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Items: 1 to 20 of 64

1.
MRPS25 mutations impair mitochondrial translation and cause encephalomyopathy
Enrico Bugiardini, Alice L Mitchell, Ilaria Dalla Rosa, Hue-Tran Horning-Do, Alan M Pitmann, Olivia V Poole, Janice L Holton, Sachit Shah, Cathy Woodward, Iain Hargreaves, Rosaline Quinlivan, Alexey Amunts, Rudolf J Wiesner, Henry Houlden, Ian J Holt, Michael G Hanna, Robert D S Pitceathly, Antonella Spinazzola
Hum Mol Genet. 2019 Aug 15; 28(16): 2711–2719. Published online 2019 Apr 30. doi: 10.1093/hmg/ddz093
PMCID:
PMC6687946
AbstractArticlePDF–12M
2.
GRSF1 Regulates RNA Processing in Mitochondrial RNA Granules
Alexis A. Jourdain, Mirko Koppen, Mateusz Wydro, Chris D. Rodley, Robert N. Lightowlers, Zofia M. Chrzanowska-Lightowlers, Jean-Claude Martinou
Cell Metab. 2013 Mar 5; 17(3): 399–410. doi: 10.1016/j.cmet.2013.02.005
PMCID:
PMC3593211
AbstractArticlePDF–2.1M
3.
p32/gC1qR is indispensable for fetal development and mitochondrial translation: importance of its RNA-binding ability
Mikako Yagi, Takeshi Uchiumi, Shinya Takazaki, Bungo Okuno, Masatoshi Nomura, Shin-ichi Yoshida, Tomotake Kanki, Dongchon Kang
Nucleic Acids Res. 2012 Oct; 40(19): 9717–9737. Published online 2012 Aug 13. doi: 10.1093/nar/gks774
PMCID:
PMC3479211
AbstractArticlePDF–6.0M
4.
LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF‐κB to the nucleus
Zhixiao Wu, Lena A Berlemann, Verian Bader, Dominik A Sehr, Eva Dawin, Alberto Covallero, Jens Meschede, Lena Angersbach, Cathrin Showkat, Jonas B Michaelis, Christian Münch, Bettina Rieger, Dmitry Namgaladze, Maria Georgina Herrera, Fabienne C Fiesel, Wolfdieter Springer, Marta Mendes, Jennifer Stepien, Katalin Barkovits, Katrin Marcus, Albert Sickmann, Gunnar Dittmar, Karin B Busch, Dietmar Riedel, Marisa Brini, Jörg Tatzelt, Tito Cali, Konstanze F Winklhofer
EMBO J. 2022 Dec; 41(24): e112006. Published online 2022 Nov 18. doi: 10.15252/embj.2022112006
PMCID:
PMC9753471
AbstractArticlePDF–4.3M
5.
The structure of the human mitochondrial ribosome
Alexey Amunts, Alan Brown, Jaan Toots, Sjors H. W. Scheres, V. Ramakrishnan
Science. Author manuscript; available in PMC 2015 Oct 3.
Published in final edited form as: Science. 2015 Apr 3; 348(6230): 95–98. Published online 2015 Apr 2. doi: 10.1126/science.aaa1193
PMCID:
PMC4501431
AbstractArticlePDF–1.7M
6.
Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation
Frauke Liebelt, Joost Schimmel, Matty Verlaan – de Vries, Esra Klemann, Martin E van Royen, Yana van der Weegen, Martijn S Luijsterburg, Leon H Mullenders, Alex Pines, Wim Vermeulen, Alfred C O Vertegaal
Nucleic Acids Res. 2020 Jan 10; 48(1): 231–248. Published online 2019 Nov 13. doi: 10.1093/nar/gkz977
PMCID:
PMC7145520
AbstractArticlePDF–7.6M
7.
The human regulatory protein Ki-1/57 is a target of SUMOylation and affects PML nuclear bodies formation
Ângela Saito, Edmarcia E. Souza, Fernanda C. Costa, Gabriela V. Meirelles, Kaliandra A. Gonçalves, Marcos T. Santos, Gustavo C. Bressan, Mark E. McComb, Catherine E. Costello, Stephen A. Whelan, Jörg Kobarg
J Proteome Res. Author manuscript; available in PMC 2019 Aug 19.
Published in final edited form as: J Proteome Res. 2017 Sep 1; 16(9): 3147–3157. Published online 2017 Jul 31. doi: 10.1021/acs.jproteome.7b00001
PMCID:
PMC6699623
AbstractArticlePDF–1.0M
8.
A protein-RNA interaction atlas of the ribosome biogenesis factor AATF
Rainer W. J. Kaiser, Michael Ignarski, Eric L. Van Nostrand, Christian K. Frese, Manaswita Jain, Sadrija Cukoski, Heide Heinen, Melanie Schaechter, Lisa Seufert, Konstantin Bunte, Peter Frommolt, Patrick Keller, Mark Helm, Katrin Bohl, Martin Höhne, Bernhard Schermer, Thomas Benzing, Katja Höpker, Christoph Dieterich, Gene W. Yeo, Roman-Ulrich Müller, Francesca Fabretti
Sci Rep. 2019; 9: 11071. Published online 2019 Jul 30. doi: 10.1038/s41598-019-47552-3
PMCID:
PMC6667500
AbstractArticlePDF–2.8M
9.
