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Select item 39453111.

Shear Stress-induced Redistribution of Vascular Endothelial-Protein-tyrosine Phosphatase (VE-PTP) in Endothelial Cells and Its Role in Cell Elongation

Kemala Isnainiasih Mantilidewi, Yoji Murata, Munemasa Mori, Chihiro Otsubo, Takenori Kotani, Shinya Kusakari, Hiroshi Ohnishi, Takashi Matozaki

J Biol Chem. 2014 Mar 7; 289(10): 6451–6461. Published online 2014 Jan 22. doi: 10.1074/jbc.M113.529503

PMCID:: PMC3945311

Abstract Article PDF–2.8M

Select item 33087572.

Picomolar Concentrations of Free Zinc(II) Ions Regulate Receptor Protein-tyrosine Phosphatase β Activity

Matthew Wilson, Christer Hogstrand, Wolfgang Maret

J Biol Chem. 2012 Mar 16; 287(12): 9322–9326. Published online 2012 Jan 24. doi: 10.1074/jbc.C111.320796

PMCID:: PMC3308757

Abstract Article PDF–556K

Select item 11361243.

Increase in receptor-like protein tyrosine phosphatase activity and expression level on density-dependent growth arrest of endothelial cells.

F Gaits, R Y Li, A Ragab, J M Ragab-Thomas, H Chap

Biochem J. 1995 Oct 1; 311(Pt 1): 97–103. doi: 10.1042/bj3110097

PMCID:: PMC1136124

Summary Page Browse PDF–1.4M

Select item 64914934.

PTPRB promotes metastasis of colorectal carcinoma via inducing epithelial-mesenchymal transition

Xingyue Weng, Wei Chen, Wangxiong Hu, Kailun Xu, Lina Qi, Jiani Chen, Demin Lu, Yinkuan Shao, Xi Zheng, Chenyang Ye, Shu Zheng

Cell Death Dis. 2019 May; 10(5): 352. Published online 2019 Apr 30. doi: 10.1038/s41419-019-1554-9

PMCID:: PMC6491493

Abstract Article PDF–5.2M

Select item 96662125.

The variants in PTPRB, TRAF3IP3, and DISC1 genes were associated with Graves’ disease in the Chinese population

Wei Li, Haidong Jiang, Xu Chen, Kevin Yang, Xindan Deng, Zheng Tang, Zhihui Hu, Xiaodan Zhang, Shihan Lin, Yuanlin Zou, Hui Wu

Medicine (Baltimore) 2022 Nov 11; 101(45): e31501. Published online 2022 Nov 11. doi: 10.1097/MD.0000000000031501

PMCID:: PMC9666212

Abstract Article PDF–527K

Select item 69073376.

miR-624-5p promoted tumorigenesis and metastasis by suppressing hippo signaling through targeting PTPRB in osteosarcoma cells

Yongjun Luo, Wei Liu, Pengyu Tang, Dongdong Jiang, Changjiang Gu, Yumin Huang, Fangyi Gong, Yuluo Rong, Dingfei Qian, Jian Chen, Zheng Zhou, Shujie Zhao, Jiaxing Wang, Tao Xu, Yongzhong Wei, Guoyong Yin, Jin Fan, Weihua Cai

J Exp Clin Cancer Res. 2019; 38: 488. Published online 2019 Dec 11. doi: 10.1186/s13046-019-1491-6

PMCID:: PMC6907337

Abstract Article PDF–5.1M

Select item 67735587.

Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2

Hannes C. A. Drexler, Matthias Vockel, Christian Polaschegg, Maike Frye, Kevin Peters, Dietmar Vestweber

Mol Cell Proteomics. 2019 Oct; 18(10): 2058–2077. Published online 2019 Aug 19. doi: 10.1074/mcp.RA119.001716

PMCID:: PMC6773558

Abstract Article PDF–3.1M

Select item 61563858.

Collagen regulates the ability of endothelial progenitor cells to protect hypoxic myocardium through a mechanism involving miR‐377/VE‐PTP axis

Ana‐Maria Rosca, Daniel Nicolae Mitroi, Valeriu Cismasiu, Rodica Badea, Georgiana Necula‐Petrareanu, Mihai Bogdan Preda, Cristina Niculite, Raluca Tutuianu, Stefan Szedlacsek, Alexandrina Burlacu

J Cell Mol Med. 2018 Oct; 22(10): 4700–4708. Published online 2018 Jul 25. doi: 10.1111/jcmm.13712

PMCID:: PMC6156385

Abstract Article PDF–631K

Select item 40328739.

