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Select item 105061561.

Biallelic variants in ribonuclease inhibitor (RNH1), an inflammasome modulator, are associated with a distinctive subtype of acute, necrotizing encephalopathy

Vandana Shashi, Kelly Schoch, Rebecca Ganetzky, Peter G. Kranz, Neal Sondheimer, M. Louise Markert, Heidi Cope, Azita Sadeghpour, Philip Roehrs, Thomas Arbogast, Colleen Muraresku, Undiagnosed Diseases Network, Amanda V. Tyndall, Michael J. Esser, Kristine E. Woodward, Billie Ping-Yee Au, Jillian S. Parboosingh, Ryan E. Lamont, Francois P. Bernier, Nicola A.M. Wright, Susa M. Benseler, Simon J. Parsons, Mays El-Dairi, Edward C. Smith, Purnima Valdez, Michael Tennison, A. Micheil Innes, Erica E. Davis

Genet Med. Author manuscript; available in PMC 2024 Mar 1.

Published in final edited form as: Genet Med. 2023 Sep; 25(9): 100897. Published online 2023 May 13. doi: 10.1016/j.gim.2023.100897

PMCID:: PMC10506156

Abstract Article PDF–1.2M

Select item 104006332.

Functional status analysis of RNH1 in bladder cancer for predicting immunotherapy response

Sen Chen, Jun Ran, Zhouqian Fan, Mingyou Liu, Liang Wu, Qiude Li, Jian Peng, Zuquan Hu

Sci Rep. 2023; 13: 12625. Published online 2023 Aug 3. doi: 10.1038/s41598-023-39827-7

PMCID:: PMC10400633

Abstract Article PDF–15M

Select item 104006013.

Ribonuclease inhibitor 1 (RNH1) deficiency cause congenital cataracts and global developmental delay with infection-induced psychomotor regression and anemia

Carola Hedberg-Oldfors, Sanhita Mitra, Angela Molinaro, Kittichate Visuttijai, Linda Fogelstrand, Anders Oldfors, Fredrik H. Sterky, Niklas Darin

Eur J Hum Genet. 2023 Aug; 31(8): 887–894. Published online 2023 Mar 20. doi: 10.1038/s41431-023-01327-7

PMCID:: PMC10400601

Abstract Article PDF–1.9M

Select item 26056744.

Interaction of onconase with the human ribonuclease inhibitor protein

Rebecca F. Turcotte, Ronald T. Raines

Biochem Biophys Res Commun. Author manuscript; available in PMC 2009 Dec 12.

Published in final edited form as: Biochem Biophys Res Commun. 2008 Dec 12; 377(2): 512–514. Published online 2008 Oct 16. doi: 10.1016/j.bbrc.2008.10.032

PMCID:: PMC2605674

Abstract Article PDF–705K

Select item 25333135.

Intraspecies Regulation of Ribonucleolytic Activity

R. Jeremy Johnson, Luke D. Lavis, Ronald T. Raines

Biochemistry. Author manuscript; available in PMC 2008 Nov 13.

Published in final edited form as: Biochemistry. 2007 Nov 13; 46(45): 13131–13140. Published online 2007 Oct 23. doi: 10.1021/bi701521q

PMCID:: PMC2533313

Abstract Article PDF–2.2M

Select item 4551256.

The primary structure of human ribonuclease/angiogenin inhibitor (RAI) discloses a novel highly diversified protein superfamily with a common repetitive module.

R Schneider, E Schneider-Scherzer, M Thurnher, B Auer, M Schweiger

EMBO J. 1988 Dec 20; 7(13): 4151–4156. doi: 10.1002/j.1460-2075.1988.tb03310.x

PMCID:: PMC455125

Summary Page Browse PDF–1.3M

Select item 89220487.

