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Select item 69452421.

Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer

Bo Chen, Shuhong Huang, Thomas R. Pisanic, II, Alejandro Stark, Yong Tao, Bei Cheng, Yue Li, Yunyan Wei, Weihong Zhao, Tza-Huei Wang, Jianqing Wu

EBioMedicine. 2019 Nov; 49: 118–132. Published online 2019 Nov 6. doi: 10.1016/j.ebiom.2019.10.040

PMCID:: PMC6945242

Article PDF–5.0M

Select item 46549352.

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

Yu‐Chiang Lai, Chandana Kondapalli, Ronny Lehneck, James B Procter, Brian D Dill, Helen I Woodroof, Robert Gourlay, Mark Peggie, Thomas J Macartney, Olga Corti, Jean‐Christophe Corvol, David G Campbell, Aymelt Itzen, Matthias Trost, Miratul MK Muqit

EMBO J. 2015 Nov 12; 34(22): 2840–2861. Published online 2015 Oct 16. doi: 10.15252/embj.201591593

PMCID:: PMC4654935

Article PDF–2.1M

Select item 1248883.

A Rab8-specific GDP/GTP Exchange Factor Is Involved in Actin Remodeling and Polarized Membrane Transport

Katarina Hattula, Johanna Furuhjelm, Airi Arffman, Johan Peränen

Mol Biol Cell. 2002 Sep; 13(9): 3268–3280. doi: 10.1091/mbc.E02-03-0143

PMCID:: PMC124888

Article PDF–1.0M

Select item 71998554.

GRAF2, WDR44, and MICAL1 mediate Rab8/10/11–dependent export of E-cadherin, MMP14, and CFTR ΔF508

Safa Lucken-Ardjomande Häsler, Yvonne Vallis, Mathias Pasche, Harvey T. McMahon

J Cell Biol. 2020 May 4; 219(5): e201811014. Published online 2020 Apr 28. doi: 10.1083/jcb.201811014

PMCID:: PMC7199855

Article PDF–14M

Select item 47396095.

EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells

Atsuhiro Nakajo, Shin-ichiro Yoshimura, Hiroko Togawa, Masataka Kunii, Tomohiko Iwano, Ayaka Izumi, Yuria Noguchi, Ayako Watanabe, Ayako Goto, Toshiro Sato, Akihiro Harada

J Cell Biol. 2016 Feb 1; 212(3): 297–306. doi: 10.1083/jcb.201508086

PMCID:: PMC4739609

Article PDF–2.1M

Select item 39407286.

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence

Beate St Pourcain, David H Skuse, William P Mandy, Kai Wang, Hakon Hakonarson, Nicholas J Timpson, David M Evans, John P Kemp, Susan M Ring, Wendy L McArdle, Jean Golding, George Davey Smith

Mol Autism. 2014; 5: 18. Published online 2014 Feb 24. doi: 10.1186/2040-2392-5-18

PMCID:: PMC3940728

Article PDF–962K

Select item 27471997.

The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells

Liyun Zou, Jingran Zhou, Jinyu Zhang, Jingyi Li, Na Liu, Linlin Chai, Na Li, Ting Liu, Liqi Li, Zhunyi Xie, Hongli Liu, Ying Wan, Yuzhang Wu

Proc Natl Acad Sci U S A. 2009 Sep 15; 106(37): 15801–15806. Published online 2009 Aug 28. doi: 10.1073/pnas.0905684106

PMCID:: PMC2747199

Article PDF–1.7M

Select item 49105338.

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death

Chantal Sellier, Maria‐Letizia Campanari, Camille Julie Corbier, Angeline Gaucherot, Isabelle Kolb‐Cheynel, Mustapha Oulad‐Abdelghani, Frank Ruffenach, Adeline Page, Sorana Ciura, Edor Kabashi, Nicolas Charlet‐Berguerand

EMBO J. 2016 Jun 15; 35(12): 1276–1297. Published online 2016 Apr 21. doi: 10.15252/embj.201593350

PMCID:: PMC4910533

Article PDF–1.5M

Select item 29584689.

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors

Shin-ichiro Yoshimura, Andreas Gerondopoulos, Andrea Linford, Daniel J. Rigden, Francis A. Barr

J Cell Biol. 2010 Oct 18; 191(2): 367–381. doi: 10.1083/jcb.201008051

PMCID:: PMC2958468

Article PDF–9.0M

Select item 206485410.

Functional dissection of Rab GTPases involved in primary cilium formation

Shin-ichiro Yoshimura, Johannes Egerer, Evelyn Fuchs, Alexander K. Haas, Francis A. Barr

J Cell Biol. 2007 Jul 30; 178(3): 363–369. doi: 10.1083/jcb.200703047

PMCID:: PMC2064854

Article PDF–3.8M

Select item 752672211.

Phosphorylated tau interactome in the human Alzheimer’s disease brain

Eleanor Drummond, Geoffrey Pires, Claire MacMurray, Manor Askenazi, Shruti Nayak, Marie Bourdon, Jiri Safar, Beatrix Ueberheide, Thomas Wisniewski

Brain. 2020 Sep; 143(9): 2803–2817. Published online 2020 Aug 19. doi: 10.1093/brain/awaa223

PMCID:: PMC7526722

Article PDF–1.1M

Select item 353489112.

SGTA recognizes a non-canonical ubiquitin-like domain in the Bag6-Ubl4A-Trc35 complex to promote ER-associated degradation

Yue Xu, Mengli Cai, Yingying Yang, Lan Huang, Yihong Ye

Cell Rep. Author manuscript; available in PMC 2013 Jan 3.

