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Select item 106427611.

The mammalian Sterile 20-like kinase 4 (MST4) signaling in tumor progression: Implications for therapy

Ayechew A. Getu, Ming Zhou, Shi-Yuan Cheng, Ming Tan

Cancer Lett. Author manuscript; available in PMC 2023 Dec 1.

Published in final edited form as: Cancer Lett. 2023 Jun 1; 563: 216183. Published online 2023 Apr 22. doi: 10.1016/j.canlet.2023.216183

PMCID:: PMC10642761

Article PDF–872K

Select item 97773862.

MST4: A Potential Oncogene and Therapeutic Target in Breast Cancer

Ritu Arora, Jin-Hwan Kim, Ayechew A. Getu, Anusha Angajala, Yih-Lin Chen, Bin Wang, Andrea G. Kahn, Hong Chen, Latif Reshi, Jianrong Lu, Wenling Zhang, Ming Zhou, Ming Tan

Cells. 2022 Dec; 11(24): 4057. Published online 2022 Dec 15. doi: 10.3390/cells11244057

PMCID:: PMC9777386

Article PDF–4.1M

Select item 45806533.

Mammalian Ste20-Like Kinase 4 Promotes Pituitary Cell Proliferation and Survival Under Hypoxia

Weipeng Xiong, Aaron J. Knox, Mei Xu, Katja Kiseljak-Vassiliades, Sean P. Colgan, Kelley S. Brodsky, Bette K. Kleinschmidt-Demasters, Kevin O. Lillehei, Margaret E. Wierman

Mol Endocrinol. 2015 Mar; 29(3): 460–472. Published online 2015 Feb 4. doi: 10.1210/me.2014-1332

PMCID:: PMC4580653

Article

Select item 74153004.

Downregulation of MST4 Underlies a Novel Inhibitory Role of MicroRNA Let-7a in the Progression of Retinoblastoma

Xinli Zhang, Lili Song, Yanxia Huang, Shaoping Han, Min Hou, Hongxia Li

Invest Ophthalmol Vis Sci. 2020 Jun; 61(6): 28. Published online 2020 Jun 15. doi: 10.1167/iovs.61.6.28

PMCID:: PMC7415300

Article PDF–6.3M

Select item 57349345.

MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

Tianzhi Huang, Chung Kwon Kim, Angel A. Alvarez, Rajendra P. Pangeni, Xuechao Wan, Xiao Song, Taiping Shi, Yongyong Yang, Namratha Sastry, Craig M. Horbinski, Songjian Lu, Roger Stupp, John A. Kessler, Ryo Nishikawa, Ichiro Nakano, Erik P. Sulman, Xinghua Lu, Charles David James, Xiao-Ming Yin, Bo Hu, Shi-Yuan Cheng

Cancer Cell. 2017 Dec 11; 32(6): 840–855.e8. doi: 10.1016/j.ccell.2017.11.005

PMCID:: PMC5734934

Article

Select item 53227926.

MST-4 and TRAF-6 expression in the peripheral blood mononuclear cells of patients with Graves’ disease and its significance

Ai Guo, Yan Tan, Chun Liu, Xiaoya Zheng

BMC Endocr Disord. 2017; 17: 11. Published online 2017 Feb 20. doi: 10.1186/s12902-017-0161-y

PMCID:: PMC5322792

Article PDF–729K

Select item 38988417.

Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

Catherine Chen, Byung Hak Ha, Anastasia F. Thévenin, Hua Jane Lou, Rong Zhang, Kevin Y. Yip, Jeffrey R. Peterson, Mark Gerstein, Philip M. Kim, Panagis Filippakopoulos, Stefan Knapp, Titus J. Boggon, Benjamin E. Turk

Mol Cell. 2014 Jan 9; 53(1): 140–147. doi: 10.1016/j.molcel.2013.11.013

PMCID:: PMC3898841

Article PDF–786K

Select item 33889158.

Crystallization and preliminary crystallographic studies of CCM3 in complex with the C-terminal domain of MST4

Xueyong Xu, Xiaoyan Wang, Jingjin Ding, Da-Cheng Wang

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1; 68(Pt 7): 760–763. Published online 2012 Jun 27. doi: 10.1107/S1744309112016843

PMCID:: PMC3388915

Article PDF–399K

Select item 68265869.

Common Nevus and Skin Cutaneous Melanoma: Prognostic Genes Identified by Gene Co-Expression Network Analysis

Lingge Yang, Yu Xu, Yan Yan, Peng Luo, Shiqi Chen, Biqiang Zheng, Wangjun Yan, Yong Chen, Chunmeng Wang

Genes (Basel) 2019 Oct; 10(10): 747. Published online 2019 Sep 25. doi: 10.3390/genes10100747

PMCID:: PMC6826586

Article PDF–2.6M

Select item 427062810.

