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Items: 1 to 20 of 25

1.
OVOL2 impairs RHO GTPase signaling to restrain mitosis and aggressiveness of Anaplastic Thyroid Cancer
Mila Gugnoni, Gloria Manzotti, Emanuele Vitale, Elisabetta Sauta, Federica Torricelli, Francesca Reggiani, Mariaelena Pistoni, Simonetta Piana, Alessia Ciarrocchi
J Exp Clin Cancer Res. 2022; 41: 108. Published online 2022 Mar 25. doi: 10.1186/s13046-022-02316-2
PMCID:
PMC8957195
ArticlePDF–7.2M
2.
Altered Epithelial-mesenchymal Plasticity as a Result of Ovol2 Deletion Minimally Impacts the Self-renewal of Adult Mammary Basal Epithelial Cells
Peng Sun, Yingying Han, Maksim Plikus, Xing Dai
J Mammary Gland Biol Neoplasia. 2021; 26(4): 377–386. Published online 2022 Jan 4. doi: 10.1007/s10911-021-09508-0
PMCID:
PMC8858298
ArticlePDF–7.8M
3.
OVOL2 induces mesenchymal-to-epithelial transition in fibroblasts and enhances cell-state reprogramming towards epithelial lineages
Kazuhide Watanabe, Ye Liu, Shuhei Noguchi, Madeleine Murray, Jen-Chien Chang, Mami Kishima, Hajime Nishimura, Kosuke Hashimoto, Aki Minoda, Harukazu Suzuki
Sci Rep. 2019; 9: 6490. Published online 2019 Apr 24. doi: 10.1038/s41598-019-43021-z
PMCID:
PMC6482152
ArticlePDF–2.5M
4.
OVOL2 links stemness and metastasis via fine-tuning epithelial-mesenchymal transition in nasopharyngeal carcinoma
Xue-Kang Qi, Hui-Qiong Han, Hao-Jiong Zhang, Miao Xu, Lili Li, Lin Chen, Tong Xiang, Qi-Sheng Feng, Tiebang Kang, Chao-Nan Qian, Mu-Yan Cai, Qian Tao, Yi-Xin Zeng, Lin Feng
Theranostics. 2018; 8(8): 2202–2216. Published online 2018 Mar 8. doi: 10.7150/thno.24003
PMCID:
PMC5928881
ArticlePDF–3.7M
5.
Confirmation of the OVOL2 Promoter Mutation c.-307T>C in Posterior Polymorphous Corneal Dystrophy 1
Doug D. Chung, Ricardo F. Frausto, Aleck E. Cervantes, Katherine M. Gee, Marina Zakharevich, Evelyn M. Hanser, Edwin M. Stone, Elise Heon, Anthony J. Aldave
PLoS One. 2017; 12(1): e0169215. Published online 2017 Jan 3. doi: 10.1371/journal.pone.0169215
PMCID:
PMC5207508
ArticlePDF–1.0M
6.
Autosomal-Dominant Corneal Endothelial Dystrophies CHED1 and PPCD1 Are Allelic Disorders Caused by Non-coding Mutations in the Promoter of OVOL2
Alice E. Davidson, Petra Liskova, Cerys J. Evans, Lubica Dudakova, Lenka Nosková, Nikolas Pontikos, Hana Hartmannová, Kateřina Hodaňová, Viktor Stránecký, Zbyněk Kozmík, Hannah J. Levis, Nwamaka Idigo, Noriaki Sasai, Geoffrey J. Maher, James Bellingham, Neyme Veli, Neil D. Ebenezer, Michael E. Cheetham, Julie T. Daniels, Caroline M.H. Thaung, Katerina Jirsova, Vincent Plagnol, Martin Filipec, Stanislav Kmoch, Stephen J. Tuft, Alison J. Hardcastle
Am J Hum Genet. 2016 Jan 7; 98(1): 75–89. Published online 2015 Dec 31. doi: 10.1016/j.ajhg.2015.11.018
PMCID:
PMC4716680
ArticlePDF–2.0M
7.
