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Select item 100157691.

Comprehensive analysis of the biological function and immune infiltration of SLC38A2 in gastric cancer

Liang Zhu, Zhengguang Wang, Wenxiu Han, Aman Xu

BMC Gastroenterol. 2023; 23: 74. Published online 2023 Mar 14. doi: 10.1186/s12876-023-02689-4

PMCID:: PMC10015769

Abstract Article PDF–7.4M

Select item 78525312.

Increased expression of glutamine transporter SNAT2/SLC38A2 promotes glutamine dependence and oxidative stress resistance, and is associated with worse prognosis in triple-negative breast cancer

Matteo Morotti, Christos E. Zois, Rokaya El-Ansari, Madeleine L. Craze, Emad A. Rakha, Shih-Jung Fan, Alessandro Valli, Syed Haider, Deborah C. I. Goberdhan, Andrew R. Green, Adrian L. Harris

Br J Cancer. 2021 Jan 19; 124(2): 494–505. Published online 2020 Oct 8. doi: 10.1038/s41416-020-01113-y

PMCID:: PMC7852531

Abstract Article PDF–3.9M

Select item 65897523.

Hypoxia-induced switch in SNAT2/SLC38A2 regulation generates endocrine resistance in breast cancer

Matteo Morotti, Esther Bridges, Alessandro Valli, Hani Choudhry, Helen Sheldon, Simon Wigfield, Nicki Gray, Christos E. Zois, Fiona Grimm, Dylan Jones, Eugene J. Teoh, Wei-Chen Cheng, Simon Lord, Dimitrios Anastasiou, Syed Haider, Alan McIntyre, Deborah C. I. Goberdhan, Francesca Buffa, Adrian L. Harris

Proc Natl Acad Sci U S A. 2019 Jun 18; 116(25): 12452–12461. Published online 2019 May 31. doi: 10.1073/pnas.1818521116

PMCID:: PMC6589752

Abstract Article PDF–2.4M

Select item 46140274.

Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR

Yi-Yung Chen, Fredrick J. Rosario, Majida Abu Shehab, Theresa L. Powell, Madhulika B. Gupta, Thomas Jansson

Clin Sci (Lond) 2015 Dec 1; 129(12): 1131–1141. Prepublished online 2015 Sep 15. Published online 2015 Oct 22. doi: 10.1042/CS20150511

PMCID:: PMC4614027

Abstract Article PDF–813K

Select item 43754745.

Proteasomal Modulation of Cellular SNAT2 (SLC38A2) Abundance and Function by Unsaturated Fatty Acid Availability

Francesca Nardi, Thorsten M. Hoffmann, Clare Stretton, Emma Cwiklinski, Peter M. Taylor, Harinder S. Hundal

J Biol Chem. 2015 Mar 27; 290(13): 8173–8184. Published online 2015 Feb 4. doi: 10.1074/jbc.M114.625137

PMCID:: PMC4375474

Abstract Article PDF–3.0M

Select item 33409006.

Effect of maternal age and growth on placental nutrient transport: potential mechanisms for teenagers' predisposition to small-for-gestational-age birth?

Christina E. Hayward, Susan L. Greenwood, Colin P. Sibley, Philip N. Baker, John R. G. Challis, Rebecca L. Jones

Am J Physiol Endocrinol Metab. 2012 Jan 15; 302(2): E233–E242. Published online 2011 Oct 25. doi: 10.1152/ajpendo.00192.2011

PMCID:: PMC3340900

Abstract Article

Select item 32092617.

Requirement of rRNA Methylation for 80S Ribosome Assembly on a Cohort of Cellular Internal Ribosome Entry Sites

Abhijit Basu, Priyanka Das, Sujan Chaudhuri, Elena Bevilacqua, Joel Andrews, Sailen Barik, Maria Hatzoglou, Anton A. Komar, Barsanjit Mazumder

Mol Cell Biol. 2011 Nov; 31(22): 4482–4499. doi: 10.1128/MCB.05804-11

PMCID:: PMC3209261

Abstract Article PDF–3.8M

Select item 18648458.

The Sodium-Coupled Neutral Amino Acid Transporter SNAT2 Mediates an Anion Leak Conductance that Is Differentially Inhibited by Transported Substrates

Zhou Zhang, Christof Grewer

Biophys J. 2007 Apr 1; 92(7): 2621–2632. Published online 2007 Jan 19. doi: 10.1529/biophysj.106.100776

PMCID:: PMC1864845

Abstract Article PDF–1012K

Select item 106445009.

CHOP upregulation and dysregulation of the mature form of the SNAT2 amino acid transporter in the placentas from small for gestational age newborns

Emma Barroso, Marta Díaz, Ana Cristina Reguera, Mona Peyman, Jesús Balsinde, Javier Jurado-Aguilar, Meijian Zhang, Adel Rostami, Xavier Palomer, Lourdes Ibáñez, Manuel Vázquez-Carrera

Cell Commun Signal. 2023; 21: 326. Published online 2023 Nov 13. doi: 10.1186/s12964-023-01352-5

PMCID:: PMC10644500

Abstract Article PDF–2.5M

Select item 1020021210.

Hsa_circRNA_001859 regulates pancreatic cancer progression and epithelial-mesenchymal transition through the miR-21-5p/SLC38A2 pathway

Liang Li, Nan Wang, Jun Wang, Jiangang Li

Cancer Biomark. 2023; 37(1): 39–52. Prepublished online 2023 Mar 22. Published online 2023 May 15. doi: 10.3233/CBM-220229

PMCID:: PMC10200212

Abstract Article PDF–10M

Select item 862401111.

