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Select item 76543961.

Role of nuclear factor of activated T cells 2 (NFATc2) in allergic asthma

Marielena Jakobi, Alexander Kiefer, Hooman Mirzakhani, Manfred Rauh, Theodor Zimmermann, Paraskevi Xepapadaki, Barbara Stanic, Mubeccel Akdis, Nikolaos G. Papadopoulos, Benjamin A. Raby, Scott T. Weiss, Susetta Finotto

Immun Inflamm Dis. 2020 Dec; 8(4): 704–712. Published online 2020 Oct 20. doi: 10.1002/iid3.360

PMCID:: PMC7654396

Abstract Article PDF–934K

Select item 64355082.

NFAT1 enhances the effects of tumor-associated macrophages on promoting malignant melanoma growth and metastasis

Hao Liu, Liping Yang, Min Qi, Jianglin Zhang

Biosci Rep. 2018 Dec 21; 38(6): BSR20181604. Prepublished online 2018 Nov 20. Published online 2018 Dec 18. doi: 10.1042/BSR20181604

PMCID:: PMC6435508

Abstract Article PDF–2.7M

Select item 58286093.

¹⁵N detection harnesses the slow relaxation property of nitrogen: Delivering enhanced resolution for intrinsically disordered proteins

Sandeep Chhabra, Patrick Fischer, Koh Takeuchi, Abhinav Dubey, Joshua J. Ziarek, Andras Boeszoermenyi, Daniel Mathieu, Wolfgang Bermel, Norman E. Davey, Gerhard Wagner, Haribabu Arthanari

Proc Natl Acad Sci U S A. 2018 Feb 20; 115(8): E1710–E1719. Published online 2018 Feb 5. doi: 10.1073/pnas.1717560115

PMCID:: PMC5828609

Abstract Article PDF–1.6M

Select item 48614404.

Up-regulation of Store-operated Ca²⁺ Entry and Nuclear Factor of Activated T Cells Promote the Acinar Phenotype of the Primary Human Salivary Gland Cells

Shyh-Ing Jang, Hwei Ling Ong, Xibao Liu, Ilias Alevizos, Indu S. Ambudkar

J Biol Chem. 2016 Apr 15; 291(16): 8709–8720. Published online 2016 Feb 22. doi: 10.1074/jbc.M115.701607

PMCID:: PMC4861440

Abstract Article PDF–1.6M

Select item 45239535.

Nuclear factor of activated T-cell isoform expression and regulation in human myometrium

Evonne C. Chin-Smith, Frances R. Willey, Donna M. Slater, Michael J. Taggart, Rachel M. Tribe

Reprod Biol Endocrinol. 2015; 13: 83. Published online 2015 Aug 4. doi: 10.1186/s12958-015-0086-0

PMCID:: PMC4523953

Abstract Article PDF–1.0M

Select item 44921976.

Genome-wide analysis links NFATC2 with asparaginase hypersensitivity

Christian A. Fernandez, Colton Smith, Wenjian Yang, Charles G. Mullighan, Chunxu Qu, Eric Larsen, W. Paul Bowman, Chengcheng Liu, Laura B. Ramsey, Tamara Chang, Seth E. Karol, Mignon L. Loh, Elizabeth A. Raetz, Naomi J. Winick, Stephen P. Hunger, William L. Carroll, Sima Jeha, Ching-Hon Pui, William E. Evans, Meenakshi Devidas, Mary V. Relling

Blood. 2015 Jul 2; 126(1): 69–75. Prepublished online 2015 May 18. doi: 10.1182/blood-2015-02-628800

PMCID:: PMC4492197

Abstract Article

Select item 40182107.

Nuclear translocation of Nuclear Factor of Activated T cells (NFAT) as a quantitative pharmacodynamic parameter for tacrolimus

Orla Maguire, Kathleen M. Tornatore, Kieran L. O'Loughlin, Rocco C. Venuto, Hans Minderman

Cytometry A. Author manuscript; available in PMC 2014 Dec 1.

Published in final edited form as: Cytometry A. 2013 Dec; 83(12): 1096–1104. Published online 2013 Oct 17. doi: 10.1002/cyto.a.22401

PMCID:: PMC4018210

Abstract Article PDF–555K

Select item 36752088.

NFAT1 Is Highly Expressed in, and Regulates the Invasion of, Glioblastoma Multiforme Cells

Xinxin Tie, Sheng Han, Lingxuan Meng, Yunjie Wang, Anhua Wu

PLoS One. 2013; 8(6): e66008. Published online 2013 Jun 6. doi: 10.1371/journal.pone.0066008

PMCID:: PMC3675208

Abstract Article PDF–1.6M

Select item 31906849.

Disruption of a Nuclear NFATc2 Protein Stabilization Loop Confers Breast and Pancreatic Cancer Growth Suppression by Zoledronic Acid

Shiv K. Singh, Sandra Baumgart, Garima Singh, Alexander O. König, Kristina Reutlinger, Lorenz C. Hofbauer, Peter Barth, Thomas M. Gress, Gwen Lomberk, Raul Urrutia, Martin E. Fernandez-Zapico, Volker Ellenrieder

J Biol Chem. 2011 Aug 19; 286(33): 28761–28771. Published online 2011 May 31. doi: 10.1074/jbc.M110.197533

PMCID:: PMC3190684

Abstract Article PDF–3.5M

Select item 308320810.

Selective Activation of the Transcription Factor NFAT1 by Calcium Microdomains near Ca²⁺ Release-activated Ca²⁺ (CRAC) Channels

Pulak Kar, Charmaine Nelson, Anant B. Parekh

J Biol Chem. 2011 Apr 29; 286(17): 14795–14803. Published online 2011 Feb 16. doi: 10.1074/jbc.M111.220582

PMCID:: PMC3083208

Abstract Article PDF–3.7M

Select item 306418311.