LRR-protein RNH1 dampens the inflammasome activation and is associated with COVID-19 severity

Giuseppe Bombaci, Mayuresh Anant Sarangdhar, Nicola Andina, Aubry Tardivel, Eric Chi-Wang Yu, Gillian M Mackie, Matthew Pugh, Vedat Burak Ozan, Yara Banz, Thibaud Spinetti, Cedric Hirzel, Esther Youd, Joerg C Schefold, Graham Taylor, Amiq Gazdhar, Nicolas Bonadies, Anne Angelillo-Scherrer, Pascal Schneider, Kendle M Maslowski, Ramanjaneyulu Allam

Life Sci Alliance. 2022 Jun; 5(6): e202101226. Published online 2022 Mar 7. doi: 10.26508/lsa.202101226

PMCID:: PMC8922048

Abstract Article PDF–3.4M

Select item 78660528.

Angiogenin (ANG)—Ribonuclease Inhibitor (RNH1) System in Protein Synthesis and Disease

Mayuresh Anant Sarangdhar, Ramanjaneyulu Allam

Int J Mol Sci. 2021 Feb; 22(3): 1287. Published online 2021 Jan 28. doi: 10.3390/ijms22031287

PMCID:: PMC7866052

Abstract Article PDF–1.2M

Select item 61525309.

Regulation of IRE1 RNase activity by the Ribonuclease inhibitor 1 (RNH1)

Quentin Tavernier, Evangeline Bennana, Virginie Poindessous, Celine Schaeffer, Luca Rampoldi, Nicolas Pietrancosta, Nicolas Pallet

Cell Cycle. 2018; 17(15): 1901–1916. Published online 2018 Sep 5. doi: 10.1080/15384101.2018.1506655

PMCID:: PMC6152530

Abstract Article PDF–2.4M

Select item 514863110.

Knockout of the Ribonuclease Inhibitor Gene Leaves Human Cells Vulnerable to Secretory Ribonucleases

Sydney P. Thomas, Eunji Kim, Jin-Soo Kim, Ronald T. Raines

Biochemistry. Author manuscript; available in PMC 2016 Dec 9.

Published in final edited form as: Biochemistry. 2016 Nov 22; 55(46): 6359–6362. Published online 2016 Nov 8. doi: 10.1021/acs.biochem.6b01003

PMCID:: PMC5148631

Abstract Article PDF–335K

Select item 500628311.

Interplay between intergrin-linked kinase and ribonuclease inhibitor affects growth and metastasis of bladder cancer through signaling ILK pathways

Xiang Zhuang, Mengxin Lv, Zhenyu Zhong, Luyu Zhang, Rong Jiang, Junxia Chen

J Exp Clin Cancer Res. 2016; 35(1): 130. Published online 2016 Aug 30. doi: 10.1186/s13046-016-0408-x

PMCID:: PMC5006283

Abstract Article PDF–3.1M

Select item 398196112.

An endogenous ribonuclease inhibitor regulates the antimicrobial activity of ribonuclease 7 in the human urinary tract

John David Spencer, Andrew L. Schwaderer, Tad Eichler, Huanyu Wang, Jennifer Kline, Sheryl S. Justice, Daniel M. Cohen, David S. Hains

Kidney Int. Author manuscript; available in PMC 2014 Nov 1.

Published in final edited form as: Kidney Int. 2014 May; 85(5): 1179–1191. Published online 2013 Oct 9. doi: 10.1038/ki.2013.395

PMCID:: PMC3981961

Abstract Article PDF–1.3M

Select item 199390113.

Inhibition of Human Pancreatic Ribonuclease by the Human Ribonuclease Inhibitor Protein

R. Jeremy Johnson, Jason G. McCoy, Craig A. Bingman, George N. Phillips, Jr., Ronald T. Raines

J Mol Biol. Author manuscript; available in PMC 2007 Sep 25.

Published in final edited form as: J Mol Biol. 2007 Apr 27; 368(2): 434–449. Published online 2007 Feb 9. doi: 10.1016/j.jmb.2007.02.005

PMCID:: PMC1993901

Abstract Article PDF–2.2M

Select item 117014914.

Molecular recognition of human angiogenin by placental ribonuclease inhibitor--an X-ray crystallographic study at 2.0 A resolution.

A C Papageorgiou, R Shapiro, K R Acharya

EMBO J. 1997 Sep 1; 16(17): 5162–5177. doi: 10.1093/emboj/16.17.5162

PMCID:: PMC1170149

Summary PDF–1.1M

Select item 323058715.

