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Items: 1 to 20 of 32

1.
Heparin activation of protein Z-dependent protease inhibitor (ZPI) allosterically blocks protein Z activation through an extended heparin-binding site
Xin Huang, Richard Swanson, Steven T. Olson
J Biol Chem. 2022 Jun; 298(6): 102022. Published online 2022 May 10. doi: 10.1016/j.jbc.2022.102022
PMCID:
PMC9190012
AbstractArticlePDF–2.0M
2.
Protein Z-dependent protease inhibitor (ZPI) is a physiologically significant inhibitor of prothrombinase function
Xin Huang, Richard Swanson, Heather K. Kroh, Paul E. Bock
J Biol Chem. 2019 May 10; 294(19): 7644–7657. Published online 2019 Mar 27. doi: 10.1074/jbc.RA118.006787
PMCID:
PMC6514612
AbstractArticlePDF–2.3M
3.
Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis
Marcin M. Gorski, Luca A. Lotta, Emanuela Pappalardo, Hugoline G. de Haan, Serena M. Passamonti, Astrid van Hylckama Vlieg, Ida Martinelli, Flora Peyvandi
PLoS One. 2016; 11(3): e0151347. Published online 2016 Mar 16. doi: 10.1371/journal.pone.0151347
PMCID:
PMC4794167
AbstractArticlePDF–263K
4.
Characterization of the heparin-binding site of protein Z-dependent protease inhibitor
Likui Yang, Qiulan Ding, Xin Huang, Steven T. Olson, Alireza R. Rezaie
Biochemistry. Author manuscript; available in PMC 2013 May 15.
Published in final edited form as: Biochemistry. 2012 May 15; 51(19): 4078–4085. Published online 2012 May 2. doi: 10.1021/bi300353c
PMCID:
PMC3352997
AbstractArticlePDF–933K
5.
Association of the R67X and W303X non-sense polymorphisms in the protein Z-dependent protease inhibitor gene with idiopathic recurrent miscarriage
F.S. AlShaikh, R.R. Finan, A.W. Almawi, F.E. Mustafa, W.Y. Almawi
Mol Hum Reprod. 2012 Mar; 18(3): 156–160. Published online 2011 Oct 27. doi: 10.1093/molehr/gar069
PMCID:
PMC3292391
AbstractArticlePDF–149K
6.
Heparin Is a Major Activator of the Anticoagulant Serpin, Protein Z-dependent Protease Inhibitor
Xin Huang, Alireza R. Rezaie, George J. Broze, Jr, Steven T. Olson
J Biol Chem. 2011 Mar 18; 286(11): 8740–8751. Published online 2011 Jan 10. doi: 10.1074/jbc.M110.188375
PMCID:
PMC3058988
AbstractArticlePDF–1.6M
7.
A nonsense polymorphism in the protein Z-dependent protease inhibitor increases the risk for venous thrombosis
Javier Corral, Rocio González-Conejero, Jose Manuel Soria, Jose Ramón González-Porras, Elena Pérez-Ceballos, Ramón Lecumberri, Vanessa Roldán, Juan Carlos Souto, Antonia Miñano, David Hernández-Espinosa, Ignacio Alberca, Jordi Fontcuberta, Vicente Vicente
Blood. 2006 Jul 1; 108(1): 177–183. Prepublished online 2006 Mar 9. doi: 10.1182/blood-2005-08-3249
PMCID:
PMC1895831
AbstractArticle
8.
Thermodynamic and Kinetic Characterization of the Protein Z-dependent Protease Inhibitor (ZPI)-Protein Z Interaction Reveals an Unexpected Role for ZPI Lys-239
Xin Huang, Jian Zhou, Aiwu Zhou, Steven T. Olson
J Biol Chem. 2015 Apr 10; 290(15): 9906–9918. Published online 2015 Feb 20. doi: 10.1074/jbc.M114.633479
PMCID:
PMC4392287
AbstractArticlePDF–1.3M
9.
Characterization of the Protein Z-dependent Protease Inhibitor Interactive-sites of Protein Z
Shabir H Qureshi, Qiuya Lu, Chandrashekhara Manithody, Likui Yang, Alireza R. Rezaie
Biochim Biophys Acta. Author manuscript; available in PMC 2015 Sep 1.
Published in final edited form as: Biochim Biophys Acta. 2014 Sep; 1844(9): 1631–1637. Published online 2014 Jun 21. doi: 10.1016/j.bbapap.2014.06.011
PMCID:
PMC4118583
AbstractArticlePDF–899K
10.
Protein Z and protein Z-dependent protease inhibitor and renal tubules
George J. Broze, Jr., Yizheng Tu
Thromb Haemost. Author manuscript; available in PMC 2011 Feb 1.
