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Select item 97384371.

SERPINB2, an Early Responsive Gene to Epigallocatechin Gallate, Inhibits Migration and Promotes Apoptosis in Esophageal Cancer Cells

Zikai Chen, Yifu Wei, Yuzhong Zheng, Hui Zhu, Qian Teng, Xianglan Lin, Fengnian Wu, Fei Zhou

Cells. 2022 Dec; 11(23): 3852. Published online 2022 Nov 30. doi: 10.3390/cells11233852

PMCID:: PMC9738437

Article PDF–8.3M

Select item 89979072.

A Novel Role for Plasminogen Activator Inhibitor Type-2 as a Hypochlorite-Resistant Serine Protease Inhibitor and Holdase Chaperone

Jordan H. Cater, Noralyn B. Mañucat-Tan, Demi K. Georgiou, Guomao Zhao, Irina A. Buhimschi, Amy R. Wyatt, Marie Ranson

Cells. 2022 Apr; 11(7): 1152. Published online 2022 Mar 29. doi: 10.3390/cells11071152

PMCID:: PMC8997907

Article PDF–4.0M

Select item 79216373.

HKB99, an allosteric inhibitor of phosphoglycerate mutase 1, suppresses invasive pseudopodia formation and upregulates plasminogen activator inhibitor-2 in erlotinib-resistant non-small cell lung cancer cells

Qian Liang, Wei-ming Gu, Ke Huang, Ming-yu Luo, Jing-hua Zou, Guang-lei Zhuang, Hui-min Lei, Hong-zhuan Chen, Liang Zhu, Lu Zhou, Ying Shen

Acta Pharmacol Sin. 2021 Jan; 42(1): 115–119. Published online 2020 May 13. doi: 10.1038/s41401-020-0399-1

PMCID:: PMC7921637

Article PDF–1.2M

Select item 77914064.

Deficiency of Plasminogen Activator Inhibitor-2 Results in Accelerated Tumor Growth

Randal J. Westrick, Lisa Payne Røjkjær, Angela Y. Yang, Michael H. Roh, Amy E. Siebert, David Ginsburg

J Thromb Haemost. Author manuscript; available in PMC 2021 Nov 1.

Published in final edited form as: J Thromb Haemost. 2020 Nov; 18(11): 2968–2975. Published online 2020 Oct 1. doi: 10.1111/jth.15054

PMCID:: PMC7791406

Article PDF–1.3M

Select item 60104325.

SERPINB2 is a novel indicator of stem cell toxicity

Na-Hee Lee, Ara Cho, Se-Ra Park, Jin Woo Lee, Park Sung Taek, Chan Hum Park, Yoon-Hyeong Choi, Soyi Lim, Min-Kwan Baek, Dong Young Kim, Mirim Jin, Hwa-Yong Lee, In-Sun Hong

Cell Death Dis. 2018 Jul; 9(7): 724. Published online 2018 Jun 20. doi: 10.1038/s41419-018-0748-x

PMCID:: PMC6010432

Article PDF–2.3M

Select item 55898086.

SERPINB2 is a novel TGFβ-responsive lineage fate determinant of human bone marrow stromal cells

Mona Elsafadi, Muthurangan Manikandan, Muhammad Atteya, Raed Abu Dawud, Sami Almalki, Zahid Ali Kaimkhani, Abdullah Aldahmash, Nehad M. Alajez, Musaad Alfayez, Moustapha Kassem, Amer Mahmood

Sci Rep. 2017; 7: 10797. Published online 2017 Sep 7. doi: 10.1038/s41598-017-10983-x

PMCID:: PMC5589808

Article PDF–6.7M

Select item 55358067.

SERPINB2 is regulated by dynamic interactions with pause-release proteins and enhancer RNAs

Lihua Shi, Li Song, Kelly Maurer, Zhe Zhang, Kathleen E. Sullivan

Mol Immunol. Author manuscript; available in PMC 2018 Aug 1.

Published in final edited form as: Mol Immunol. 2017 Aug; 88: 20–31. Published online 2017 Jun 1. doi: 10.1016/j.molimm.2017.05.005

PMCID:: PMC5535806

Article PDF–1.4M

Select item 54648268.

microRNA-200c/141 upregulates SerpinB2 to promote breast cancer cell metastasis and reduce patient survival

Tiefeng Jin, Hoe Suk Kim, Sul Ki Choi, Eun Hye Hwang, Jisu Woo, Han Suk Ryu, Kwangsoo Kim, Aree Moon, Woo Kyung Moon

Oncotarget. 2017 May 16; 8(20): 32769–32782. Published online 2017 Feb 24. doi: 10.18632/oncotarget.15680

PMCID:: PMC5464826

Article PDF–4.8M

Select item 49976079.

Down-regulation of SerpinB2 is associated with gefitinib resistance in non-small cell lung cancer and enhances invadopodia-like structure protrusions

Song Yi Bae, Hyen Joo Park, Ji-Young Hong, Hye-Jung Lee, Sang Kook Lee

Sci Rep. 2016; 6: 32258. Published online 2016 Aug 25. doi: 10.1038/srep32258

PMCID:: PMC4997607

Article PDF–2.5M

Select item 464757310.