The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking
Ruxandra Bachmann-Gagescu, Margo Dona, Lisette Hetterschijt, Edith Tonnaer, Theo Peters, Erik de Vrieze, Dorus A. Mans, Sylvia E. C. van Beersum, Ian G. Phelps, Heleen H. Arts, Jan E. Keunen, Marius Ueffing, Ronald Roepman, Karsten Boldt, Dan Doherty, Cecilia B. Moens, Stephan C. F. Neuhauss, Hannie Kremer, Erwin van Wijk
PLoS Genet. 2015 Oct; 11(10): e1005575. Published online 2015 Oct 20. doi: 10.1371/journal.pgen.1005575
PMCID:
PMC4617701
AbstractArticlePDF–13M
10.
Mitochondrial ClpP-mediated proteolysis induces selective cancer cell lethality
Jo Ishizawa, Sarah F. Zarabi, R. Eric Davis, Ondrej Halgas, Takenobu Nii, Yulia Jitkova, Ran Zhao, Jonathan St-Germain, Lauren E. Heese, Grace Egan, Vivian R. Ruvolo, Samir H. Barghout, Yuki Nishida, Rose Hurren, Wencai Ma, Marcela Gronda, Todd Link, Keith Wong, Mark Mabanglo, Kensuke Kojima, Gautam Borthakur, Neil MacLean, John Man Chun Ma, Andrew B. Leber, Mark D. Minden, Walid Houry, Hagop Kantarjian, Martin Stogniew, Brian Raught, Emil F. Pai, Aaron D. Schimmer, Michael Andreeff
Cancer Cell. Author manuscript; available in PMC 2020 May 13.
Published in final edited form as: Cancer Cell. 2019 May 13; 35(5): 721–737.e9. Published online 2019 May 2. doi: 10.1016/j.ccell.2019.03.014
PMCID:
PMC6620028
AbstractArticlePDF–2.9M
11.
A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome
Ricarda Richter, Joanna Rorbach, Aleksandra Pajak, Paul M Smith, Hans J Wessels, Martijn A Huynen, Jan A Smeitink, Robert N Lightowlers, Zofia M Chrzanowska-Lightowlers
EMBO J. 2010 Mar 17; 29(6): 1116–1125. Published online 2010 Feb 25. doi: 10.1038/emboj.2010.14
PMCID:
PMC2845271
AbstractArticlePDF–1.3M
12.
MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
Gayoung Seo, Han Han, Rebecca Elizabeth Vargas, Bing Yang, Xu Li, Wenqi Wang
Cell Rep. Author manuscript; available in PMC 2020 Jul 25.
Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107860. doi: 10.1016/j.celrep.2020.107860
PMCID:
PMC7382313
AbstractArticlePDF–2.6M
13.
The deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival
Yuanming He, Siyu Wang, Jiefei Tong, Shuoyi Jiang, Ye Yang, Zubin Zhang, Yujia Xu, Yuanying Zeng, Biyin Cao, Michael F. Moran, Xinliang Mao
J Biol Chem. 2020 Feb 14; 295(7): 2084–2096. Published online 2019 Dec 10. doi: 10.1074/jbc.RA119.010724
PMCID:
PMC7029123
AbstractArticlePDF–3.6M
14.
A conserved acetylation switch enables pharmacological control of tubby-like protein stability
Evan M. Kerek, Kevin H. Yoon, Shu Y. Luo, Jerry Chen, Robert Valencia, Olivier Julien, Andrew J. Waskiewicz, Basil P. Hubbard
J Biol Chem. 2021 Jan-Jun; 296: 100073. Published online 2020 Nov 23. doi: 10.1074/jbc.RA120.015839
PMCID:
PMC7948452
AbstractArticlePDF–3.6M
15.
Interactome and proteome dynamics uncover immune modulatory associations of the pathogen sensing factor cGAS
Krystal K. Lum, Bokai Song, Joel D. Federspiel, Benjamin A. Diner, Timothy Howard, Ileana M. Cristea
Cell Syst. Author manuscript; available in PMC 2019 Dec 26.
Published in final edited form as: Cell Syst. 2018 Dec 26; 7(6): 627–642.e6. Published online 2018 Nov 21. doi: 10.1016/j.cels.2018.10.010
PMCID:
PMC6310102
AbstractArticlePDF–3.5M
16.
Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms
Jiannong Li, Keiryn Bennett, Alexey Stukalov, Bin Fang, Guolin Zhang, Takeshi Yoshida, Isamu Okamoto, Jae-Young Kim, Lanxi Song, Yun Bai, Xiaoning Qian, Bhupendra Rawal, Michael Schell, Florian Grebien, Georg Winter, Uwe Rix, Steven Eschrich, Jacques Colinge, John Koomen, Giulio Superti-Furga, Eric B Haura
Mol Syst Biol. 2013; 9: 705. Published online 2013 Nov 5. doi: 10.1038/msb.2013.61
PMCID:
PMC4039310
AbstractArticlePDF–3.2M
17.
KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II
Ryan P. McNamara, Jonathan E. Reeder, Elizabeth A. McMillan, Curtis W. Bacon, Jennifer L. McCann, Iván D’Orso
Mol Cell. Author manuscript; available in PMC 2017 Jan 7.
Published in final edited form as: Mol Cell. 2016 Jan 7; 61(1): 39–53. Published online 2015 Dec 24. doi: 10.1016/j.molcel.2015.11.004
PMCID:
PMC4714561
AbstractArticlePDF–2.2M
18.
A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing
David E. Gordon, Gwendolyn M. Jang, Mehdi Bouhaddou, Jiewei Xu, Kirsten Obernier, Kris M. White, Matthew J. O’Meara, Veronica V. Rezelj, Jeffrey Z. Guo, Danielle L. Swaney, Tia A. Tummino, Ruth Huettenhain, Robyn M. Kaake, Alicia L. Richards, Beril Tutuncuoglu, Helene Foussard, Jyoti Batra, Kelsey Haas, Maya Modak, Minkyu Kim, Paige Haas, Benjamin J. Polacco, Hannes Braberg, Jacqueline M. Fabius, Manon Eckhardt, Margaret Soucheray, Melanie J. Bennett, Merve Cakir, Michael J. McGregor, Qiongyu Li, Bjoern Meyer, Ferdinand Roesch, Thomas Vallet, Alice Mac Kain, Lisa Miorin, Elena Moreno, Zun Zar Chi Naing, Yuan Zhou, Shiming Peng, Ying Shi, Ziyang Zhang, Wenqi Shen, Ilsa T. Kirby, James E. Melnyk, John S. Chorba, Kevin Lou, Shizhong A. Dai, Inigo Barrio-Hernandez, Danish Memon, Claudia Hernandez-Armenta, Jiankun Lyu, Christopher J.P. Mathy, Tina Perica, Kala B. Pilla, Sai J. Ganesan, Daniel J. Saltzberg, Ramachandran Rakesh, Xi Liu, Sara B. Rosenthal, Lorenzo Calviello, Srivats Venkataramanan, Jose Liboy-Lugo, Yizhu Lin, Xi-Ping Huang, YongFeng Liu, Stephanie A. Wankowicz, Markus Bohn, Maliheh Safari, Fatima S. Ugur, Cassandra Koh, Nastaran Sadat Savar, Quang Dinh Tran, Djoshkun Shengjuler, Sabrina J Fletcher, Michael C. O’Neal, Yiming Cai, Jason C.J.Chang, David J. Broadhurst, Saker Klippsten, Phillip P. Sharp, Nicole A. Wenzell, Duygu Kuzuoglu, Hao-Yuan Wang, Raphael Trenker, Janet M. Young, Devin A. Cavero, Joseph Hiatt, Theodore L. Roth, Ujjwal Rathore, Advait Subramanian, Julia Noack, Mathieu Hubert, Robert M. Stroud, Alan D. Frankel, Oren S. Rosenberg, Kliment A Verba, David A. Agard, Melanie Ott, Michael Emerman, Natalia Jura, Mark von Zastrow, Eric Verdin, Alan Ashworth, Olivier Schwartz, Christophe d’Enfert, Shaeri Mukherjee, Matt Jacobson, Harmit S. Malik, Danica G. Fujimori, Trey Ideker, Charles S. Craik, Stephen N. Floor, James S. Fraser, John D. Gross, Andrej Sali, Bryan L. Roth, Davide Ruggero, Jack Taunton, Tanja Kortemme, Pedro Beltrao, Marco Vignuzzi, Adolfo García-Sastre, Kevan M. Shokat, Brian K. Shoichet, Nevan J. Krogan
Nature. Author manuscript; available in PMC 2020 Oct 30.
Published in final edited form as: Nature. 2020 Jul; 583(7816): 459–468. Published online 2020 Apr 30. doi: 10.1038/s41586-020-2286-9
PMCID:
PMC7431030
AbstractArticlePDF–7.7M
19.
Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2
Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang
J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22
PMCID:
PMC9972945
AbstractArticlePDF–3.0M
20.
The cell proliferation antigen Ki-67 organises heterochromatin
Michal Sobecki, Karim Mrouj, Alain Camasses, Nikolaos Parisis, Emilien Nicolas, David Llères, François Gerbe, Susana Prieto, Liliana Krasinska, Alexandre David, Manuel Eguren, Marie-Christine Birling, Serge Urbach, Sonia Hem, Jérôme Déjardin, Marcos Malumbres, Philippe Jay, Vjekoslav Dulic, Denis LJ Lafontaine, Robert Feil, Daniel Fisher
eLife. 2016; 5: e13722. Published online 2016 Mar 7. doi: 10.7554/eLife.13722
PMCID:
PMC4841783
AbstractArticlePDF–5.1M

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