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Items: 1 to 20 of 47

1.
In a multi-institutional cohort of myeloid sarcomas, NFE2 mutation prevalence is lower than previously reported
Tauangtham Anekpuritanang, Matthew M. Klairmont, Joel Gradowski, Kohei Hagiwara, Nathanael G. Bailey, Pranil Chandra, Yiwei Liu, Heather L. Mulder, John Easton, Jinghui Zhang, Michael G. Martin, Anna B. Owczarczyk, Jennifer B. Dunlap, Guang Fan, Richard D. Press, Philipp W. Raess
Blood Adv. 2021 Dec 14; 5(23): 5057–5059. Published online 2021 Dec 3. doi: 10.1182/bloodadvances.2021004983
PMCID:
PMC9152993
ArticlePDF–579K
2.
A novel role for nuclear factor-erythroid 2 in erythroid maturation by modulation of mitochondrial autophagy
Monika Gothwal, Julius Wehrle, Konrad Aumann, Vanessa Zimmermann, Albert Gründer, Heike L. Pahl
Haematologica. 2016 Sep; 101(9): 1054–1064. doi: 10.3324/haematol.2015.132589
PMCID:
PMC5060022
AbstractArticlePDF–2.6M
3.
Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates prefibrotic primary myelofibrosis from essential thrombocythemia
Konrad Aumann, Anna-Verena Frey, Annette M. May, Dieter Hauschke, Clemens Kreutz, Jan P. Marx, Jens Timmer, Martin Werner, Heike L. Pahl
Blood. 2013 Jul 4; 122(1): 93–99. Prepublished online 2013 May 13. doi: 10.1182/blood-2012-11-463257
PMCID:
PMC3701907
AbstractArticle
4.
Elevated Nuclear Factor Erythroid-2 Levels Promote Epo-Independent Erythroid Maturation and Recapitulate the Hematopoietic Stem Cell and Common Myeloid Progenitor Expansion Observed in Polycythemia Vera Patients
Ruzhica Bogeska, Heike L. Pahl
Stem Cells Transl Med. 2013 Feb; 2(2): 112–117. Published online 2013 Jan 22. doi: 10.5966/sctm.2012-0046
PMCID:
PMC3659758
AbstractArticlePDF–2.3M
5.
MPN patients harbor recurrent truncating mutations in transcription factor NF-E2
Jonas S. Jutzi, Ruzhica Bogeska, Gorica Nikoloski, Corina A. Schmid, Thalia S. Seeger, Frank Stegelmann, Sven Schwemmers, Albert Gründer, Jan C. Peeken, Monika Gothwal, Julius Wehrle, Konrad Aumann, Kamar Hamdi, Christine Dierks, Wei Wang, Konstanze Döhner, Joop H. Jansen, Heike L. Pahl
J Exp Med. 2013 May 6; 210(5): 1003–1019. doi: 10.1084/jem.20120521
PMCID:
PMC3646501
AbstractArticlePDF–4.3M
6.
A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2
Kai B. Kaufmann, Albert Gründer, Tobias Hadlich, Julius Wehrle, Monika Gothwal, Ruzhica Bogeska, Thalia S. Seeger, Sarah Kayser, Kien-Binh Pham, Jonas S. Jutzi, Lucas Ganzenmüller, Doris Steinemann, Brigitte Schlegelberger, Julia M. Wagner, Manfred Jung, Britta Will, Ulrich Steidl, Konrad Aumann, Martin Werner, Thomas Günther, Roland Schüle, Alessandro Rambaldi, Heike L. Pahl
J Exp Med. 2012 Jan 16; 209(1): 35–50. doi: 10.1084/jem.20110540
PMCID:
PMC3260873
AbstractArticlePDF–3.6M
7.
An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer
Xiao-Song Wang, John R. Prensner, Guoan Chen, Qi Cao, Bo Han, Saravana M Dhanasekaran, Rakesh Ponnala, Xuhong Cao, Sooryanarayana Varambally, Dafydd G. Thomas, Thomas J. Giordano, David G. Beer, Nallasivam Palanisamy, Maureen A. Sartor, Gilbert S. Omenn, Arul M. Chinnaiyan
Nat Biotechnol. Author manuscript; available in PMC 2011 May 3.
Published in final edited form as: Nat Biotechnol. 2009 Nov; 27(11): 1005–1011. Published online 2009 Nov 1. doi: 10.1038/nbt.1584
PMCID:
PMC3086882
AbstractArticlePDF–2.6M
8.
Isolation of cDNA encoding the human NF-E2 protein.
J Y Chan, X L Han, Y W Kan
Proc Natl Acad Sci U S A. 1993 Dec 1; 90(23): 11366–11370. doi: 10.1073/pnas.90.23.11366
PMCID:
PMC47983
SummaryPage BrowsePDF–1.2M
9.
Isolation of a differentially regulated splicing isoform of human NF-E2.
C Pischedda, S Cocco, A Melis, M G Marini, Y W Kan, A Cao, P Moi
Proc Natl Acad Sci U S A. 1995 Apr 11; 92(8): 3511–3515. doi: 10.1073/pnas.92.8.3511
PMCID:
PMC42197
SummaryPage BrowsePDF–1.3M
10.