Variant of PAI-2 gene is associated with coronary artery disease and recurrent coronary event risk in Chinese Han population

Xia Li, Jun-Yi Luo, Lei Zhang, Yi-Ning Yang, Xiang Xie, Fen Liu, Bang-Dang Chen, Yi-Tong Ma

Lipids Health Dis. 2015; 14: 148. Published online 2015 Nov 16. doi: 10.1186/s12944-015-0150-y

PMCID:: PMC4647573

Article PDF–490K

Select item 332299411.

Regulation of the Human Plasminogen Activator Inhibitor Type 2 Gene: COOPERATION OF AN UPSTREAM SILENCER AND TRANSACTIVATOR

Brett Stringer, Ekemini A. Udofa, Toni M. Antalis

J Biol Chem. 2012 Mar 23; 287(13): 10579–10589. Published online 2012 Feb 9. doi: 10.1074/jbc.M111.318758

PMCID:: PMC3322994

Article PDF–3.5M

Select item 218863012.

Human monocyte Arg-Serpin cDNA. Sequence, chromosomal assignment, and homology to plasminogen activator-inhibitor

J Exp Med. 1987 Jul 1; 166(1): 77–94. doi: 10.1084/jem.166.1.77

PMCID:: PMC2188630

Summary PDF–1.3M

Select item 36814413.

Plasminogen activator inhibitor 2: regulation of gene transcription during phorbol ester-mediated differentiation of U-937 human histiocytic lymphoma cells.

W D Schleuning, R L Medcalf, C Hession, R Rothenbühler, A Shaw, E K Kruithof

Mol Cell Biol. 1987 Dec; 7(12): 4564–4567. doi: 10.1128/mcb.7.12.4564

PMCID:: PMC368144

Summary Page Browse PDF–716K

Select item 27968514.

Cloning and expression of a cDNA coding for a human monocyte-derived plasminogen activator inhibitor.

T M Antalis, M A Clark, T Barnes, P R Lehrbach, P L Devine, G Schevzov, N H Goss, R W Stephens, P Tolstoshev

Proc Natl Acad Sci U S A. 1988 Feb; 85(4): 985–989. doi: 10.1073/pnas.85.4.985

PMCID:: PMC279685

Summary Page Browse PDF–1.3M

Select item 15447015.

A redox-sensitive loop regulates plasminogen activator inhibitor type 2 (PAI-2) polymerization

Malgorzata Wilczynska, Sergei Lobov, Per-Ingvar Ohlsson, Tor Ny

EMBO J. 2003 Apr 15; 22(8): 1753–1761. doi: 10.1093/emboj/cdg178

PMCID:: PMC154470

Article PDF–305K

Select item 10424316.

Picornavirus Receptor Down-Regulation by Plasminogen Activator Inhibitor Type 2

D. R. Shafren, J. Gardner, V. H. Mann, T. M. Antalis, A. Suhrbier

J Virol. 1999 Sep; 73(9): 7193–7198. doi: 10.1128/jvi.73.9.7193-7198.1999

PMCID:: PMC104243

Article PDF–1.2M

Select item 814084117.

HMSC-Derived Exosome Inhibited Th2 Cell Differentiation via Regulating miR-146a-5p/SERPINB2 Pathway

Jing Zhou, Yi Lu, Wei Wu, Yunhai Feng

J Immunol Res. 2021; 2021: 6696525. Published online 2021 May 14. doi: 10.1155/2021/6696525

PMCID:: PMC8140841

Article PDF–2.1M

Select item 577315418.

The microRNA-15a-PAI-2 axis in cholangiocarcinoma-associated fibroblasts promotes migration of cancer cells

Penkhae Utaijaratrasmi, Kulthida Vaeteewoottacharn, Takaaki Tsunematsu, Pranisa Jamjantra, Sopit Wongkham, Chawalit Pairojkul, Narong Khuntikeo, Naozumi Ishimaru, Yongyut Sirivatanauksorn, Ananya Pongpaibul, Peti Thuwajit, Chanitra Thuwajit, Yasusei Kudo

Mol Cancer. 2018; 17: 10. Published online 2018 Jan 18. doi: 10.1186/s12943-018-0760-x

PMCID:: PMC5773154

Article PDF–4.2M

Select item 553760619.

SerpinB2 regulates stromal remodelling and local invasion in pancreatic cancer

N L E Harris, C Vennin, J R W Conway, K L Vine, M Pinese, M J Cowley, R F Shearer, M C Lucas, D Herrmann, A H Allam, M Pajic, J P Morton, Australian Pancreatic Cancer Genome Initiative, A V Biankin, M Ranson, P Timpson, D N Saunders

Oncogene. 2017 Jul 27; 36(30): 4288–4298. Published online 2017 Mar 27. doi: 10.1038/onc.2017.63

PMCID:: PMC5537606

Article PDF–2.9M

Select item 447091720.

SerpinB2 (PAI-2) Modulates Proteostasis via Binding Misfolded Proteins and Promotion of Cytoprotective Inclusion Formation

Jodi A. Lee, Justin J. Yerbury, Natalie Farrawell, Robert F. Shearer, Patrick Constantinescu, Danny M. Hatters, Wayne A. Schroder, Andreas Suhrbier, Mark R. Wilson, Darren N. Saunders, Marie Ranson

PLoS One. 2015; 10(6): e0130136. Published online 2015 Jun 17. doi: 10.1371/journal.pone.0130136