Minocycline Suppresses Activation of Nuclear Factor of Activated T Cells 1 (NFAT1) in Human CD4⁺ T Cells

Gregory L. Szeto, Joel L. Pomerantz, David R. M. Graham, Janice E. Clements

J Biol Chem. 2011 Apr 1; 286(13): 11275–11282. Published online 2011 Jan 31. doi: 10.1074/jbc.M110.210518

PMCID:: PMC3064183

Abstract Article PDF–988K

Select item 290451212.

Wnt/Ca²⁺/NFAT signaling maintains survival of Ph⁺ leukemia cells upon inhibition of Bcr-Abl

Mark A. Gregory, Tzu L. Phang, Paolo Neviani, Francesca Alvarez-Calderon, Christopher A. Eide, Thomas O’Hare, Vadym Zaberezhnyy, Richard T. Williams, Brian J. Druker, Danilo Perrotti, James DeGregori

Cancer Cell. Author manuscript; available in PMC 2011 Jul 13.

Published in final edited form as: Cancer Cell. 2010 Jul 13; 18(1): 74–87. doi: 10.1016/j.ccr.2010.04.025

PMCID:: PMC2904512

Abstract Article PDF–1.4M

Select item 219400713.

Induction of NFATc2 Expression by Interleukin 6 Promotes T Helper Type 2 Differentiation

Sean Diehl, Chi-Wing Chow, Linda Weiss, Alois Palmetshofer, Thomas Twardzik, Laura Rounds, Edgar Serfling, Roger J. Davis, Juan Anguita, Mercedes Rincón

J Exp Med. 2002 Jul 1; 196(1): 39–49. doi: 10.1084/jem.20020026

PMCID:: PMC2194007

Abstract Article PDF–309K

Select item 219216714.

Activation and expression of the nuclear factors of activated T cells, NFATp and NFATc, in human natural killer cells: regulation upon CD16 ligand binding

J Exp Med. 1995 Sep 1; 182(3): 801–810. doi: 10.1084/jem.182.3.801

PMCID:: PMC2192167

Summary PDF–1.6M

Select item 23209615.

Expression of NFAT-family proteins in normal human T cells.

L Lyakh, P Ghosh, N R Rice

Mol Cell Biol. 1997 May; 17(5): 2475–2484. doi: 10.1128/mcb.17.5.2475

PMCID:: PMC232096

Summary PDF–1.2M

Select item 3134716.

Characterization of DNA binding, transcriptional activation, and regulated nuclear association of recombinant human NFATp

Loree J Kim, Heather A Ferguson, Anita G Seto, James A Goodrich

BMC Immunol. 2000; 1: 1. Published online 2000 Nov 6. doi: 10.1186/1471-2172-1-1

PMCID:: PMC31347

Abstract Article PDF–890K

Select item 1080193617.

Report and literature review of four cases of EWSR1::NFATC2 round cell sarcoma

Lili Liu, Lan Li, Yi Ding, Fangzhou Kong, Wenfa Mo, Hongtao Ye, Danhua Shen

Diagn Pathol. 2024; 19: 19. Published online 2024 Jan 22. doi: 10.1186/s13000-024-01443-y

PMCID:: PMC10801936

Abstract Article PDF–2.3M

Select item 958656718.

Genetic inhibition of nuclear factor of activated T-cell c2 prevents atrial fibrillation in CREM transgenic mice

Li Ni, Satadru K Lahiri, Jiali Nie, Xiaolu Pan, Issam Abu-Taha, Julia O Reynolds, Hannah M Campbell, Haihao Wang, Markus Kamler, Wilhelm Schmitz, Frank Ulrich Müller, Na Li, Xiang Wei, Dao Wen Wang, Dobromir Dobrev, Xander H T Wehrens

Cardiovasc Res. 2022 Sep; 118(13): 2805–2818. Published online 2021 Oct 14. doi: 10.1093/cvr/cvab325

PMCID:: PMC9586567

Abstract Article PDF–1.6M

Select item 859811119.

Expanding the Spectrum of EWSR1-NFATC2-rearranged Benign Tumors: A Common Genomic Abnormality in Vascular Malformation/Hemangioma and Simple Bone Cyst

Sheena L.M. Ong, Suk Wai Lam, Brendy E.W.M. van den Akker, Herman M. Kroon, Inge H. Briaire-de Bruijn, Arjen H.G. Cleven, Dilara C. Savci-Heijink, Anne-Marie Cleton-Jansen, Daniel Baumhoer, Karoly Szuhai, Judith V.M.G. Bovée

Am J Surg Pathol. 2021 Dec; 45(12): 1669–1681. Published online 2021 Jun 3. doi: 10.1097/PAS.0000000000001748

PMCID:: PMC8598111

Abstract Article PDF–1.0M

Select item 855356920.

Identification of direct transcriptional targets of NFATC2 that promote β cell proliferation

Shane P. Simonett, Sunyoung Shin, Jacob A. Herring, Rhonda Bacher, Linsin A. Smith, Chenyang Dong, Mary E. Rabaglia, Donnie S. Stapleton, Kathryn L. Schueler, Jeea Choi, Matthew N. Bernstein, Daniel R. Turkewitz, Carlos Perez-Cervantes, Jason Spaeth, Roland Stein, Jeffery S. Tessem, Christina Kendziorski, Sündüz Keleş, Ivan P. Moskowitz, Mark P. Keller, Alan D. Attie

J Clin Invest. 2021 Nov 1; 131(21): e144833. Published online 2021 Nov 1. doi: 10.1172/JCI144833

PMCID:: PMC8553569

Abstract Article PDF–2.7M

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