Transcription Factors OVOL1 and OVOL2 Induce the Mesenchymal to Epithelial Transition in Human Cancer
Hernan Roca, James Hernandez, Savannah Weidner, Richard C. McEachin, David Fuller, Sudha Sud, Taibriana Schumann, John E. Wilkinson, Alexander Zaslavsky, Hangwen Li, Christopher A. Maher, Stephanie Daignault-Newton, Patrick N. Healy, Kenneth J. Pienta
PLoS One. 2013; 8(10): e76773. Published online 2013 Oct 4. doi: 10.1371/journal.pone.0076773
PMCID:
PMC3790720
ArticlePDF–3.6M
8.
Exclusion of Positional Candidate Gene Coding Region Mutations in the Common Posterior Polymorphous Corneal Dystrophy 1 Candidate Gene Interval
Anthony J. Aldave, Vivek S. Yellore, Rosalind C. Vo, Khairidzan M. Kamal, Sylvia A. Rayner, Christopher L Plaisier, Michael C. Chen, Mausam R. Damani, Michele N. Pham, Michael B. Gorin, Eric Sobel, Jeanette Papp
Cornea. Author manuscript; available in PMC 2010 Aug 1.
Published in final edited form as: Cornea. 2009 Aug; 28(7): 801–807. doi: 10.1097/ICO.0b013e31819672fb
PMCID:
PMC2714875
ArticlePDF–445K
9.
Homozygosity mapping and linkage analysis demonstrate that autosomal recessive congenital hereditary endothelial dystrophy (CHED) and autosomal dominant CHED are genetically distinct
M. Callaghan, C. Hand, S. Kennedy, J FitzSimon, L. Collum, N. Parfrey
Br J Ophthalmol. 1999 Jan; 83(1): 115–119. doi: 10.1136/bjo.83.1.115
PMCID:
PMC1722772
SummaryPDF–112K
10.
OVOL2 antagonizes TGF-β signaling to regulate epithelial to mesenchymal transition during mammary tumor metastasis
Rong-Si Wu, Jing-Jing Hong, Jia-Fa Wu, Shen Yan, Di Wu, Na Liu, Qing-Feng Liu, Qiu-Wan Wu, Yuan-Yuan Xie, Yun-Jia Liu, Zhong-Zheng Zheng, Err-Cheng Chan, Zhi-Ming Zhang, Bo-An Li
Oncotarget. 2017 Jun 13; 8(24): 39401–39416. Published online 2017 Apr 11. doi: 10.18632/oncotarget.17031
PMCID:
PMC5503621
ArticlePDF–7.1M
11.
An NF-κB/OVOL2 circuit regulates glucose import and cell survival in non-small cell lung cancer
Rui Zhang, Guo-Jun Geng, Jian-Guang Guo, Yan-Jun Mi, Xiao-Lei Zhu, Ning Li, Hong-Ming Liu, Jun-Feng Lin, Jian-Weng Wang, Guang Zhao, Guan-Zhi Ye, Bo-An Li, Qi-Cong Luo, Jie Jiang
Cell Commun Signal. 2022; 20: 40. Published online 2022 Mar 28. doi: 10.1186/s12964-022-00845-z
PMCID:
PMC8962559
ArticlePDF–11M
12.
Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial–mesenchymal transition in diabetes
Daniel S. de Jesus, Tracy C.S. Mak, Yi-Fang Wang, Yorrick von Ohlen, Ying Bai, Eva Kane, Pauline Chabosseau, Catherine M. Chahrour, Walter Distaso, Victoria Salem, Alejandra Tomas, Markus Stoffel, Guy A. Rutter, Mathieu Latreille
Mol Metab. 2021 Nov; 53: 101248. Published online 2021 May 12. doi: 10.1016/j.molmet.2021.101248
PMCID:
PMC8184664
ArticlePDF–4.6M
13.
Ovol2, a Mammalian Homolog of Drosophila ovo: Gene Structure, Chromosomal Mapping, and Aberrant Expression in Blind-Sterile Mice
Baoan Li, Qian Dai, Ling Li, Mahalakshmi Nair, Douglas R. Mackay, Xing Dai
Genomics. Author manuscript; available in PMC 2010 Jun 29.
Published in final edited form as: Genomics. 2002 Sep; 80(3): 319–325. doi: 10.1006/geno.2002.6831
PMCID:
PMC2893385
ArticlePDF–975K
14.