Altered NFE2 activity predisposes to leukemic transformation and myelosarcoma with AML-specific aberrations
Jonas Samuel Jutzi, Titiksha Basu, Maximilian Pellmann, Sandra Kaiser, Doris Steinemann, Mathijs A. Sanders, Adil S. A. Hinai, Annelieke Zeilemaker, Sarolta Bojtine Kovacs, Christoph Koellerer, Jenny Ostendorp, Konrad Aumann, Wei Wang, Emmanuel Raffoux, Bruno Cassinat, Lars Bullinger, Brigitte Schlegelberger, Peter J. M. Valk, Heike Luise Pahl
Blood. 2019 Apr 18; 133(16): 1766–1777. Prepublished online 2019 Feb 12. doi: 10.1182/blood-2018-09-875047
PMCID:
PMC6484461
AbstractArticle
11.
Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation
Alessandro Di Tullio, Diana Passaro, Kevin Rouault-Pierre, Sukhveer Purewal, Dominique Bonnet
Stem Cell Reports. 2017 Jul 11; 9(1): 5–11. Published online 2017 Jun 22. doi: 10.1016/j.stemcr.2017.05.027
PMCID:
PMC5511106
AbstractArticlePDF–1.1M
12.
p45 NF-E2 regulates syncytiotrophoblast differentiation by post-translational GCM1 modifications in human intrauterine growth restriction
Shrey Kohli, Juliane Hoffmann, Franziska Lochmann, Paulina Markmeyer, Hanna Huebner, Fabian B Fahlbusch, Moh'd Mohanad Al-Dabet, Ihsan Gadi, Jayakumar Manoharan, Michael Löttge, Ana C Zenclussen, Anat Aharon, Benjamin Brenner, Khurrum Shahzad, Matthias Ruebner, Berend Isermann
Cell Death Dis. 2017 Apr; 8(4): e2730. Published online 2017 Apr 6. doi: 10.1038/cddis.2017.127
PMCID:
PMC5477575
AbstractArticlePDF–2.4M
13.
RUNX1 and NF-E2 upregulation is not specific for MPNs, but is seen in polycythemic disorders with augmented HIF signaling
Katarina Kapralova, Lucie Lanikova, Felipe Lorenzo, Jihyun Song, Monika Horvathova, Vladimir Divoky, Josef T. Prchal
Blood. 2014 Jan 16; 123(3): 391–394. Prepublished online 2013 Dec 2. doi: 10.1182/blood-2013-10-534222
PMCID:
PMC3952363
AbstractArticle
14.
Transcription factor nuclear factor erythroid-2 mediates expression of the cytokine interleukin 8, a known predictor of inferior outcome in patients with myeloproliferative neoplasms
Julius Wehrle, Thalia S. Seeger, Sven Schwemmers, Dietmar Pfeifer, Alla Bulashevska, Heike L. Pahl
Haematologica. 2013 Jul; 98(7): 1073–1080. doi: 10.3324/haematol.2012.071183
PMCID:
PMC3696611
AbstractArticlePDF–1.3M
15.
A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter
Ashley O. Yocum, Laurie A. Steiner, Nancy E. Seidel, Amanda P. Cline, Emily D. Rout, Jolinta Y. Lin, Clara Wong, Lisa J. Garrett, Patrick G. Gallagher, David M. Bodine
Blood. 2012 Oct 25; 120(17): 3586–3593. Prepublished online 2012 Sep 11. doi: 10.1182/blood-2012-08-450262
PMCID:
PMC3482866
AbstractArticle
16.
AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2
Wei Wang, Sven Schwemmers, Elizabeth O. Hexner, Heike L. Pahl
Blood. 2010 Jul 15; 116(2): 254–266. Prepublished online 2010 Mar 25. doi: 10.1182/blood-2009-11-254664
PMCID:
PMC2910609
AbstractArticle
17.
In vivo footprinting of the human alpha-globin locus upstream regulatory element by guanine and adenine ligation-mediated polymerase chain reaction.
E C Strauss, N C Andrews, D R Higgs, S H Orkin
Mol Cell Biol. 1992 May; 12(5): 2135–2142. doi: 10.1128/mcb.12.5.2135
PMCID:
PMC364385
SummaryPage BrowsePDF–1.8M
18.
NFE2/miR-423-5p/TFF1 axis regulates high glucose-induced apoptosis in retinal pigment epithelial cells
Qing Xiao, Yinu Zhao, Jia Xu, Wen-Jie Li, Yu Chen, Hong-Jing Sun
BMC Mol Cell Biol. 2019; 20: 39. Published online 2019 Aug 27. doi: 10.1186/s12860-019-0223-2
PMCID:
PMC6712806
AbstractArticlePDF–1.9M
19.
The Up-Regulation of miR-199b-5p in Erythroid Differentiation Is Associated with GATA-1 and NF-E2
Yuxia Li, Hua Bai, Zhongzu Zhang, Weihua li, Lei Dong, Xueju Wei, Yanni Ma, Junwu Zhang, Jia Yu, Guotao Sun, Fang Wang
Mol Cells. 2014 Mar 31; 37(3): 213–219. Published online 2014 Mar 6. doi: 10.14348/molcells.2014.2288
PMCID:
PMC3969041
AbstractArticlePDF–656K
20.
Nuclear Factor Erythroid-derived 2 (Nfe2) Regulates JunD DNA-binding Activity via Acetylation: A NOVEL MECHANISM REGULATING TROPHOBLAST DIFFERENTIATION
Muhammed Kashif, Andrea Hellwig, Said Hashemolhosseini, Varun Kumar, Fabian Bock, Hongjie Wang, Khurrum Shahzad, Satish Ranjan, Juliane Wolter, Thati Madhusudhan, Angelika Bierhaus, Peter Nawroth, Berend Isermann
J Biol Chem. 2012 Feb 17; 287(8): 5400–5411. Published online 2011 Dec 15. doi: 10.1074/jbc.M111.289801
PMCID:
PMC3285319
AbstractArticlePDF–2.7M

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