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Items: 1 to 20 of 539

1.
Comprehensive Molecular Profiling of NPM1-Mutated Acute Myeloid Leukemia Using RNAseq Approach
Jessica Petiti, Ymera Pignochino, Aurora Schiavon, Emilia Giugliano, Enrico Berrino, Giorgia Giordano, Federico Itri, Matteo Dragani, Daniela Cilloni, Marco Lo Iacono
Int J Mol Sci. 2024 Apr; 25(7): 3631. Published online 2024 Mar 24. doi: 10.3390/ijms25073631
PMCID:
PMC11011776
ArticlePDF–785K
2.
Mutations highly specific for secondary AML are associated with poor outcomes in ELN favorable risk NPM1-mutated AML
Onyee Chan, Najla Al Ali, Hammad Tashkandi, Austin Ellis, Somedeb Ball, Justin Grenet, Caroline Hana, Yehuda Deutsch, Ling Zhang, Mohammad Hussaini, Jinming Song, Seongseok Yun, Chetasi Talati, Andrew Kuykendall, Eric Padron, Alison Walker, Gail Roboz, Pinkal Desai, David Sallman, Kendra Sweet, Rami Komrokji, Jeffrey Lancet
Blood Adv. 2024 Mar 12; 8(5): 1075–1083. Published online 2024 Jan 5. doi: 10.1182/bloodadvances.2023011173
PMCID:
PMC10907389
ArticlePDF–1.7M
3.
NPM1-Mutated Acute Myeloid Leukemia: Recent Developments and Open Questions
Sanjay S. Patel
Pathobiology. 2024 Feb; 91(1): 18–29. Published online 2023 Mar 21. doi: 10.1159/000530253
PMCID:
PMC10857804
Article
4.
Clinical outcomes associated with NPM1 mutations in patients with relapsed or refractory AML
Ghayas C. Issa, Aram Bidikian, Sangeetha Venugopal, Marina Konopleva, Courtney D. DiNardo, Tapan M. Kadia, Gautam Borthakur, Elias Jabbour, Naveen Pemmaraju, Musa Yilmaz, Nicholas J. Short, Abhishek Maiti, Koji Sasaki, Lucia Masarova, Sherry Pierce, Koichi Takahashi, Guilin Tang, Sanam Loghavi, Keyur Patel, Michael Andreeff, Kapil Bhalla, Guillermo Garcia-Manero, Farhad Ravandi, Hagop Kantarjian, Naval Daver
Blood Adv. 2023 Mar 28; 7(6): 933–942. Published online 2022 Nov 4. doi: 10.1182/bloodadvances.2022008316
PMCID:
PMC10027507
ArticlePDF–554K
5.
Positive Linear Relationship between Nucleophosmin Protein Expression and the Viral Load in HPV-Associated Oropharyngeal Squamous Cell Carcinoma: A Possible Tool for Stratification of Patients
Marco D’Agostino, Marco Di Cecco, Carla Marani, Maurizio Giovanni Vigili, Sara Sileno, Chiara Costanza Volpi, Annunziata Gloghini, Daniele Avitabile, Alessandra Magenta, Siavash Rahimi
Int J Mol Sci. 2023 Feb; 24(4): 3482. Published online 2023 Feb 9. doi: 10.3390/ijms24043482
PMCID:
PMC9967283
ArticlePDF–1.3M
6.
Targeting and Monitoring Acute Myeloid Leukaemia with Nucleophosmin-1 (NPM1) Mutation
Lynn Chin, Chantelle Ye Gwen Wong, Harinder Gill
Int J Mol Sci. 2023 Feb; 24(4): 3161. Published online 2023 Feb 5. doi: 10.3390/ijms24043161
PMCID:
PMC9958584
ArticlePDF–2.7M
7.
Insights into Network of Hot Spots of Aggregation in Nucleophosmin 1
Daniele Florio, Sara La Manna, Concetta Di Natale, Marilisa Leone, Flavia Anna Mercurio, Fabiana Napolitano, Anna Maria Malfitano, Daniela Marasco
Int J Mol Sci. 2022 Dec; 23(23): 14704. Published online 2022 Nov 25. doi: 10.3390/ijms232314704
PMCID:
PMC9736328
ArticlePDF–41M
8.
The antagonistic duality of NPM1 mutations in AML
Irum Khan, Andrei L. Gartel
Blood Adv. 2022 Jul 12; 6(13): 4028–4030. Published online 2022 Jul 11. doi: 10.1182/bloodadvances.2022007420
PMCID:
PMC9278292
ArticlePDF–684K
9.