PTEN Modulates miR-21 Processing via RNA-Regulatory Protein RNH1

Youn-Jae Kim, Se-Jeong Park, Eun Young Choi, Sol Kim, Hee Jin Kwak, Byong Chul Yoo, Heon Yoo, Seung-Hoon Lee, Daesoo Kim, Jong Bae Park, Jong Heon Kim

PLoS One. 2011; 6(12): e28308. Published online 2011 Dec 5. doi: 10.1371/journal.pone.0028308

PMCID:: PMC3230587

Abstract Article PDF–2.1M

Select item 30462416.

Human placental ribonuclease inhibitor abolishes both angiogenic and ribonucleolytic activities of angiogenin.

R Shapiro, B L Vallee

Proc Natl Acad Sci U S A. 1987 Apr; 84(8): 2238–2241. doi: 10.1073/pnas.84.8.2238

PMCID:: PMC304624

Summary Page Browse PDF–1.0M

Select item 587384617.

Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation

Vijaykumar Chennupati, Diogo F.T. Veiga, Kendle M. Maslowski, Nicola Andina, Aubry Tardivel, Eric Chi-Wang Yu, Martina Stilinovic, Cedric Simillion, Michel A. Duchosal, Manfredo Quadroni, Irene Roberts, Vijay G. Sankaran, H. Robson MacDonald, Nicolas Fasel, Anne Angelillo-Scherrer, Pascal Schneider, Trang Hoang, Ramanjaneyulu Allam

J Clin Invest. 2018 Apr 2; 128(4): 1597–1614. Published online 2018 Mar 19. doi: 10.1172/JCI94956

PMCID:: PMC5873846

Abstract Article PDF–17M

Select item 825766018.

USP9X-mediated KDM4C deubiquitination promotes lung cancer radioresistance by epigenetically inducing TGF-β2 transcription

Xiaohua Jie, William Pat Fong, Rui Zhou, Ye Zhao, Yingchao Zhao, Rui Meng, Sheng Zhang, Xiaorong Dong, Tao Zhang, Kunyu Yang, Gang Wu, Shuangbing Xu

Cell Death Differ. 2021 Jul; 28(7): 2095–2111. Published online 2021 Feb 8. doi: 10.1038/s41418-021-00740-z

PMCID:: PMC8257660

Abstract Article PDF–6.4M

Select item 620539619.

E-cadherin expression on multiple myeloma cells activates tumor-promoting properties in plasmacytoid DCs

Enguang Bi, Rong Li, Laura C. Bover, Haiyan Li, Pan Su, Xingzhe Ma, Chunjian Huang, Qiang Wang, Lintao Liu, Maojie Yang, Zhijuan Lin, Jianfei Qian, Weijun Fu, Yong-Jun Liu, Qing Yi

J Clin Invest. 2018 Nov 1; 128(11): 4821–4831. Published online 2018 Oct 2. doi: 10.1172/JCI121421

PMCID:: PMC6205396

Abstract Article PDF–5.0M

Select item 851323720.

Downregulation of the FBXO43 gene inhibits tumor growth in human breast cancer by limiting its interaction with PCNA

Rulan Ma, Kun Zhu, Dawei Yuan, Meijun Gong, Yijun Li, Kang Li, Lei Meng

J Transl Med. 2021; 19: 425. Published online 2021 Oct 13. doi: 10.1186/s12967-021-03100-0

PMCID:: PMC8513237

Abstract Article PDF–4.3M

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PMC Links for Gene (Select 6050) (109)
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Aged, lupus-prone MRL/Faslpr model: splenic CD4 T cells
Aged, lupus-prone MRL/Faslpr model: splenic CD4 T cells
Accession: GDS4190

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Related DataSets for GEO Profiles (Select 95419915) (1)
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Eois sp. Janzen49 cytochrome oxidase subunit 1 (COI) gene, partial cds; mitochon...
Eois sp. Janzen49 cytochrome oxidase subunit 1 (COI) gene, partial cds; mitochondrial
gi|374914760|gnl|uoguelph|MHMYM1048 OI-5P|gb|JQ526138.1|

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