Published in final edited form as: Cell Rep. 2012 Dec 27; 2(6): 1633–1644. Published online 2012 Dec 13. doi: 10.1016/j.celrep.2012.11.010

PMCID:: PMC3534891

Article PDF–3.0M

Select item 885704913.

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration

Tara E. Tracy, Jesus Madero-Pérez, Danielle L. Swaney, Timothy S. Chang, Michelle Moritz, Csaba Konrad, Michael E. Ward, Erica Stevenson, Ruth Hüttenhain, Grant Kauwe, Maria Mercedes, Lauren Sweetland-Martin, Xu Chen, Sue-Ann Mok, Man Ying Wong, Maria Telpoukhovskaia, Sang-Won Min, Chao Wang, Peter Dongmin Sohn, Jordie Martin, Yungui Zhou, Wenjie Luo, John Q. Trojanowski, Virginia M.Y. Lee, Shiaoching Gong, Giovanni Manfredi, Giovanni Coppola, Nevan J. Krogan, Daniel H. Geschwind, Li Gan

Cell. Author manuscript; available in PMC 2022 Feb 19.

Published in final edited form as: Cell. 2022 Feb 17; 185(4): 712–728.e14. Published online 2022 Jan 20. doi: 10.1016/j.cell.2021.12.041

PMCID:: PMC8857049

Article PDF–3.6M

Select item 294347614.

Genetic Variants in Nuclear-Encoded Mitochondrial Genes Influence AIDS Progression

Sher L. Hendrickson, James A. Lautenberger, Leslie Wei Chinn, Michael Malasky, Efe Sezgin, Lawrence A. Kingsley, James J. Goedert, Gregory D. Kirk, Edward D. Gomperts, Susan P. Buchbinder, Jennifer L. Troyer, Stephen J. O'Brien

PLoS One. 2010; 5(9): e12862. Published online 2010 Sep 21. doi: 10.1371/journal.pone.0012862

PMCID:: PMC2943476

Article PDF–461K

Select item 979798815.

TBK1 posphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1

Jianwen Zhou, Nikoline Lander Rasmussen, Hallvard Lauritz Olsvik, Vyacheslav Akimov, Zehan Hu, Gry Evjen, Stéphanie Kaeser-Pebernard, Devanarayanan Siva Sankar, Carole Roubaty, Pauline Verlhac, Nicole van de Beek, Fulvio Reggiori, Yakubu Princely Abudu, Blagoy Blagoev, Trond Lamark, Terje Johansen, Jörn Dengjel

J Cell Biol. 2023 Feb 6; 222(2): e202108144. Published online 2022 Dec 27. doi: 10.1083/jcb.202108144

PMCID:: PMC9797988

Article PDF–6.9M

Select item 599939616.

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation

Tyler B Faust, Yang Li, Curtis W Bacon, Gwendolyn M Jang, Amit Weiss, Bhargavi Jayaraman, Billy W Newton, Nevan J Krogan, Iván D'Orso, Alan D Frankel

eLife. 2018; 7: e31879. Published online 2018 May 30. doi: 10.7554/eLife.31879

PMCID:: PMC5999396

Article PDF–3.6M

Select item 570387817.

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery

Ramesh Kumar, Román González-Prieto, Zhenyu Xiao, Matty Verlaan-de Vries, Alfred C. O. Vertegaal

Nat Commun. 2017; 8: 1809. Published online 2017 Nov 27. doi: 10.1038/s41467-017-01900-x

PMCID:: PMC5703878

Article PDF–3.7M

Select item 739233418.

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells

Seung W. Ryu, Rose Stewart, D. Chase Pectol, Nicolette A. Ender, Oshadi Wimalarathne, Ji-Hoon Lee, Carlos P. Zanini, Antony Harvey, Jon M. Huibregtse, Peter Mueller, Tanya T. Paull

PLoS Biol. 2020 Jul; 18(7): e3000606. Published online 2020 Jul 20. doi: 10.1371/journal.pbio.3000606

PMCID:: PMC7392334

Article PDF–2.7M

Select item 464794119.

hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes

Philippe Lamesch, Ning Li, Stuart Milstein, Changyu Fan, Tong Hao, Gabor Szabo, Zhenjun Hu, Kavitha Venkatesan, Graeme Bethel, Paul Martin, Jane Rogers, Stephanie Lawlor, Stuart McLaren, Amélie Dricot, Heather Borick, Michael E. Cusick, Jean Vandenhaute, Ian Dunham, David E. Hill, Marc Vidal

Genomics. 2007 Mar; 89(3): 307–315. doi: 10.1016/j.ygeno.2006.11.012

PMCID:: PMC4647941

Article

Select item 319082620.

Interactions of Pathological Hallmark Proteins: TUBULIN POLYMERIZATION PROMOTING PROTEIN/p25, β-AMYLOID, AND α-SYNUCLEIN

Judit Oláh, Orsolya Vincze, Dezső Virók, Dóra Simon, Zsolt Bozsó, Natália Tőkési, István Horváth, Emma Hlavanda, János Kovács, Anna Magyar, Mária Szűcs, Ferenc Orosz, Botond Penke, Judit Ovádi

J Biol Chem. 2011 Sep 30; 286(39): 34088–34100. Published online 2011 Aug 8. doi: 10.1074/jbc.M111.243907

PMCID:: PMC3190826

Article PDF–5.7M

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