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Items: 13

1.
Mutation of SH2B3 (LNK), a GWAS candidate for hypertension, attenuates Dahl SS hypertension via inflammatory modulation
Nathan P. Rudemiller, Hayley Lund, Jessica R. C. Priestley, Bradley T. Endres, Jeremy W. Prokop, Howard J. Jacob, Aron M. Geurts, Eric P. Cohen, David L. Mattson
Hypertension. Author manuscript; available in PMC 2016 May 1.
Published in final edited form as: Hypertension. 2015 May; 65(5): 1111–1117. Published online 2015 Mar 16. doi: 10.1161/HYPERTENSIONAHA.114.04736
PMCID:
PMC4412596
AbstractArticlePDF–616K
2.
Cloning and characterization of Lnk, a signal transduction protein that links T-cell receptor activation signal to phospholipase C gamma 1, Grb2, and phosphatidylinositol 3-kinase.
X Huang, Y Li, K Tanaka, K G Moore, J I Hayashi
Proc Natl Acad Sci U S A. 1995 Dec 5; 92(25): 11618–11622. doi: 10.1073/pnas.92.25.11618
PMCID:
PMC40453
SummaryPage BrowsePDF–1.6M
3.
Recurrent Coding Sequence Variation Explains Only A Small Fraction of the Genetic Architecture of Colorectal Cancer
Maria N. Timofeeva, Ben Kinnersley, Susan M. Farrington, Nicola Whiffin, Claire Palles, Victoria Svinti, Amy Lloyd, Maggie Gorman, Li-Yin Ooi, Fay Hosking, Ella Barclay, Lina Zgaga, Sara Dobbins, Lynn Martin, Evropi Theodoratou, Peter Broderick, Albert Tenesa, Claire Smillie, Graeme Grimes, Caroline Hayward, Archie Campbell, David Porteous, Ian J. Deary, Sarah E. Harris, Emma L. Northwood, Jennifer H. Barrett, Gillian Smith, Roland Wolf, David Forman, Hans Morreau, Dina Ruano, Carli Tops, Juul Wijnen, Melanie Schrumpf, Arnoud Boot, Hans F A Vasen, Frederik J. Hes, Tom van Wezel, Andre Franke, Wolgang Lieb, Clemens Schafmayer, Jochen Hampe, Stephan Buch, Peter Propping, Kari Hemminki, Asta Försti, Helga Westers, Robert Hofstra, Manuela Pinheiro, Carla Pinto, Manuel Teixeira, Clara Ruiz-Ponte, Ceres Fernández-Rozadilla, Angel Carracedo, Antoni Castells, Sergi Castellví-Bel, Harry Campbell, D. Timothy Bishop, Ian P M Tomlinson, Malcolm G. Dunlop, Richard S. Houlston
Sci Rep. 2015; 5: 16286. Published online 2015 Nov 10. doi: 10.1038/srep16286
PMCID:
PMC4639776
AbstractArticlePDF–422K
4.
Creation and Preliminary Characterization of a Leptin Knockout Rat
Sergio Vaira, Chang Yang, Aaron McCoy, Kelly Keys, Shurong Xue, Edward J. Weinstein, Deborah V. Novack, Xiaoxia Cui
Endocrinology. 2012 Nov; 153(11): 5622–5628. Published online 2012 Sep 4. doi: 10.1210/en.2012-1462
PMCID:
PMC3473197
AbstractArticle
5.
Genetic Analysis of Adult-Onset Autoimmune Diabetes
Joanna M.M. Howson, Silke Rosinger, Deborah J. Smyth, Bernhard O. Boehm, the ADBW-END Study Group, John A. Todd
Diabetes. 2011 Oct; 60(10): 2645–2653. Published online 2011 Sep 16. doi: 10.2337/db11-0364
PMCID:
PMC3178303
AbstractArticlePDF–585K
6.
Novel mutations in the inhibitory adaptor protein LNK drive JAK-STAT signaling in patients with myeloproliferative neoplasms
Stephen T. Oh, Erin F. Simonds, Carol Jones, Matthew B. Hale, Yury Goltsev, Kenneth D. Gibbs, Jr, Jason D. Merker, James L. Zehnder, Garry P. Nolan, Jason Gotlib
Blood. 2010 Aug 12; 116(6): 988–992. Prepublished online 2010 Apr 19. doi: 10.1182/blood-2010-02-270108
PMCID:
PMC2924231
AbstractArticle
7.
The Adaptor Protein SH2B3 (Lnk) Negatively Regulates Neurite Outgrowth of PC12 Cells and Cortical Neurons
Tien-Cheng Wang, Hsun Chiu, Yu-Jung Chang, Tai-Yu Hsu, Ing-Ming Chiu, Linyi Chen
PLoS One. 2011; 6(10): e26433. Published online 2011 Oct 18. doi: 10.1371/journal.pone.0026433
PMCID:
PMC3196555
AbstractArticlePDF–2.1M
8.
LNK/SH2B3 Loss of Function Promotes Atherosclerosis and Thrombosis
Wei Wang, Yang Tang, Ying Wang, Liana Tascau, Joanna Balcerek, Wei Tong, Ross L. Levine, Carrie Welch, Alan R. Tall, Nan Wang
Circ Res. Author manuscript; available in PMC 2017 Sep 2.
Published in final edited form as: Circ Res. 2016 Sep 2; 119(6): e91–e103. Published online 2016 Jul 18. doi: 10.1161/CIRCRESAHA.116.308955
PMCID:
PMC5016083
AbstractArticlePDF–1.3M
9.
Lnk Inhibits Tpo–mpl Signaling and Tpo-mediated Megakaryocytopoiesis
Wei Tong, Harvey F. Lodish
J Exp Med. 2004 Sep 6; 200(5): 569–580. doi: 10.1084/jem.20040762
PMCID:
PMC2212736
AbstractArticlePDF–1.6M
10.
Enhanced Hematopoiesis by Hematopoietic Progenitor Cells Lacking Intracellular Adaptor Protein, Lnk
Satoshi Takaki, Hatsue Morita, Yoshinari Tezuka, Kiyoshi Takatsu
J Exp Med. 2002 Jan 21; 195(2): 151–160. doi: 10.1084/jem.20011170
Correction in:
J Exp Med. 2002 May 6; 195(9): 1229.
PMCID:
PMC2193601
AbstractArticlePDF–186K
11.
Regulation of Hematopoietic Development in the Aorta-Gonad-Mesonephros Region Mediated by Lnk Adaptor Protein
Ikuo Nobuhisa, Makiko Takizawa, Satoshi Takaki, Hirofumi Inoue, Keisuke Okita, Masaya Ueno, Kiyoshi Takatsu, Tetsuya Taga
Mol Cell Biol. 2003 Dec; 23(23): 8486–8494. doi: 10.1128/MCB.23.23.8486-8494.2003
PMCID:
PMC262659
AbstractArticlePDF–495K
12.
Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases
Vincent Plagnol, Joanna M. M. Howson, Deborah J. Smyth, Neil Walker, Jason P. Hafler, Chris Wallace, Helen Stevens, Laura Jackson, Matthew J. Simmonds, Type 1 Diabetes Genetics Consortium, Polly J. Bingley, Stephen C. Gough, John A. Todd
PLoS Genet. 2011 Aug; 7(8): e1002216. Published online 2011 Aug 4. doi: 10.1371/journal.pgen.1002216
PMCID:
PMC3150451
AbstractArticlePDF–132K
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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