Differential expression of MST4, STK25 and PDCD10 between benign prostatic hyperplasia and prostate cancer

Heyu Zhang, Xi Ma, Saihui Peng, Xu Nan, Hongshan Zhao

Int J Clin Exp Pathol. 2014; 7(11): 8105–8111. Published online 2014 Oct 15.

PMCID:: PMC4270628

Article PDF–655K

Select item 797113711.

MST4 kinase suppresses gastric tumorigenesis by limiting YAP activation via a non-canonical pathway

Liwei An, Pingping Nie, Min Chen, Yang Tang, Hui Zhang, Jingmin Guan, Zhifa Cao, Chun Hou, Wenjia Wang, Yun Zhao, Huixiong Xu, Shi Jiao, Zhaocai Zhou

J Exp Med. 2020 Jun 1; 217(6): e20191817. Published online 2020 Apr 9. doi: 10.1084/jem.20191817

PMCID:: PMC7971137

Article PDF–6.0M

Select item 613955812.

The MST4–MOB4 complex disrupts the MST1–MOB1 complex in the Hippo–YAP pathway and plays a pro-oncogenic role in pancreatic cancer

Min Chen, Hui Zhang, Zhubing Shi, Yehua Li, Xiaoman Zhang, Ziyang Gao, Li Zhou, Jian Ma, Qi Xu, Jingmin Guan, Yunfeng Cheng, Shi Jiao, Zhaocai Zhou

J Biol Chem. 2018 Sep 14; 293(37): 14455–14469. Published online 2018 Aug 2. doi: 10.1074/jbc.RA118.003279

PMCID:: PMC6139558

Article PDF–5.0M

Select item 187709113.

PDCD10 Interacts with Ste20-related Kinase MST4 to Promote Cell Growth and Transformation via Modulation of the ERK Pathway

Xi Ma, Hongshan Zhao, Jingxuan Shan, Feng Long, Yaoyao Chen, Yingyu Chen, Yingmei Zhang, Xiao Han, Dalong Ma

Mol Biol Cell. 2007 Jun; 18(6): 1965–1978. doi: 10.1091/mbc.E06-07-0608

PMCID:: PMC1877091

Article PDF–2.7M

Select item 927418714.

MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway

Wei Liu, Zhenling Ma, Yaru Wu, Cui Yuan, Yanyan Zhang, Zeyang Liang, Yu Yang, Wenwen Zhang, Pengtao Jiao

Cell Commun Signal. 2022; 20: 103. Published online 2022 Jul 12. doi: 10.1186/s12964-022-00922-3

PMCID:: PMC9274187

Article PDF–5.7M

Select item 313707915.

CCM3/PDCD10 Heterodimerizes with Germinal Center Kinase III (GCKIII) Proteins Using a Mechanism Analogous to CCM3 Homodimerization

Derek F. Ceccarelli, Rob C. Laister, Vikram Khipple Mulligan, Michelle J. Kean, Marilyn Goudreault, Ian C. Scott, W. Brent Derry, Avijit Chakrabartty, Anne-Claude Gingras, Frank Sicheri

J Biol Chem. 2011 Jul 15; 286(28): 25056–25064. Published online 2011 May 11. doi: 10.1074/jbc.M110.213777

PMCID:: PMC3137079

Article PDF–2.4M

Select item 310198916.

MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases

Beatrice M Filippi, Paola de los Heros, Youcef Mehellou, Iva Navratilova, Robert Gourlay, Maria Deak, Lorna Plater, Rachel Toth, Elton Zeqiraj, Dario R Alessi

EMBO J. 2011 May 4; 30(9): 1730–1741. Published online 2011 Mar 18. doi: 10.1038/emboj.2011.78

PMCID:: PMC3101989

Article PDF–740K

Select item 842590117.

An MST4‐pβ‐Catenin^Thr40 Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis

Hui Zhang, Moubin Lin, Chao Dong, Yang Tang, Liwei An, Junyi Ju, Fuping Wen, Fan Chen, Meng Wang, Wenjia Wang, Min Chen, Yun Zhao, Jixi Li, Steven X. Hou, Xinhua Lin, Lulu Hu, Wenbo Bu, Dianqing Wu, Lin Li, Shi Jiao, Zhaocai Zhou

Adv Sci (Weinh) 2021 Sep; 8(17): 2004850. Published online 2021 Jul 8. doi: 10.1002/advs.202004850