Ovol2 Suppresses Cell Cycling and Terminal Differentiation of Keratinocytes by Directly Repressing c-Myc and Notch1
Julie Wells, Briana Lee, Anna Qianyao Cai, Adrine Karapetyan, Wan-Ju Lee, Elizabeth Rugg, Satrajit Sinha, Qing Nie, Xing Dai
J Biol Chem. 2009 Oct 16; 284(42): 29125–29135. Published online 2009 Aug 21. doi: 10.1074/jbc.M109.008847
PMCID:
PMC2781457
ArticlePDF–3.3M
15.
Molecular Phylogeny of OVOL Genes Illustrates a Conserved C2H2 Zinc Finger Domain Coupled by Hypervariable Unstructured Regions
Abhishek Kumar, Anita Bhandari, Rahul Sinha, Puspendu Sardar, Miss. Sushma, Pankaj Goyal, Chandan Goswami, Alessandro Grapputo
PLoS One. 2012; 7(6): e39399. Published online 2012 Jun 21. doi: 10.1371/journal.pone.0039399
PMCID:
PMC3380836
ArticlePDF–4.4M
16.
OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor
Chuannan Fan, Qian Wang, Gerard van der Zon, Jiang Ren, Cedrick Agaser, Roderick C. Slieker, Prasanna Vasudevan Iyengar, Hailiang Mei, Peter ten Dijke
Signal Transduct Target Ther. 2022; 7: 126. Published online 2022 Apr 29. doi: 10.1038/s41392-022-00944-w
PMCID:
PMC9050647
ArticlePDF–6.9M
17.
Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer
Xiujuan Zhang, Fei Luo, Shaliu Luo, Ling Li, Xinxin Ren, Jing Lin, Yingchun Liang, Chao Ma, Lihua Ding, Deyu Zhang, Tianxing Ye, Yanni Lin, Bilian Jin, Shan Gao, Qinong Ye
Adv Sci (Weinh) 2022 Sep; 9(27): 2200705. Published online 2022 Jul 27. doi: 10.1002/advs.202200705
PMCID:
PMC9507357
ArticlePDF–4.1M
18.
Bcl2-associated Athanogene 3 Interactome Analysis Reveals a New Role in Modulating Proteasome Activity
Ying Chen, Li-Na Yang, Li Cheng, Shun Tu, Shu-Juan Guo, Huang-Ying Le, Qian Xiong, Ran Mo, Chong-Yang Li, Jun-Seop Jeong, Lizhi Jiang, Seth Blackshaw, Li-Jun Bi, Heng Zhu, Sheng-Ce Tao, Feng Ge
Mol Cell Proteomics. 2013 Oct; 12(10): 2804–2819. Published online 2013 Jul 3. doi: 10.1074/mcp.M112.025882
PMCID:
PMC3790292
ArticlePDF–2.6M
19.
Impact of cytosine methylation on DNA binding specificities of human transcription factors
Yimeng Yin, Ekaterina Morgunova, Arttu Jolma, Eevi Kaasinen, Biswajyoti Sahu, Syed Khund-Sayeed, Pratyush K. Das, Teemu Kivioja, Kashyap Dave, Fan Zhong, Kazuhiro R. Nitta, Minna Taipale, Alexander Popov, Paul A. Ginno, Silvia Domcke, Jian Yan, Dirk Schübeler, Charles Vinson, Jussi Taipale
Science. Author manuscript; available in PMC 2021 Mar 30.
Published in final edited form as: Science. 2017 May 5; 356(6337): eaaj2239. doi: 10.1126/science.aaj2239
PMCID:
PMC8009048
ArticlePDF–2.6M
20.
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination
Nila Roy Choudhury, Gregory Heikel, Maryia Trubitsyna, Peter Kubik, Jakub Stanislaw Nowak, Shaun Webb, Sander Granneman, Christos Spanos, Juri Rappsilber, Alfredo Castello, Gracjan Michlewski
BMC Biol. 2017; 15: 105. Published online 2017 Nov 8. doi: 10.1186/s12915-017-0444-9
PMCID:
PMC5678581
ArticlePDF–3.2M

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