi: 10.7554/eLife.62873
PMCID:
PMC7968925
ArticlePDF–4.0M
6.
IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype
S M Kessler, S Laggai, A Barghash, C S Schultheiss, E Lederer, M Artl, V Helms, J Haybaeck, A K Kiemer
Cell Death Dis. 2015 Oct; 6(10): e1894. Published online 2015 Oct 1. doi: 10.1038/cddis.2015.241
PMCID:
PMC4632283
ArticlePDF–4.3M
7.
Elevated free cholesterol in a p62 overexpression model of non-alcoholic steatohepatitis
Yvette Simon, Sonja M Kessler, Katja Gemperlein, Rainer M Bohle, Rolf Müller, Johannes Haybaeck, Alexandra K Kiemer
World J Gastroenterol. 2014 Dec 21; 20(47): 17839–17850. Published online 2014 Dec 21. doi: 10.3748/wjg.v20.i47.17839
PMCID:
PMC4273134
ArticlePDF–1.4M
8.
The IGF2 mRNA binding protein p62/IGF2BP2-2 induces fatty acid elongation as a critical feature of steatosis
Stephan Laggai, Sonja M. Kessler, Stefan Boettcher, Valérie Lebrun, Katja Gemperlein, Eva Lederer, Isabelle A. Leclercq, Rolf Mueller, Rolf W. Hartmann, Johannes Haybaeck, Alexandra K. Kiemer
J Lipid Res. 2014 Jun; 55(6): 1087–1097. doi: 10.1194/jlr.M045500
Correction in:
J Lipid Res. 2016 Jul; 57(7): 1323.
PMCID:
PMC4031940
ArticlePDF–1.7M
9.
Let-7e-5p Regulates IGF2BP2, and Induces Muscle Atrophy
Takuro Okamura, Hiroshi Okada, Yoshitaka Hashimoto, Saori Majima, Takafumi Senmaru, Naoko Nakanishi, Mai Asano, Masahiro Yamazaki, Masahide Hamaguchi, Michiaki Fukui
Front Endocrinol (Lausanne) 2021; 12: 791363. Published online 2021 Dec 24. doi: 10.3389/fendo.2021.791363
PMCID:
PMC8741024
ArticlePDF–17M
10.
The m6A reader IMP2 directs autoimmune inflammation through an IL-17- and TNFα-dependent C/EBP transcription factor axis
Rami Bechara, Nilesh Amatya, Rachel D. Bailey, Yang Li, Felix EY Aggor, De-Dong Li, Chetan V. Jawale, Bianca M. Coleman, Ning Dai, Nandan S. Gokhale, Tiffany C. Taylor, Stacy M. Horner, Amanda C. Poholek, Anita Bansal, Partha S. Biswas, Sarah L. Gaffen
Sci Immunol. Author manuscript; available in PMC 2022 Jan 2.
Published in final edited form as: Sci Immunol. 2021 Jul 2; 6(61): eabd1287. doi: 10.1126/sciimmunol.abd1287
PMCID:
PMC8404281
ArticlePDF–2.5M
11.
Lnc-ORA interacts with microRNA-532-3p and IGF2BP2 to inhibit skeletal muscle myogenesis
Rui Cai, Que Zhang, Yingqian Wang, Wenlong Yong, Rui Zhao, Weijun Pang
J Biol Chem. 2021 Jan-Jun; 296: 100376. Published online 2021 Feb 4. doi: 10.1016/j.jbc.2021.100376
PMCID:
PMC8289116
ArticlePDF–6.3M
12.
The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPARγ
Xia Wang, Yuge Ji, Panpan Feng, Rucheng Liu, Guosheng Li, Junjie Zheng, Yaqiang Xue, Yaxun Wei, Chunyan Ji, Dawei Chen, Jingxin Li
Adv Sci (Weinh) 2021 Jul; 8(13): 2100209. Published online 2021 May 3. doi: 10.1002/advs.202100209
PMCID:
PMC8261491
ArticlePDF–5.3M
13.
RNA m6A reader IMP2/IGF2BP2 promotes pancreatic β-cell proliferation and insulin secretion by enhancing PDX1 expression
Laura Regué, Liping Zhao, Fei Ji, Hua Wang, Joseph Avruch, Ning Dai
Mol Metab. 2021 Jun; 48: 101209. Published online 2021 Mar 9. doi: 10.1016/j.molmet.2021.101209
PMCID:
PMC8076713
ArticlePDF–2.3M
14.