Clinical impact of NPM1-mutant molecular persistence after chemotherapy for acute myeloid leukemia
Ing S. Tiong, Richard Dillon, Adam Ivey, James A. Kuzich, Nisha Thiagarajah, Kirsty M. Sharplin, Chung Hoow Kok, Aditya Tedjaseputra, James P. Rowland, Carolyn S. Grove, Emad Abro, Jake Shortt, Devendra K. Hiwase, Ashish Bajel, Nicola E. Potter, Matthew L. Smith, Claire J. Hemmaway, Abin Thomas, Amanda F. Gilkes, Nigel H. Russell, Andrew H. Wei
Blood Adv. 2021 Dec 14; 5(23): 5107–5111. Published online 2021 Dec 6. doi: 10.1182/bloodadvances.2021005455
Correction in:
Blood Adv. 2022 Mar 8; 6(5): 1489.
PMCID:
PMC9153038
ArticlePDF–790K
10.
Novel NPM1 exon 5 mutations and gene fusions leading to aberrant cytoplasmic nucleophosmin in AML
Maria Paola Martelli, Roberta Rossi, Alessandra Venanzi, Manja Meggendorfer, Vincenzo Maria Perriello, Giovanni Martino, Orietta Spinelli, Raffaella Ciurnelli, Emanuela Varasano, Lorenzo Brunetti, Stefano Ascani, Corinne Quadalti, Valeria Cardinali, Federica Mezzasoma, Ilaria Gionfriddo, Francesca Milano, Roberta Pacini, Alessia Tabarrini, Barbara Bigerna, Francesco Albano, Giorgina Specchia, Calogero Vetro, Francesco Di Raimondo, Ombretta Annibali, Giuseppe Avvisati, Alessandro Rambaldi, Franca Falzetti, Enrico Tiacci, Paolo Sportoletti, Torsten Haferlach, Claudia Haferlach, Brunangelo Falini
Blood. 2021 Dec 23; 138(25): 2696–2701. doi: 10.1182/blood.2021012732
PMCID:
PMC9037756
Article
11.
Flow Cytometric Immunophenotypic Alterations of Persistent Clonal Hematopoiesis in Remission Bone Marrows of Patients with NPM1-Mutated Acute Myeloid Leukemia
Sanam Loghavi, Courtney DiNardo, Ken Furudate, Koichi Takahashi, Tomoyuki Tanaka, Nicholas J. Short, Tapan Kadia, Marina Konopleva, Rashmi Kanagal-Shamanna, Noushin R. Farnoud, Sherry Pierce, Joseph D. Khoury, Jeffrey L. Jorgensen, Keyur P. Patel, Naval Daver, Musa Yilmaz, L. Jeffrey Medeiros, Hagop Kantarjian, Farhad Ravandi, Sa A. Wang
Br J Haematol. Author manuscript; available in PMC 2022 Mar 24.
Published in final edited form as: Br J Haematol. 2021 Mar; 192(6): 1054–1063. Published online 2021 Feb 22. doi: 10.1111/bjh.17347
PMCID:
PMC8944196
ArticlePDF–1.0M
12.
Deep learning detects acute myeloid leukemia and predicts NPM1 mutation status from bone marrow smears
Jan-Niklas Eckardt, Jan Moritz Middeke, Sebastian Riechert, Tim Schmittmann, Anas Shekh Sulaiman, Michael Kramer, Katja Sockel, Frank Kroschinsky, Ulrich Schuler, Johannes Schetelig, Christoph Röllig, Christian Thiede, Karsten Wendt, Martin Bornhäuser
Leukemia. 2022; 36(1): 111–118. Published online 2021 Sep 8. doi: 10.1038/s41375-021-01408-w
PMCID:
PMC8727290
ArticlePDF–1.7M
13.
Molecular study of Nucleophosmin 1(NPM1) gene in acute myeloid leukemia in Kurdish population
Galawezh Obaid Othman, Nawsherwan Sadiq Mohammad, Chiman Hameed Saeed
Afr Health Sci. 2021 Jun; 21(2): 687–692. doi: 10.4314/ahs.v21i2.26
PMCID:
PMC8568245
ArticlePDF–356K
14.
