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Select item 109427831.

WRNIP1 prevents transcription-associated genomic instability

Pasquale Valenzisi, Veronica Marabitti, Pietro Pichierri, Annapaola Franchitto

eLife. 2024; 12: RP89981. Published online 2024 Mar 15. doi: 10.7554/eLife.89981

PMCID:: PMC10942783

Abstract Article PDF–11M

Select item 73511112.

WRNIP1 Is Recruited to DNA Interstrand Crosslinks and Promotes Repair

Anna Socha, Di Yang, Alicja Bulsiewicz, Kelvin Yaprianto, Marian Kupculak, Chih-Chao Liang, Andreas Hadjicharalambous, Ronghu Wu, Steven P. Gygi, Martin A. Cohn

Cell Rep. 2020 Jul 7; 32(1): 107850. Published online 2020 Jul 7. doi: 10.1016/j.celrep.2020.107850

PMCID:: PMC7351111

Abstract Article

Select item 49311873.

WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress

Giuseppe Leuzzi, Veronica Marabitti, Pietro Pichierri, Annapaola Franchitto

EMBO J. 2016 Jul 1; 35(13): 1437–1451. Published online 2016 May 30. doi: 10.15252/embj.201593265

PMCID:: PMC4931187

Abstract Article PDF–2.3M

Select item 88361294.

R-Loop-Associated Genomic Instability and Implication of WRN and WRNIP1

Veronica Marabitti, Pasquale Valenzisi, Giorgia Lillo, Eva Malacaria, Valentina Palermo, Pietro Pichierri, Annapaola Franchitto

Int J Mol Sci. 2022 Feb; 23(3): 1547. Published online 2022 Jan 28. doi: 10.3390/ijms23031547

PMCID:: PMC8836129

Abstract Article PDF–1.4M

Select item 67717395.

miR‐22enhances the radiosensitivity of small‐cell lung cancer by targeting theWRNIP1

Wenhua Jiang, Xuemei Han, Jingrui Wang, Lin Wang, Zanmei Xu, Qiao Wei, Wenpan Zhang, Haitao Wang

J Cell Biochem. 2019 Oct; 120(10): 17650–17661. Published online 2019 Jun 12. doi: 10.1002/jcb.29032

PMCID:: PMC6771739

Abstract Article PDF–1.7M

Select item 32598976.

Human Wrnip1 Is Localized in Replication Factories in a Ubiquitin-binding Zinc Finger-dependent Manner

Nicola Crosetto, Marzena Bienko, Richard G. Hibbert, Tina Perica, Chiara Ambrogio, Tobias Kensche, Kay Hofmann, Titia K. Sixma, Ivan Dikic

J Biol Chem. 2008 Dec 12; 283(50): 35173–35185. doi: 10.1074/jbc.M803219200

PMCID:: PMC3259897

Abstract Article PDF–1.3M

Select item 48420107.

RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress

Nnennaya Kanu, Tianyi Zhang, Rebecca A. Burrell, Atanu Chakraborty, Janet Cronshaw, Clive Da Costa, Eva Grönroos, Helen N. Pemberton, Emma Anderton, Laure Gonzalez, Simone Sabbioneda, Helle D. Ulrich, Charles Swanton, Axel Behrens

Oncogene. Author manuscript; available in PMC 2016 Sep 22.

Published in final edited form as: Oncogene. 2016 Jul 28; 35(30): 4009–4019. Published online 2015 Nov 9. doi: 10.1038/onc.2015.427

Correction in:: Oncogene. 2016 Jul 28; 35(30): 4020.

PMCID:: PMC4842010

Abstract Article PDF–2.0M

Select item 34946568.

Identification of novel CDK9 and Cyclin T1-associated protein complexes (CCAPs) whose siRNA depletion enhances HIV-1 Tat function

Rajesh Ramakrishnan, Hongbing Liu, Hart Donahue, Anna Malovannaya, Jun Qin, Andrew P Rice

Retrovirology. 2012; 9: 90. Published online 2012 Oct 30. doi: 10.1186/1742-4690-9-90

PMCID:: PMC3494656

Abstract Article PDF–1.8M

Select item 44218749.

Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser¹⁶ to trigger its nuclear localization

Lina Herhaus, Ana B. Perez-Oliva, Giorgio Cozza, Robert Gourlay, Simone Weidlich, David G. Campbell, Lorenzo A. Pinna, Gopal P. Sapkota

Sci Signal. Author manuscript; available in PMC 2015 Oct 14.

Published in final edited form as: Sci Signal. 2015; 8(372): ra35. Published online 2015 Apr 14. doi: 10.1126/scisignal.aaa0441

PMCID:: PMC4421874

Abstract Article PDF–3.4M

Select item 569108310.

Autophagy acts through TRAF3 and RELB to regulate gene expression via antagonism of SMAD proteins

Alice C. Newman, Alain J. Kemp, Yvette Drabsch, Christian Behrends, Simon Wilkinson

Nat Commun. 2017; 8: 1537. Published online 2017 Nov 16. doi: 10.1038/s41467-017-00859-z

PMCID:: PMC5691083

Abstract Article PDF–2.3M

Select item 675444611.

