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Select item 91339501.

Neuroprotective effect of Ginsenoside Re against neurotoxin-induced Parkinson's disease models via induction of Nrf2

Juhui Qiao, Yuchu Zhao, Ying Liu, Siyu Zhang, Wenxue Zhao, Shichao Liu, Meichen Liu

Mol Med Rep. 2022 Jun; 25(6): 215. Published online 2022 May 9. doi: 10.3892/mmr.2022.12731

PMCID:: PMC9133950

Article PDF–6.3M

Select item 81154442.

Cruciferous vegetables (Brassica oleracea) confer cytoprotective effects in Drosophila intestines

James T. Lyles, Liping Luo, Ken Liu, Dean P. Jones, Rheinallt M. Jones, Cassandra L. Quave

Gut Microbes. 2021; 13(1): 1921926. Published online 2021 May 8. doi: 10.1080/19490976.2021.1921926

PMCID:: PMC8115444

Article PDF–2.1M

Select item 55001473.

Cap-n-Collar Promotes Tissue Regeneration by Regulating ROS and JNK Signaling in the Drosophila melanogaster Wing Imaginal Disc

Amanda R. Brock, Mabel Seto, Rachel K. Smith-Bolton

Genetics. 2017 Jul; 206(3): 1505–1520. Published online 2017 May 15. doi: 10.1534/genetics.116.196832

PMCID:: PMC5500147

Article PDF–2.1M

Select item 48378974.

Beyond antioxidant genes in the ancient NRF2 regulatory network

Sarah E. Lacher, Joslynn S. Lee, Xuting Wang, Michelle R. Campbell, Douglas A. Bell, Matthew Slattery

Free Radic Biol Med. Author manuscript; available in PMC 2016 Apr 20.

Published in final edited form as: Free Radic Biol Med. 2015 Nov; 88(Pt B): 452–465. Published online 2015 Jul 8. doi: 10.1016/j.freeradbiomed.2015.06.044

PMCID:: PMC4837897

Article PDF–1016K

Select item 105910935.

Changes in heme oxygenase level during development affect the adult life of Drosophila melanogaster

Bernadetta Bilska, Milena Damulewicz, Terence Al L. Abaquita, Elzbieta Pyza

Front Cell Neurosci. 2023; 17: 1239101. Published online 2023 Oct 9. doi: 10.3389/fncel.2023.1239101

PMCID:: PMC10591093

Article PDF–13M

Select item 96523706.

Oxidative stress mediates end-organ damage in a novel model of acetaminophen-toxicity in Drosophila

Bejan J. Saeedi, Sarah Hunter-Chang, Liping Luo, Kaiyan Li, Ken H. Liu, Brian S. Robinson

Sci Rep. 2022; 12: 19309. Published online 2022 Nov 11. doi: 10.1038/s41598-022-21156-w

PMCID:: PMC9652370

Article PDF–2.4M

Select item 84035997.

Variation in resistance to oxidative stress in Oregon-(R)R-flare and Canton-S strains of Drosophila melanogaster

Santiago Cristobal Sigrist-Flores, Laura Castañeda-Partida, Myriam Campos-Aguilar, Luis Felipe Santos-Cruz, Aranza Miranda-Gutierrez, I A Gallardo-Ortíz, R Villalobos-Molina, Irma Elena Dueñas-García, María Eugenia Heres-Pulido, Elías Piedra-Ibarra, Víctor Hugo Rosales-García, Rafael Jimenez-Flores, Alberto Ponciano-Gómez

Toxicol Res (Camb) 2021 Aug; 10(4): 817–823. Published online 2021 Jul 22. doi: 10.1093/toxres/tfab066

PMCID:: PMC8403599

Article PDF–792K

Select item 83945288.

Activation of Nrf2 in Astrocytes Suppressed PD-Like Phenotypes via Antioxidant and Autophagy Pathways in Rat and Drosophila Models

Qing Guo, Bing Wang, Xiaobo Wang, Wanli W. Smith, Yi Zhu, Zhaohui Liu

Cells. 2021 Aug; 10(8): 1850. Published online 2021 Jul 21. doi: 10.3390/cells10081850

PMCID:: PMC8394528

Article PDF–5.0M

Select item 64769609.

Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity

Jereme G. Spiers, Carlo Breda, Sue Robinson, Flaviano Giorgini, Joern R. Steinert

Front Mol Neurosci. 2019; 12: 86. Published online 2019 Apr 16. doi: 10.3389/fnmol.2019.00086

PMCID:: PMC6476960

Article PDF–3.0M

Select item 621528210.

Copper Oxide Nanoparticles Cause a Dose-Dependent Toxicity via Inducing Reactive Oxygen Species in Drosophila

Eugene Baeg, Kanidta Sooklert, Amornpun Sereemaspun

Nanomaterials (Basel) 2018 Oct; 8(10): 824. Published online 2018 Oct 12. doi: 10.3390/nano8100824

PMCID:: PMC6215282

Article PDF–2.5M

Select item 533901311.

Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster

Cheng Teng Ng, Liang Qing Yong, Manoor Prakash Hande, Choon Nam Ong, Liya E Yu, Boon Huat Bay, Gyeong Hun Baeg

Int J Nanomedicine. 2017; 12: 1621–1637. Published online 2017 Feb 28. doi: 10.2147/IJN.S124403

PMCID:: PMC5339013

Article PDF–12M

Select item 533380112.

Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease

Fiona Kerr, Oyinkan Sofola-Adesakin, Dobril K. Ivanov, Jemma Gatliff, Beatriz Gomez Perez-Nievas, Hélène C. Bertrand, Pedro Martinez, Rebecca Callard, Inge Snoeren, Helena M. Cochemé, Jennifer Adcott, Mobina Khericha, Jorge Iván Castillo-Quan, Geoffrey Wells, Wendy Noble, Janet Thornton, Linda Partridge

PLoS Genet. 2017 Mar; 13(3): e1006593. Published online 2017 Mar 2. doi: 10.1371/journal.pgen.1006593

PMCID:: PMC5333801

Article PDF–6.2M

Select item 397489713.

Multiple roles of Nrf2-Keap1 signaling: Regulation of development and xenobiotic response using distinct mechanisms

Huai Deng

Fly (Austin) 2014 Jan 1; 8(1): 7–12. Published online 2013 Nov 1. doi: 10.4161/fly.27007

PMCID:: PMC3974897

Article PDF–873K

Select item 384246714.

Decaffeinated Coffee and Nicotine-Free Tobacco Provide Neuroprotection in Drosophila Models of Parkinson's Disease through an NRF2-Dependent Mechanism

Kien Trinh, Laurie Andrews, James Krause, Tyler Hanak, Daewoo Lee, Michael Gelb, Leo Pallanck

J Neurosci. 2010 Apr 21; 30(16): 5525–5532. doi: 10.1523/JNEUROSCI.4777-09.2010

PMCID:: PMC3842467

Article PDF–1.6M

Select item 317571615.

Transcriptional regulation of xenobiotic detoxification in Drosophila

Jyoti R. Misra, Michael A. Horner, Geanette Lam, Carl S. Thummel

Genes Dev. 2011 Sep 1; 25(17): 1796–1806. doi: 10.1101/gad.17280911

PMCID:: PMC3175716

Article PDF–1.1M

Select item 1004769816.

Determination of Complex Formation between Drosophila Nrf2 and GATA4 Factors at Selective Chromatin Loci Demonstrates Transcription Coactivation

Emma Neidviecky, Huai Deng

Cells. 2023 Mar; 12(6): 938. Published online 2023 Mar 19. doi: 10.3390/cells12060938

PMCID:: PMC10047698

Article PDF–1.9M

Select item 970807417.

Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model

Deeptiman Chatterjee, Caique Almeida Machado Costa, Xian-Feng Wang, Allison Jevitt, Yi-Chun Huang, Wu-Min Deng

eLife. 2022; 11: e80956. Published online 2022 Nov 2. doi: 10.7554/eLife.80956

PMCID:: PMC9708074

Article PDF–14M

Select item 866001918.

Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease

Yu-En Lin, Chin-Hsien Lin, En-Peng Ho, Yi-Ci Ke, Stavroula Petridi, Christopher JH Elliott, Lee-Yan Sheen, Cheng-Ting Chien

eLife. 2021; 10: e73753. Published online 2021 Nov 15. doi: 10.7554/eLife.73753

PMCID:: PMC8660019

Article PDF–5.0M

Select item 764167119.

CG8005 Mediates Transit-Amplifying Spermatogonial Divisions via Oxidative Stress in Drosophila Testes

Wanyin Chen, Xiaojin Luan, Yidan Yan, Min Wang, Qianwen Zheng, Xia Chen, Jun Yu, Jie Fang

Oxid Med Cell Longev. 2020; 2020: 2846727. Published online 2020 Oct 27. doi: 10.1155/2020/2846727

PMCID:: PMC7641671

Article PDF–5.4M

Select item 732906820.

Gut-Resident Lactobacilli Activate Hepatic Nrf2 and Protect Against Oxidative Liver Injury

Bejan J. Saeedi, Ken H. Liu, Joshua A. Owens, Sarah Hunter-Chang, Mary C. Camacho, Richard U. Eboka, Bindu Chandrasekharan, Nusaiba F. Baker, Trevor M. Darby, Brian S. Robinson, Rheinallt M. Jones, Dean P. Jones, Andrew S. Neish

Cell Metab. Author manuscript; available in PMC 2021 May 5.

Published in final edited form as: Cell Metab. 2020 May 5; 31(5): 956–968.e5. Published online 2020 Mar 25. doi: 10.1016/j.cmet.2020.03.006