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Select item 95502191.

A human iPSC-array-based GWAS identifies a virus susceptibility locus in the NDUFA4 gene and functional variants

Yuling Han, Lei Tan, Ting Zhou, Liuliu Yang, Lucia Carrau, Lauretta A. Lacko, Mohsan Saeed, Jiajun Zhu, Zeping Zhao, Benjamin E. Nilsson-Payant, Filipe Tenorio Lira Neto, Clare Cahir, Alice Maria Giani, Jin Chou Chai, Yang Li, Xue Dong, Dorota Moroziewicz, The NYSCF Global Stem Cell Array Team, Daniel Paull, Tuo Zhang, Soyeon Koo, Christina Tan, Ron Danziger, Qian Ba, Lingling Feng, Zhengming Chen, Aaron Zhong, Gilbert J. Wise, Jenny Z. Xiang, Hui Wang, Robert E. Schwartz, Benjamin R. tenOever, Scott A. Noggle, Charles M. Rice, Qibin Qi, Todd Evans, Shuibing Chen

Cell Stem Cell. 2022 Oct 6; 29(10): 1475–1490.e6. doi: 10.1016/j.stem.2022.09.008

PMCID:: PMC9550219

Article PDF–7.1M

Select item 93857012.

m6A RNA methylation-mediated NDUFA4 promotes cell proliferation and metabolism in gastric cancer

Weihong Xu, Yanan Lai, Yunqi Pan, Meiyu Tan, Yanyun Ma, Huiming Sheng, Jiucun Wang

Cell Death Dis. 2022 Aug; 13(8): 715. Published online 2022 Aug 17. doi: 10.1038/s41419-022-05132-w

PMCID:: PMC9385701

Article PDF–5.6M

Select item 37013213.

NDUFA4 Mutations Underlie Dysfunction of a Cytochrome c Oxidase Subunit Linked to Human Neurological Disease

Robert D.S. Pitceathly, Shamima Rahman, Yehani Wedatilake, James M. Polke, Sebahattin Cirak, A. Reghan Foley, Anna Sailer, Matthew E. Hurles, Jim Stalker, Iain Hargreaves, Cathy E. Woodward, Mary G. Sweeney, Francesco Muntoni, Henry Houlden, UK10K Consortium, Jan-Willem Taanman, Michael G. Hanna

Cell Rep. 2013 Jun 27; 3(6): 1795–1805. doi: 10.1016/j.celrep.2013.05.005

Correction in:: Cell Rep. 2013 Jul 25; 4(2): 402.

PMCID:: PMC3701321

Article

Select item 80353214.

Coding and non-coding roles of MOCCI (C15ORF48) coordinate to regulate host inflammation and immunity

Cheryl Q. E. Lee, Baptiste Kerouanton, Sonia Chothani, Shan Zhang, Ying Chen, Chinmay Kumar Mantri, Daniella Helena Hock, Radiance Lim, Rhea Nadkarni, Vinh Thang Huynh, Daryl Lim, Wei Leong Chew, Franklin L. Zhong, David Arthur Stroud, Sebastian Schafer, Vinay Tergaonkar, Ashley L. St John, Owen J. L. Rackham, Lena Ho

Nat Commun. 2021; 12: 2130. Published online 2021 Apr 9. doi: 10.1038/s41467-021-22397-5

PMCID:: PMC8035321

Article PDF–4.7M

Select item 62720885.

Long non‐coding RNA MIF‐AS1 promotes gastric cancer cell proliferation and reduces apoptosis to upregulate NDUFA4

Linhai Li, Yuejin Li, Yingguang Huang, Yiming Ouyang, Yu Zhu, Yongzhi Wang, Xiaodong Guo, Ying Yuan, Kunmei Gong

Cancer Sci. 2018 Dec; 109(12): 3714–3725. Published online 2018 Oct 31. doi: 10.1111/cas.13801

PMCID:: PMC6272088

Article PDF–1.4M

Select item 45607656.

Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway

Wei Song, Wenjie Liu, Hong Zhao, Shangze Li, Xin Guan, Jianming Ying, Yefan Zhang, Fei Miao, Mengmeng Zhang, Xiaoxia Ren, Xiaolu Li, Fan Wu, Yuechao Zhao, Yuanyuan Tian, Wenming Wu, Jun Fu, Junbo Liang, Wei Wu, Changzheng Liu, Jia Yu, Shudong Zong, Shiying Miao, Xiaodong Zhang, Linfang Wang

Nat Commun. 2015; 6: 8022. Published online 2015 Aug 24. doi: 10.1038/ncomms9022

PMCID:: PMC4560765

Article PDF–4.2M

Select item 61704087.

