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Select item 66679241.

Knockdown of Nemo-like kinase promotes metastasis in non-small-cell lung cancer

Cui Shi, Liqin Xu, Zhiyuan Tang, Weishuai Zhang, Yulin Wei, Jun Ni, Shuwen Zhang, Jian Feng

Oncol Rep. 2019 Sep; 42(3): 1090–1100. Published online 2019 Jul 9. doi: 10.3892/or.2019.7226

PMCID:: PMC6667924

Abstract Article PDF–1.0M

Select item 46206022.

NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin

Dong Suwei, Zeng Liang, Liu Zhimin, Li Ruilei, Zou Yingying, Li Zhen, Ge Chunlei, Lai Zhangchao, Xue Yuanbo, Yang Jinyan, Li Gaofeng, Song Xin

J Hematol Oncol. 2015; 8: 120. Published online 2015 Oct 26. doi: 10.1186/s13045-015-0203-8

Correction in:: J Hematol Oncol. 2016; 9: 11.

PMCID:: PMC4620602

Abstract Article PDF–2.0M

Select item 45817643.

Lentivirus-delivered nemo-like kinase small interfering RNA inhibits laryngeal cancer cell proliferation in vitro

JUN TAI, YUANSHENG RAO, JUGAO FANG, ZHIGANG HUANG, ZHENKUN YU, XIAOHONG CHEN, WEIGUO ZHOU, XIAO XIAO, TING LONG, YANG HAN, QIAOYIN LIU, AIDONG LI, XIN NI

Mol Med Rep. 2015 Oct; 12(4): 5619–5624. Published online 2015 Aug 6. doi: 10.3892/mmr.2015.4189

PMCID:: PMC4581764

Abstract Article PDF–1.0M

Select item 45280264.

Upregulation of nemo-like kinase is an independent prognostic factor in colorectal cancer

Wei Zhang, Jian He, Yan Du, Xian-Hua Gao, Yan Liu, Qi-Zhi Liu, Wen-Jun Chang, Guang-Wen Cao, Chuan-Gang Fu

World J Gastroenterol. 2015 Aug 7; 21(29): 8836–8847. Published online 2015 Aug 7. doi: 10.3748/wjg.v21.i29.8836

PMCID:: PMC4528026

Abstract Article PDF–2.0M

Select item 37534145.

Lentivirus-based RNA Silencing of Nemo-like Kinase (NLK) Inhibits the CAL 27 Human Adenosquamos Carcinoma Cells Proliferation and Blocks G0/G1 Phase to S Phase

Bin Zhang, Ke Yi Li, Hai Ying Chen, Shao Dong Pan, Shuang Feng Chen, Wei Feng Zhang, Chun Peng Xia, Li Cheng Jiang, Xian Bin Liu, Feng Jun Zhao, Dao Ying Yuan, Le Xin Wang, Ya Ping Wu, Shu Wei Liu

Int J Med Sci. 2013; 10(10): 1301–1306. Published online 2013 Aug 8. doi: 10.7150/ijms.6607

PMCID:: PMC3753414

Abstract Article PDF–535K

Select item 32976836.

Common variation in Nemo-like kinase (NLK) is associated with risk of ovarian cancer

Kristen N. Stevens, Linda E. Kelemen, Xianshu Wang, Brooke L. Fridley, Robert A. Vierkant, Zachary Fredericksen, Sebastian M. Armasu, Ya-Yu Tsai, Andrew Berchuck, Steven A. Narod, Catherine M. Phelan, Rebecca Sutphen, Michael J. Birrer, Joellen M. Schildkraut, Thomas A. Sellers, Ellen L. Goode, Ovarian Cancer Association Consortium, Fergus J. Couch

Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2013 Mar 1.

Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2012 Mar; 21(3): 523–528. Published online 2012 Jan 17. doi: 10.1158/1055-9965.EPI-11-0797

PMCID:: PMC3297683

Abstract Article PDF–374K

Select item 30209217.

Homodimerization of Nemo-like kinase is essential for activation and nuclear localization

Shizuka Ishitani, Kenji Inaba, Kunihiro Matsumoto, Tohru Ishitani

Mol Biol Cell. 2011 Jan 15; 22(2): 266–277. doi: 10.1091/mbc.E10-07-0605

PMCID:: PMC3020921

Abstract Article PDF–10M

Select item 104252138.

Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43–related neurodegeneration

Leon Tejwani, Youngseob Jung, Hiroshi Kokubu, Sowmithra Sowmithra, Luhan Ni, Changwoo Lee, Benjamin Sanders, Paul J. Lee, Yangfei Xiang, Kimberly Luttik, Armand Soriano, Jennifer Yoon, Junhyun Park, Hannah H. Ro, Hyoungseok Ju, Clara Liao, Sofia Massaro Tieze, Frank Rigo, Paymaan Jafar-Nejad, Janghoo Lim

J Clin Invest. 2023 Aug 15; 133(16): e138207. Published online 2023 Aug 15. doi: 10.1172/JCI138207

PMCID:: PMC10425213

Abstract Article PDF–19M

Select item 48152679.

Nemo-like kinase as a negative regulator of nuclear receptor Nurr1 gene transcription in prostate cancer

Jian Wang, Zhi-Hong Yang, Hua Chen, Hua-Hui Li, Li-Yong Chen, Zhu Zhu, Ying Zou, Cong-Cong Ding, Jing Yang, Zhi-Wei He

BMC Cancer. 2016; 16: 257. Published online 2016 Mar 31. doi: 10.1186/s12885-016-2291-4

PMCID:: PMC4815267

Abstract Article PDF–2.3M

Select item 471363410.