Recurrent PTPRB and PLCG1 mutations in angiosarcoma

Sam Behjati, Patrick S Tarpey, Helen Sheldon, Inigo Martincorena, Peter Van Loo, Gunes Gundem, David C Wedge, Manasa Ramakrishna, Susanna L Cooke, Nischalan Pillay, Hans Kristian M Vollan, Elli Papaemmanuil, Hans Koss, Tom D Bunney, Claire Hardy, Olivia R Joseph, Sancha Martin, Laura Mudie, Adam Butler, Jon W Teague, Meena Patil, Graham Steers, Yu Cao, Curtis Gumbs, Davis Ingram, Alexander J Lazar, Latasha Little, Harshad Mahadeshwar, Alexei Protopopov, Ghadah A Al Sannaa, Sahil Seth, Xingzhi Song, Jiabin Tang, Jianhua Zhang, Vinod Ravi, Keila E Torres, Bhavisha Khatri, Dina Halai, Ioannis Roxanis, Daniel Baumhoer, Roberto Tirabosco, M Fernanda Amary, Chris Boshoff, Ultan McDermott, Matilda Katan, Michael R Stratton, P Andrew Futreal, Adrienne M Flanagan, Adrian Harris, Peter J Campbell

Nat Genet. Author manuscript; available in PMC 2014 Oct 1.

Published in final edited form as: Nat Genet. 2014 Apr; 46(4): 376–379. Published online 2014 Mar 16. doi: 10.1038/ng.2921

PMCID:: PMC4032873

Abstract Article PDF–456K

Select item 213248810.

Induction of Neurite Outgrowth through Contactin and Nr-CAM by Extracellular Regions of Glial Receptor Tyrosine Phosphatase β

Takeshi Sakurai, Marc Lustig, Moshe Nativ, John J. Hemperly, Joseph Schlessinger, Elior Peles, Martin Grumet

J Cell Biol. 1997 Feb 24; 136(4): 907–918. doi: 10.1083/jcb.136.4.907

PMCID:: PMC2132488

Abstract Article PDF–769K

Select item 121776111.

Molecular cloning and characterization of PTP pi, a novel receptor-like protein-tyrosine phosphatase.

S Crossland, P D Smith, M R Crompton

Biochem J. 1996 Oct 1; 319(Pt 1): 249–254. doi: 10.1042/bj3190249

PMCID:: PMC1217761

Summary PDF–761K

Select item 419101112.

Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature

Jikui Shen, Maike Frye, Bonnie L. Lee, Jessica L. Reinardy, Joseph M. McClung, Kun Ding, Masashi Kojima, Huiming Xia, Christopher Seidel, Raquel Lima e Silva, Aling Dong, Sean F. Hackett, Jiangxia Wang, Brian W. Howard, Dietmar Vestweber, Christopher D. Kontos, Kevin G. Peters, Peter A. Campochiaro

J Clin Invest. 2014 Oct 1; 124(10): 4564–4576. Published online 2014 Sep 2. doi: 10.1172/JCI74527

PMCID:: PMC4191011

Abstract Article PDF–6.2M

Select item 1597513.

Pleiotrophin signals increased tyrosine phosphorylation of β-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase β/ζ

Kung Meng, A. Rodríguez-Peña, Todor Dimitrov, Wen Chen, Moshe Yamin, Masaharu Noda, Thomas F. Deuel

Proc Natl Acad Sci U S A. 2000 Mar 14; 97(6): 2603–2608. Published online 2000 Mar 7. doi: 10.1073/pnas.020487997

PMCID:: PMC15975

Abstract Article PDF–196K

Select item 549594314.

Pyk2 phosphorylation of VE-PTP downstream of STIM1-induced Ca²⁺ entry regulates disassembly of adherens junctions

Dheeraj Soni, Sushil C. Regmi, Dong-Mei Wang, Auditi DebRoy, You-Yang Zhao, Stephen M. Vogel, Asrar B. Malik, Chinnaswamy Tiruppathi

Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1; 312(6): L1003–L1017. Published online 2017 Apr 6. doi: 10.1152/ajplung.00008.2017

PMCID:: PMC5495943

Abstract Article

Select item 432321915.

Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor

Marina Koutsioumpa, Evangelia Poimenidi, Evangelia Pantazaka, Christina Theodoropoulou, Angeliki Skoura, Vasileios Megalooikonomou, Nelly Kieffer, Jose Courty, Shuji Mizumoto, Kazuyuki Sugahara, Evangelia Papadimitriou

Mol Cancer. 2015; 14(1): 19. Published online 2015 Feb 3. doi: 10.1186/s12943-015-0287-3

PMCID:: PMC4323219

Abstract Article PDF–3.5M

Select item 271157516.

VE-PTP controls blood vessel development by balancing Tie-2 activity

Mark Winderlich, Linda Keller, Giuseppe Cagna, Andre Broermann, Olena Kamenyeva, Friedemann Kiefer, Urban Deutsch, Astrid F. Nottebaum, Dietmar Vestweber

J Cell Biol. 2009 May 18; 185(4): 657–671. doi: 10.1083/jcb.200811159

PMCID:: PMC2711575

Abstract Article PDF–8.2M

Select item 12629317.

VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts

Roman Nawroth, Gregor Poell, Alexander Ranft, Stephan Kloep, Ulrike Samulowitz, Gregor Fachinger, Matthew Golding, David T. Shima, Urban Deutsch, Dietmar Vestweber

EMBO J. 2002 Sep 16; 21(18): 4885–4895. doi: 10.1093/emboj/cdf497