Structure of the intact 14-subunit human cytochrome c oxidase

Shuai Zong, Meng Wu, Jinke Gu, Tianya Liu, Runyu Guo, Maojun Yang

Cell Res. 2018 Oct; 28(10): 1026–1034. Published online 2018 Jul 20. doi: 10.1038/s41422-018-0071-1

PMCID:: PMC6170408

Article PDF–4.9M

Select item 44618378.

Inhibition of the mitochondrial protease, ClpP, as a therapeutic strategy for human acute myeloid leuekmia

Alicia Cole, Zezhou Wang, Etienne Coyaud, Veronique Voisin, Marcela Gronda, Yulia Jitkova, Rachel Mattson, Rose Hurren, Sonja Babovic, Neil Maclean, Ian Restall, Xiaoming Wang, Danny V. Jeyaraju, Mahadeo A. Sukhai, Swayam Prabha, Shaheena Bashir, Ashwin Ramakrishnan, Elisa Leung, Yi Hua Qia, Nianxian Zhang, Kevin R. Combes, Troy Ketela, Fengshu Lin, Walid A. Houry, Ahmed Aman, Rima Al-awar, Wei Zheng, Erno Wienholds, Chang Jiang Xu, John Dick, Jean C.Y. Wang, Jason Moffat, Mark D. Minden, Connie J. Eaves, Gary D. Bader, Zhenyue Hao, Steven M. Kornblau, Brian Raught, Aaron D. Schimmer

Cancer Cell. Author manuscript; available in PMC 2016 Jun 8.

Published in final edited form as: Cancer Cell. 2015 Jun 8; 27(6): 864–876. doi: 10.1016/j.ccell.2015.05.004

PMCID:: PMC4461837

Article PDF–2.3M

Select item 93459699.

Targeted inhibition of ubiquitin signaling reverses metabolic reprogramming and suppresses glioblastoma growth

Rossella Delle Donne, Rosa Iannucci, Laura Rinaldi, Luca Roberto, Maria A. Oliva, Emanuela Senatore, Domenica Borzacchiello, Luca Lignitto, Giorgio Giurato, Francesca Rizzo, Assunta Sellitto, Francesco Chiuso, Salvatore Castaldo, Giovanni Scala, Virginia Campani, Valeria Nele, Giuseppe De Rosa, Chiara D’Ambrosio, Corrado Garbi, Andrea Scaloni, Alessandro Weisz, Concetta Ambrosino, Antonella Arcella, Antonio Feliciello

Commun Biol. 2022; 5: 780. Published online 2022 Aug 2. doi: 10.1038/s42003-022-03639-8

PMCID:: PMC9345969

Article PDF–2.3M

Select item 351821910.

KIF14 negatively regulates Rap1a–Radil signaling during breast cancer progression

Syed M. Ahmed, Brigitte L. Thériault, Maruti Uppalapati, Catherine W.N. Chiu, Brenda L. Gallie, Sachdev S. Sidhu, Stéphane Angers

J Cell Biol. 2012 Dec 10; 199(6): 951–967. doi: 10.1083/jcb.201206051

PMCID:: PMC3518219

Article PDF–3.7M

Select item 713853711.

Loss-of-Function Variants in TBC1D32 Underlie Syndromic Hypopituitarism

Johanna Hietamäki, Louise C Gregory, Sandy Ayoub, Anna-Pauliina Iivonen, Kirsi Vaaralahti, Xiaonan Liu, Nina Brandstack, Andrew J Buckton, Tiina Laine, Johanna Känsäkoski, Matti Hero, Päivi J Miettinen, Markku Varjosalo, Emma Wakeling, Mehul T Dattani, Taneli Raivio

J Clin Endocrinol Metab. 2020 Jun; 105(6): 1748–1758. Published online 2020 Feb 15. doi: 10.1210/clinem/dgaa078

PMCID:: PMC7138537

Article

Select item 558980012.

SOCS2 Binds to and Regulates EphA2 through Multiple Mechanisms

Carissa Pilling, Jonathan A. Cooper

Sci Rep. 2017; 7: 10838. Published online 2017 Sep 7. doi: 10.1038/s41598-017-11040-3

PMCID:: PMC5589800

Article PDF–5.5M

Select item 402382513.