Liver-specific deletion of IGF2 mRNA binding protein-2/IMP2 reduces hepatic fatty acid oxidation and increases hepatic triglyceride accumulation
Laura Regué, Liliana Minichiello, Joseph Avruch, Ning Dai
J Biol Chem. 2019 Aug 2; 294(31): 11944–11951. Published online 2019 Jun 17. doi: 10.1074/jbc.RA119.008778
PMCID:
PMC6682725
ArticlePDF–1.4M
15.
Pancreatic islet chromatin accessibility and conformation reveals distal enhancer networks of type 2 diabetes risk
William W. Greenwald, Joshua Chiou, Jian Yan, Yunjiang Qiu, Ning Dai, Allen Wang, Naoki Nariai, Anthony Aylward, Jee Yun Han, Nikita Kadakia, Laura Regue, Mei-Lin Okino, Frauke Drees, Dana Kramer, Nicholas Vinckier, Liliana Minichiello, David Gorkin, Joseph Avruch, Kelly A. Frazer, Maike Sander, Bing Ren, Kyle J. Gaulton
Nat Commun. 2019; 10: 2078. Published online 2019 May 7. doi: 10.1038/s41467-019-09975-4
PMCID:
PMC6505525
ArticlePDF–1.2M
16.
IMP2 Increases Mouse Skeletal Muscle Mass and Voluntary Activity by Enhancing Autocrine Insulin-Like Growth Factor 2 Production and Optimizing Muscle Metabolism
Laura Regué, Fei Ji, Daniel Flicker, Dana Kramer, William Pierce, Teekhon Davidoff, Jeffrey J. Widrick, Nicholas Houstis, Liliana Minichiello, Ning Dai, Joseph Avruch
Mol Cell Biol. 2019 Apr 1; 39(7): e00528-18. Prepublished online 2019 Jan 28. Published online 2019 Mar 19. doi: 10.1128/MCB.00528-18
PMCID:
PMC6425142
ArticlePDF–3.1M
17.
The insulin-like growth factor 2 (IGF2) mRNA-binding protein p62/IGF2BP2-2 as a promoter of NAFLD and HCC?
Yvette Simon, Sonja M Kessler, Rainer M Bohle, Johannes Haybaeck, Alexandra K Kiemer
Gut. 2014 May; 63(5): 861–863. Published online 2013 Oct 30. doi: 10.1136/gutjnl-2013-305736
PMCID:
PMC3995267
ArticlePDF–4.5M
18.
An HMGA2-IGF2BP2 Axis Regulates Myoblast Proliferation and Myogenesis
Zhizhong Li, Jason A. Gilbert, Yunyu Zhang, Minsi Zhang, Qiong Qiu, Krishnan Ramanujan, Tea Shavlakadze, John K. Eash, Annarita Scaramozza, Matthew M. Goddeeris, David G. Kirsch, Kevin P. Campbell, Andrew S. Brack, David J. Glass
Dev Cell. Author manuscript; available in PMC 2013 May 6.
Published in final edited form as: Dev Cell. 2012 Dec 11; 23(6): 1176–1188. Published online 2012 Nov 21. doi: 10.1016/j.devcel.2012.10.019
Correction in:
volume 24 on page 112
PMCID:
PMC3645921
ArticlePDF–2.8M
19.
Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells
Michalina Janiszewska, Mario L. Suvà, Nicolo Riggi, Riekelt H. Houtkooper, Johan Auwerx, Virginie Clément-Schatlo, Ivan Radovanovic, Esther Rheinbay, Paolo Provero, Ivan Stamenkovic
Genes Dev. 2012 Sep 1; 26(17): 1926–1944. doi: 10.1101/gad.188292.112
PMCID:
PMC3435496
ArticlePDF–1.9M
20.
FBW7/GSK3β mediated degradation of IGF2BP2 inhibits IGF2BP2-SLC7A5 positive feedback loop and radioresistance in lung cancer
Zhiyuan Zhou, Bin Zhang, Yue Deng, Suke Deng, Jie Li, Wenwen Wei, Yijun Wang, Jiacheng Wang, Zishan Feng, Mengjie Che, Xiao Yang, Jingshu Meng, Yan Li, Yan Hu, Yajie Sun, Lu Wen, Fang Huang, Yuhan Sheng, Chao Wan, Kunyu Yang
J Exp Clin Cancer Res. 2024; 43: 34. Published online 2024 Jan 29. doi: 10.1186/s13046-024-02959-3
PMCID:
PMC10823633
ArticlePDF–10M

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