Regulation of the endosomal SNX27-retromer by OTULIN

Aurelia Stangl, Paul R. Elliott, Adan Pinto-Fernandez, Sarah Bonham, Luke Harrison, Annalisa Schaub, Kerstin Kutzner, Kirstin Keusekotten, Paul T. Pfluger, Farid El Oualid, Benedikt M. Kessler, David Komander, Daniel Krappmann

Nat Commun. 2019; 10: 4320. Published online 2019 Sep 20. doi: 10.1038/s41467-019-12309-z

PMCID:: PMC6754446

Abstract Article PDF–6.0M

Select item 970452712.

Co-ordinated control of the ADP-heptose/ALPK1 signalling network by the E3 ligases TRAF6, TRAF2/c-IAP1 and LUBAC

Tom Snelling, Natalia Shpiro, Robert Gourlay, Frederic Lamoliatte, Philip Cohen

Biochem J. 2022 Oct 28; 479(20): 2195–2216. Published online 2022 Oct 21. doi: 10.1042/BCJ20220401

PMCID:: PMC9704527

Abstract Article PDF–7.7M

Select item 471231413.

Proteomic data on the nuclear interactome of human MCM9

James R.A. Hutchins, Sabine Traver, Philippe Coulombe, Isabelle Peiffer, Magali Kitzmann, Daniel Latreille, Marcel Méchali

Data Brief. 2016 Mar; 6: 410–415. Published online 2015 Dec 11. doi: 10.1016/j.dib.2015.11.055

PMCID:: PMC4712314

Abstract Article PDF–233K

Select item 822225614.

ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress

Yu-Ching Teng, Aishwarya Sundaresan, Ryan O’Hara, Vincent U. Gant, Minhua Li, Sara Martire, Jane N. Warshaw, Amrita Basu, Laura A. Banaszynski

Nat Commun. 2021; 12: 3887. Published online 2021 Jun 23. doi: 10.1038/s41467-021-24206-5

PMCID:: PMC8222256

Abstract Article PDF–2.5M

Select item 359166515.

Identification of the Hypoxia-inducible Factor 2α Nuclear Interactome in Melanoma Cells Reveals Master Proteins Involved in Melanoma Development

Anne-Lise Steunou, Manuelle Ducoux-Petit, Ikrame Lazar, Bernard Monsarrat, Monique Erard, Catherine Muller, Eric Clottes, Odile Burlet-Schiltz, Laurence Nieto

Mol Cell Proteomics. 2013 Mar; 12(3): 736–748. Published online 2012 Dec 28. doi: 10.1074/mcp.M112.020727

PMCID:: PMC3591665

Abstract Article PDF–3.0M

Select item 270004816.

Identification of Novel Smad2 and Smad3 Associated Proteins in Response to TGF-β1

Kimberly A. Brown, Amy-Joan L. Ham, Cara N. Clark, Nahum Meller, Brian K. Law, Anna Chytil, Nikki Cheng, Jennifer A. Pietenpol, Harold L. Moses

J Cell Biochem. Author manuscript; available in PMC 2009 Oct 1.

Published in final edited form as: J Cell Biochem. 2008 Oct 1; 105(2): 596–611. doi: 10.1002/jcb.21860

PMCID:: PMC2700048

Abstract Article PDF–1.1M

Select item 890611917.

WWP1 upregulation predicts poor prognosis and promotes tumor progression by regulating ubiquitination of NDFIP1 in intrahepatic cholangiocarcinoma

Yongjian Li, Qian Cheng, Jie Gao, Zhuomiaoyu Chen, Jingheng Guo, Zuyin Li, Lingyu Tian, Chao Zhang, Yuzi Li, Jiaxi Zheng, Zhao Li, Jiye Zhu

Cell Death Discov. 2022; 8: 107. Published online 2022 Mar 9. doi: 10.1038/s41420-022-00882-0

PMCID:: PMC8906119

Abstract Article PDF–6.1M

Select item 596114118.

Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells

Benoit Miotto, Claire Marchal, Guillaume Adelmant, Nadège Guinot, Ping Xie, Jarrod A Marto, Lingqiang Zhang, Pierre-Antoine Defossez

Nucleic Acids Res. 2018 May 18; 46(9): 4392–4404. Published online 2018 Feb 27. doi: 10.1093/nar/gky149

PMCID:: PMC5961141

Abstract Article PDF–2.1M

Select item 875018619.

mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells

David A. Merle, Francesca Provenzano, Mohamed Ali Jarboui, Ellen Kilger, Simon J. Clark, Michela Deleidi, Angela Armento, Marius Ueffing

Antioxidants (Basel) 2021 Dec; 10(12): 1944. Published online 2021 Dec 3. doi: 10.3390/antiox10121944

PMCID:: PMC8750186

Abstract Article PDF–2.7M

Select item 509166820.

Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation

Daniel C. Scott, David Y. Rhee, David M. Duda, Ian R. Kelsall, Jennifer L. Olszewski, Joao A. Paulo, Annemieke de Jong, Huib Ovaa, Arno F. Alpi, J. Wade Harper, Brenda A. Schulman

Cell. Author manuscript; available in PMC 2017 Aug 25.

Published in final edited form as: Cell. 2016 Aug 25; 166(5): 1198–1214.e24. doi: 10.1016/j.cell.2016.07.027