TIMMDC1/C3orf1 Functions as a Membrane-Embedded Mitochondrial Complex I Assembly Factor through Association with the MCIA Complex

Virginia Guarani, Joao Paulo, Bo Zhai, Edward L. Huttlin, Steven P. Gygi, J. Wade Harper

Mol Cell Biol. 2014 Mar; 34(5): 847–861. doi: 10.1128/MCB.01551-13

PMCID:: PMC4023825

Article PDF–5.5M

Select item 470913614.

FIH Regulates Cellular Metabolism through Hydroxylation of the Deubiquitinase OTUB1

Carsten C. Scholz, Javier Rodriguez, Christina Pickel, Stephen Burr, Jacqueline-alba Fabrizio, Karen A. Nolan, Patrick Spielmann, Miguel A. S. Cavadas, Bianca Crifo, Doug N. Halligan, James A. Nathan, Daniel J. Peet, Roland H. Wenger, Alex Von Kriegsheim, Eoin P. Cummins, Cormac T. Taylor

PLoS Biol. 2016 Jan; 14(1): e1002347. Published online 2016 Jan 11. doi: 10.1371/journal.pbio.1002347

PMCID:: PMC4709136

Article PDF–2.3M

Select item 583958515.

Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis

Afrooz Dabbaghizadeh, Geneviève Morrow, Yasmine Ould Amer, Etienne Hebert Chatelain, Nicolas Pichaud, Robert M. Tanguay

PLoS One. 2018; 13(3): e0193771. Published online 2018 Mar 6. doi: 10.1371/journal.pone.0193771

PMCID:: PMC5839585

Article PDF–15M

Select item 542795016.

Novel, Gel-free Proteomics Approach Identifies RNF5 and JAMP as Modulators of GPCR Stability

Sébastien J. Roy, Irina Glazkova, Louis Fréchette, Christian Iorio-Morin, Chantal Binda, Darlaine Pétrin, Phan Trieu, Mélanie Robitaille, Stéphane Angers, Terence E. Hébert, Jean-Luc Parent

Mol Endocrinol. 2013 Aug; 27(8): 1245–1266. Published online 2013 Jun 24. doi: 10.1210/me.2013-1091

PMCID:: PMC5427950

Article

Select item 637966917.

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex

Danton Ivanochko, Levon Halabelian, Elizabeth Henderson, Pavel Savitsky, Harshika Jain, Edyta Marcon, Shili Duan, Ashley Hutchinson, Alma Seitova, Dalia Barsyte-Lovejoy, Panagis Filippakopoulos, Jack Greenblatt, Evelyne Lima-Fernandes, Cheryl H Arrowsmith

Nucleic Acids Res. 2019 Feb 20; 47(3): 1225–1238. Published online 2018 Nov 20. doi: 10.1093/nar/gky1192

PMCID:: PMC6379669

Article PDF–7.5M

Select item 431995118.

ABCE1 Is a Highly Conserved RNA Silencing Suppressor

Kairi Kärblane, Jelena Gerassimenko, Lenne Nigul, Alla Piirsoo, Agata Smialowska, Kadri Vinkel, Per Kylsten, Karl Ekwall, Peter Swoboda, Erkki Truve, Cecilia Sarmiento

PLoS One. 2015; 10(2): e0116702. Published online 2015 Feb 6. doi: 10.1371/journal.pone.0116702

PMCID:: PMC4319951

Article PDF–2.8M

Select item 353489119.

SGTA recognizes a non-canonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote ER-associated degradation

Yue Xu, Mengli Cai, Yingying Yang, Lan Huang, Yihong Ye

Cell Rep. Author manuscript; available in PMC 2013 Jan 3.

Published in final edited form as: Cell Rep. 2012 Dec 27; 2(6): 1633–1644. Published online 2012 Dec 13. doi: 10.1016/j.celrep.2012.11.010

PMCID:: PMC3534891

Article PDF–3.0M

Select item 628329320.

Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies

Christina Schiza, Dimitrios Korbakis, Efstratia Panteleli, Keith Jarvi, Andrei P. Drabovich, Eleftherios P. Diamandis

Mol Cell Proteomics. 2018 Dec; 17(12): 2480–2495. Published online 2018 Aug 10. doi: 10.1074/mcp.RA118.000749

PMCID:: PMC6283293

Article PDF–1.9M

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