Expression of Nemo-like kinase was increased and negatively correlated with the expression of TCF4 in lung cancers

Xiu-Wei Zhang, Song-Yan Chen, Dong-Wei Xue, Hui-Hui Xu, Lian-He Yang, Hong-Tao Xu, En-Hua Wang

Int J Clin Exp Pathol. 2015; 8(11): 15086–15092. Published online 2015 Nov 1.

PMCID:: PMC4713634

Abstract Article PDF–684K

Select item 401599011.

Association of Nuclear-Localized Nemo-Like Kinase with Heat-Shock Protein 27 Inhibits Apoptosis in Human Breast Cancer Cells

Gina Shaw-Hallgren, Katarzyna Chmielarska Masoumi, Reihaneh Zarrizi, Ulf Hellman, Per Karlsson, Khalil Helou, Ramin Massoumi

PLoS One. 2014; 9(5): e96506. Published online 2014 May 9. doi: 10.1371/journal.pone.0096506

PMCID:: PMC4015990

Abstract Article PDF–1.9M

Select item 372054312.

Nemo-Like Kinase Associated with Proliferation and Apoptosis by c-Myb Degradation in Breast Cancer

Yeqing Huang, Ying Jiang, Weiqi Lu, Yong Zhang

PLoS One. 2013; 8(7): e69148. Published online 2013 Jul 23. doi: 10.1371/journal.pone.0069148

PMCID:: PMC3720543

Abstract Article PDF–3.7M

Select item 363552213.

miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase

Kun Wang, Xuan Wang, Jian Zou, Anling Zhang, Yingfeng Wan, Peiyu Pu, Zhengfei Song, Cong Qian, Yili Chen, Shuxu Yang, Yirong Wang

Neuro Oncol. 2013 May; 15(5): 578–588. Published online 2013 Feb 14. doi: 10.1093/neuonc/not004

Correction in:: Neuro Oncol. 2013 Jul; 15(7): 970.

PMCID:: PMC3635522

Abstract Article PDF–808K

Select item 290818014.

Nemo-Like Kinase Induces Apoptosis and Inhibits Androgen Receptor Signaling in Prostate Cancer Cells

Katayoon H. Emami, Lisha G. Brown, Tiffany E.M. Pitts, Xizhang Sun, Robert L. Vessella, Eva Corey

Prostate. Author manuscript; available in PMC 2010 Oct 1.

Published in final edited form as: Prostate. 2009 Oct 1; 69(14): 1481–1492. doi: 10.1002/pros.20998

PMCID:: PMC2908180

Abstract Article PDF–3.4M

Select item 918136015.

The ubiquitin specific protease 4 (USP4) is a new player in the Wnt signalling pathway

Bin Zhao, Claudia Schlesiger, Maria G. Masucci, Kristina Lindsten

J Cell Mol Med. 2009 Aug; 13(8b): 1886–1895. Published online 2009 Nov 26. doi: 10.1111/j.1582-4934.2008.00682.x

PMCID:: PMC9181360

Abstract Article PDF–947K

Select item 716055616.

NLK interacts with 14-3-3ζ to restore the expression of E-cadherin

Jie Chen, Qingfeng Lin, Tingting Ni, Jiyi Zhao, Feng Lin, Xiangdong Lu, Ye Lv, Shujuan Ren, Zhili Liu, Ting Zhang, Shuyan He, Dong Shen, Weidong Mao

Oncol Rep. 2020 Jun; 43(6): 1845–1852. Published online 2020 Mar 20. doi: 10.3892/or.2020.7557

PMCID:: PMC7160556

Abstract Article PDF–1.1M

Select item 415869017.

Nemo-like kinase is critical for p53 stabilization and function in response to DNA damage

H-H Zhang, S-Z Li, Z-Y Zhang, X-M Hu, P-N Hou, L Gao, R-L Du, X-D Zhang

Cell Death Differ. 2014 Oct; 21(10): 1656–1663. Published online 2014 Jun 13. doi: 10.1038/cdd.2014.78

PMCID:: PMC4158690

Abstract Article PDF–1.3M

Select item 1863918.

Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus

Barbara K. Brott, Benjamin A. Pinsky, Raymond L. Erikson

Proc Natl Acad Sci U S A. 1998 Feb 3; 95(3): 963–968. doi: 10.1073/pnas.95.3.963

PMCID:: PMC18639

Abstract Article PDF–258K

Select item 664220519.

Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response

Shang-Ze Li, Qi-Peng Shu, Yang Song, Hui-Hui Zhang, Yi Liu, Bing-Xue Jin, Tian-Zi Liuyu, Chao Li, Xi-Chen Huang, Run-Lei Du, Wei Song, Bo Zhong, Xiao-Dong Zhang

Nat Commun. 2019; 10: 3233. Published online 2019 Jul 19. doi: 10.1038/s41467-019-11258-x

PMCID:: PMC6642205

Abstract Article PDF–2.9M

Select item 496838020.

Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34⁺ cells

Kshama Gupta, Inna Kuznetsova, Olga Klimenkova, Maksim Klimiankou, Johann Meyer, Malcolm A. S. Moore, Cornelia Zeidler, Karl Welte, Julia Skokowa

Blood. 2014 Apr 17; 123(16): 2550–2561. Prepublished online 2014 Jan 6. doi: 10.1182/blood-2012-09-456889

PMCID:: PMC4968380

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