Integrated genomic-metabolic classification of acute myeloid leukemia defines a subgroup with NPM1 and cohesin/DNA damage mutations
Giorgia Simonetti, Carlo Mengucci, Antonella Padella, Eugenio Fonzi, Gianfranco Picone, Claudio Delpino, Jacopo Nanni, Rossella De Tommaso, Eugenia Franchini, Cristina Papayannidis, Giovanni Marconi, Martina Pazzaglia, Margherita Perricone, Emanuela Scarpi, Maria Chiara Fontana, Samantha Bruno, Michela Tebaldi, Anna Ferrari, Maria Teresa Bochicchio, Andrea Ghelli Luserna Di Rorà, Martina Ghetti, Roberta Napolitano, Annalisa Astolfi, Carmen Baldazzi, Viviana Guadagnuolo, Emanuela Ottaviani, Ilaria Iacobucci, Michele Cavo, Gastone Castellani, Torsten Haferlach, Daniel Remondini, Francesco Capozzi, Giovanni Martinelli
Leukemia. 2021; 35(10): 2813–2826. Published online 2021 Jun 30. doi: 10.1038/s41375-021-01318-x
PMCID:
PMC8478658
ArticlePDF–4.3M
15.
Significance of NPM1 Gene Mutations in AML
Andrew Hindley, Mark Alexander Catherwood, Mary Frances McMullin, Ken I. Mills
Int J Mol Sci. 2021 Sep; 22(18): 10040. Published online 2021 Sep 17. doi: 10.3390/ijms221810040
PMCID:
PMC8467861
ArticlePDF–1.8M
16.
Chromosomal Abnormalities and Prognosis in NPM1-Mutated Acute Myeloid Leukemia: A Pooled Analysis of Individual Patient Data From Nine International Cohorts
Linus Angenendt, Christoph Röllig, Pau Montesinos, David Martínez-Cuadrón, Eva Barragan, Raimundo García, Carmen Botella, Pilar Martínez, Farhad Ravandi, Tapan Kadia, Hagop M. Kantarjian, Jorge Cortes, Gunnar Juliusson, Vladimir Lazarevic, Martin Höglund, Sören Lehmann, Christian Recher, Arnaud Pigneux, Sarah Bertoli, Pierre-Yves Dumas, Hervé Dombret, Claude Preudhomme, Jean-Baptiste Micol, Christine Terré, Zdeněk Ráčil, Jan Novák, Pavel Žák, Andrew H. Wei, Ing S. Tiong, Meaghan Wall, Elihu Estey, Carole Shaw, Rita Exeler, Lisa Wagenführ, Friedrich Stölzel, Christian Thiede, Matthias Stelljes, Georg Lenz, Jan-Henrik Mikesch, Hubert Serve, Gerhard Ehninger, Wolfgang E. Berdel, Michael Kramer, Utz Krug, Christoph Schliemann
J Clin Oncol. 2019 Oct 10; 37(29): 2632–2642. Published online 2019 Aug 20. doi: 10.1200/JCO.19.00416
PMCID:
PMC8462529
ArticlePDF–969K
17.
Radar plots facilitate differential diagnosis of acute promyelocytic leukemia and NPM1+ acute myeloid leukemia by flow cytometry
Monali Gupta, Katayoon Jafari, Amr Rajab, Cuihong Wei, Joanna Mazur, Anne Tierens, Elizabeth Hyjek, Rumina Musani, Anna Porwit
Cytometry B Clin Cytom. 2021 Jul; 100(4): 409–420. Published online 2020 Dec 10. doi: 10.1002/cyto.b.21979
PMCID:
PMC8359362
ArticlePDF–5.2M
18.
The correlation of next-generation sequencing-based genotypic profiles with clinicopathologic characteristics in NPM1-mutated acute myeloid leukemia
Biao Wang, Bin Yang, Wei Wu, Xuan Liu, Haiqian Li
BMC Cancer. 2021; 21: 788. Published online 2021 Jul 8. doi: 10.1186/s12885-021-08455-7
PMCID:
PMC8268444
ArticlePDF–1.5M
19.
A novel leukemic route of mutant NPM1 through nuclear import of the overexpressed long noncoding RNA LONA
Morgane Gourvest, Etienne De Clara, Hsin-Chieh Wu, Christian Touriol, Fabienne Meggetto, Hugues De Thé, Stéphane Pyronnet, Pierre Brousset, Marina Bousquet
Leukemia. 2021; 35(10): 2784–2798. Published online 2021 Jun 15. doi: 10.1038/s41375-021-01307-0
PMCID:
PMC8205207
ArticlePDF–1.6M
20.
Two Novel Mutations of the NPM1 Gene in Syrian Adult Patients with Acute Myeloid Leukemia and Normal Karyotype
Ismael F. Alarbeed, Abdulsamad Wafa, Faten Moassass, Balssel Al-Halabi, Walid Alachkar, Imad Aboukhamis
Asian Pac J Cancer Prev. 2021 Jan; 22(1): 227–232. doi: 10.31557/APJCP.2021.22.1.227
PMCID:
PMC8184179
ArticlePDF–448K

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