Published in final edited form as: Thromb Haemost. 2010 Feb 1; 103(2): 473–474. Published online 2009 Dec 18. doi: 10.1160/TH09-02-0131
PMCID:
PMC2879324
ArticlePDF–822K
11.
A computational modeling and molecular dynamics study of the Michaelis complex of human protein Z-dependent protease inhibitor (ZPI) and factor Xa (FXa)
Vasudevan Chandrasekaran, Chang Jun Lee, Ping Lin, Robert E. Duke, Lee G. Pedersen
J Mol Model. Author manuscript; available in PMC 2009 Aug 10.
Published in final edited form as: J Mol Model. 2009 Aug; 15(8): 897–911. Published online 2009 Jan 27. doi: 10.1007/s00894-008-0444-3
PMCID:
PMC2723763
AbstractArticlePDF–5.4M
12.
Identification of Factor Xa Residues Critical for Interaction with Protein Z-dependent Protease Inhibitor: Both Active-site and Exosite Interactions Are Required for Inhibition
Alireza R. Rezaie, Chandrashekhara Manithody, Likui Yang
J Biol Chem. Author manuscript; available in PMC 2005 Oct 26.
Published in final edited form as: J Biol Chem. 2005 Sep 23; 280(38): 32722–32728. Published online 2005 Aug 3. doi: 10.1074/jbc.M505517200
PMCID:
PMC1266280
AbstractArticlePDF–348K
13.
Isolation of a protein Z-dependent plasma protease inhibitor
Xin Han, Ryan Fiehler, George J. Broze, Jr.
Proc Natl Acad Sci U S A. 1998 Aug 4; 95(16): 9250–9255. doi: 10.1073/pnas.95.16.9250
PMCID:
PMC21324
AbstractArticlePDF–222K
14.
Lipid oxidation inactivates the anticoagulant function of protein Z-dependent protease inhibitor (ZPI)
Xin Huang, Baoxin Liu, Yidong Wei, Ryan Beyea, Han Yan, Steven T. Olson
J Biol Chem. 2017 Sep 1; 292(35): 14625–14635. Published online 2017 Jul 17. doi: 10.1074/jbc.M117.793901
PMCID:
PMC5582853
AbstractArticlePDF–2.2M
15.
Protein Z/protein Z-dependent protease inhibitor system in loco in human gastric cancer
Ewa Sierko, Marek Z. Wojtukiewicz, Lech Zimnoch, Piotr Tokajuk, Krystyna Ostrowska-Cichocka, Walter Kisiel
Ann Hematol. 2014; 93(5): 779–784. Published online 2013 Oct 26. doi: 10.1007/s00277-013-1941-8
PMCID:
PMC3976510
AbstractArticlePDF–1.0M
16.
Structural basis for catalytic activation of protein Z–dependent protease inhibitor (ZPI) by protein Z
Xin Huang, Yahui Yan, Yizheng Tu, Jeffrey Gatti, George J. Broze, Jr, Aiwu Zhou, Steven T. Olson
Blood. 2012 Aug 23; 120(8): 1726–1733. Prepublished online 2012 Jul 11. doi: 10.1182/blood-2012-03-419598
PMCID:
PMC3429311
AbstractArticle
17.
Basis for the Specificity and Activation of the Serpin Protein Z-dependent Proteinase Inhibitor (ZPI) as an Inhibitor of Membrane-associated Factor Xa
Xin Huang, Alexey Dementiev, Steven T. Olson, Peter G. W. Gettins
J Biol Chem. 2010 Jun 25; 285(26): 20399–20409. Published online 2010 Apr 28. doi: 10.1074/jbc.M110.112748
PMCID:
PMC2888451
AbstractArticlePDF–2.4M
18.
Kinetic Characterization of the Protein Z-dependent Protease Inhibitor Reaction with Blood Coagulation Factor Xa
Xin Huang, Richard Swanson, George J. Broze, Jr., Steven T. Olson
J Biol Chem. 2008 Oct 31; 283(44): 29770–29783. doi: 10.1074/jbc.M805214200
PMCID:
PMC2573075
AbstractArticlePDF–781K
19.
Prothrombotic phenotype of protein Z deficiency
Zheng-Feng Yin, Zhong-Fu Huang, Jisong Cui, Ryan Fiehler, Nina Lasky, David Ginsburg, George J. Broze, Jr.
Proc Natl Acad Sci U S A. 2000 Jun 6; 97(12): 6734–6738. Published online 2000 May 30. doi: 10.1073/pnas.120081897
PMCID:
PMC18721
AbstractArticlePDF–607K
20.
Residues of the 39-Loop Restrict the Plasma Inhibitor Specificity of Factor IXa
Likui Yang, Alireza R. Rezaie
J Biol Chem. 2013 May 3; 288(18): 12692–12698. Published online 2013 Mar 25. doi: 10.1074/jbc.M113.459347
PMCID:
PMC3642315
AbstractArticlePDF–703K

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