LAT1 and SNAT2 Protein Expression and Membrane Localization of LAT1 Are Not Acutely Altered by Dietary Amino Acids or Resistance Exercise Nor Positively Associated with Leucine or Phenylalanine Incorporation in Human Skeletal Muscle

Michael Mazzulla, Nathan Hodson, Matthew Lees, Paula J. Scaife, Kenneth Smith, Philip J. Atherton, Dinesh Kumbhare, Daniel R. Moore

Nutrients. 2021 Nov; 13(11): 3906. Published online 2021 Oct 30. doi: 10.3390/nu13113906

PMCID:: PMC8624011

Abstract Article PDF–3.7M

Select item 708468412.

Functional Consequences of Low Activity of Transport System A for Neutral Amino Acids in Human Bone Marrow Mesenchymal Stem Cells

Martina Chiu, Giuseppe Taurino, Massimiliano G. Bianchi, Erica Dander, Alessandra Fallati, Nicola Giuliani, Giovanna D’Amico, Ovidio Bussolati

Int J Mol Sci. 2020 Mar; 21(5): 1899. Published online 2020 Mar 10. doi: 10.3390/ijms21051899

PMCID:: PMC7084684

Abstract Article PDF–2.0M

Select item 492716213.

Identification of a Disulfide Bridge in Sodium-Coupled Neutral Amino Acid Transporter 2(SNAT2) by Chemical Modification

Chen Chen, Jiahong Wang, Ruiping Cai, Yanmeng Yuan, Zhanyun Guo, Christof Grewer, Zhou Zhang

PLoS One. 2016; 11(6): e0158319. Published online 2016 Jun 29. doi: 10.1371/journal.pone.0158319

PMCID:: PMC4927162

Abstract Article PDF–1.9M

Select item 356715414.

Plasmodium falciparum Malaria Elicits Inflammatory Responses that Dysregulate Placental Amino Acid Transport

Philippe Boeuf, Elizabeth H. Aitken, Upeksha Chandrasiri, Caroline Lin Lin Chua, Bernie McInerney, Leon McQuade, Michael Duffy, Malcolm Molyneux, Graham Brown, Jocelyn Glazier, Stephen J. Rogerson

PLoS Pathog. 2013 Feb; 9(2): e1003153. Published online 2013 Feb 7. doi: 10.1371/journal.ppat.1003153

PMCID:: PMC3567154

Abstract Article PDF–371K

Select item 328536915.

Functional RNA Interference (RNAi) Screen Identifies System A Neutral Amino Acid Transporter 2 (SNAT2) as a Mediator of Arsenic-induced Endoplasmic Reticulum Stress

Raymond S. Oh, Wen-Chi Pan, Abdullah Yalcin, Hong Zhang, Tomás R. Guilarte, Gökhan S. Hotamisligil, David C. Christiani, Quan Lu

J Biol Chem. 2012 Feb 17; 287(8): 6025–6034. Published online 2012 Jan 3. doi: 10.1074/jbc.M111.311217

PMCID:: PMC3285369

Abstract Article PDF–1.6M

Select item 275723316.

A Conserved Na⁺ Binding Site of the Sodium-coupled Neutral Amino Acid Transporter 2 (SNAT2)

Zhou Zhang, Thomas Albers, Heather L. Fiumera, Armanda Gameiro, Christof Grewer

J Biol Chem. 2009 Sep 11; 284(37): 25314–25323. Published online 2009 Jul 9. doi: 10.1074/jbc.M109.038422

PMCID:: PMC2757233

Abstract Article PDF–2.6M

Select item 493323317.

Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells

Angelika Bröer, Farid Rahimi, Stefan Bröer

J Biol Chem. 2016 Jun 17; 291(25): 13194–13205. Published online 2016 Apr 26. doi: 10.1074/jbc.M115.700534

PMCID:: PMC4933233

Abstract Article PDF–1.5M

Select item 450503318.

Coordinated Regulation of the Neutral Amino Acid Transporter SNAT2 and the Protein Phosphatase Subunit GADD34 Promotes Adaptation to Increased Extracellular Osmolarity

Dawid Krokowski, Raul Jobava, Bo-Jhih Guan, Kenneth Farabaugh, Jing Wu, Mithu Majumder, Massimiliano G. Bianchi, Martin D. Snider, Ovidio Bussolati, Maria Hatzoglou

J Biol Chem. 2015 Jul 17; 290(29): 17822–17837. Published online 2015 Jun 3. doi: 10.1074/jbc.M114.636217

PMCID:: PMC4505033

Abstract Article PDF–4.4M

Select item 435690319.

Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-inducing Chemotherapies

Young Joo Jeon, Sihem Khelifa, Boris Ratnikov, David A. Scott, Yongmei Feng, Fabio Parisi, Chelsea Ruller, Eric Lau, Hyungsoo Kim, Laurence M. Brill, Tingting Jiang, David Rimm, Robert D. Cardiff, Gordon B. Mills, Jeffrey W. Smith, Andrei L. Osterman, Yuval Kluger, Ze'ev A. Ronai

Cancer Cell. Author manuscript; available in PMC 2016 Mar 9.

Published in final edited form as: Cancer Cell. 2015 Mar 9; 27(3): 354–369. doi: 10.1016/j.ccell.2015.02.006

PMCID:: PMC4356903

Abstract Article PDF–1.7M

Select item 256205820.

Despite Increased ATF4 Binding at the C/EBP-ATF Composite Site following Activation of the Unfolded Protein Response, System A Transporter 2 (SNAT2) Transcription Activity Is Repressed in HepG2 Cells

Altin Gjymishka, Stela S. Palii, Jixiu Shan, Michael S. Kilberg

J Biol Chem. 2008 Oct 10; 283(41): 27736–27747. doi: 10.1074/jbc.M803781200

PMCID:: PMC2562058

Abstract Article PDF–924K

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